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Gene: ITGA1 (integrin subunit alpha 1) Sus scrofa

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Symbol:

ITGA1

Name:

integrin subunit alpha 1

RGD ID:

14285476

Description:

ENCODES a protein that exhibits collagen binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cell chemotaxis (ortholog); cellular extravasation (ortholog); PARTICIPATES IN altered integrin mediated signaling pathway; integrin mediated signaling pathway; myocardial infarction pathway; ASSOCIATED WITH arteriosclerosis (ortholog); breast cancer (ortholog); COVID-19 (ortholog); FOUND IN acrosomal vesicle (ortholog); cell surface (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

integrin alpha-1; integrin, alpha 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITGA1 (integrin subunit alpha 1)	HGNC	Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Itga1 (integrin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Itga1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itga1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITGA1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITGA1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itga1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ITGA1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itga1 (integrin subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	32,129,612 - 32,304,592 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	32,130,265 - 32,309,917 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	33,940,969 - 34,132,541 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

arteriosclerosis (ISO)

breast cancer (ISO)

COVID-19 (ISO)

Gliosis (ISO)

Hyperalgesia (ISO)

Neurodevelopmental Disorders (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA,ISO)

cell adhesion mediated by integrin (IBA)

cell chemotaxis (ISO)

cell-cell adhesion (IBA)

cell-matrix adhesion (IEA)

cellular extravasation (IEA,ISO)

integrin-mediated signaling pathway (IBA,IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of epidermal growth factor receptor signaling pathway (IEA)

neuron projection morphogenesis (ISO)

neutrophil chemotaxis (IEA,ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of neuron apoptotic process (ISO)

vasodilation (ISO)

Cellular Component

acrosomal vesicle (ISO)

basal part of cell (IEA)

cell surface (IEA,ISO)

external side of plasma membrane (IBA,IEA,ISO)

focal adhesion (IEA)

integrin alpha1-beta1 complex (IEA)

integrin complex (IBA,IEA)

membrane (IEA)

perikaryon (ISO)

plasma membrane (IEA)

Molecular Function

collagen binding (ISO)

collagen binding involved in cell-matrix adhesion (IEA)

integrin binding (IBA)

metal ion binding (IEA)

phosphatase activator activity (IEA)

protein binding (ISO)

protein phosphatase binding (IEA)

signaling receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

altered integrin mediated signaling pathway (ISO)

integrin mediated signaling pathway (ISO)

myocardial infarction pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ITGA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	32,129,612 - 32,304,592 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	32,130,265 - 32,309,917 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	33,940,969 - 34,132,541 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ITGA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	52,787,916 - 52,959,209 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	52,787,916 - 52,959,209 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	52,083,750 - 52,255,039 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	52,119,893 - 52,285,242 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	52,119,892 - 52,285,241	NCBI
Celera	5	49,037,686 - 49,203,085 (+)	NCBI		Celera
Cytogenetic Map	5	q11.2	NCBI
HuRef	5	49,055,982 - 49,221,542 (+)	NCBI		HuRef
CHM1_1	5	52,086,786 - 52,252,111 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	53,615,621 - 53,786,944 (+)	NCBI		T2T-CHM13v2.0

Itga1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	115,094,615 - 115,238,500 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	115,089,632 - 115,238,500 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	114,958,079 - 115,101,964 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	114,953,096 - 115,101,964 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	115,748,287 - 115,892,172 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	116,080,957 - 116,222,842 (-)	NCBI		MGSCv36	mm8
Celera	13	119,308,615 - 119,462,806 (-)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI
cM Map	13	64.61	NCBI

Itga1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	48,379,181 - 48,545,336 (-)	NCBI		GRCr8
mRatBN7.2	2	46,646,125 - 46,812,237 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	46,653,193 - 46,812,238 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	53,760,440 - 53,912,547 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	51,818,812 - 51,971,755 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	46,688,983 - 46,841,874 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	47,127,403 - 47,281,387 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	47,127,219 - 47,281,421 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	71,666,601 - 71,823,120 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	47,107,849 - 47,206,261 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	47,036,084 - 47,134,488 (-)	NCBI
Celera	2	42,407,780 - 42,559,904 (-)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

Itga1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	14,446,300 - 14,577,605 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955446	14,439,571 - 14,582,236 (-)	NCBI	ChiLan1.0	ChiLan1.0

