Gpihbp1 (GPI-anchored HDL-binding protein 1) - Rat Genome Database

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Gene: Gpihbp1 (GPI-anchored HDL-binding protein 1) Mus musculus
Analyze
Symbol: Gpihbp1
Name: GPI-anchored HDL-binding protein 1
RGD ID: 1557418
MGI Page MGI
Description: Enables lipase binding activity; lipoprotein particle binding activity; and protein transporter activity. Involved in several processes, including cholesterol homeostasis; positive regulation of chylomicron remnant clearance; and protein transport. Acts upstream of or within lipid transport. Located in apical plasma membrane; basolateral plasma membrane; and external side of plasma membrane. Is expressed in lung vascular element. Human ortholog(s) of this gene implicated in familial GPIHBP1 deficiency. Orthologous to human GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110002J19Rik; glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GPI-H; GPI-HBP1; high density lipoprotein-binding protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,468,479 - 75,470,062 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,468,477 - 75,471,330 (+)EnsemblGRCm39 Ensembl
GRCm381575,596,630 - 75,598,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,596,628 - 75,599,481 (+)EnsemblGRCm38mm10GRCm38
MGSCv371575,427,088 - 75,428,643 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,423,913 - 75,425,468 (+)NCBIMGSCv36mm8
Celera1577,096,812 - 77,098,367 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gpihbp1MouseBrown-Vialetto-Van Laere syndrome 2  ISOGPIHBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Brown-Vialetto-van Laere syndrome 2ClinVarPMID:20301336 more ...
Gpihbp1Mouseepidermolysis bullosa simplex with muscular dystrophy  ISOGPIHBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Epidermolysis bullosa simplex 5B and with muscular dystrophyClinVarPMID:20301336 more ...
Gpihbp1Mousefamilial GPIHBP1 deficiency  ISOGPIHBP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Gpihbp1Mousefamilial lipoprotein lipase deficiency  ISOGPIHBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hyperlipoproteinemia and type IClinVarPMID:20124439 more ...
Gpihbp1Mouseholoprosencephaly  ISOGPIHBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Holoprosencephaly sequenceClinVarPMID:28492532
Gpihbp1MouseRecombinant Chromosome 8 Syndrome  ISOGPIHBP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Recombinant 8 syndromeClinVarPMID:31690835
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gpihbp1Mousefamilial GPIHBP1 deficiency  ISOGPIHBP1 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gpihbp1Mouse(1->4)-beta-D-glucan multiple interactionsEXP 6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GPIHBP1 mRNACTDPMID:36331819
Gpihbp1Mouse1,1-dichloroethene increases expressionEXP 6480464vinylidene chloride results in increased expression of GPIHBP1 mRNACTDPMID:26682919
Gpihbp1Mouse1,2-dimethylhydrazine decreases expressionEXP 64804641 and 2-Dimethylhydrazine results in decreased expression of GPIHBP1 mRNACTDPMID:22206623
Gpihbp1Mouse2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28433925
Gpihbp1Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GPIHBP1 mRNACTDPMID:21570461
Gpihbp1Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGpihbp1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin affects the expression of GPIHBP1 mRNACTDPMID:34747641
Gpihbp1Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGpihbp1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of GPIHBP1 mRNACTDPMID:32109520
Gpihbp1Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GPIHBP1 mRNACTDPMID:28238261
Gpihbp1Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28433925
Gpihbp1Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of GPIHBP1 mRNACTDPMID:30951980 and PMID:39298647
Gpihbp1Mouse4,4'-sulfonyldiphenol decreases methylationEXP 6480464bisphenol S results in decreased methylation of GPIHBP1 geneCTDPMID:31683443
Gpihbp1Mouse6-propyl-2-thiouracil decreases expressionISOGpihbp1 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of GPIHBP1 mRNACTDPMID:25825206
Gpihbp1Mouse6-propyl-2-thiouracil increases expressionISOGpihbp1 (Rattus norvegicus)6480464Propylthiouracil results in increased expression of GPIHBP1 mRNACTDPMID:30047161
Gpihbp1Mousealpha-Zearalanol multiple interactionsISOGpihbp1 (Rattus norvegicus)6480464[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of GPIHBP1 mRNACTDPMID:35163327
Gpihbp1Mouseamitrole increases expressionISOGpihbp1 (Rattus norvegicus)6480464Amitrole results in increased expression of GPIHBP1 mRNACTDPMID:30047161
Gpihbp1Mouseamphetamine increases expressionISOGpihbp1 (Rattus norvegicus)6480464Amphetamine results in increased expression of GPIHBP1 mRNACTDPMID:30779732
Gpihbp1Mouseantirheumatic drug increases expressionISOGPIHBP1 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of GPIHBP1 mRNACTDPMID:24449571
Gpihbp1Mousebenzo[a]pyrene increases expressionEXP 6480464Benzo(a)pyrene results in increased expression of GPIHBP1 mRNACTDPMID:21964900
Gpihbp1Mousebenzo[a]pyrene decreases methylationISOGPIHBP1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of GPIHBP1 3' UTRCTDPMID:27901495
Gpihbp1Mousebenzo[a]pyrene affects methylationISOGPIHBP1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of GPIHBP1 promoterCTDPMID:27901495

