Pramel25 (PRAME like 25) - Rat Genome Database

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Pathways
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Gene: Pramel25 (PRAME like 25) Mus musculus
Analyze
No known orthologs.
Symbol: Pramel25
Name: PRAME like 25
RGD ID: 1619892
MGI Page MGI
Description: Predicted to be active in cytoplasm. Is expressed in 2-cell stage embryo.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC084594; Gm13023; hypothetical protein LOC194227; MGC91194; MGC:91194; novel protein similar to oogenesin (Oog) family; oogenesin-like; predicted gene 13023; RP23-281O10.1; uncharacterized protein LOC194227
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394143,515,904 - 143,522,155 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4143,515,922 - 143,522,145 (+)EnsemblGRCm39 Ensembl
GRCm384143,789,334 - 143,795,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4143,789,352 - 143,795,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv374143,379,237 - 143,385,488 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364143,056,049 - 143,062,261 (+)NCBIMGSCv36mm8
Celera4148,423,295 - 148,429,546 (+)NCBICelera
Cytogenetic Map4E1NCBI
cM Map477.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21565611   PMID:21731673   PMID:21873635  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:712
Count of miRNA genes:412
Interacting mature miRNAs:460
Transcripts:ENSMUST00000085144, ENSMUST00000105770, ENSMUST00000139978, ENSMUST00000149739
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse

Markers in Region
Oog1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12D2UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map4E1UniSTS
cM Map12 UniSTS
Gm13023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4E1UniSTS
cM Map477.96UniSTS
Gm13023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12D2UniSTS
Cytogenetic Map4E1UniSTS
Gm13023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12D2UniSTS
Cytogenetic Map4E1UniSTS
Gm13023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12D2UniSTS
Cytogenetic Map4E1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000085144   ⟹   ENSMUSP00000082232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4143,515,922 - 143,522,145 (+)Ensembl
GRCm38.p6 Ensembl4143,789,352 - 143,795,575 (+)Ensembl
RefSeq Acc Id: ENSMUST00000105770   ⟹   ENSMUSP00000101396
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4143,515,935 - 143,521,609 (+)Ensembl
GRCm38.p6 Ensembl4143,789,365 - 143,795,039 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139978
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4143,515,934 - 143,521,862 (+)Ensembl
GRCm38.p6 Ensembl4143,789,364 - 143,795,292 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149739   ⟹   ENSMUSP00000115387
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4143,515,935 - 143,521,329 (+)Ensembl
GRCm38.p6 Ensembl4143,789,365 - 143,794,759 (+)Ensembl
RefSeq Acc Id: NM_001007077   ⟹   NP_001007078
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394143,515,904 - 143,522,155 (+)NCBI
GRCm384143,789,334 - 143,795,585 (+)ENTREZGENE
MGSCv374143,379,237 - 143,385,488 (+)RGD
Celera4148,423,295 - 148,429,546 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001347246   ⟹   NP_001334175
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394143,515,904 - 143,522,155 (+)NCBI
GRCm384143,789,334 - 143,795,585 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001007078   ⟸   NM_001007077
- Peptide Label: isoform 1
- UniProtKB: A2A8N2 (UniProtKB/TrEMBL),   Q3UX09 (UniProtKB/TrEMBL),   Q5XG66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334175   ⟸   NM_001347246
- Peptide Label: isoform 2
- UniProtKB: A6PWA5 (UniProtKB/TrEMBL),   A6PWB4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000101396   ⟸   ENSMUST00000105770
RefSeq Acc Id: ENSMUSP00000082232   ⟸   ENSMUST00000085144
RefSeq Acc Id: ENSMUSP00000115387   ⟸   ENSMUST00000149739

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2A8N2-F1-model_v2 AlphaFold A2A8N2 1-498 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3650478 AgrOrtholog
Ensembl Genes ENSMUSG00000066031 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000085144 ENTREZGENE
  ENSMUST00000085144.11 UniProtKB/TrEMBL
  ENSMUST00000105770 ENTREZGENE
  ENSMUST00000105770.2 UniProtKB/TrEMBL
  ENSMUST00000149739.2 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  PRAME_family UniProtKB/TrEMBL
KEGG Report mmu:194227 UniProtKB/TrEMBL
MGD MGI:3650478 ENTREZGENE
NCBI Gene 194227 ENTREZGENE
PANTHER OOG4 PROTEIN-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel25 PhenoGen
PIRSF PRAME UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A2A8N2 ENTREZGENE, UniProtKB/TrEMBL
  A6PWA4_MOUSE UniProtKB/TrEMBL
  A6PWA5 ENTREZGENE, UniProtKB/TrEMBL
  A6PWB4 ENTREZGENE
  Q3UX09 ENTREZGENE, UniProtKB/TrEMBL
  Q5XG66 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-06-19 Pramel25  PRAME like 25  Gm13023  predicted gene 13023  Symbol and/or name change 5135510 APPROVED