ITGA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	60,984,567 - 61,160,262 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	59,135,090 - 59,312,685 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	61,073,507 - 61,247,565 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	62,692,673 - 62,865,771 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	62,692,673 - 62,865,769 (-)	Ensembl	panpan1.1		panPan2

ITGA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	62,287,823 - 62,455,940 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	62,293,082 - 62,455,650 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	62,062,740 - 62,230,868 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	62,785,836 - 62,953,966 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	62,791,553 - 62,953,332 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	62,561,013 - 62,729,609 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	62,685,631 - 62,847,651 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	63,212,383 - 63,380,850 (-)	NCBI		UU_Cfam_GSD_1.0

Itga1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	205,502,947 - 205,654,957 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	14,443,685 - 14,591,380 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	14,442,481 - 14,591,574 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITGA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	49,081,687 - 49,248,321 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	49,082,787 - 49,246,186 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666082	1,876,808 - 2,052,640 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itga1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	6,404,758 - 6,543,211 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	6,397,743 - 6,543,652 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ITGA1
6329 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021076769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF330201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01069768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000018389 ⟹ ENSSSCP00000017893

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	32,185,484 - 32,295,491 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000082027 ⟹ ENSSSCP00000066771

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	32,130,235 - 32,304,592 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000088837 ⟹ ENSSSCP00000073887

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	32,187,560 - 32,295,491 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000092839 ⟹ ENSSSCP00000080756

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	16	32,129,612 - 32,295,491 (+)	Ensembl

RefSeq Acc Id:

XM_021076769 ⟹ XP_020932428

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	16	32,130,265 - 32,309,917 (+)	NCBI

Sequence:

