Rbbp4 (retinoblastoma binding protein 4, chromatin remodeling factor) - Rat Genome Database

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Gene: Rbbp4 (retinoblastoma binding protein 4, chromatin remodeling factor) Mus musculus
Analyze
Symbol: Rbbp4
Name: retinoblastoma binding protein 4, chromatin remodeling factor
RGD ID: 1323350
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in DNA replication-dependent chromatin assembly; nucleosome assembly; and regulation of DNA-templated transcription. Predicted to act upstream of or within DNA replication and chromatin organization. Located in nucleus. Part of ESC/E(Z) complex and NuRD complex. Is expressed in several structures, including central nervous system; early conceptus; gonad; hemolymphoid system gland; and retina nuclear layer. Orthologous to human RBBP4 (RB binding protein 4, chromatin remodeling factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; chromatin assembly factor 1 subunit C; chromatin assembly factor I p48 subunit; histone-binding protein RBBP4; mRbAp48; nucleosome-remodeling factor subunit RBAP48; RBA; RBAP48; RBBP-4; retinoblastoma binding protein 4; retinoblastoma-binding protein 4; retinoblastoma-binding protein p48
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18593   Gm4800   Gm7200  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,200,893 - 129,229,163 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,200,893 - 129,229,163 (-)EnsemblGRCm39 Ensembl
GRCm384129,307,100 - 129,335,370 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,307,100 - 129,335,370 (-)EnsemblGRCm38mm10GRCm38
MGSCv374128,984,344 - 129,012,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,809,404 - 128,837,674 (-)NCBIMGSCv36mm8
Celera4127,647,840 - 127,676,109 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map463.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-vinylcyclohexene dioxide  (EXP)
5-fluorouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
cannabidiol  (ISO)
capecitabine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (EXP)
clobetasol  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
fenthion  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
menadione  (EXP)
methidathion  (EXP)
methoxychlor  (EXP)
miconazole  (EXP)
N-nitrosodiethylamine  (EXP)
nicotine  (EXP)
ochratoxin A  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
PhIP  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
pyrogallol  (EXP)
pyrrolidine dithiocarbamate  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
succimer  (EXP)
sulforaphane  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
trichloroethene  (EXP,ISO)
valproic acid  (ISO)
vincristine  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The nucleosome remodeling and deacetylase complex in development and disease. Basta J and Rauchman M, Transl Res. 2014 May 10. pii: S1931-5244(14)00166-2. doi: 10.1016/j.trsl.2014.05.003.
2. Age-associated alteration of gene expression patterns in mouse oocytes. Hamatani T, etal., Hum Mol Genet 2004 Oct 1;13(19):2263-78. Epub 2004 Aug 18.
3. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Hargreaves DC and Crabtree GR, Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1.
4. SET for life: biochemical activities and biological functions of SET domain-containing proteins. Herz HM, etal., Trends Biochem Sci. 2013 Dec;38(12):621-39. doi: 10.1016/j.tibs.2013.09.004. Epub 2013 Oct 20.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. Lagger G, etal., EMBO J 2002 Jun 3;21(11):2672-81.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
12. Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes. Yang J, etal., Genomics 2002 Oct;80(4):407-15.
Additional References at PubMed
PMID:7503932   PMID:7958874   PMID:9651585   PMID:9702189   PMID:10049565   PMID:10349636   PMID:10866654   PMID:10984530   PMID:11042159   PMID:11076861   PMID:11302704   PMID:11788710  
PMID:12477932   PMID:12520002   PMID:12904583   PMID:14609955   PMID:14610273   PMID:14645126   PMID:15226823   PMID:15920471   PMID:16141072   PMID:16141073   PMID:16428440   PMID:16581768  
PMID:17296600   PMID:18023262   PMID:18799693   PMID:19015307   PMID:19927129   PMID:20059953   PMID:20064376   PMID:20123894   PMID:20144788   PMID:20362541   PMID:20635899   PMID:20720167  
PMID:21267068   PMID:21589869   PMID:21677750   PMID:21873635   PMID:22325351   PMID:22354994   PMID:22438827   PMID:22560079   PMID:22770845   PMID:22865885   PMID:22984288   PMID:23180766  
PMID:23937658   PMID:23986399   PMID:25330109   PMID:25601759   PMID:25680957   PMID:25788661   PMID:26365490   PMID:26376479   PMID:26426291   PMID:27352031   PMID:28053041   PMID:28378742  
PMID:28554894   PMID:28712289   PMID:29459677   PMID:29795351   PMID:30026490   PMID:30196744   PMID:30355501   PMID:30457570   PMID:30595499   PMID:31077711   PMID:31138677   PMID:31162944  
PMID:31451685   PMID:32285100   PMID:32325033   PMID:33606987   PMID:34180153   PMID:35416979   PMID:35695185   PMID:36417873   PMID:37021556   PMID:38355793  


