MIR483 (microRNA 483) - Rat Genome Database
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Gene: MIR483 (microRNA 483) Homo sapiens
Analyze
Symbol: MIR483
Name: microRNA 483
RGD ID: 1604868
HGNC Page HGNC
Description: Predicted to be involved in cell aging and response to oxygen levels.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-483; mir-483; MIRN483
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl112,134,134 - 2,134,209 (-)EnsemblGRCh38hg38GRCh38
GRCh38112,134,134 - 2,134,209 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,155,364 - 2,155,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,111,939 - 2,112,014 (-)NCBINCBI36hg18NCBI36
Celera112,191,870 - 2,191,945 (-)NCBI
Cytogenetic Map11p15.5NCBI
CHM1_1112,153,988 - 2,154,063 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15978578   PMID:16381832   PMID:17604727   PMID:20388800   PMID:21037258   PMID:21112326   PMID:21146586   PMID:21676945   PMID:21893058   PMID:22101077   PMID:22223106   PMID:22465663  
PMID:22719975   PMID:22850566   PMID:22908386   PMID:23431031   PMID:23756429   PMID:24067364   PMID:24102952   PMID:24238045   PMID:24298054   PMID:24976017   PMID:25216866   PMID:25384963  
PMID:25531302   PMID:25601461   PMID:25622783   PMID:25738598   PMID:25843291   PMID:25991015   PMID:26020509   PMID:26124009   PMID:26224475   PMID:26283014   PMID:26403328   PMID:26747772  
PMID:26801660   PMID:26801758   PMID:26864161   PMID:27120784   PMID:27366946   PMID:27511210   PMID:27693430   PMID:28139355   PMID:28179587   PMID:28211800   PMID:28244607   PMID:28534971  
PMID:28727371   PMID:28924102   PMID:29090971   PMID:29141233   PMID:29207103   PMID:29371048   PMID:29516499   PMID:29717264   PMID:29788742   PMID:30073757   PMID:30171257   PMID:30173777  
PMID:30602302   PMID:30623425   PMID:30664712   PMID:30798328   PMID:30861353   PMID:30915751   PMID:30940435   PMID:31508813   PMID:31706013   PMID:31763724   PMID:31792031   PMID:31801112  
PMID:31926493   PMID:32206064  


Genomics

Comparative Map Data
MIR483
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl112,134,134 - 2,134,209 (-)EnsemblGRCh38hg38GRCh38
GRCh38112,134,134 - 2,134,209 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37112,155,364 - 2,155,439 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,111,939 - 2,112,014 (-)NCBINCBI36hg18NCBI36
Celera112,191,870 - 2,191,945 (-)NCBI
Cytogenetic Map11p15.5NCBI
CHM1_1112,153,988 - 2,154,063 (-)NCBICHM1_1
Mir483
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397142,208,661 - 142,208,733 (-)NCBIGRCm39mm39
GRCm387142,654,924 - 142,654,996 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,654,924 - 142,654,996 (-)EnsemblGRCm38mm10GRCm38
MGSCv377149,840,829 - 149,840,901 (-)NCBIGRCm37mm9NCBIm37
Celera7142,411,260 - 142,411,332 (-)NCBICelera
Cytogenetic Map7F5NCBI

Position Markers
ECD00298  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,257 - 2,157,173UniSTSGRCh37
Build 36112,112,833 - 2,113,749RGDNCBI36
Celera112,192,763 - 2,193,680RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,778 - 1,947,694UniSTS
ECD00602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,340 - 2,156,238UniSTSGRCh37
Build 36112,111,916 - 2,112,814RGDNCBI36
Celera112,191,846 - 2,192,744RGD
Cytogenetic Map11p15.5UniSTS
REN116999  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,070 - 2,155,294UniSTSGRCh37
Build 36112,111,646 - 2,111,870RGDNCBI36
Celera112,191,576 - 2,191,800RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,945,603 - 1,945,827UniSTS
REN117000  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,365 - 2,155,599UniSTSGRCh37
Build 36112,111,941 - 2,112,175RGDNCBI36
Celera112,191,871 - 2,192,105RGD
Cytogenetic Map11p15.5UniSTS
REN117001  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,575 - 2,155,819UniSTSGRCh37
Build 36112,112,151 - 2,112,395RGDNCBI36
Celera112,192,081 - 2,192,325RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,096 - 1,946,340UniSTS
REN117002  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,803 - 2,156,039UniSTSGRCh37
Build 36112,112,379 - 2,112,615RGDNCBI36
Celera112,192,309 - 2,192,545RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,324 - 1,946,560UniSTS
REN117003  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,016 - 2,156,265UniSTSGRCh37
Build 36112,112,592 - 2,112,841RGDNCBI36
Celera112,192,522 - 2,192,771RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,537 - 1,946,786UniSTS
REN117004  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,288 - 2,156,516UniSTSGRCh37
Build 36112,112,864 - 2,113,092RGDNCBI36
Celera112,192,794 - 2,193,022RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,809 - 1,947,037UniSTS
REN117005  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,495 - 2,156,735UniSTSGRCh37
Build 36112,113,071 - 2,113,311RGDNCBI36
Celera112,193,001 - 2,193,242RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,947,016 - 1,947,256UniSTS
REN117006  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,716 - 2,156,973UniSTSGRCh37
Build 36112,113,292 - 2,113,549RGDNCBI36
Celera112,193,223 - 2,193,480RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,947,237 - 1,947,494UniSTS
REN117007  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,964 - 2,157,232UniSTSGRCh37
Build 36112,113,540 - 2,113,808RGDNCBI36
Celera112,193,471 - 2,193,739RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,947,485 - 1,947,753UniSTS
stSG548714  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,154,924 - 2,155,105UniSTSGRCh37
Build 36112,111,500 - 2,111,681RGDNCBI36
Celera112,191,430 - 2,191,611RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,945,457 - 1,945,638UniSTS
stSG548715  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,131 - 2,156,480UniSTSGRCh37
Build 36112,111,707 - 2,113,056RGDNCBI36
Celera112,191,637 - 2,192,986RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,945,664 - 1,947,001UniSTS