show sequence

CCGAGCCCTTCCCTCCGATCCAGTGCGTCCCCGGGTCCCCCAGGGGCTGCGACCGCTCCGGCCA
TGGCCCCCCGGCGCCGCGCCAGCCCAGGGGTCGCTGTCGCCAGCTGCTGGCTCCTCACCGTTCT
TCTAGGCTTCTGCCTATCATTCAATGTGGATGTGAAAAACTCAATGACTTTCAGTGGCCCGGTG
GAGGACATGTTTGGATATACTGTTCAACAATATGAAAATGAAGAAGGAAAATGGGTGCTTATTG
GTTCTCCTTTAGTTGGCCAACCCAAGAACAGAACTGGAGATGTTTATAAGTGTCCAGTTGGGAG
AGGTGAATCATTACCTTGCATAAAGTTGGATCTACCAGTTACTACATCAATTCCCAATGTCACA
GAAGTAAAGGAGAACATGACATTTGGATCAACTTTAGTCACCAACCCAAAAGGAGGGTTTCTGG
CATGTGGGCCCTTATATGCCTACAGATGTGGACACTTGCATTACACAACTGGAATCTGTTCTGA
TGTCAGCCCTACATTTCAAGTCCTGAACTCAATTGCTCCAGTACAAGAATGTAGCACTCAGCTG
GACATAGTCATAGTGCTGGATGGTTCCAACAGTATCTACCCCTGGGAAAGTGTTACCGCTTTTT
TAAATGACCTCCTTAAAAGAATGGATATTGGTCCTAAACAGACACAGGTTGGAATTGTACAGTA
TGGAGAAAATGTAACCCACGAATTCAACCTCAATAAGTATTCATCAACAGAAGAGGTGCTTGTT
GCAGCAAACGAAATAGTCCAGAGAGGTGGCCGCCAGACCATGACAGCCCTTGGAATAGACACAG
CAAGGAAGGAGGCTTTCACTGAAGCCCGGGGCGCCCGAAGAGGGGTTAAAAAAGTCATGGTAAT
TGTGACTGATGGTGAGTCCCATGACAACCACCGACTGAATAAGGTCATCCAGGACTGTGAGGAT
GAAAGCATTCAGCGGTTTTCCATAGCTATTCTTGGCAGCTATAACCGAGGAAATTTAAGCACTG
AAAAATTTGTGGAGGAANATAAATCAATTGCAAGTGAACCCACAGAAAAACATTTCTTCAATGT
CTCTGATGAATTGGCGCTGGTTACTATTGTTGAAGCTCTGGGAGAAAGAATCTTTGCCCTGGAA
GCTACAGCTGACCAGTCGGCAGCTTCTTTTGAGATGGAAATGTCTCAGATGGGCTTCAGCGCTC
ATTATTCACAGGACTGGGTCATGCTCGGAGCAGTAGGAGCCTATGATTGGAATGGAACAGTCGT
CATGCAGAAGGCTAATCAAATCAAAATTCCCCCAAACAAGACCTTTAATGTCGAGTCTACCAAA
AAGAATGAACCTCTTGCTTCTTATTTAGGTTACACAGTAAACTCTGCCACTGTTCCTGAGGATG
TGATTTACATTGCGGGACAGCCACGGTACAATCACACAGGCCAGGTGGTCATCTACAGGATGGA
GAATGGGGGCATCAGGATTCTCCAGGCACTCAGAGGGGAACAGATTGGGTCCTACTTTGGCAGC
GTTTTAACGACAGTTGACATTGATAAAGATTCTAACACGGACATTCTTCTGGTCGGGGCTCCCA
TGTTCATGGGTACAGAGAAGGAGGAACAAGGAAAAGTGTACGTCTATGCCCTGAATCAGACAAG
GTTTGAATATCAAATGAGCCTGGAACCCATTAAGCAGACTTGTTGTTCATCTCTGAAGCACAAT
TCATGCACAAAGGAAAACAAAAATGAGCCATGTGGGGCTCGTTTTGGAACAGCTATTGCTGCTG
TGAAAGACCTCAATCTTGATGGATTTAACGACGTTGTGATAGGAGCGCCCCTGGAAGATGATCA
CGGGGGAGCTGTGTACATTTATCACGGCAGCGGCAAGACTCTAAAGGAAGAGTATGCACAACGT
ATTCCATCAGGTGGAGATGGTGAGACACTGAAATTTTTTGGCCAGTCTATCCACGGAGAAATGG
ATTTAAATGGTGACGGCCTGACTGATGTCACTATTGGGGGCCTTGGTGGTGCTGCCCTCTTCTG
GTCCCGGGACGTGGCTGTAGTCAAAGTGACCATGAATTTTGAACCCAATAAAGTGAATATTCAA
