Sumo3 (small ubiquitin-like modifier 3)

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Gene: Sumo3 (small ubiquitin-like modifier 3) Rattus norvegicus

Analyze

Symbol:

Sumo3

Name:

small ubiquitin-like modifier 3

RGD ID:

1561022

Description:

Predicted to enable SUMO transferase activity; protein tag; and ubiquitin-like protein ligase binding activity. Predicted to be involved in negative regulation of DNA binding activity; protein sumoylation; and regulation of protein localization to nucleus. Predicted to act upstream of or within positive regulation of ubiquitin-dependent protein catabolic process and protein localization to nucleus. Predicted to be located in PML body. Predicted to be active in nucleus. Orthologous to human SUMO3 (small ubiquitin like modifier 3); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; ammonium chloride.

Type:

protein-coding (Ensembl: lncRNA)

RefSeq Status:

PROVISIONAL

Previously known as:

LOC499417; similar to Ubiquitin-like protein SMT3A precursor (Ubiquitin-related protein SUMO-2); small ubiquitin-related modifier 3; SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae); SUMO-3

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SUMO3 (small ubiquitin like modifier 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Sumo3 (small ubiquitin-like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sumo3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100970998 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SUMO3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sumo3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SUMO3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SUMO3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sumo3 (small ubiquitin like modifier 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SUMO2 (small ubiquitin like modifier 2)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	SUMO3 (small ubiquitin like modifier 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Sumo3 (small ubiquitin-like modifier 3)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	sumo3a (small ubiquitin-like modifier 3a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	sumo3b (small ubiquitin-like modifier 3b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SMT3	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	smt3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sumo3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	11,010,140 - 11,020,850 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	11,007,148 - 11,020,877 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	20	11,010,166 - 11,020,696 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	11,709,642 - 11,720,195 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	11,070,611 - 11,081,166 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	11,542,357 - 11,552,911 (-)	NCBI	Rnor_WKY
Rnor_6.0	20	11,726,488 - 11,737,050 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	11,726,497 - 11,737,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	13,892,796 - 13,903,349 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	11,393,957 - 11,404,510 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	12,514,863 - 12,525,416 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autoimmune polyendocrine syndrome type 1 (ISO)

cataract 9 multiple types (ISO)

developmental and epileptic encephalopathy 30 (ISO)

homocystinuria (ISO)

Neurodevelopmental Disorders (ISO)

primary ciliary dyskinesia (ISO)

progressive myoclonus epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

7,12-dimethyltetraphene (ISO)

acetylsalicylic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

buspirone (EXP)

C60 fullerene (EXP)

carbon nanotube (ISO)

cerium trichloride (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP,ISO)

dorsomorphin (ISO)

endosulfan (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

GW 4064 (ISO)

hinokiflavone (ISO)

hydralazine (ISO)

methyl methanesulfonate (ISO)

paracetamol (ISO)

phenobarbital (ISO)

rifampicin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulindac (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

trichostatin A (ISO)

triptonide (ISO)

tungsten (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of DNA binding (ISO)

positive regulation of ubiquitin-dependent protein catabolic process (ISO)

protein localization to nucleus (ISO)

protein sumoylation (IBA,ISO,ISS)

regulation of protein localization to nucleus (ISO)

Cellular Component

cytoplasm (IEA)

nuclear body (ISO)

nucleus (IBA,ISO)

PML body (ISO,ISS)

Molecular Function

protein binding (ISO)

protein tag (IBA)

SUMO transferase activity (ISO)

ubiquitin-like protein ligase binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA transport pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11889051	PMID:15489334	PMID:15767674	PMID:16626738	PMID:17696781	PMID:18167501	PMID:18538659	PMID:18644859	PMID:19050011	PMID:19275883	PMID:20075418	PMID:21330375
PMID:21518833	PMID:21965678	PMID:22082260	PMID:22891650	PMID:23376485	PMID:24105744	PMID:24971350

Genomics

Comparative Map Data

Sumo3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	11,010,140 - 11,020,850 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	11,007,148 - 11,020,877 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	20	11,010,166 - 11,020,696 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	11,709,642 - 11,720,195 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	11,070,611 - 11,081,166 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	11,542,357 - 11,552,911 (-)	NCBI	Rnor_WKY
Rnor_6.0	20	11,726,488 - 11,737,050 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	11,726,497 - 11,737,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	13,892,796 - 13,903,349 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	11,393,957 - 11,404,510 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	20	12,514,863 - 12,525,416 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

SUMO3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	44,805,617 - 44,818,062 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	21	44,805,617 - 44,818,779 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	46,225,532 - 46,237,977 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	45,049,960 - 45,062,472 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	45,049,959 - 45,062,472	NCBI
Celera	21	31,332,860 - 31,345,231 (-)	NCBI		Celera
Cytogenetic Map	21	q22.3	NCBI
HuRef	21	31,598,890 - 31,611,428 (-)	NCBI		HuRef
CHM1_1	21	45,786,069 - 45,798,882 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	21	43,165,885 - 43,178,512 (-)	NCBI		T2T-CHM13v2.0

Sumo3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	77,441,931 - 77,454,165 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	77,441,931 - 77,454,165 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	77,606,097 - 77,618,331 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	77,606,097 - 77,618,331 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	77,068,979 - 77,081,076 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	77,049,986 - 77,061,092 (+)	NCBI		MGSCv36	mm8
Celera	10	78,649,331 - 78,661,426 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Sumo3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	41,727,181 - 41,732,692 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	41,725,992 - 41,732,692 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100970998
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	742,770 - 744,488 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	224,215,377 - 224,217,052 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	229,701,496 - 229,703,222 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

SUMO3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	38,472,076 - 38,484,358 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	37,669,343 - 37,682,430 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	38,073,632 - 38,088,790 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	38,074,740 - 38,087,270 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	37,936,323 - 37,951,319 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	37,897,194 - 37,911,794 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	38,412,554 - 38,425,676 (-)	NCBI		UU_Cfam_GSD_1.0

Sumo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	37,718,057 - 37,729,250 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936778	1,392,110 - 1,412,153 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUMO3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	207,476,441 - 207,484,250 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	207,475,303 - 207,484,362 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	217,406,416 - 217,415,476 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SUMO3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	88,516,906 - 88,529,098 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	16,691,675 - 16,703,821 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sumo3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	30,385,940 - 30,393,326 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	30,384,762 - 30,393,454 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sumo3
66 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	146
Count of miRNA genes:	113
Interacting mature miRNAs:	131
Transcripts:	ENSRNOT00000001637
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	14101050	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	4606607	17617956	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	4606607	17617956	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	6691706	17489458	Rat
1581577	Pur15	Proteinuria QTL 15	4.38	0.0002	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	20	8042410	17617956	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
631265	Iresp1	Immunoglobin response QTL1	8.3		blood anti-double stranded DNA antibody amount (VT:0004762)	serum anti-DNA antibody level (CMO:0001533)	20	9039719	13461775	Rat

Markers in Region

RH142469

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	11,012,829 - 11,012,936 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	11,833,533 - 11,833,639	NCBI	Rnor6.0
Rnor_6.0	20	11,729,183 - 11,729,289	NCBI	Rnor6.0
Rnor_5.0	20	13,997,414 - 13,997,520	UniSTS	Rnor5.0
Rnor_5.0	20	13,895,482 - 13,895,588	UniSTS	Rnor5.0
RGSC_v3.4	20	11,396,643 - 11,396,749	UniSTS	RGSC3.4
Celera	20	12,517,549 - 12,517,655	UniSTS
RH 3.4 Map	20	153.96	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001842430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005497327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC108323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000001637 ⟹ ENSRNOP00000001637

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	11,010,166 - 11,020,696 (+)	Ensembl
Rnor_6.0 Ensembl	20	11,726,497 - 11,737,050 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094434

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	11,007,148 - 11,020,877 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094759

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	11,007,148 - 11,017,742 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000115542

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	11,007,220 - 11,013,658 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000118151

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	11,007,148 - 11,012,579 (-)	Ensembl

RefSeq Acc Id:

NM_001024295 ⟹ NP_001019466

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	11,010,144 - 11,020,697 (-)	NCBI
Rnor_6.0	20	11,726,497 - 11,737,050 (-)	NCBI
Rnor_5.0	20	13,892,796 - 13,903,349 (-)	NCBI
RGSC_v3.4	20	11,393,957 - 11,404,510 (-)	RGD
Celera	20	12,514,863 - 12,525,416 (-)	RGD

Sequence:

show sequence

GGGGCAGAGAGCGTGACTCGCCCGCTCCAGTGCCACCGGTTCCCGCTGCGCTTGCCGCCGCCGT
CGCCGCGCAACCATGTCGGAAGAGAAGCCCAAGGAGGGTGTGAAGACAGAGAACGACCACATCA
ACCTGAAAGTGGCAGGGCAGGATGGCTCAGTGGTGCAGTTCAAGATCAAGAGGCACACTCCGCT
GAGCAAGCTGATGAAGGCCTACTGTGAGAGGCAGGGCTTGTCAATGAGGCAGATTCGATTCCGG
TTTGATGGACAACCAATCAACGAAACAGACACTCCAGCCCAGCTGGAGATGGAGGATGAGGACA
CCATTGATGTATTCCAGCAGCAGACGGGAGGAACGGCCTCCCGAGCCAGCGTCCCCACACCCAG
CCATTTTCCTGACATTTGCTATTGAATGGTGACCATGCAGCCACACCAATCACACAAGAGTCCG
CAGAAGCCAGAGTCACCGAAAAGAGTCTCCTTTCCCGATGCGCTTGGAGTGAACTACATCCAGA
ATACGCTGCAGGGCGAGAGCATTACATACCCTGGTCGTTAGGAGGGTTTGGTTTGGGGGAAATG
AGGCGTGGGGTTTTTGGGGTTTGTTTTGTTTTCATTTGTTTCCTCCCATTTCTAAAATTTTTTT
CTCCCCCAAACTTGGGTCTGGATGTACAGACTCTCACCCTGTGGCCTGAGTCTAATCCCTAGAA
CTATGGTTTCCTCCGGTGTGACTTGTCCTGATCAGGTAGAGAGAGCTTGTGGTCACATTACCCA
GTGGGCATACCTGTGGGATGTGGGGAGGGGCAGAGAAGCAGAATTCCACCCGTTTGTTGTAGGC
ATAGGATATTAAAATGTGAAATACTGTAAATTTGAGCTTTGTCAAGCATATGGTGAAGTTAAGG
GAAAAAGACCAGTGCTTCTTAAAAACTGTGAGGAGTCTTCCTACTGTGGCCCAGGCCGGCATAT
GCCCACTTGCTTCTGGCATCTGGTAATGGATACATCGGTAAGGGTGGCATAGTGAAACCCACCC
CCCACCCTTTTTATAATGTCCAAGAAAGTAATTGTCCCGTCCCATTTGGAAATTGAACATGATC
TCAGATTCTTCTGGTCCTTGCTAGATATATAATTATGGTTTCTGTCTAAGAAGGTAATCAGTTA
AGTATCAAGTTTGCTGCAGTGTTGTGTAAGAGCCCCGCTTTCAAGTGTGGTTGCAAAAGCAAGC
CCAGGAAAGGTGACCTCATTTTCCCGGATTGTGGTGTGCAGTTTTCCAAGTGTGTGTTAACGGG
ACGCCTCGGTGGGTGACTGCGGTTCTGCATCGTGGGGTCAGTTAAATGTCTATAGTTCCTGCCT
GCCATCCTTCTGTAAGGATCCATTGCTGCTTGATGGCCATCTCTGCCTTTTATAGTCACCCGAC
ACTGACCTACCATCTCTCGCTTGCTTAAAGTCCCGAGGAAAATGTTTCTGCCTGTTTGCTGCGT
GGGCCTGGGTGGGGTGTCTGTCGGCTCTGTTGTGTTTCTTCACCGGTTTGTACCTGTTGTCCTT
TACTACTGTAAACAGTAAATATAGTTTGGTATTCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_005497327

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	11,010,140 - 11,020,850 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001019466	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83728	(Get FASTA)	NCBI Sequence Viewer
	EDL97095	(Get FASTA)	NCBI Sequence Viewer
	EDL97096	(Get FASTA)	NCBI Sequence Viewer
	EDL97097	(Get FASTA)	NCBI Sequence Viewer
	EDL97098	(Get FASTA)	NCBI Sequence Viewer
	Q5XIF4	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001019466 ⟸ NM_001024295
- UniProtKB:	Q5XIF4 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQ PINETDTPAQLEMEDEDTIDVFQQQTGGTASRASVPTPSHFPDICY hide sequence

RefSeq Acc Id:

ENSRNOP00000001637 ⟸ ENSRNOT00000001637

Protein Domains

Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIF4-F1-model_v2	AlphaFold	Q5XIF4	1-110	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701503

Promoter ID:

EPDNEW_R12027

Type:

initiation region

Name:

Sumo3_1

Description:

small ubiquitin-like modifier 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	11,737,070 - 11,737,130	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561022	AgrOrtholog
BioCyc Gene	G2FUF-4241	BioCyc
Ensembl Genes	ENSRNOG00000038489	Ensembl
	ENSRNOG00000064656	Ensembl
IMAGE_CLONE	IMAGE:7191303	IMAGE-MGC_LOAD
InterPro	Rad60/SUMO-like_dom	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
	Ubiquitin_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:499417	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94630	IMAGE-MGC_LOAD
NCBI Gene	499417	ENTREZGENE
PANTHER	SMALL UBIQUITIN-RELATED MODIFIER	UniProtKB/Swiss-Prot
	SMALL UBIQUITIN-RELATED MODIFIER 3-RELATED	UniProtKB/Swiss-Prot
Pfam	Rad60-SLD	UniProtKB/Swiss-Prot
PhenoGen	Sumo3	PhenoGen
PROSITE	UBIQUITIN_2	UniProtKB/Swiss-Prot
SMART	UBQ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54236	UniProtKB/Swiss-Prot
UniProt	Q5XIF4	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Sumo3	small ubiquitin-like modifier 3	Sumo3	small ubiquitin-like modifier 3	Data Merged	737654	PROVISIONAL
2021-08-09	Sumo3	small ubiquitin-like modifier 3			Symbol and Name status set to provisional	45752	PROVISIONAL
2013-06-14	Sumo3	small ubiquitin-like modifier 3	Sumo3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Sumo3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	LOC499417	similar to Ubiquitin-like protein SMT3A precursor (Ubiquitin-related protein SUMO-2)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC499417	similar to Ubiquitin-like protein SMT3A precursor (Ubiquitin-related protein SUMO-2)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)