Symbol:
MIR483
Name:
microRNA 483
RGD ID:
1604868
HGNC Page
HGNC:32340
Description:
Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Involved in several processes, including miRNA-mediated post-transcriptional gene silencing; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and negative regulation of intracellular signal transduction. Biomarker of colorectal cancer.
Type:
ncrna (Ensembl: miRNA)
RefSeq Status:
PROVISIONAL
Previously known as:
hsa-mir-483; mir-483; MIRN483
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 11 2,134,134 - 2,134,209 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 11 2,134,134 - 2,134,209 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 11 2,155,364 - 2,155,439 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 11 2,111,939 - 2,112,014 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 11 2,191,870 - 2,191,945 (-) NCBI Celera Cytogenetic Map 11 p15.5 NCBI CHM1_1 11 2,153,988 - 2,154,063 (-) NCBI CHM1_1 T2T-CHM13v2.0 11 2,221,787 - 2,221,862 (-) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
MIR483 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 11 2,134,134 - 2,134,209 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 11 2,134,134 - 2,134,209 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 11 2,155,364 - 2,155,439 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 11 2,111,939 - 2,112,014 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 11 2,191,870 - 2,191,945 (-) NCBI Celera Cytogenetic Map 11 p15.5 NCBI CHM1_1 11 2,153,988 - 2,154,063 (-) NCBI CHM1_1 T2T-CHM13v2.0 11 2,221,787 - 2,221,862 (-) NCBI T2T-CHM13v2.0
Mir483 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 142,208,661 - 142,208,733 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 142,208,661 - 142,208,733 (-) Ensembl GRCm39 Ensembl GRCm38 7 142,654,924 - 142,654,996 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 142,654,924 - 142,654,996 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 149,840,829 - 149,840,901 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 Celera 7 142,411,260 - 142,411,332 (-) NCBI Celera Cytogenetic Map 7 F5 NCBI cM Map 7 87.99 NCBI
.
Confirmed Targets
SMAD4 hsa-miR-483-3p Mirtarbase external_info Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 21112326 BBC3 hsa-miR-483-3p Mirtarbase external_info qRT-PCR//Luciferase reporter assay//Western blot// Functional MTI 20388800 GMNN hsa-miR-483-3p Mirtarbase external_info Luciferase reporter assay//qRT-PCR Non-Functional MTI 21305051 NHP2 hsa-miR-483-3p Mirtarbase external_info Luciferase reporter assay//qRT-PCR Functional MTI 21305051 PARD3 hsa-miR-483-3p Mirtarbase external_info qRT-PCR//Western blot Functional MTI 22101077 NUDC hsa-miR-483-3p Mirtarbase external_info CLASH Functional MTI (Weak) 23622248 SOCS3 hsa-miR-483-3p OncomiRDB external_info NA NA 22052201 CTNNB1 hsa-miR-483-3p OncomiRDB external_info NA NA 21383185 SMAD4 hsa-miR-483-3p OncomiRDB external_info NA NA 21112326 BBC3 hsa-miR-483-3p OncomiRDB external_info NA NA 20388800 MAPK3 hsa-miR-483-5p Mirtarbase external_info Luciferase reporter assay//Microarray//qRT-PCR//We Functional MTI 22465663 MAPK3 hsa-miR-483-5p OncomiRDB external_info NA NA 22465663
Predicted Targets
Count of predictions: 27600 Count of gene targets: 10911 Count of transcripts: 21910 Interacting mature miRNAs: hsa-miR-483-3p, hsa-miR-483-5p Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction
1558691 SCL8_H Serum cholesterol level QTL 8 (human) 1.2 Lipid level HDL cholesterol 11 1 5227071 Human
ECD00298
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,257 - 2,157,173 UniSTS GRCh37 Build 36 11 2,112,833 - 2,113,749 RGD NCBI36 Celera 11 2,192,763 - 2,193,680 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,946,778 - 1,947,694 UniSTS