AAGAAAAACTGCCATATGGAGGGGAAGGAAACAGTATGCATAAATGCCACCGTATGTTTTGATG
TGAAATTGAAGTCCAAAGAAGACATGGTTTACGAAGCTGATATGCAGTACCGTGTTACACTAGA
TTCTCTAAGGCAGATATCACGGAGTTTTTTCTCTGGAACTCAAGAGAGAAAGATTCAAAGAAAC
ATCACAGTTCGAGAATCAGAATGCACTAAGCATTCCTTCTACATGTTGGACAAGCATGACTTTC
GGGACTCTGTGAGAATAACTGTGGATTTTAATCTTACTGATCCAGAAAATGGACCTGTTCTTGA
TGATTCTCTACCAAATTCAGTACATGAATATATTCCCTTTGCCAAAGATTGTGGCAACAAGGAA
AAATGTATCTCGGACCTCGCCCTGAATGTATTCACCACAGCAGAGGGCCTGCTTATTGTCAGGT
CCCACAATGATAAGTTCAATGTTAGCCTCACAGTCAAAAATAAGAAGGACAGTGCCTACAACAC
CAGAACCATAGTGAATTATTCTCCAAATCTGATTTTTTCAGGAATTGAGGCTATCCAGAAAGAC
AGTTGTGAATCCAATCATAACATCNACTGTAAAGTTGGATACCCTTTCCTGAGAAAAGGAGAAG
TGGTAACATTCAAAATATTATTTCAGTTTAACACATCTTATCTCATGGAAAATGTGGTCATTCA
TTTAAGTGCAACAAGTGACAGTGAAGAGCCTCCTGAAGCCCTTTTTGATAATGAAGTAAACATT
TCTGTTCCTGTGAAATATGAAGCTGGGCTACAGTTTTACAGCTCTGCAAGTGAGTACCACATTT
CAATTGCGGCAAATGAAACAGTTCCTGAAGTTATTAGTTCTACCGAGGACATTGGAAATGAAAT
TAATATCTTCTACTTGATTAGAAAAAGTGGGCAGTTTCCAATGCCCAAACTTAAGCTGTCCATT
TCATTCCCCAACATGACATCAGATGGTTTTCCTGTATTGTACCTGAGTGGATGGTCATCTTCTG
ATAATGCACACTGCAGACCCAGTAGCCTTCAGGATCCCTTCGGTATCAACTCTGGGAATAAGAT
GACTATATCCAAAGATCTTAAACGAGGCACCATGCAGGACTGCAGAACATGTAAATTTGCTACC
ATCATGTGTAATCTGATTCCTTCTGACATGAACCAAGTGAATGTTTCGCTTATCTTATGGAAAC
CAACTTTTATAAAAGTACATTTTTCCACCTTAAATCTTACTATAAGGGCAGAACTTGAAAGTGA
AAATACATCATTAGTTTTAAGTGCTGGTAATCAAAAAAGAGAGCTTGCTATTCAAGTATCCAAA
GATGGGCTGCCTGGCAGAGTACCATTATGGGTTATCCTGTTGAGTGCTTTTGCTGGATTGTTGC
TATTAATGCTGCTCATATTAGTACTGTGGAAGATTGGATTCTTCAAAAGACCACTAAAGAAGAA
AATGGAGAAGTGAAATATTTTAGAAGAGAAAAAATAACAATTATTCAATGATCCTTCCTCAGGT
TTGCCTCAAATATGTGACAAGAAATTTATAATAACAGTTAAAGACATAGTCACATAACTTTATG
TAATCCATCAGGGATTAATACCTTAGAAAGTGACAGATCAAGCAAGATCCAAAACAATACCTTT
AAGATATATTTTATAAAATGTTGAAAAGTATTTTTAAATAATTACTCATTTTTGTTGAGTATTT
AAGCAAAATTACAAAGTGTTTTGAAGATGAAAAGTAACCTGTACAAATATGTTTATATATTAAA
TCATCATTCAAAATATTTAAGGAATACATAAAATATTTTATAATCATTGAAATATTTACTTTGA
AAAACAATATAAATTAAGGTTTTTTTCATTGATTCCTGATGGATATCCACATTCAGCATGATAG
TCAACATTTGTAAATGCCAAGAAAGGAATTACCTGAAAAAGATCACTTCCCCCTATTTAAATGA
CAAAAAGTTCCCTGGTGGAGTCTGTCTACAATATGGACTGAAAATAGAATTAAATCACTGCGAA
TACATTCAGCATCTTTGTGTTGGGTTCTGTGCTTGGAAAGTTTTCTTTCCAAAGTACTTGGAAA
ACAGTGTAATTGAGCTGAAATTCTATCTAGGATAGAAATTCAAGATAGACTTGTTTAAAAGCAA
