XBP1 (X-box binding protein 1) - Rat Genome Database

Name: XBP1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: XBP1 (X-box binding protein 1) Sus scrofa

Analyze

Symbol:

XBP1

Name:

X-box binding protein 1

RGD ID:

14282980

Description:

ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); histone deacetylase binding (ortholog); INVOLVED IN adipose tissue development (ortholog); angiogenesis (ortholog); cellular response to amino acid stimulus (ortholog); PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; forkhead class A signaling pathway; ASSOCIATED WITH Acute-On-Chronic Liver Failure (ortholog); borna disease (ortholog); Breast Cancer, Familial (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH cadmium atom; cadmium dichloride; deoxynivalenol

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

X-box-binding protein 1; XBPP1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	XBP1 (X-box binding protein 1)	HGNC	Ensembl, NCBI, OrthoDB
Mus musculus (house mouse):	Xbp1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Xbp1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Xbp1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	XBP1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	XBP1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Xbp1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	XBP1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Xbp1 (X-box binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	46,008,377 - 46,016,526 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	46,011,239 - 46,016,526 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	49,015,849 - 49,016,650 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute-On-Chronic Liver Failure (ISO)

borna disease (ISO)

Breast Cancer, Familial (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

genetic disease (ISO)

glucose intolerance (ISO)

high grade glioma (ISO)

Hypertriglyceridemia (ISO)

inflammatory bowel disease (ISO)

Insulin Resistance (ISO)

Major Affective Disorder 7 (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

multiple sclerosis (ISO)

Peritoneal Fibrosis (ISO)

polycystic liver disease (ISO)

Polycystic Liver Disease 1 (ISO)

Spinal Cord Injuries (ISO)

steatotic liver disease (ISO)

vestibular schwannomatosis (ISO)

Zika fever (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

cadmium atom (EXP)

cadmium dichloride (EXP)

deoxynivalenol (EXP)

glycine betaine (EXP)

glyphosate (EXP)

menadione (EXP)

tauroursodeoxycholic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

angiogenesis (ISO)

cellular response to amino acid stimulus (ISO)

cellular response to antibiotic (ISO)

cellular response to fluid shear stress (ISO)

cellular response to fructose stimulus (ISO)

cellular response to glucose starvation (ISO)

cellular response to glucose stimulus (ISO)

cellular response to insulin stimulus (ISO)

cellular response to interleukin-4 (ISO)

cellular response to laminar fluid shear stress (ISO)

cellular response to leukemia inhibitory factor (ISO)

cellular response to lipopolysaccharide (IEA)

cellular response to nutrient (ISO)

cellular response to oxidative stress (ISO)

cellular response to peptide hormone stimulus (ISO)

cellular response to vascular endothelial growth factor stimulus (ISO)

cholesterol homeostasis (ISO)

endoplasmic reticulum unfolded protein response (ISO)

endothelial cell proliferation (ISO)

epithelial cell maturation involved in salivary gland development (ISO)

exocrine pancreas development (ISO)

fatty acid homeostasis (ISO)

glandular epithelial cell maturation (ISO)

intracellular triglyceride homeostasis (ISO)

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ISO)

liver development (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (IEA)

negative regulation of endoplasmic reticulum unfolded protein response (ISO)

negative regulation of ERK1 and ERK2 cascade (ISO)

negative regulation of myotube differentiation (ISO)

negative regulation of SMAD protein signal transduction (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of transforming growth factor beta receptor signaling pathway (ISO)

neuron development (ISO)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of angiogenesis (IEA)

positive regulation of autophagy (ISO)

positive regulation of B cell differentiation (IEA)

positive regulation of cell migration (IEA)

positive regulation of cell population proliferation (IEA)

positive regulation of endoplasmic reticulum unfolded protein response (IEA)

positive regulation of endothelial cell apoptotic process (ISO)

positive regulation of fat cell differentiation (ISO)

positive regulation of hepatocyte proliferation (ISO)

positive regulation of immunoglobulin production (IEA)

positive regulation of interleukin-6 production (ISO)

positive regulation of lactation (ISO)

positive regulation of MHC class II biosynthetic process (IEA)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of plasma cell differentiation (IEA)

positive regulation of protein acetylation (ISO)

positive regulation of protein import into nucleus (ISO)

positive regulation of protein phosphorylation (ISO)

positive regulation of T cell differentiation (IEA)

positive regulation of TOR signaling (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of vascular associated smooth muscle cell migration (ISO)

positive regulation of vascular associated smooth muscle cell proliferation (ISO)

positive regulation of vascular wound healing (IEA)

protein destabilization (ISO)

regulation of autophagy (ISO)

regulation of cell growth (ISO)

regulation of DNA-templated transcription (IEA)

regulation of protein stability (ISO)

regulation of transcription by RNA polymerase II (IEA)

response to electrical stimulus (ISO)

response to endoplasmic reticulum stress (ISO)

response to insulin-like growth factor stimulus (ISO)

response to nutrient (ISO)

response to xenobiotic stimulus (ISO)

serotonin secretion, neurotransmission (ISO)

sterol homeostasis (ISO)

transcription by RNA polymerase II (ISO)

ubiquitin-dependent protein catabolic process (ISO)

vascular endothelial growth factor receptor signaling pathway (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (ISO)

nucleus (IBA,IEA)

RNA polymerase II transcription regulator complex (IEA,ISO)

Molecular Function

chromatin DNA binding (ISO)

cis-regulatory region sequence-specific DNA binding (IEA)

DNA binding (IEA)

DNA-binding transcription factor activity (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

histone deacetylase binding (ISO)

identical protein binding (IEA)

phosphatidylinositol 3-kinase regulatory subunit binding (ISO)

protease binding (ISO)

protein binding (ISO)

protein heterodimerization activity (IEA)

protein kinase binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,IEA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (IEA)

transcription cis-regulatory region binding (ISO)

ubiquitin protein ligase binding (ISO)

ubiquitin-like protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

endoplasmic reticulum stress - the unfolded protein response pathway (ISO)

forkhead class A signaling pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:21605464	PMID:22190710	PMID:29058795	PMID:30032202

Genomics

Comparative Map Data

XBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	46,008,377 - 46,016,526 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	46,011,239 - 46,016,526 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	49,015,849 - 49,016,650 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

XBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	28,794,560 - 28,800,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	28,794,555 - 28,800,597 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	29,190,548 - 29,196,557 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	27,520,548 - 27,526,560 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	27,515,102 - 27,521,114	NCBI
Celera	22	12,990,518 - 12,996,530 (-)	NCBI		Celera
Cytogenetic Map	22	q12.1	NCBI
HuRef	22	12,155,463 - 12,161,487 (-)	NCBI		HuRef
CHM1_1	22	29,149,582 - 29,155,594 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	29,255,848 - 29,261,869 (-)	NCBI		T2T-CHM13v2.0

Xbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	5,470,641 - 5,475,993 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	5,470,659 - 5,475,893 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	5,520,641 - 5,525,993 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	5,520,659 - 5,525,893 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	5,420,970 - 5,425,875 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	5,420,970 - 5,425,875 (+)	NCBI		MGSCv36	mm8
Celera	11	6,013,954 - 6,018,865 (+)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	3.61	NCBI

Xbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	84,604,623 - 84,609,707 (+)	NCBI		GRCr8
mRatBN7.2	14	80,390,629 - 80,395,713 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	80,390,643 - 80,395,693 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	84,792,890 - 84,797,957 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	86,033,004 - 86,038,075 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	82,482,326 - 82,487,393 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	85,753,736 - 85,758,820 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	85,753,760 - 85,758,145 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	86,423,839 - 86,428,923 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	86,151,910 - 86,156,975 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	86,171,054 - 86,176,119 (+)	NCBI
Celera	14	79,276,264 - 79,281,348 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

Xbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955455	3,037,885 - 3,041,827 (-)	NCBI	ChiLan1.0	ChiLan1.0

XBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	38,792,985 - 38,799,011 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	41,491,735 - 41,497,760 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	9,863,479 - 9,869,491 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	27,566,423 - 27,572,627 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	27,567,041 - 27,571,943 (-)	Ensembl	panpan1.1		panPan2

XBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	22,162,675 - 22,168,149 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	22,163,222 - 22,168,105 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	22,034,265 - 22,039,738 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	22,536,044 - 22,541,803 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	22,536,033 - 22,541,796 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	22,246,365 - 22,251,835 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	22,509,837 - 22,515,563 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	22,572,658 - 22,578,379 (-)	NCBI		UU_Cfam_GSD_1.0

Xbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	112,975,309 - 112,979,534 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936657	2,891,907 - 2,896,174 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936657	2,891,171 - 2,895,409 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

XBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	11,670,605 - 11,677,168 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	114,476,586 - 114,483,163 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Xbp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624747	5,123,085 - 5,128,465 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in XBP1
45 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	4	3	5	2	22	2	3	3
Low						1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001142836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001271738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK233029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK392484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CJ017293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CT954243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU468554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ213449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01026658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000035419 ⟹ ENSSSCP00000030251

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	46,008,862 - 46,017,036 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000043460 ⟹ ENSSSCP00000056167

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	46,011,349 - 46,016,526 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000047245 ⟹ ENSSSCP00000048871

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	46,008,377 - 46,016,526 (-)	Ensembl

RefSeq Acc Id:

NM_001142836 ⟹ NP_001136308

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	46,011,239 - 46,016,526 (-)	NCBI

Sequence:

show sequence

AGACACGCTCCAGCCATGGTGGTGGTGGCAGCTGCGCAGAGCCCGACCGCCGGGGCCCCCAAAG
TACTGCTTCTCTCCGGGAAGCCCGCCGCCGCCGCCGCCGCTGGAGCTCCGGCCGGCCGGGCTCT
GCCTATCATGGTGCCGGGCCAGCGAGGGGCCAGCCCGGAGGCGGCAAGCGGGGGGCCGCCCCAG
ACGCGCAAGAGACAGCGCCTCACGCACCTGAGCCCCGAAGAGAAGGCGTTACGGAGGAAATTGA
AAAACAGAGTAGCAGCTCAGACTGCCAGAGACCGAAAGAAAGCTCGAATGAGTGAGCTGGAGCA
ACAAGTGGTAGATTTGGAAGAAGAGAACCAAAAGCTTTTGCTAGAAAATCAGCTTTTACGAGAG
AAAACACATGGCCTTGTAGTTGAGAACCAGGAGTTAAGACAGCGCTTGGGGATGGATGCCTTAG
TTACTGAAGAGGAGGCAGAGACCAAGGGGAATGGAGCGGGGCCGGTGGCCGGGTCTGCTGAGTC
CGCAGCACTCAGACTACGTGCACCTCTGCAGCAGGTGCAGGCCCAGTTGTCACCCCTCCAGAAC
ATCTCCCCATGGATTCTGACGGTGTTGACTCTTCAGACTCTGAGTCTGATATCCTCTTGGGCAT
TCTGTTCAACTTGGACCCAGTCATGTTCTTCAGATGTCCTTCCCCAGACTCTGCCAGCCTGGAG
CAGCTCCCAGAAGTCGACCCAGAAGGACCCAGTTCCTTACCAGCCTCCCCTTCTTCATCACTGG
GGACGTCACCAGCCAAGCTGGAAGCCATTAATGAAGTGATTCGTTTTGACCACGTATATACAAA
GCCCCTAGTCTTAGAGATTCCCTCTGAGACAGAGAGCCAAGCTAATGTGGTAGTGAAAATTGAG
GAAGCACCTTCCAGCCCCTCAGAGAAAGATCGCCCTGAATTCACTGTCTCAGTGAAGGAAGAAC
TTACAGAAGATGACTTCATTCCAGAGCTGGGTATCTCAGATCTGCTTTCAACCAGCCACTGCCT
AAAGCCATCTTCCTGCCTACTGGATGCTTATAGTGACTGTAGCTATGAGGGTTCCCCTTCTCCC
CTAAGTGACATGTCCTCTCTGCTTGGTGTAGACCATTCGTGGGAGGACACTTTTGCCAGTGAAC
TCTTTCCCCAGCTGATTAGTGTCTAAGGAGTGATCAGTACTGTTAACCCTTTTTCTTGACTATT
ACACTGCCTGGAGGATAGCACAGAAGCCTGTGGTTCATTCAGAAAGCTAGAGTAGAGGGTGTAC
AGTCCTAGAGTATTCCTCTAATATATTTGTTCAAACCTCATAGGTCACCCCAGGTATTGTCTTT
TGACATTCAGTGGTCTAGGACATGCAGGTTGTTACTATAATCCAGAATTATGGCTTCTGAGGTA
CCTTTATCTTAAGGGCAGTGGTTTGCCCTAAAATACTTGGGTAAGGGTCACTGGACAAGTGTCC
TAGACATGGAATTAATGAATGGCCCTTTATCATTTCTCTTCACCCCTTCTTGGCATCCCAGGCT
TGCCTCTGATTTTAGGTCCTTTAGTTTGCTTCTGCAGGCAGAGAGAATGCCTACCTGAGGGGGC
TCCTTTTCCTTCATGTACAGTTCAAGTAAAGATCAAGAATCTTTTGTGAAATTATTGAAATTTA
CTATGTAAATGCTTCACAGAATCTTTCCCAGCTAGTGTAACTTTTGGAAGGTGCTTTCTCCATT
TATTTAAAACTACCTGTGCAATTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001271738 ⟹ NP_001258667