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
SMAD4hsa-miR-483-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21112326
BBC3hsa-miR-483-3pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blot//Functional MTI20388800
GMNNhsa-miR-483-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCRNon-Functional MTI21305051
NHP2hsa-miR-483-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCRFunctional MTI21305051
PARD3hsa-miR-483-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI22101077
NUDChsa-miR-483-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
SOCS3hsa-miR-483-3pOncomiRDBexternal_infoNANA22052201
CTNNB1hsa-miR-483-3pOncomiRDBexternal_infoNANA21383185
SMAD4hsa-miR-483-3pOncomiRDBexternal_infoNANA21112326
BBC3hsa-miR-483-3pOncomiRDBexternal_infoNANA20388800
MAPK3hsa-miR-483-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI22465663
MAPK3hsa-miR-483-5pOncomiRDBexternal_infoNANA22465663

Predicted Targets
Summary Value
Count of predictions:27600
Count of gene targets:10911
Count of transcripts:21910
Interacting mature miRNAs:hsa-miR-483-3p, hsa-miR-483-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 11 1 25 24 24 1 4 8 8 22 9 1
Low 28 34 64 55 11 53 51 15 30 32 73 40 3 16 30 2
Below cutoff 12 19 16 9 10 6 25 36 16 3 8 14 4 6 21

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000385070
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl112,134,134 - 2,134,209 (-)Ensembl
RefSeq Acc Id: NR_030158
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,134,134 - 2,134,209 (-)NCBI
GRCh37112,155,364 - 2,155,439 (-)RGD
Celera112,191,870 - 2,191,945 (-)RGD
CHM1_1112,153,988 - 2,154,063 (-)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1975511-2888695)x3 copy number gain See cases [RCV000136112] Chr11:1975511..2888695 [GRCh38]
Chr11:1996741..2909925 [GRCh37]
Chr11:1953317..2866501 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:1975511-2138446)x3 copy number gain See cases [RCV000137018] Chr11:1975511..2138446 [GRCh38]
Chr11:1996741..2159676 [GRCh37]
Chr11:1953317..2116252 [NCBI36]
Chr11:11p15.5
benign
GRCh38/hg38 11p15.5-15.4(chr11:1537379-3360769)x3 copy number gain See cases [RCV000136847] Chr11:1537379..3360769 [GRCh38]
Chr11:1558609..3381999 [GRCh37]
Chr11:1515185..3338575 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1975511-3624139)x1 copy number loss See cases [RCV000137066] Chr11:1975511..3624139 [GRCh38]
Chr11:1996741..3645369 [GRCh37]
Chr11:1953317..3601945 [NCBI36]
Chr11:11p15.5-15.4
uncertain significance
GRCh38/hg38 11p15.5(chr11:2052381-2138446)x3 copy number gain See cases [RCV000137157] Chr11:2052381..2138446 [GRCh38]
Chr11:2073611..2159676 [GRCh37]
Chr11:2030187..2116252 [NCBI36]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:2127344-2159430)x3 copy number gain See cases [RCV000141243] Chr11:2127344..2159430 [GRCh38]
Chr11:2148574..2180660 [GRCh37]
Chr11:2105150..2137236 [NCBI36]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:1132899-3213923)x1 copy number loss See cases [RCV000142464] Chr11:1132899..3213923 [GRCh38]
Chr11:1126807..3235153 [GRCh37]
Chr11:1116807..3191729 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196855-5321874)x3 copy number gain See cases [RCV000142890] Chr11:196855..5321874 [GRCh38]
Chr11:196855..5343104 [GRCh37]
Chr11:186855..5299680 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:2106943-2565669)x3 copy number gain See cases [RCV000143587] Chr11:2106943..2565669 [GRCh38]
Chr11:2128173..2586899 [GRCh37]
Chr11:2084749..2543475 [NCBI36]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:196966-4435344)x3 copy number gain See cases [RCV000050927] Chr11:196966..4435344 [GRCh38]
Chr11:196966..4456574 [GRCh37]
Chr11:186966..4413150 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3377077)x3 copy number gain See cases [RCV000050947] Chr11:196966..3377077 [GRCh38]
Chr11:196966..3398307 [GRCh37]
Chr11:186966..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:218365-3377077)x3 copy number gain See cases [RCV000053614] Chr11:218365..3377077 [GRCh38]
Chr11:218365..3398307 [GRCh37]
Chr11:208365..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3624139)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|See cases [RCV000053592] Chr11:196966..3624139 [GRCh38]
Chr11:196966..3645369 [GRCh37]
Chr11:186966..3601945 [NCBI36]
Chr11:11p15.5-15.4
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32340 AgrOrtholog
COSMIC MIR483 COSMIC
Ensembl Genes ENSG00000207805 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000385070 ENTREZGENE
GTEx ENSG00000207805 GTEx
HGNC ID HGNC:32340 ENTREZGENE
Human Proteome Map MIR483 Human Proteome Map
miRBase MI0002467 ENTREZGENE
NCBI Gene 619552 ENTREZGENE
PharmGKB PA164722728 PharmGKB
RNAcentral URS000003575B RNACentral
  URS00000EA063 RNACentral
  URS000018B0EE RNACentral