GTGCACTGTATGGATTAATTTAAGCTTTTACAGAACATGCTTAATTTTGATATTGAACTCTAAA
ACTCAAAACTCTTTTATACTGAAAAAGCACAACAATTTTTTATGGTGTAGCAGTGATTGTCACA
AAAAAATTGCTTTGTCTGTGGACTGTGTTAAAATGGTTTCTTAATGGAGTATGGCAATGTAGAT
GTGTGCATCGAAATGCTGGTCATCTTTGCTGGGCAGCTTTTAACATGAGGGGTCCCAGGTGTAA
CCAAAAGTAGGAGTTGGCTCAATTCCTTGGTACATGGTTCATTCAAACCCTCAAGCTGTGAGAG
TATGTTTTATTTTTAATATTTTTACAGGTATTTAATTTTCCAAACATAGTTCTTCTTTTTATAA
AAAGGCAGTATTCCATTTTAGTATTGCATTTTACCAATAAGCCACTAATTTTTGAGTGTGGCAT
ATCAGTATTTAAATAGATCTCCAGAAATGTATTTTAAAGAATTTCGGGTTTGAAAACCTGGCCC
CAACAGAAAGACATCACACCTTTTTATGAGCATCTTTGTTCTTGAAGTAATCATTATGGTGCCT
TGGGCTCTACTGTAGCTTAAGCTCCTTGGTTTCTCAATTTCCTGGGGTTGGGGGGGGGTGGATA
ATGAATGAATGTATATGTGAACTACTGCTGTAAAATTTGCTGATCCTTCTGCAACAACTCCATG
TCTCCACCTGATTGACCATCACAAGATCAGAGCCTGTAATTATCCACAAAGTCCTACTCTTCTC
AAAAAGCAACAAATGAGTGGAGAAGTTAAATGCCATGAATTTAATTTTTAAAAACTAATTCCGT
GGAGTTCCTTGATGGCTCAGAAGGTTAAGGATCTGGCATTGTCCCTGCTGTGGCTCTGGTTGCC
CCAGGAACTTCCCTATGCCGCGGGCACAGCCAAAAAAAAAAAAAAAAAAAAAAAAATTCCAGGG
AATTGTCTATGGACTCAAAGGCAGCCTACCTCATGGCTCTCTACATCTACATCTAAGATCCTGG
TGGTCAAAAGCATGCACCTGGGGAGAGCTGAAGTCATCAGTAGCTAGAAGAAAGGCTAAATCTT
TCCAGAGAGTCATATCCTCTTGCTGGCCTGTCATTGCTCAGAAATGTCCAATTTTAGAATTTTC
TTCATTCCTGCTATCTGCCTTCAGGTTTAGAAATCATTCTTTCCACCTGTTCTTTTTCTGCTCA
ACCAAACTCAGGTCTCTCTGATTCAGAGTCACCATGTTGCACAACCCCAGTGCACATGCTCACA
GCTCTGCTCCAAGCTCGGCGCATTCTTAGAAATAAGTCTAACAGATAAAAATTTTAAAATTCAT
GCTTGTACTCTGTGACTGCTGGGCAAAGCATGCATTGAACCAGGAGTGTTGCACATTTCAACTA
ATATGTTGTTAACCCAAAGGGGAAAAATAGAAAAGATGGCATTTGAAACTTTTTAGAAAAGAGA
GGAAGAGCTATTTGATCTGATCCTAATGAAATTGCTGCTTATAATAAGCCTGGCAAAATTTTTA
ACATAAATAATTCCTGGGTTTTAAGTAGACTATTTAATGAGCCAGATATCCCATTTCCCTAACA
TTGTAATTTGTTGAGGTTTATGTGCATATGTGTGTATCTGTGCATATGTATGTATATCAACACA
CATACACACACATACACATGCACACATGCATGGACACAAATTGAAGGAAAAAAATAACTCAACG
CCAAGTGGCAGAGTTTATATAAAATAAACACACAAAAACTACACCACAAAAAAATTCAATTTGT
TCACTCTGTATATAGTTTTCACTTTCATTAATATTTAACTGTAGCATTCAGTTATGCAACTATC
TAAAAGTCATAAATGTAGAGGCTTTGACCAAGATACTAACTCAACAGATGCCCCAAATTGGCTT
TGTACAAATATTCTAAAACACCATCAATGATTAAGAAATATACTAAACTCTATCATTTGATTTT
AAAACACTTAATCAGAAAAATGATACGTAAGACATTTATGAGCTTACTGGTTAAATCAAATTGC
AAAACACTTTCTTTTTGAAACTTTGATGTCTTTTAAATTAATCATTGCTTCCACTGTGAACTGA