1 to 20 of 67 rows

Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gpihbp1Mousecholesterol homeostasis involved_inIMP 2290270 PMID:17403372BHF-UCLPMID:17403372
Gpihbp1Mousecholesterol transport NOT|acts_upstream_of_or_withinIDA 2290270 PMID:12496272MGIPMID:12496272
Gpihbp1Mouseintracellular protein transport involved_inIDA 2290270 PMID:20620994BHF-UCLPMID:20620994
Gpihbp1Mouselipid transport acts_upstream_of_or_withinIDA 2290270 PMID:12496272MGIPMID:12496272
Gpihbp1Mousepositive regulation of chylomicron remnant clearance involved_inIMP 2290270 PMID:17403372BHF-UCLPMID:17403372
Gpihbp1Mousepositive regulation of chylomicron remodeling involved_inICGO:00510062290270 PMID:17403372BHF-UCLPMID:17403372
Gpihbp1Mousepositive regulation of fatty acid biosynthetic process involved_inISOGPIHBP1 (Homo sapiens)9068941 PMID:29899144ARUK-UCLPMID:29899144
Gpihbp1Mousepositive regulation of lipoprotein lipase activity involved_inIDA 2290270 PMID:19542565BHF-UCLPMID:19542565
Gpihbp1Mousepositive regulation of lipoprotein lipase activity involved_inISOUniProtKB:Q8IV162290270 GO_CentralGO_REF:0000119
Gpihbp1Mousepositive regulation of lipoprotein lipase activity involved_inIMP 2290270 PMID:17403372BHF-UCLPMID:17403372
Gpihbp1Mouseprotein import involved_inIDA 2290270 PMID:20620994BHF-UCLPMID:20620994
Gpihbp1Mouseprotein localization to cell surface involved_inIDA 2290270 PMID:20620994BHF-UCLPMID:20620994
Gpihbp1Mouseprotein stabilization involved_inISOUniProtKB:Q8IV162290270 GO_CentralGO_REF:0000119
Gpihbp1Mouseprotein stabilization involved_inIDA 2290270 PMID:19542565BHF-UCLPMID:19542565
Gpihbp1Mouseresponse to heparin involved_inISOUniProtKB:Q8IV162290270 GO_CentralGO_REF:0000119
Gpihbp1Mousetranscytosis involved_inIDA 2290270 PMID:20620994BHF-UCLPMID:20620994
Gpihbp1Mousetriglyceride catabolic process involved_inISOUniProtKB:Q8IV162290270 GO_CentralGO_REF:0000119
Gpihbp1Mousetriglyceride homeostasis involved_inIBAPANTHER:PTN001445799 more ...2290270 GO_CentralGO_REF:0000033
Gpihbp1Mousetriglyceride homeostasis involved_inISOUniProtKB:Q8IV162290270 GO_CentralGO_REF:0000119
Gpihbp1Mousetriglyceride homeostasis involved_inIMP 2290270 PMID:17403372BHF-UCLPMID:17403372
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Cellular Component

  

Molecular Function
1 to 14 of 14 rows

  
1 to 14 of 14 rows


#
Reference Title
Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12496272   PMID:16141072   PMID:16141073   PMID:17403372   PMID:18340083   PMID:18713736   PMID:18787041  
PMID:18845532   PMID:19141870   PMID:19542565   PMID:19726683   PMID:19815815   PMID:20204375   PMID:20562862   PMID:20617182   PMID:20620994   PMID:20814015   PMID:20889497   PMID:20966404  
PMID:21518912   PMID:21873635   PMID:22173228   PMID:23008484   PMID:23176178   PMID:23186339   PMID:24726386   PMID:25143463   PMID:25873395   PMID:26160324   PMID:26970521   PMID:27098205  
PMID:27138650   PMID:27811232   PMID:27984852   PMID:28476858   PMID:28694296   PMID:28752045   PMID:29031715   PMID:29449313   PMID:29719224   PMID:29739862   PMID:29899144   PMID:30224066  
PMID:30408040   PMID:30598475   PMID:30721842   PMID:31169500   PMID:31570698   PMID:32029511   PMID:32051149   PMID:32132144   PMID:33057196   PMID:35229724   PMID:36239312   PMID:37172802  
PMID:37824203   PMID:37974401  



Gpihbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,468,479 - 75,470,062 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,468,477 - 75,471,330 (+)EnsemblGRCm39 Ensembl
GRCm381575,596,630 - 75,598,213 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,596,628 - 75,599,481 (+)EnsemblGRCm38mm10GRCm38
MGSCv371575,427,088 - 75,428,643 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,423,913 - 75,425,468 (+)NCBIMGSCv36mm8
Celera1577,096,812 - 77,098,367 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1534.59NCBI
GPIHBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,213,218 - 143,217,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,213,218 - 143,217,170 (+)EnsemblGRCh38hg38GRCh38
GRCh378144,295,093 - 144,299,044 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,366,443 - 144,370,418 (+)NCBINCBI36Build 36hg18NCBI36
Celera8140,603,655 - 140,607,614 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,547,646 - 139,551,566 (+)NCBIHuRef
CHM1_18144,335,309 - 144,339,286 (+)NCBICHM1_1
T2T-CHM13v2.08144,358,507 - 144,362,402 (+)NCBIT2T-CHM13v2.0
Gpihbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,166,334 - 109,169,448 (+)NCBIGRCr8
mRatBN7.27107,285,584 - 107,288,702 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,285,654 - 107,288,702 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,020,613 - 109,023,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,244,277 - 111,247,324 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,190,206 - 111,193,253 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,632,496 - 116,635,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,632,506 - 116,634,293 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,525,703 - 116,528,750 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,538,424 - 113,541,471 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7103,648,499 - 103,651,546 (+)NCBICelera
Cytogenetic Map7q34NCBI
Gpihbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554541,970,626 - 1,973,743 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554541,965,627 - 1,972,479 (+)NCBIChiLan1.0ChiLan1.0
GPIHBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27160,690,170 - 160,694,121 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,207,643 - 136,211,594 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08139,960,255 - 139,964,189 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18142,980,151 - 142,984,629 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8142,980,151 - 142,985,429 (+)Ensemblpanpan1.1panPan2
GPIHBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,005,499 - 37,007,214 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,005,512 - 37,007,074 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1336,958,242 - 36,959,971 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,477,245 - 37,478,977 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,477,270 - 37,478,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,149,764 - 37,151,494 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,268,265 - 37,270,004 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,745,112 - 37,746,841 (+)NCBIUU_Cfam_GSD_1.0
Gpihbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,371,996 - 1,375,593 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364708,798,095 - 8,800,176 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPIHBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl41,254,565 - 1,256,577 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.141,253,401 - 1,256,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.241,344,593 - 1,347,007 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPIHBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,433,669 - 137,440,681 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,436,997 - 137,440,909 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,499,974 - 2,506,432 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpihbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473513,484,772 - 13,491,570 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473513,486,368 - 13,492,668 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gpihbp1
72 total Variants

1 to 10 of 91 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 8q24.21-24.3(chr8:128220912-145049449)x3 copy number gain See cases [RCV000050830] Chr8:128220912..145049449 [GRCh38]
Chr8:129233158..146274835 [GRCh37]
Chr8:129302340..146245639 [NCBI36]
Chr8:8q24.21-24.3
pathogenic
GRCh38/hg38 8q24.21-24.22(chr8:129176782-134170188)x1 copy number loss See cases [RCV000050751] Chr8:129176782..134170188 [GRCh38]
Chr8:130189028..135182431 [GRCh37]
Chr8:130258210..135251613 [NCBI36]
Chr8:8q24.21-24.22
pathogenic
GRCh38/hg38 8q23.3-24.3(chr8:113580402-145054634)x3 copy number gain See cases [RCV000050638] Chr8:113580402..145054634 [GRCh38]
Chr8:114592631..146280020 [GRCh37]
Chr8:114661807..146250824 [NCBI36]
Chr8:8q23.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000053678] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q24.21-24.23(chr8:126626164-137169427)x1 copy number loss See cases [RCV000054306] Chr8:126626164..137169427 [GRCh38]
Chr8:127638409..138181670 [GRCh37]
Chr8:127707591..138250852 [NCBI36]
Chr8:8q24.21-24.23
pathogenic
GRCh37/hg19 8q13.2-24.3(chr8:68912432-146295771)x2 copy number gain See cases [RCV002292707] Chr8:68912432..146295771 [GRCh37]
Chr8:8q13.2-24.3
pathogenic
GRCh38/hg38 8q24.21-24.3(chr8:130115518-141228210)x3 copy number gain See cases [RCV000133621] Chr8:130115518..141228210 [GRCh38]
Chr8:131127764..142238309 [GRCh37]
Chr8:131196946..142307491 [NCBI36]
Chr8:8q24.21-24.3
pathogenic
GRCh38/hg38 8q24.22(chr8:133493189-134322208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052818]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052818]|See cases [RCV000052818] Chr8:133493189..134322208 [GRCh38]
Chr8:134505432..135334451 [GRCh37]
Chr8:134574614..135403633 [NCBI36]
Chr8:8q24.22
uncertain significance
1 to 10 of 91 rows

