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Gene: URB1 (URB1 ribosome biogenesis homolog) Homo sapiens
Symbol: URB1
Name: URB1 ribosome biogenesis homolog
RGD ID: 1353651
Description: Exhibits RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Localizes to fibrillar center; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C21orf108; KIAA0539; NPA1; nucleolar pre-ribosomal-associated protein 1; nucleolar preribosomal-associated protein 1; nucleolar protein 254 kDa; URB1 ribosome biogenesis 1 homolog; URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Mus musculus (house mouse) : Urb1 (URB1 ribosome biogenesis 1 homolog (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Urb1 (URB1 ribosome biogenesis homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Urb1 (URB1 ribosome biogenesis homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : URB1 (URB1 ribosome biogenesis homolog)
Canis lupus familiaris (dog) : URB1 (URB1 ribosome biogenesis homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Urb1 (URB1 ribosome biogenesis homolog)
Sus scrofa (pig) : URB1 (URB1 ribosome biogenesis homolog)
Chlorocebus sabaeus (African green monkey) : URB1 (URB1 ribosome biogenesis homolog)
Heterocephalus glaber (naked mole-rat) : Urb1 (URB1 ribosome biogenesis homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2132,311,018 - 32,393,012 (-)EnsemblGRCh38hg38GRCh38
GRCh382132,311,018 - 32,393,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372133,683,330 - 33,765,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,683,330 - 33,765,312 (-)NCBINCBI36hg18NCBI36
Celera2118,866,931 - 18,948,939 (-)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2119,092,100 - 19,174,182 (-)NCBIHuRef
CHM1_12133,245,146 - 33,327,161 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on URB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353651
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.