ACTATGTATGCATCTCCTTCTCAGACCAAACCTACAATGGTATATTATTGGTAAATTATTTAAC
AACTGGCTCTCCAGGAGGAAATAAATCCCTGAGTTGTGTCATTTGCCAATTTCCATGATCTGAA
TAGTTTGCCATGGCCATTTTCAAGCTACCAACAATAGCCCTAACCAGCTTGCAAAATTCCTGAA
AATGTATTTGTTAGCTTTCATGAACCAGTATGAGCTGGCTTCAGTGCACTATTGAGACAGATTA
GATGTCAATGATAAAGAAAGAGAAGGAAGGGAGGGAGGGAGGGAGGGAGGAGGAAGGAAAAGAG
AAAGGGTGGAAGGGGGGAGAAAAAGGAGAGAAAGGAAAGAAGAAAGAAAGGAAAGAAGACAAAA
ATATTCTTAAAATGCTAATCTCAAGCCCAGAAGACATAATTCTACATAGTTCCCAATTCTTCAA
TTCAATTTCTAAAAGTATAGCCTTCCTTTAATATTAATAAAATGATATAAATCTGCAGGAAAAG
GAAGGAGTTGAAAGCAAAACAATGTCAAGGGTGACACACTAAAAATCAGACCTCTGCAGCCACA
GAGAAGCTGTTTCACTTTCTCTGGGAATCCAGAGCCCTGGAGCCAGACTGTGAAAGGTCATCCT
TGGTAAAAAAAATTGTAATTTCTGGGATCCAGTTTGAACTTCAGTGATCCAATTTGTCCAATTA
TTTTTCTCCAAGCACTCGATTCATGGGTGATGTAATCTCTGAATATTTTCTGTGTCACAAGCGT
CCTTGAAACAACTTGTGGGAGGACATATTTTTACAAAATTTGGTGCTTACTCAAGCATAATCAT
TTATCATTTTACCTTCTATAAAAGCAGTATCTAGGCTCAATTGGAAAACAAGTGTTCGCTCCAG
AGCGAAAGGTGGTTGCACAGTGCTTGCGGAAAGCCGAGTGGGAGGAGAGGCCGAGAGAAGGTCT
GGTGTGTTCTCTGCAGGCAGCCCCAAAGGGCCACCGCTTGCACTGTGCCAAGGGCTGCCCGCCA
GCTTCTATGCAGTGCACTTTCCCGCAGGAAATCCTCACTGTCAGATATGCAACCTGCTCCGTGG
GAACCGTCTTGCTCCACATAACGCTGAGAAAACTCGGGAAGACCCGGGCTCCGAGCATGGTTCA
TGTGCCAGAGACAGTCATGTGCTCGAATAAAGAGGCCTCTGGCAAATCAGGGTTTGCAAAACAG
TATCCTACATACCCTTTGCTGATTTTCAACACTTCTCGAGTCTCCCTCCATTAGTCTTCTCCTC
CAAAGAAGACTTCCAAGAAGGCCCCTAGAGAAAAATCTGTTTAAATCATGTGCTCTGTTTGCTG
TGAGGACCAGCTCTGTGATTTGATCACTGACACAGATTTCAGTCCTCTGTTCTTCTGTGGCACT
CTAAAGGGTTGATATGGTATAATATAGTGGAGACAAAAAGAAAGGCATTTCAGACATGGAGCAG
CTTAAAGAAATTTGCAAATACTCTCAGTACCTGTGACAGTTGAGGGGCTGGCAGGATTTAGCCC
CTCAGTGGGGCTCCATCAGCATCCCTAATCCCATCCTCACCCTTGGAAATAATAATCTAAAAAA
CAAAAAGAAGAGCTGTAAAATCCTCAAAGTGGTACTATTTTTTAATTAAAGTATACAGTCTAAC
TGTAAACAGCAGGCATTTTAATGCAAATACAACTTCAAGGTGATTCCACTGGGCAACCCTTCCA
ATCAGACTTCTGTCCCTAAACACCTCCTACCCAGAAATTCAGAAACCTCCACTGAAGGTGAACT
GTGTTGTGCCTTACAAAAGACTAAATACTGCCACTTCCTGAATGGGAGCGCTGTTATGCAACAT
TTTACGTAAAACAATAAAAAAGAGTTCAAATCTAACATTGTCATCTGGTGAATGAGTCACTATT
TTTTTATCCTCCTATTAAAATGTAACCTTGAATTTGGAAATTCCAAGTGAGGATCTTTAACCAC
CAACCTTGAGAGAAAGTACAGGAGCCTAGGTAGGCTCTTCCGCCCCAGCCCCATCATCCTCTAC
CTCTGGTGCCCAAGAGGTCCAGTTCTTAAGCCTGAGCTCCTGAATCCACAGTGTCCCAGGATCA
GCCCTCCCACATCAGACGTACACATAAACACTGGCTGAAGTTTTACCATACCAAAAAATTTACA