Predicted Target Of
Summary Value
Count of predictions:197
Count of miRNA genes:190
Interacting mature miRNAs:196
Transcripts:ENSMUST00000023243
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 60 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1301779Dpml_mdopamine loss (mouse)Not determined155100469476794493Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1558786Msq1_mMAV-1 susceptibility QTL 1 (mouse)Not determined156338964681086436Mouse

1 to 10 of 60 rows






Ensembl Acc Id: ENSMUST00000023243   ⟹   ENSMUSP00000023243
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1575,468,479 - 75,470,062 (+)Ensembl
GRCm38.p6 Ensembl1575,596,630 - 75,598,213 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1575,468,517 - 75,470,037 (+)Ensembl
GRCm38.p6 Ensembl1575,596,668 - 75,598,188 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189874   ⟹   ENSMUSP00000139792
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1575,468,503 - 75,471,330 (+)Ensembl
GRCm38.p6 Ensembl1575,596,654 - 75,599,481 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189944   ⟹   ENSMUSP00000139511
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1575,468,477 - 75,470,062 (+)Ensembl
GRCm38.p6 Ensembl1575,596,628 - 75,598,213 (+)Ensembl
Ensembl Acc Id: ENSMUST00000190119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1575,468,517 - 75,469,793 (+)Ensembl
GRCm38.p6 Ensembl1575,596,668 - 75,597,944 (+)Ensembl
RefSeq Acc Id: NM_001347039   ⟹   NP_001333968
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391575,468,479 - 75,470,062 (+)NCBI
GRCm381575,596,630 - 75,598,213 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001361294   ⟹   NP_001348223
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391575,468,479 - 75,470,062 (+)NCBI
GRCm381575,596,630 - 75,598,213 (+)NCBI
Sequence:
RefSeq Acc Id: NM_026730   ⟹   NP_081006
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391575,468,479 - 75,470,062 (+)NCBI
GRCm381575,596,630 - 75,598,213 (+)NCBI
MGSCv371575,427,088 - 75,428,643 (+)RGD
Celera1577,096,812 - 77,098,367 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_081006   ⟸   NM_026730
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9D1N2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001333968   ⟸   NM_001347039
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A087WNV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001348223   ⟸   NM_001361294
- Peptide Label: isoform 3 precursor
- UniProtKB: A0A087WPI6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000023243   ⟸   ENSMUST00000023243
Ensembl Acc Id: ENSMUSP00000139792   ⟸   ENSMUST00000189874
UPAR/Ly6

Name Modeler Protein Id AA Range Protein Structure
AF-Q9D1N2-F1-model_v2 AlphaFold Q9D1N2 1-228 view protein structure

RGD ID:6826073
Promoter ID:MM_KWN:18800
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_026730
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361575,427,221 - 75,427,721 (+)MPROMDB
RGD ID:8684012
Promoter ID:EPDNEW_M20037
Type:multiple initiation site
Name:Gpihbp1_1
Description:Mus musculus GPI-anchored HDL-binding protein 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381575,596,654 - 75,596,714EPDNEW


1 to 22 of 22 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000022579 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023243 ENTREZGENE
  ENSMUST00000023243.11 UniProtKB/Swiss-Prot
  ENSMUST00000189874 ENTREZGENE
  ENSMUST00000189944 ENTREZGENE
Gene3D-CATH 2.10.60.10 UniProtKB/Swiss-Prot
InterPro CD59_antigen_CS UniProtKB/Swiss-Prot
  Ly-6/neurotoxin-like_GPI-ap UniProtKB/Swiss-Prot
  LY6_UPA_recep-like UniProtKB/Swiss-Prot
  Snake_toxin-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:68453 UniProtKB/Swiss-Prot
MGD MGI:1915703 ENTREZGENE
NCBI Gene 68453 ENTREZGENE
PANTHER GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1 UniProtKB/Swiss-Prot
  UPAR/LY6 DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam UPAR_LY6 UniProtKB/Swiss-Prot
PhenoGen Gpihbp1 PhenoGen
PROSITE LY6_UPAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57302 UniProtKB/Swiss-Prot
UniProt A0A087WNV7 ENTREZGENE, UniProtKB/TrEMBL
  A0A087WPI6 ENTREZGENE, UniProtKB/TrEMBL
  HDBP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
1 to 22 of 22 rows