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Gene: SRI (sorcin) Homo sapiens
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Symbol: SRI
Name: sorcin
RGD ID: 1603229
Description: Exhibits several functions, including identical protein binding activity; protease binding activity; and protein heterodimerization activity. Involved in regulation of calcium ion transmembrane transporter activity; regulation of heart contraction; and regulation of relaxation of muscle. Localizes to several cellular components, including Z disc; endoplasmic reticulum membrane; and extracellular exosome. Colocalizes with chromaffin granule membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 22 kDa protein; calcium binding protein amplified in mutlidrug-resistant cells; CP-22; CP22; FLJ26259; H_RG167B05.1; SCN; V19
Orthologs:
Mus musculus (house mouse) : Sri (sorcin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sri (sorcin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sri (sorcin)
Pan paniscus (bonobo/pygmy chimpanzee) : SRI (sorcin)
Canis lupus familiaris (dog) : SRI (sorcin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sri (sorcin)
Sus scrofa (pig) : SRI (sorcin)
Chlorocebus sabaeus (African green monkey) : SRI (sorcin)
Heterocephalus glaber (naked mole-rat) : Sri (sorcin)
more info ...
Related Pseudogenes: SRIP1   SRIP2   SRIP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl788,205,115 - 88,226,993 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl788,205,118 - 88,226,993 (-)EnsemblGRCh38hg38GRCh38
GRCh38788,205,115 - 88,226,976 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37787,834,430 - 87,856,308 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36787,672,368 - 87,694,244 (-)NCBINCBI36hg18NCBI36
Celera782,539,034 - 82,560,910 (-)NCBI
Cytogenetic Map7q21.12NCBI
HuRef782,444,285 - 82,466,161 (-)NCBIHuRef
CHM1_1787,764,960 - 87,786,830 (-)NCBICHM1_1
CRA_TCAGchr7v2787,165,789 - 87,187,665 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SRI
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603229
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.