ECD00602
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,340 - 2,156,238 UniSTS GRCh37 Build 36 11 2,111,916 - 2,112,814 RGD NCBI36 Celera 11 2,191,846 - 2,192,744 RGD Cytogenetic Map 11 p15.5 UniSTS
REN116999
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,070 - 2,155,294 UniSTS GRCh37 Build 36 11 2,111,646 - 2,111,870 RGD NCBI36 Celera 11 2,191,576 - 2,191,800 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,945,603 - 1,945,827 UniSTS
REN117000
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,365 - 2,155,599 UniSTS GRCh37 Build 36 11 2,111,941 - 2,112,175 RGD NCBI36 Celera 11 2,191,871 - 2,192,105 RGD Cytogenetic Map 11 p15.5 UniSTS
REN117001
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,575 - 2,155,819 UniSTS GRCh37 Build 36 11 2,112,151 - 2,112,395 RGD NCBI36 Celera 11 2,192,081 - 2,192,325 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,946,096 - 1,946,340 UniSTS
REN117002
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,803 - 2,156,039 UniSTS GRCh37 Build 36 11 2,112,379 - 2,112,615 RGD NCBI36 Celera 11 2,192,309 - 2,192,545 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,946,324 - 1,946,560 UniSTS
REN117003
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,016 - 2,156,265 UniSTS GRCh37 Build 36 11 2,112,592 - 2,112,841 RGD NCBI36 Celera 11 2,192,522 - 2,192,771 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,946,537 - 1,946,786 UniSTS
REN117004
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,288 - 2,156,516 UniSTS GRCh37 Build 36 11 2,112,864 - 2,113,092 RGD NCBI36 Celera 11 2,192,794 - 2,193,022 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,946,809 - 1,947,037 UniSTS
REN117005
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,495 - 2,156,735 UniSTS GRCh37 Build 36 11 2,113,071 - 2,113,311 RGD NCBI36 Celera 11 2,193,001 - 2,193,242 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,947,016 - 1,947,256 UniSTS
REN117006
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,716 - 2,156,973 UniSTS GRCh37 Build 36 11 2,113,292 - 2,113,549 RGD NCBI36 Celera 11 2,193,223 - 2,193,480 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,947,237 - 1,947,494 UniSTS
REN117007
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,156,964 - 2,157,232 UniSTS GRCh37 Build 36 11 2,113,540 - 2,113,808 RGD NCBI36 Celera 11 2,193,471 - 2,193,739 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,947,485 - 1,947,753 UniSTS
stSG548714
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,154,924 - 2,155,105 UniSTS GRCh37 Build 36 11 2,111,500 - 2,111,681 RGD NCBI36 Celera 11 2,191,430 - 2,191,611 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,945,457 - 1,945,638 UniSTS
stSG548715
Human Assembly Chr Position (strand) Source JBrowse GRCh37 11 2,155,131 - 2,156,480 UniSTS GRCh37 Build 36 11 2,111,707 - 2,113,056 RGD NCBI36 Celera 11 2,191,637 - 2,192,986 RGD Cytogenetic Map 11 p15.5 UniSTS HuRef 11 1,945,664 - 1,947,001 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
entire extraembryonic component
22
51
51
45
68
105
149
3
88
21
83
35
257
120
14
54
47
106
64
7
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000385070
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 11 2,134,134 - 2,134,209 (-) Ensembl
RefSeq Acc Id:
NR_030158
RefSeq Status:
PROVISIONAL
Type:
NON-CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 11 2,134,134 - 2,134,209 (-) NCBI GRCh37 11 2,155,364 - 2,155,439 (-) RGD Celera 11 2,191,870 - 2,191,945 (-) RGD CHM1_1 11 2,153,988 - 2,154,063 (-) NCBI T2T-CHM13v2.0 11 2,221,787 - 2,221,862 (-) NCBI
Sequence:
GAGGGGGAAGACGGGAGGAAAGAAGGGAGTGGTTCCATCACGCCTCCTCACTCCTCTCCTCCCGTCTTCTCCTCTC
hide sequence