AGGATGAATTATCACTTGTAATGTTGGACTCCCTGCTTTGAGATCGGCATTTTTTTTTTTTTTT
TCTCCCTTTGAAAGTATAAGAAAGCCTTTCTCTCAGAGCTAATGAGTTCAGAGCTTTATACTAG
ACTTCCAGGCTAGAGAATTTCAAGGCCTGGAGGACCTGGCACTAGGACCCAGGGCCCATTTGCA
GGATCTCTCTGCTTTCTGCTTCCCAGATGGTTTCCTCTCTTCTCAGCTGTACGGTGGGGAATGT
TTGGTTTTAATTTGGGTTCTCTTGGCAAGGCCATGCTAAGCCTGGTGCGCCTCGAAGGGCCTTG
AGGGCTAGATGTTCTTTGTTGGAGAGTTGAGGCTTGGAAATCCTTTACGTATCTGACACACTGT
GGAAATCATGGCAATATCTAGGCGACGCCAGTGACACGCATAACTATGACTATGTTTGATCTTA
ACCATGTTTCAAGTGACATCATGATGGAAAAAGACTAAGTCTGGAATTTCAGGGGCATTTCAGC
AACACTGAGACTCCGAATTGAATGTTTCATTGCAGTTTAATCTACGCATGAAGCTTAAGAGCAA
AATTTTGTAAAGAAATCTTCCCAATGACAATGAAAGCCAGGTGTCTTCTTGAACAGTCCCCTGC
TGACAGTTCCTGTCCCCACCCCTATTTTTTAAAAGCCGGAAAGAAGATTAAATGGGGAAAAATG
AGTGGCATCATTGTTTCTTTCTGCTACAGAGGAGCCACGTAGGAGGGAGTCAGCACACAGCATA
GGCACTGTGGCTTTCTGAGAGGTCTTAGCATCATAGGTCCAGTGGCAGGTGACAGTGTTCCTGC
CATGGCCCTGAGGCATCTTGGATCCTGAGAGACAAAAAAAATGGGGCAGGGGGAGGAGATGAAG
CAATTTATCTTTTTTGTATGTACACTTACTCCTCTAAATACTGTAAGCTCCCGTAGACCACTTC
ATTCTGGCCACAGTACCAACACATGTACTTCACACAAGTAAATTATTAATTAAATAAGAGTAAA
AATATATTCTTGCCTGTCTATTAACTAGGACTAATTTCCTGGTGTTTAACATACTTTGGCTCAA
GTAAAAACAACCATTTGAAGCAGCAATGGTTCAGATCTTCTTCATACTAGGACCAGTTCACACA
GTATATCCCAATACTGAGTGTTTAATTGAGAGAGACCCCTGCCCTTATTCAGGATGCAACAGCC
ACCTTCTGCATTCCTCCTAAGGGAACGGTGACCTGGAATGAGAATGGTGTACTGTGTGTTACTA
CTGTAAGGATGTAAAGTTACCGGATTGTGTCCATTTTATTAAAAAGGCAAACATTGTCTATAGT
AACTACTGCTCTGAAATATATATTATACGCACTCCAATAAACTTCTGCATGGCCTAACAAAGTA
TATTCATTGCTTATTTTTTATTTACCTCGGAATAAATTCATTAAAATGAATAACAAGGGCATGT
GCATTTTTATGACTTTTATCAGACCAACTCGCTAGAAGAAAATGCTTTGATTGCACTCAAGAAC
AAAGAAGTATGAACTGTGTTGATTCTAGTAATTTATTAAGTGCCAAATTTCAACGCATTTTTAA
AAAGAAATCTGTTATGGGTAACAATGATCTAAGTTGTTATATTTAGAAATAGCTGAGTTGAAGA
GTGTTTTGAATGTCCTATGTATGGTGCATCCTGTACACTGATTTAAGGTCAGAAGTTTGATATT
TTTGTATAATTCTATCTTATCTTGTGCATCAGCTGTGTATTTTACGTCAAGGTAAATGAACATC
CTGTCATATGTTAAATAAAAAATGACTCTTTCAAAGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020932428	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL09467	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017893.3
	ENSSSCP00000066771
	ENSSSCP00000066771.1
	ENSSSCP00000073887.1
	ENSSSCP00000080756.1
	ENSSSCP00065049639.1

