SLA-7 (MHC class I antigen 7) - Rat Genome Database

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Gene: SLA-7 (MHC class I antigen 7) Sus scrofa
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Symbol: SLA-7
Name: MHC class I antigen 7
RGD ID: 14123454
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); beta-2-microglobulin binding (ortholog); peptide antigen binding (ortholog); INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class Ib (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class Ib (ortholog); negative regulation of natural killer cell cytokine production (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); megacolon (ortholog); FOUND IN cell surface (ortholog); early endosome membrane (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH resveratrol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: swine leukocyte antigen 7
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1723,634,731 - 23,638,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,613,977 - 27,618,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7p1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
resveratrol  (EXP)

References
Additional References at PubMed
PMID:11169259   PMID:14708575   PMID:14736397   PMID:15118849   PMID:21645289   PMID:21906102   PMID:30032202  


Genomics

Comparative Map Data
SLA-7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1723,634,731 - 23,638,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,613,977 - 27,618,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7p1.1NCBI
HLA-F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,723,434 - 29,738,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,722,775 - 29,738,528 (+)EnsemblGRCh38hg38GRCh38
GRCh37629,691,211 - 29,695,073 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,799,096 - 29,803,052 (+)NCBINCBI36Build 36hg18NCBI36
Build 34629,799,219 - 29,802,262NCBI
Celera631,294,546 - 31,298,502 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,494,781 - 29,498,733 (+)NCBIHuRef
CHM1_1629,693,239 - 29,697,195 (+)NCBICHM1_1
T2T-CHM13v2.0629,594,785 - 29,612,450 (+)NCBIT2T-CHM13v2.0
Gm7030
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,438,501 - 36,440,317 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,420,611 - 36,440,317 (-)EnsemblGRCm39 Ensembl
GRCm381736,127,609 - 36,129,425 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,109,719 - 36,129,425 (-)EnsemblGRCm38mm10GRCm38
MGSCv371736,264,554 - 36,266,370 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361735,734,700 - 35,737,468 (-)NCBIMGSCv36mm8
Cytogenetic Map17B1NCBI
cM Map1718.94NCBI
RT1-CE5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,407,880 - 3,484,130 (-)NCBIGRCr8
mRatBN7.2203,403,418 - 3,479,476 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx203,635,423 - 3,639,599 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_WKY_Bbb_1.0203,853,121 - 3,857,288 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,892,702 - 4,896,993 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,892,702 - 4,896,991 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,968,846 - 6,973,135 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,509,593 - 3,513,732NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map20p12NCBI
DLA-79
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11841,142,312 - 41,170,018 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1841,142,307 - 41,170,100 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1840,176,809 - 40,179,971 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01841,795,844 - 41,823,728 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1841,796,018 - 41,799,523 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11841,261,712 - 41,264,874 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01840,836,984 - 40,840,146 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01841,564,328 - 41,567,490 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in SLA-7
145 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_213768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005665788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013977626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021098282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ251914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK395227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY463541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU467793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01074462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU322918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU322919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU322920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ224544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ224545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ224546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ224547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z97395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NM_213768   ⟹   NP_998933
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1723,635,488 - 23,638,441 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005665788   ⟹   XP_005665845
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1723,634,731 - 23,638,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013977626   ⟹   XP_013833080
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1723,634,731 - 23,638,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098282   ⟹   XP_020953941
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1723,634,731 - 23,638,722 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020953941   ⟸   XM_021098282
- Peptide Label: isoform X1
- UniProtKB: A0A8D2BK25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833080   ⟸   XM_013977626
- Peptide Label: isoform X3
- UniProtKB: A0A8D1JHW8 (UniProtKB/TrEMBL),   A0A8D0TTC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005665845   ⟸   XM_005665788
- Peptide Label: isoform X2
- UniProtKB: A0A8D1JHZ9 (UniProtKB/TrEMBL),   F1RZ57 (UniProtKB/TrEMBL),   A0A8D1S9M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_998933   ⟸   NM_213768
- Peptide Label: precursor
- UniProtKB: Q6S7D2 (UniProtKB/TrEMBL),   A0A8D1JLV4 (UniProtKB/TrEMBL)
- Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001398 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005030856 UniProtKB/TrEMBL
  ENSSSCG00025077759 UniProtKB/TrEMBL
  ENSSSCG00040071936 UniProtKB/TrEMBL
  ENSSSCG00045038292 UniProtKB/TrEMBL
  ENSSSCG00050005665 UniProtKB/TrEMBL
  ENSSSCG00055029263 UniProtKB/TrEMBL
  ENSSSCG00060041896 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001336 ENTREZGENE
  ENSSSCT00000001336.5 UniProtKB/TrEMBL
  ENSSSCT00000044197.3 UniProtKB/TrEMBL
  ENSSSCT00000084356.2 UniProtKB/TrEMBL
  ENSSSCT00005049358.1 UniProtKB/TrEMBL
  ENSSSCT00005049561.1 UniProtKB/TrEMBL
  ENSSSCT00005049585.1 UniProtKB/TrEMBL
  ENSSSCT00005049621.1 UniProtKB/TrEMBL
  ENSSSCT00005049762.1 UniProtKB/TrEMBL
  ENSSSCT00005050562.1 UniProtKB/TrEMBL
  ENSSSCT00005050632.1 UniProtKB/TrEMBL
  ENSSSCT00005050708.1 UniProtKB/TrEMBL
  ENSSSCT00005050760.1 UniProtKB/TrEMBL
  ENSSSCT00025108230.1 UniProtKB/TrEMBL
  ENSSSCT00025108231.1 UniProtKB/TrEMBL
  ENSSSCT00040100173.1 UniProtKB/TrEMBL
  ENSSSCT00040100391.1 UniProtKB/TrEMBL
  ENSSSCT00045066863.1 UniProtKB/TrEMBL
  ENSSSCT00045066926.1 UniProtKB/TrEMBL
  ENSSSCT00050007751.1 UniProtKB/TrEMBL
  ENSSSCT00055058864.1 UniProtKB/TrEMBL
  ENSSSCT00055058911.1 UniProtKB/TrEMBL
  ENSSSCT00060057049.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
KEGG Report ssc:396650 UniProtKB/TrEMBL
NCBI Gene SLA-7 ENTREZGENE
PANTHER CLASS IB MHC ANTIGEN QA-2-RELATED UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/TrEMBL
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF54452 UniProtKB/TrEMBL
UniProt A0A287BKQ8_PIG UniProtKB/TrEMBL
  A0A2S1PUJ1_PIG UniProtKB/TrEMBL
  A0A5G2R517_PIG UniProtKB/TrEMBL
  A0A8D0JMW7_PIG UniProtKB/TrEMBL
  A0A8D0JSJ1_PIG UniProtKB/TrEMBL
  A0A8D0JVE5_PIG UniProtKB/TrEMBL
  A0A8D0JX70_PIG UniProtKB/TrEMBL
  A0A8D0JXJ9_PIG UniProtKB/TrEMBL
  A0A8D0JYN7_PIG UniProtKB/TrEMBL
  A0A8D0LRU4_PIG UniProtKB/TrEMBL
  A0A8D0LS39_PIG UniProtKB/TrEMBL
  A0A8D0LSR5_PIG UniProtKB/TrEMBL
  A0A8D0TTC6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JHW8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JHZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JLV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1S9M0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2BK25 ENTREZGENE, UniProtKB/TrEMBL
  D4NVV4_PIG UniProtKB/TrEMBL
  D4NVV5_PIG UniProtKB/TrEMBL
  D4NVV6_PIG UniProtKB/TrEMBL
  F1RZ57 ENTREZGENE, UniProtKB/TrEMBL
  F8RU68_PIG UniProtKB/TrEMBL
  F8RU69_PIG UniProtKB/TrEMBL
  O19079_PIG UniProtKB/TrEMBL
  O19080_PIG UniProtKB/TrEMBL
  Q6S7D2 ENTREZGENE, UniProtKB/TrEMBL
  Q9TNZ2_PIG UniProtKB/TrEMBL