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	46,011,239 - 46,016,526 (-)	NCBI

Sequence:

show sequence

AGACACGCTCCAGCCATGGTGGTGGTGGCAGCTGCGCAGAGCCCGACCGCCGGGGCCCCCAAAG
TACTGCTTCTCTCCGGGAAGCCCGCCGCCGCCGCCGCCGCTGGAGCTCCGGCCGGCCGGGCTCT
GCCTATCATGGTGCCGGGCCAGCGAGGGGCCAGCCCGGAGGCGGCAAGCGGGGGGCCGCCCCAG
ACGCGCAAGAGACAGCGCCTCACGCACCTGAGCCCCGAAGAGAAGGCGTTACGGAGGAAATTGA
AAAACAGAGTAGCAGCTCAGACTGCCAGAGACCGAAAGAAAGCTCGAATGAGTGAGCTGGAGCA
ACAAGTGGTAGATTTGGAAGAAGAGAACCAAAAGCTTTTGCTAGAAAATCAGCTTTTACGAGAG
AAAACACATGGCCTTGTAGTTGAGAACCAGGAGTTAAGACAGCGCTTGGGGATGGATGCCTTAG
TTACTGAAGAGGAGGCAGAGACCAAGGGGAATGGAGCGGGGCCGGTGGCCGGGTCTGCTGAGTC
CGCAGCAGGTGCAGGCCCAGTTGTCACCCCTCCAGAACATCTCCCCATGGATTCTGACGGTGTT
GACTCTTCAGACTCTGAGTCTGATATCCTCTTGGGCATTCTGTTCAACTTGGACCCAGTCATGT
TCTTCAGATGTCCTTCCCCAGACTCTGCCAGCCTGGAGCAGCTCCCAGAAGTCGACCCAGAAGG
ACCCAGTTCCTTACCAGCCTCCCCTTCTTCATCACTGGGGACGTCACCAGCCAAGCTGGAAGCC
ATTAATGAAGTGATTCGTTTTGACCACGTATATACAAAGCCCCTAGTCTTAGAGATTCCCTCTG
AGACAGAGAGCCAAGCTAATGTGGTAGTGAAAATTGAGGAAGCACCTTCCAGCCCCTCAGAGAA
AGATCGCCCTGAATTCACTGTCTCAGTGAAGGAAGAACTTACAGAAGATGACTTCATTCCAGAG
CTGGGTATCTCAGATCTGCTTTCAACCAGCCACTGCCTAAAGCCATCTTCCTGCCTACTGGATG
CTTATAGTGACTGTAGCTATGAGGGTTCCCCTTCTCCCCTAAGTGACATGTCCTCTCTGCTTGG
TGTAGACCATTCGTGGGAGGACACTTTTGCCAGTGAACTCTTTCCCCAGCTGATTAGTGTCTAA
GGAGTGATCAGTACTGTTAACCCTTTTTCTTGACTATTACACTGCCTGGAGGATAGCACAGAAG
CCTGTGGTTCATTCAGAAAGCTAGAGTAGAGGGTGTACAGTCCTAGAGTATTCCTCTAATATAT
TTGTTCAAACCTCATAGGTCACCCCAGGTATTGTCTTTTGACATTCAGTGGTCTAGGACATGCA
GGTTGTTACTATAATCCAGAATTATGGCTTCTGAGGTACCTTTATCTTAAGGGCAGTGGTTTGC
CCTAAAATACTTGGGTAAGGGTCACTGGACAAGTGTCCTAGACATGGAATTAATGAATGGCCCT
TTATCATTTCTCTTCACCCCTTCTTGGCATCCCAGGCTTGCCTCTGATTTTAGGTCCTTTAGTT
TGCTTCTGCAGGCAGAGAGAATGCCTACCTGAGGGGGCTCCTTTTCCTTCATGTACAGTTCAAG
TAAAGATCAAGAATCTTTTGTGAAATTATTGAAATTTACTATGTAAATGCTTCACAGAATCTTT
CCCAGCTAGTGTAACTTTTGGAAGGTGCTTTCTCCATTTATTTAAAACTACCTGTGCAATTAAA
AAAAAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001136308	(Get FASTA)	NCBI Sequence Viewer
	NP_001258667	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACJ67898	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000048871
	ENSSSCP00000048871.3
	ENSSSCP00000056167
	ENSSSCP00000056167.2
	ENSSSCP00015040065.1
	ENSSSCP00015040129.1
	ENSSSCP00025023193.1
	ENSSSCP00025023224.1
	ENSSSCP00025023258.1
	ENSSSCP00030021247.1
	ENSSSCP00035014884.1
	ENSSSCP00040001478.1
	ENSSSCP00040001486.1
	ENSSSCP00045047436.1
	ENSSSCP00050045728.1
	ENSSSCP00055039065.1
	ENSSSCP00055039110.1
	ENSSSCP00055039177.1
	ENSSSCP00060047994.1
	ENSSSCP00065026212.1
	ENSSSCP00065026213.1
	ENSSSCP00065026217.1
	ENSSSCP00070040437.1

RefSeq Acc Id:	NP_001258667 ⟸ NM_001271738
- Peptide Label:	isoform XBP1(S)
- UniProtKB:	A0A8D0Q1G1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVVVAAAQSPTAGAPKVLLLSGKPAAAAAAGAPAGRALPIMVPGQRGASPEAASGGPPQTRKRQ RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGL VVENQELRQRLGMDALVTEEEAETKGNGAGPVAGSAESAAGAGPVVTPPEHLPMDSDGVDSSDS ESDILLGILFNLDPVMFFRCPSPDSASLEQLPEVDPEGPSSLPASPSSSLGTSPAKLEAINEVI RFDHVYTKPLVLEIPSETESQANVVVKIEEAPSSPSEKDRPEFTVSVKEELTEDDFIPELGISD LLSTSHCLKPSSCLLDAYSDCSYEGSPSPLSDMSSLLGVDHSWEDTFASELFPQLISV hide sequence

