TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3) - Rat Genome Database

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Gene: TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3) Chlorocebus sabaeus
Analyze
Symbol: TAB3
Name: TGF-beta activated kinase 1 (MAP3K7) binding protein 3
RGD ID: 18716269
Description: ENCODES a protein that exhibits K63-linked polyubiquitin modification-dependent protein binding (inferred); metal ion binding (inferred); molecular adaptor activity (inferred); INVOLVED IN defense response to bacterium (inferred); non-canonical NF-kappaB signal transduction (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Duchenne muscular dystrophy (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TGF-beta activated kinase 1 and MAP3K7 binding protein 3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X29,256,176 - 29,318,129 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX29,256,104 - 29,288,960 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605631,321,989 - 31,383,983 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TAB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X29,256,176 - 29,318,129 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX29,256,104 - 29,288,960 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605631,321,989 - 31,383,983 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TAB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,827,442 - 30,889,254 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX30,827,442 - 30,975,084 (-)EnsemblGRCh38hg38GRCh38
GRCh37X30,845,559 - 30,907,371 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,755,480 - 30,817,432 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX34,973,775 - 35,018,119 (-)NCBICelera
Cytogenetic MapXp21.2NCBI
HuRefX28,586,659 - 28,648,837 (-)NCBIHuRef
CHM1_1X30,877,115 - 30,938,957 (-)NCBICHM1_1
T2T-CHM13v2.0X30,425,653 - 30,487,452 (-)NCBIT2T-CHM13v2.0
Tab3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X84,617,466 - 84,678,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX84,617,628 - 84,678,075 (+)EnsemblGRCm39 Ensembl
GRCm38X85,573,854 - 85,634,469 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX85,574,022 - 85,634,469 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X82,819,361 - 82,879,808 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X81,826,741 - 81,887,033 (+)NCBIMGSCv36mm8
CeleraX76,769,488 - 76,829,957 (+)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.32NCBI
Tab3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X53,923,473 - 53,995,777 (+)NCBIGRCr8
mRatBN7.2X49,972,414 - 50,044,658 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX49,972,330 - 50,042,056 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X54,035,958 - 54,090,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,062,935 - 54,086,339 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X54,239,856 - 54,291,761 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X72,264,496 - 72,304,801 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX50,603,539 - 50,675,711 (+)NCBICelera
Cytogenetic MapXq21NCBI
Tab3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555353,585,243 - 3,612,790 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555353,547,556 - 3,612,705 (+)NCBIChiLan1.0ChiLan1.0
TAB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X32,629,664 - 32,691,003 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X32,633,201 - 32,694,372 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X23,428,343 - 23,489,688 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X30,980,841 - 31,042,142 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX30,980,841 - 31,012,994 (-)Ensemblpanpan1.1panPan2
TAB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X25,950,071 - 26,039,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX25,954,145 - 26,008,169 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX30,925,754 - 31,014,854 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X25,981,434 - 26,070,564 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX25,981,444 - 26,070,578 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X26,026,007 - 26,115,373 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X26,019,013 - 26,108,164 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X26,116,786 - 26,206,101 (-)NCBIUU_Cfam_GSD_1.0
Tab3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X18,767,914 - 18,825,442 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365536,860,261 - 6,885,475 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365536,860,435 - 6,917,796 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX26,632,551 - 26,729,051 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X26,632,547 - 26,729,039 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X28,950,771 - 29,007,946 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Tab3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476225,107,234 - 25,177,268 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 23 20
Low 13 20 40
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007991358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007991365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_037986447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005236386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005236387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_497003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_497004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_497005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC239181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACDXN010000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000012258   ⟹   ENSCSAP00000010301
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX29,256,104 - 29,288,960 (-)Ensembl
RefSeq Acc Id: XM_007991358   ⟹   XP_007989549
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X29,256,176 - 29,318,129 (-)NCBI
Vero_WHO_p1.0NW_02366605631,321,989 - 31,383,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037986439   ⟹   XP_037842367
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,383,983 (-)NCBI
RefSeq Acc Id: XM_037986440   ⟹   XP_037842368
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,383,887 (-)NCBI
RefSeq Acc Id: XM_037986441   ⟹   XP_037842369
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,383,887 (-)NCBI
RefSeq Acc Id: XM_037986442   ⟹   XP_037842370
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,383,887 (-)NCBI
RefSeq Acc Id: XM_037986443   ⟹   XP_037842371
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,383,980 (-)NCBI
RefSeq Acc Id: XM_037986444   ⟹   XP_037842372
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,354,458 (-)NCBI
RefSeq Acc Id: XM_037986445   ⟹   XP_037842373
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,321,989 - 31,383,983 (-)NCBI
RefSeq Acc Id: XM_037986446   ⟹   XP_037842374
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,321,989 - 31,383,983 (-)NCBI
RefSeq Acc Id: XM_037986447   ⟹   XP_037842375
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,330,132 - 31,350,798 (-)NCBI
RefSeq Acc Id: XR_005236386
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,328,331 - 31,383,983 (-)NCBI
RefSeq Acc Id: XR_005236387
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605631,326,002 - 31,383,983 (-)NCBI
RefSeq Acc Id: XR_497005
Type: NON-CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X29,265,217 - 29,296,367 (-)NCBI
Vero_WHO_p1.0NW_02366605631,331,028 - 31,383,983 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_007989549   ⟸   XM_007991358
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RNW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000010301   ⟸   ENSCSAT00000012258
RefSeq Acc Id: XP_037842373   ⟸   XM_037986445
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037842374   ⟸   XM_037986446
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037842367   ⟸   XM_037986439
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842371   ⟸   XM_037986443
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842370   ⟸   XM_037986442
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842369   ⟸   XM_037986441
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842368   ⟸   XM_037986440
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842372   ⟸   XM_037986444
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037842375   ⟸   XM_037986447
- Peptide Label: isoform X6


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012258.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/TrEMBL
InterPro CUE UniProtKB/TrEMBL
  TAB2/3_CUE UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
KEGG Report csab:103231769 UniProtKB/TrEMBL
NCBI Gene TAB3 ENTREZGENE
PANTHER TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 3 UniProtKB/TrEMBL
  TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB UniProtKB/TrEMBL
Pfam CUE UniProtKB/TrEMBL
PROSITE CUE UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART CUE UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP SSF90209 UniProtKB/TrEMBL
UniProt A0A0D9RNW2 ENTREZGENE, UniProtKB/TrEMBL