Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SKP1 mRNA | CTD | PMID:36331819 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SKP1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SKP1 mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SKP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SKP1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SKP1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SKP1 mRNA | CTD | PMID:17942748 | 2,4,6-tribromophenol | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of SKP1 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SKP1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of SKP1 gene | CTD | PMID:31601247 | 5-aza-2'-deoxycytidine | decreases expression | EXP | | 6480464 | Decitabine results in decreased expression of SKP1 mRNA | CTD | PMID:27915011 | acrylamide | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of SKP1 mRNA | CTD | PMID:28959563 | arsane | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Arsenic results in increased expression of SKP1 mRNA | CTD | PMID:19945496 | arsenic atom | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Arsenic results in increased expression of SKP1 mRNA | CTD | PMID:19945496 | arsenite(3-) | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SKP1 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SKP1 mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SKP1 protein | CTD | PMID:31675489 | Bisphenol B | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SKP1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SKP1 mRNA | CTD | PMID:28628672 | Brodifacoum | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of SKP1 protein | CTD | PMID:28903499 | calycosin | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | 7 and 3'-dihydroxy-4'-methoxyisoflavone results in increased expression of SKP1 mRNA | CTD | PMID:24455688 | cannabidiol | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Cannabidiol] results in decreased expression of SKP1 protein | CTD | PMID:34122009 | carbamazepine | affects expression | ISO | SKP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SKP1 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Nanotubes and Carbon results in decreased expression of SKP1 protein | CTD | PMID:22157353 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon results in decreased expression of SKP1 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SKP1 gene] | CTD | PMID:28238834 | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SKP1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SKP1 mRNA] | CTD | PMID:17585979 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of SKP1 mRNA | CTD | PMID:17585979 | clozapine | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Clozapine results in decreased expression of SKP1 protein | CTD | PMID:34122009 | coumarin | decreases phosphorylation | ISO | SKP1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of SKP1 protein | CTD | PMID:35688186 | Cuprizon | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Cannabidiol] results in decreased expression of SKP1 protein | CTD | PMID:34122009 | cyclosporin A | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SKP1 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of SKP1 protein | CTD | PMID:31675489 | deguelin | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | deguelin results in decreased expression of SKP1 mRNA | CTD | PMID:33512557 | dexamethasone | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SKP1 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SKP1 mRNA | CTD | PMID:28302478 | dimethylarsinous acid | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of SKP1 mRNA | CTD | PMID:20886546 | disodium selenite | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SKP1 mRNA | CTD | PMID:18175754 | endosulfan | affects expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Endosulfan affects the expression of SKP1 mRNA and Endosulfan affects the expression of SKP1 protein | CTD | PMID:31464424 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of SKP1 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of SKP1 mRNA | CTD | PMID:30319688 | fipronil | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of SKP1 mRNA | CTD | PMID:23962444 | flutamide | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of SKP1 mRNA | CTD | PMID:24136188 | folpet | increases expression | EXP | | 6480464 | folpet results in increased expression of SKP1 mRNA | CTD | PMID:31558096 | FR900359 | increases phosphorylation | ISO | SKP1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SKP1 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of SKP1 gene | CTD | PMID:31601247 | graphite | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Graphite results in decreased expression of SKP1 protein | CTD | PMID:22157353 | indometacin | multiple interactions | ISO | SKP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of SKP1 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SKP1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SKP1 protein | CTD | PMID:32959892 | methidathion | affects expression | EXP | | 6480464 | methidathion affects the expression of SKP1 mRNA | CTD | PMID:34813904 | methylisothiazolinone | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of SKP1 mRNA | CTD | PMID:31629900 | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of SKP1 mRNA | CTD | PMID:20061341 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | EXP | | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP1 mRNA | CTD | PMID:20061341 | nefazodone | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of SKP1 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of SKP1 mRNA | CTD | PMID:24136188 | paracetamol | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SKP1 mRNA | CTD | PMID:21420995 | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SKP1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SKP1 mRNA] | CTD | PMID:17585979 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of SKP1 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SKP1 mRNA more ... | CTD | PMID:36331819 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SKP1 mRNA | CTD | PMID:18301758 and PMID:23811191 | piroxicam | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of SKP1 mRNA | CTD | PMID:21858171 | sertraline | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Sertraline results in decreased expression of SKP1 mRNA | CTD | PMID:24865413 | sodium arsenite | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SKP1 mRNA | CTD | PMID:28595984 | sodium arsenite | decreases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | sodium arsenite results in decreased expression of SKP1 protein | CTD | PMID:29459688 | sodium arsenite | increases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | sodium arsenite results in increased expression of SKP1 mRNA | CTD | PMID:19072884 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of SKP1 protein | CTD | PMID:28918527 | T-2 toxin | affects expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | T-2 Toxin affects the expression of SKP1 protein | CTD | PMID:26141394 | thapsigargin | decreases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Thapsigargin results in decreased expression of SKP1 protein | CTD | PMID:35544339 | trichloroethene | decreases expression | ISO | Skp1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of SKP1 mRNA | CTD | PMID:33387578 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of SKP1 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Urethane results in increased expression of SKP1 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | SKP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SKP1 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SKP1 mRNA | CTD | PMID:23179753 | vitamin E | increases expression | ISO | SKP1 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of SKP1 mRNA | CTD | PMID:19244175 | zoledronic acid | decreases expression | ISO | SKP1 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of SKP1 protein | CTD | PMID:28871336 | |