RefSeq Acc Id:	NP_001136308 ⟸ NM_001142836
- Peptide Label:	isoform XBP1(U)
- UniProtKB:	B7THW4 (UniProtKB/TrEMBL), A0A287BJ37 (UniProtKB/TrEMBL), A0A8D1YSM9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVVVAAAQSPTAGAPKVLLLSGKPAAAAAAGAPAGRALPIMVPGQRGASPEAASGGPPQTRKRQ RLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGL VVENQELRQRLGMDALVTEEEAETKGNGAGPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWI LTVLTLQTLSLISSWAFCSTWTQSCSSDVLPQTLPAWSSSQKSTQKDPVPYQPPLLHHWGRHQP SWKPLMK hide sequence

RefSeq Acc Id:

ENSSSCP00000030251 ⟸ ENSSSCT00000035419

RefSeq Acc Id:

ENSSSCP00000048871 ⟸ ENSSSCT00000047245

RefSeq Acc Id:

ENSSSCP00000056167 ⟸ ENSSSCT00000043460

Protein Domains

bZIP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000030996	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015072509	UniProtKB/TrEMBL
	ENSSSCG00025040003	UniProtKB/TrEMBL
	ENSSSCG00030034055	UniProtKB/TrEMBL
	ENSSSCG00035028216	UniProtKB/TrEMBL
	ENSSSCG00040003547	UniProtKB/TrEMBL
	ENSSSCG00045038498	UniProtKB/TrEMBL
	ENSSSCG00050076025	UniProtKB/TrEMBL
	ENSSSCG00055024781	UniProtKB/TrEMBL
	ENSSSCG00060078225	UniProtKB/TrEMBL
	ENSSSCG00065044251	UniProtKB/TrEMBL
	ENSSSCG00070024016	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000043460	ENTREZGENE
	ENSSSCT00000043460.3	UniProtKB/TrEMBL
	ENSSSCT00000047245	ENTREZGENE
	ENSSSCT00000047245.3	UniProtKB/TrEMBL
	ENSSSCT00015097481.1	UniProtKB/TrEMBL
	ENSSSCT00015097647.1	UniProtKB/TrEMBL
	ENSSSCT00025054467.1	UniProtKB/TrEMBL
	ENSSSCT00025054555.1	UniProtKB/TrEMBL
	ENSSSCT00025054661.1	UniProtKB/TrEMBL
	ENSSSCT00030047152.1	UniProtKB/TrEMBL
	ENSSSCT00035037334.1	UniProtKB/TrEMBL
	ENSSSCT00040004567.1	UniProtKB/TrEMBL
	ENSSSCT00040004584.1	UniProtKB/TrEMBL
	ENSSSCT00045066823.1	UniProtKB/TrEMBL
	ENSSSCT00050104342.1	UniProtKB/TrEMBL
	ENSSSCT00055048932.1	UniProtKB/TrEMBL
	ENSSSCT00055048993.1	UniProtKB/TrEMBL
	ENSSSCT00055049068.1	UniProtKB/TrEMBL
	ENSSSCT00060107960.1	UniProtKB/TrEMBL
	ENSSSCT00065060523.1	UniProtKB/TrEMBL
	ENSSSCT00065060529.1	UniProtKB/TrEMBL
	ENSSSCT00065060536.1	UniProtKB/TrEMBL
	ENSSSCT00070047916.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
InterPro	bZIP	UniProtKB/TrEMBL
	bZIP_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100217386	UniProtKB/TrEMBL
NCBI Gene	XBP1	ENTREZGENE
PANTHER	BZIP DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	X-BOX BINDING PROTEIN 1	UniProtKB/TrEMBL
	X-BOX-BINDING PROTEIN 1	UniProtKB/TrEMBL
Pfam	bZIP_2	UniProtKB/TrEMBL
PROSITE	BZIP	UniProtKB/TrEMBL
	BZIP_BASIC	UniProtKB/TrEMBL
SMART	BRLZ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57959	UniProtKB/TrEMBL
UniProt	A0A287AY46_PIG	UniProtKB/TrEMBL
	A0A287BJ37	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1VBE5_PIG	UniProtKB/TrEMBL
	A0A8D0Q1G1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1YSM9	ENTREZGENE, UniProtKB/TrEMBL
	B7THW4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:94993	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

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Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)