RefSeq Acc Id:

XP_020932428 ⟸ XM_021076769

- UniProtKB:

A0A5G2R836 (UniProtKB/TrEMBL), A0A8D2CJB6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPRRRASPGVAVASCWLLTVLLGFCLSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLI
GSPLVGQPKNRTGDVYKCPVGRGESLPCIKLDLPVTTSIPNVTEVKENMTFGSTLVTNPKGGFL
ACGPLYAYRCGHLHYTTGICSDVSPTFQVLNSIAPVQECSTQLDIVIVLDGSNSIYPWESVTAF
LNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAANEIVQRGGRQTMTALGIDT
ARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLNKVIQDCEDESIQRFSIAILGSYNRGNLST
EKFVEEXKSIASEPTEKHFFNVSDELALVTIVEALGERIFALEATADQSAASFEMEMSQMGFSA
HYSQDWVMLGAVGAYDWNGTVVMQKANQIKIPPNKTFNVESTKKNEPLASYLGYTVNSATVPED
VIYIAGQPRYNHTGQVVIYRMENGGIRILQALRGEQIGSYFGSVLTTVDIDKDSNTDILLVGAP
MFMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSLKHNSCTKENKNEPCGARFGTAIAA
VKDLNLDGFNDVVIGAPLEDDHGGAVYIYHGSGKTLKEEYAQRIPSGGDGETLKFFGQSIHGEM
DLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD
VKLKSKEDMVYEADMQYRVTLDSLRQISRSFFSGTQERKIQRNITVRESECTKHSFYMLDKHDF
RDSVRITVDFNLTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLALNVFTTAEGLLIVR
SHNDKFNVSLTVKNKKDSAYNTRTIVNYSPNLIFSGIEAIQKDSCESNHNIXCKVGYPFLRKGE
VVTFKILFQFNTSYLMENVVIHLSATSDSEEPPEALFDNEVNISVPVKYEAGLQFYSSASEYHI
SIAANETVPEVISSTEDIGNEINIFYLIRKSGQFPMPKLKLSISFPNMTSDGFPVLYLSGWSSS
DNAHCRPSSLQDPFGINSGNKMTISKDLKRGTMQDCRTCKFATIMCNLIPSDMNQVNVSLILWK
PTFIKVHFSTLNLTIRAELESENTSLVLSAGNQKRELAIQVSKDGLPGRVPLWVILLSAFAGLL
LLMLLILVLWKIGFFKRPLKKKMEK

hide sequence

Ensembl Acc Id:

ENSSSCP00000073887 ⟸ ENSSSCT00000088837

Ensembl Acc Id:

ENSSSCP00000066771 ⟸ ENSSSCT00000082027

Ensembl Acc Id:

ENSSSCP00000017893 ⟸ ENSSSCT00000018389

Ensembl Acc Id:

ENSSSCP00000080756 ⟸ ENSSSCT00000092839

Protein Domains

VWFA

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016885	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00065079251	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000018389.3	UniProtKB/TrEMBL
	ENSSSCT00000082027	ENTREZGENE
	ENSSSCT00000082027.1	UniProtKB/TrEMBL
	ENSSSCT00000088837.1	UniProtKB/TrEMBL
	ENSSSCT00000092839.1	UniProtKB/TrEMBL
	ENSSSCT00065110195.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.130	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	Bicelle-embedded integrin alpha(iib) transmembrane segment	UniProtKB/TrEMBL
	Integrin domains. Chain A, domain 2	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 3	UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 4	UniProtKB/TrEMBL
InterPro	FG-GAP	UniProtKB/TrEMBL
	Int_alpha_beta-p	UniProtKB/TrEMBL
	Integrin_alpha	UniProtKB/TrEMBL
	Integrin_alpha-2	UniProtKB/TrEMBL
	Integrin_alpha_C_CS	UniProtKB/TrEMBL
	Integrin_alpha_Ig-like_2	UniProtKB/TrEMBL
	Integrin_alpha_Ig-like_3	UniProtKB/TrEMBL
	Integrin_alpha_N	UniProtKB/TrEMBL
	Integrin_dom_sf	UniProtKB/TrEMBL
	VWF_A	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
NCBI Gene	ITGA1	ENTREZGENE
PANTHER	INTEGRIN ALPHA	UniProtKB/TrEMBL
	INTEGRIN ALPHA-1	UniProtKB/TrEMBL
Pfam	FG-GAP	UniProtKB/TrEMBL
	Integrin_A_Ig_2	UniProtKB/TrEMBL
	Integrin_A_Ig_3	UniProtKB/TrEMBL
	Integrin_alpha2	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
PRINTS	INTEGRINA	UniProtKB/TrEMBL
	VWFADOMAIN	UniProtKB/TrEMBL
PROSITE	FG_GAP	UniProtKB/TrEMBL
	INTEGRIN_ALPHA	UniProtKB/TrEMBL
	VWFA	UniProtKB/TrEMBL
SMART	Int_alpha	UniProtKB/TrEMBL
	VWA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53300	UniProtKB/TrEMBL
	SSF69179	UniProtKB/TrEMBL
	SSF69318	UniProtKB/TrEMBL
UniProt	A0A5G2R836	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2RG33_PIG	UniProtKB/TrEMBL
	A0A8D2CJB6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8W4FMN7_PIG	UniProtKB/TrEMBL
	F1SMF6_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:89231	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations