Megf10 (multiple EGF-like-domains 10) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Megf10 (multiple EGF-like-domains 10) Mus musculus
Analyze
Symbol: Megf10
Name: multiple EGF-like-domains 10
RGD ID: 1558549
MGI Page MGI
Description: Enables Notch binding activity. Involved in several processes, including myoblast development; positive regulation of myoblast proliferation; and skeletal muscle satellite cell proliferation. Acts upstream of or within apoptotic process involved in development; engulfment of apoptotic cell; and recognition of apoptotic cell. Located in phagocytic cup. Is expressed in several structures, including brain; heart; retina layer; skeletal muscle tissue; and testis. Human ortholog(s) of this gene implicated in congenital myopathy 10B and early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3000002B06Rik; gene model 331, (NCBI); Gm331; multiple EGF-like domains protein 10; multiple epidermal growth factor-like domains protein 10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391857,266,162 - 57,430,539 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1857,266,162 - 57,430,539 (+)EnsemblGRCm39 Ensembl
GRCm381857,133,090 - 57,297,467 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv371857,292,744 - 57,457,121 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361857,258,844 - 57,422,835 (+)NCBIMGSCv36mm8
Celera1858,443,454 - 58,608,465 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1831.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10Mousecongenital myopathy 10B  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital myopathy 10b and mild variantClinVarPMID:22101682 more ...
Megf10Mouseearly-onset myopathy-areflexia-respiratory distress-dysphagia syndrome  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: MEGF10-related myopathyClinVarPMID:16199547 more ...
Megf10Mousefamilial adenomatous polyposis 1  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial adenomatous polyposis 1ClinVarPMID:17963004 more ...
Megf10Mousegenetic disease  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Megf10MouseHereditary Neoplastic Syndromes  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary Cancer SyndromeClinVarPMID:17963004 more ...
Megf10MouseNeurodevelopmental Disorders  ISOMEGF10 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10MouseDeglutition Disorders  ISOMEGF10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22101682
Megf10Mousemuscular disease  ISOMEGF10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22101682
Megf10Mousenewborn respiratory distress syndrome  ISOMEGF10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22101682
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10Mousecongenital myopathy 10B  ISOMEGF10 (Homo sapiens)7240710 OMIM 
Megf10Mouseearly-onset myopathy-areflexia-respiratory distress-dysphagia syndrome  ISOMEGF10 (Homo sapiens)7240710 OMIM 

1 to 20 of 63 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10Mouse17beta-estradiol multiple interactionsISOMEGF10 (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in increased expression of MEGF10 mRNACTDPMID:20660070
Megf10Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MEGF10 mRNACTDPMID:19933214
Megf10Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionISOMegf10 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of MEGF10 mRNACTDPMID:32109520 and PMID:33387578
Megf10Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of MEGF10 mRNACTDPMID:21570461
Megf10Mouse4,4'-sulfonyldiphenol increases methylationEXP 6480464bisphenol S results in increased methylation of MEGF10 exonCTDPMID:33297965
Megf10Mouse4,4'-sulfonyldiphenol affects methylationEXP 6480464bisphenol S affects the methylation of MEGF10 geneCTDPMID:31683443
Megf10Mouse6-propyl-2-thiouracil decreases expressionISOMegf10 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of MEGF10 mRNACTDPMID:36843608
Megf10Mouseacrylamide decreases expressionISOMEGF10 (Homo sapiens)6480464Acrylamide results in decreased expression of MEGF10 mRNACTDPMID:32763439
Megf10Mouseaflatoxin B1 decreases methylationISOMEGF10 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of MEGF10 geneCTDPMID:27153756
Megf10Mouseall-trans-retinoic acid increases expressionISOMEGF10 (Homo sapiens)6480464Tretinoin results in increased expression of MEGF10 mRNACTDPMID:21934132
Megf10Mouseammonium chloride affects expressionISOMegf10 (Rattus norvegicus)6480464Ammonium Chloride affects the expression of MEGF10 mRNACTDPMID:16483693
Megf10Mouseatrazine increases expressionISOMEGF10 (Homo sapiens)6480464Atrazine results in increased expression of MEGF10 mRNACTDPMID:22378314
Megf10Mouseatrazine affects methylationISOMegf10 (Rattus norvegicus)6480464Atrazine affects the methylation of MEGF10 geneCTDPMID:28931070 and PMID:35440735
Megf10Mousebenzo[a]pyrene affects methylationISOMEGF10 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of MEGF10 5' UTR and Benzo(a)pyrene affects the methylation of MEGF10 promoterCTDPMID:27901495
Megf10Mousebenzo[a]pyrene increases methylationISOMEGF10 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of MEGF10 3' UTRCTDPMID:27901495
Megf10Mousebisphenol A decreases expressionISOMegf10 (Rattus norvegicus)6480464bisphenol A results in decreased expression of MEGF10 mRNACTDPMID:25181051
Megf10Mousebisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of MEGF10 mRNACTDPMID:35479511
Megf10Mousebisphenol A multiple interactionsISOMEGF10 (Homo sapiens)6480464[bisphenol A co-treated with Fulvestrant] results in increased methylation of MEGF10 geneCTDPMID:31601247
Megf10Mousebisphenol A increases methylationISOMegf10 (Rattus norvegicus)6480464bisphenol A results in increased methylation of MEGF10 geneCTDPMID:28505145
Megf10Mousecarbamazepine affects expressionISOMEGF10 (Homo sapiens)6480464Carbamazepine affects the expression of MEGF10 mRNACTDPMID:25979313

1 to 20 of 63 rows

Biological Process
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10Mouseapoptotic cell clearance involved_inIBAPANTHER:PTN002778616 and MGI:26851772290270 GO_CentralGO_REF:0000033
Megf10Mouseapoptotic process involved in development acts_upstream_of_or_withinIMPMGI:44541902290270 PMID:27170117MGIPMID:27170117
Megf10Mouseengulfment of apoptotic cell acts_upstream_of_or_withinIMPMGI:44541902290270 PMID:27170117MGIPMID:27170117
Megf10Mousehomotypic cell-cell adhesion involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousehomotypic cell-cell adhesion involved_inISSUniProtKB:Q96KG72290270 UniProtGO_REF:0000024
Megf10Mousemuscle cell development involved_inISSUniProtKB:Q96KG72290270 UniProtGO_REF:0000024
Megf10Mousemuscle cell development involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousemuscle cell proliferation involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousemyoblast development involved_inIMP 2290270 PMID:31267131UniProtPMID:31267131
Megf10Mousemyoblast migration involved_inIMP 2290270 PMID:28498977UniProtPMID:28498977
Megf10Mousemyoblast migration involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousepositive regulation of cell-cell adhesion involved_inIEAUniProtKB:Q96KG7 and ensembl:ENSP000004233542290270 EnsemblGO_REF:0000107
Megf10Mousepositive regulation of cell-cell adhesion involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousepositive regulation of myoblast proliferation involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousepositive regulation of myoblast proliferation involved_inIMP 2290270 PMID:31267131UniProtPMID:31267131
Megf10Mouserecognition of apoptotic cell acts_upstream_of_or_withinIDA 2290270 PMID:19915564MGIPMID:19915564
Megf10Mouserecognition of apoptotic cell acts_upstream_of_or_withinIMP 2290270 PMID:19915564MGIPMID:19915564
Megf10Mouseregulation of muscle cell differentiation involved_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mouseregulation of muscle cell differentiation involved_inISSUniProtKB:Q96KG72290270 UniProtGO_REF:0000024
Megf10Mouseregulation of skeletal muscle tissue development involved_inIEAUniProtKB:Q96KG7 and ensembl:ENSP000004233542290270 EnsemblGO_REF:0000107
1 to 20 of 25 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Megf10Mousecell projection located_inIEAUniProtKB-KW:KW-09662290270 UniProtGO_REF:0000043
Megf10Mousephagocytic cup located_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mousephagocytic cup located_inIDA 2290270 PMID:19915564MGIPMID:19915564
Megf10Mouseplasma membrane located_inISOUniProtKB:Q96KG72290270 GO_CentralGO_REF:0000119
Megf10Mouseplasma membrane located_inIDA 2290270 PMID:17643423 and PMID:28498977UniProtPMID:17643423 and PMID:28498977

Molecular Function

  


#
Reference Title
Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12904583   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17643423   PMID:18056409   PMID:19915564   PMID:21267068  
PMID:21873635   PMID:22407321   PMID:22993420   PMID:23954233   PMID:24154525   PMID:24270812   PMID:27170117   PMID:28498977   PMID:28526325   PMID:29611808   PMID:30802937   PMID:31267131  
PMID:31812516   PMID:31847788   PMID:32027825   PMID:32325033   PMID:33159715   PMID:33361813   PMID:33706013   PMID:34321999   PMID:34836962   PMID:37081759   PMID:37527657   PMID:38014224  
PMID:38760872   PMID:39133615  



Megf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391857,266,162 - 57,430,539 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1857,266,162 - 57,430,539 (+)EnsemblGRCm39 Ensembl
GRCm381857,133,090 - 57,297,467 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv371857,292,744 - 57,457,121 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361857,258,844 - 57,422,835 (+)NCBIMGSCv36mm8
Celera1858,443,454 - 58,608,465 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1831.5NCBI
MEGF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385127,229,300 - 127,461,222 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5127,290,796 - 127,465,737 (+)EnsemblGRCh38hg38GRCh38
GRCh375126,626,488 - 126,796,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365126,654,514 - 126,824,807 (+)NCBINCBI36Build 36hg18NCBI36
Celera5122,757,239 - 122,927,674 (+)NCBICelera
Cytogenetic Map5q23.2NCBI
HuRef5121,817,526 - 121,988,151 (+)NCBIHuRef
CHM1_15126,059,059 - 126,229,496 (+)NCBICHM1_1
T2T-CHM13v2.05127,749,142 - 127,981,009 (+)NCBIT2T-CHM13v2.0
Megf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,803,292 - 52,953,431 (+)NCBIGRCr8
mRatBN7.21850,605,231 - 50,755,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1850,605,656 - 50,754,456 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1852,694,133 - 52,797,033 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01853,409,354 - 53,512,382 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01851,200,013 - 51,302,914 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01852,215,652 - 52,366,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1852,215,682 - 52,366,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01851,403,811 - 51,554,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,948,935 - 53,051,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11853,052,380 - 53,072,113 (+)NCBI
Celera1848,786,696 - 48,889,249 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Megf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955415335,012 - 513,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955415393,642 - 513,157 (+)NCBIChiLan1.0ChiLan1.0
MEGF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24122,534,832 - 122,770,730 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15120,674,719 - 120,910,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05122,639,155 - 122,877,324 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15128,466,095 - 128,657,845 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5128,466,095 - 128,641,043 (+)Ensemblpanpan1.1panPan2
MEGF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,359,648 - 16,574,882 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,378,669 - 16,617,335 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1115,047,444 - 15,360,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,981,258 - 17,301,745 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,940,314 - 17,349,743 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11115,711,146 - 16,024,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01115,557,940 - 15,871,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01116,155,094 - 16,474,941 (+)NCBIUU_Cfam_GSD_1.0
Megf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213139,012,245 - 139,182,163 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936504586,190 - 756,255 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936504634,167 - 753,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEGF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2130,189,556 - 130,401,077 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12130,226,222 - 130,403,960 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22135,524,848 - 135,686,689 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEGF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12330,028,154 - 30,405,033 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2330,234,489 - 30,404,996 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603447,643,480 - 48,026,869 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Megf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477414,153,687 - 14,355,406 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477414,147,412 - 14,354,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Megf10
6792 total Variants

Predicted Target Of
Summary Value
Count of predictions:874
Count of miRNA genes:571
Interacting mature miRNAs:650
Transcripts:ENSMUST00000075770, ENSMUST00000139892
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 43 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185166830085668468Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185105215685052311Mouse
10412184Sstapa1_mSuseptibility to Staphylococus aureus infection 1 (mouse)Not determined184654154657590708Mouse
4141431Msmr2_mMSM lymphoma resistance 2 (mouse)Not determined5497587361238870Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182724111558827077Mouse
10412183Sstapa2_mSuseptibility to Staphylococus aureus infection 2 (mouse)Not determined185679463066952485Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185166830085668468Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse

1 to 10 of 43 rows






Ensembl Acc Id: ENSMUST00000075770   ⟹   ENSMUSP00000075174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1857,266,162 - 57,430,539 (+)Ensembl
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139892   ⟹   ENSMUSP00000116814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1857,275,858 - 57,425,800 (+)Ensembl
GRCm38.p6 Ensembl1857,142,786 - 57,292,728 (+)Ensembl
RefSeq Acc Id: NM_001001979   ⟹   NP_001001979
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391857,266,162 - 57,430,539 (+)NCBI
GRCm381857,133,090 - 57,297,467 (+)ENTREZGENE
MGSCv371857,292,744 - 57,457,121 (+)RGD
Celera1858,443,454 - 58,608,465 (+)RGD
cM Map18 ENTREZGENE
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001001979 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH75647 (Get FASTA)   NCBI Sequence Viewer  
  BAE27788 (Get FASTA)   NCBI Sequence Viewer  
  BAE28336 (Get FASTA)   NCBI Sequence Viewer  
  BAE38699 (Get FASTA)   NCBI Sequence Viewer  
  EDL09867 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000075174
  ENSMUSP00000075174.7
GenBank Protein Q6DIB5 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_001001979   ⟸   NM_001001979
- Peptide Label: precursor
- UniProtKB: Q6DIB5 (UniProtKB/Swiss-Prot),   Q3UG73 (UniProtKB/Swiss-Prot),   Q3TLU3 (UniProtKB/Swiss-Prot),   A0A140T8S0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000116814   ⟸   ENSMUST00000139892
Ensembl Acc Id: ENSMUSP00000075174   ⟸   ENSMUST00000075770
EGF-like   EMI

Name Modeler Protein Id AA Range Protein Structure
AF-Q6DIB5-F1-model_v2 AlphaFold Q6DIB5 1-1147 view protein structure

RGD ID:13677842
Promoter ID:EPDNEW_M23070
Type:initiation region
Name:Megf10_2
Description:Mus musculus multiple EGF-like-domains 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23071  EPDNEW_M23072  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381857,133,005 - 57,133,065EPDNEW
RGD ID:13677844
Promoter ID:EPDNEW_M23071
Type:initiation region
Name:Megf10_3
Description:Mus musculus multiple EGF-like-domains 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23070  EPDNEW_M23072  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381857,142,790 - 57,142,850EPDNEW
RGD ID:13677846
Promoter ID:EPDNEW_M23072
Type:single initiation site
Name:Megf10_1
Description:Mus musculus multiple EGF-like-domains 10 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23070  EPDNEW_M23071  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381857,159,339 - 57,159,399EPDNEW
RGD ID:6829364
Promoter ID:MM_KWN:25345
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:ENSMUST00000115370,   NM_001001979
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361857,292,391 - 57,292,891 (+)MPROMDB


1 to 33 of 33 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000024593 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000075770 ENTREZGENE
  ENSMUST00000075770.13 UniProtKB/Swiss-Prot
Gene3D-CATH Tie2 ligand-binding domain superfamily UniProtKB/Swiss-Prot
InterPro EGF-like_CS UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF_extracell UniProtKB/Swiss-Prot
  EMI_domain UniProtKB/Swiss-Prot
  Laminin_EGF UniProtKB/Swiss-Prot
  MEGF_diff_regulators UniProtKB/Swiss-Prot
KEGG Report mmu:70417 UniProtKB/Swiss-Prot
MGD MGI:2685177 ENTREZGENE
NCBI Gene Megf10 ENTREZGENE
PANTHER DELTA-RELATED UniProtKB/Swiss-Prot
  NIMROD A, ISOFORM E UniProtKB/Swiss-Prot
Pfam EGF_2 UniProtKB/Swiss-Prot
  hEGF UniProtKB/Swiss-Prot
  Laminin_EGF UniProtKB/Swiss-Prot
PhenoGen Megf10 PhenoGen
PRINTS EGFLAMININ UniProtKB/Swiss-Prot
PROSITE EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EMI UniProtKB/Swiss-Prot
SMART EGF UniProtKB/Swiss-Prot
  EGF_Lam UniProtKB/Swiss-Prot
UniProt A0A140T8S0 ENTREZGENE, UniProtKB/TrEMBL
  MEG10_MOUSE UniProtKB/Swiss-Prot
  Q3TLU3 ENTREZGENE
  Q3UG73 ENTREZGENE
  Q6DIB5 ENTREZGENE
UniProt Secondary Q3TLU3 UniProtKB/Swiss-Prot
  Q3UG73 UniProtKB/Swiss-Prot
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Megf10  multiple EGF-like-domains 10  Gm331  gene model 331, (NCBI)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Gm331  gene model 331, (NCBI)  Megf10  multiple EGF-like-domains 10  Symbol and/or name change 5135510 APPROVED