Genomics

Comparative Map Data
Rbbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,200,893 - 129,229,163 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,200,893 - 129,229,163 (-)EnsemblGRCm39 Ensembl
GRCm384129,307,100 - 129,335,370 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,307,100 - 129,335,370 (-)EnsemblGRCm38mm10GRCm38
MGSCv374128,984,344 - 129,012,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,809,404 - 128,837,674 (-)NCBIMGSCv36mm8
Celera4127,647,840 - 127,676,109 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map463.26NCBI
RBBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38132,651,208 - 32,686,211 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl132,651,142 - 32,686,211 (+)EnsemblGRCh38hg38GRCh38
GRCh37133,116,809 - 33,151,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36132,889,411 - 32,918,841 (+)NCBINCBI36Build 36hg18NCBI36
Build 34132,785,916 - 32,815,345NCBI
Celera131,385,428 - 31,420,582 (+)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,231,934 - 31,267,005 (+)NCBIHuRef
CHM1_1133,232,162 - 33,267,239 (+)NCBICHM1_1
T2T-CHM13v2.0132,510,988 - 32,546,003 (+)NCBIT2T-CHM13v2.0
Rbbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,940,207 - 146,959,501 (-)NCBIGRCr8
mRatBN7.25141,655,863 - 141,675,157 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,638,421 - 141,675,284 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5144,355,099 - 144,374,375 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05146,124,917 - 146,144,193 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05146,123,458 - 146,142,805 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05147,499,880 - 147,535,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,499,882 - 147,535,240 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,232,120 - 151,256,539 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,472,397 - 148,492,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15148,482,431 - 148,502,298 (-)NCBI
Celera5140,134,357 - 140,153,816 (-)NCBICelera
Cytogenetic Map5q36NCBI
Rbbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545210,955,399 - 10,975,036 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545210,955,399 - 10,975,036 (+)NCBIChiLan1.0ChiLan1.0
RBBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21194,138,913 - 194,168,532 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11193,261,113 - 193,290,737 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0131,944,257 - 31,974,763 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,111,234 - 33,146,184 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,111,234 - 33,140,518 (+)Ensemblpanpan1.1panPan2
RBBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,638,459 - 68,660,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,638,498 - 68,660,910 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha265,220,721 - 65,243,237 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,205,850 - 69,228,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl269,205,858 - 69,228,373 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,042,918 - 66,065,306 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,038,390 - 67,060,860 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,032,020 - 68,054,562 (-)NCBIUU_Cfam_GSD_1.0
Rbbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505849,767,432 - 49,786,599 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647415,592,240 - 15,611,381 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647415,592,226 - 15,611,381 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1688,987,092 - 89,006,815 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2682,938,419 - 83,033,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120100,191,259 - 100,220,608 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603316,468,914 - 16,498,674 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476415,800,143 - 15,823,319 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbbp4
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1161
Count of miRNA genes:619
Interacting mature miRNAs:769
Transcripts:ENSMUST00000102598, ENSMUST00000135585, ENSMUST00000140291, ENSMUST00000147183
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse

Markers in Region
UniSTS:225060  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384129,309,735 - 129,309,886UniSTSGRCm38
MGSCv374128,986,979 - 128,987,130UniSTSGRCm37
Celera4127,650,474 - 127,650,625UniSTS
Cytogenetic Map4D2.3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000102598   ⟹   ENSMUSP00000099658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,200,893 - 129,229,163 (-)Ensembl
GRCm38.p6 Ensembl4129,307,100 - 129,335,370 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135585   ⟹   ENSMUSP00000116517
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,222,442 - 129,228,876 (-)Ensembl
GRCm38.p6 Ensembl4129,328,649 - 129,335,083 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140291
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,203,310 - 129,228,437 (-)Ensembl
GRCm38.p6 Ensembl4129,309,517 - 129,334,644 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147183
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4129,218,617 - 129,229,042 (-)Ensembl
GRCm38.p6 Ensembl4129,324,824 - 129,335,249 (-)Ensembl
RefSeq Acc Id: NM_009030   ⟹   NP_033056
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394129,200,893 - 129,229,163 (-)NCBI
GRCm384129,307,100 - 129,335,370 (-)NCBI
MGSCv374128,984,344 - 129,012,614 (-)RGD
Celera4127,647,840 - 127,676,109 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033056   ⟸   NM_009030
- UniProtKB: A2A875 (UniProtKB/Swiss-Prot),   Q60972 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116517   ⟸   ENSMUST00000135585
RefSeq Acc Id: ENSMUSP00000099658   ⟸   ENSMUST00000102598
Protein Domains
Histone-binding protein RBBP4 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60972-F1-model_v2 AlphaFold Q60972 1-425 view protein structure

Promoters
RGD ID:6836034
Promoter ID:MM_KWN:39778
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000119480,   NM_009030,   OTTMUST00000022135,   OTTMUST00000022169,   OTTMUST00000022171,   OTTMUST00000022172,   OTTMUST00000041447,   OTTMUST00000068722
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364129,012,416 - 129,013,387 (-)MPROMDB
RGD ID:6884752
Promoter ID:EPDNEW_M5827
Type:initiation region
Name:Rbbp4_1
Description:Mus musculus retinoblastoma binding protein 4, chromatin remodelingfactor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384129,335,307 - 129,335,367EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1194912 AgrOrtholog
Ensembl Genes ENSMUSG00000057236 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000102598 ENTREZGENE
  ENSMUST00000102598.4 UniProtKB/Swiss-Prot
  ENSMUST00000135585.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  Histone-bd_RBBP4_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:19646 UniProtKB/Swiss-Prot
MGD MGI:1194912 ENTREZGENE
NCBI Gene 19646 ENTREZGENE
PANTHER HISTONE-BINDING PROTEIN RBBP4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 REPEAT FAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CAF1C_H4-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot
PhenoGen Rbbp4 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt A2A875 ENTREZGENE
  A8Y5E8_MOUSE UniProtKB/TrEMBL
  Q60972 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A2A875 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-14 Rbbp4  retinoblastoma binding protein 4, chromatin remodeling factor    retinoblastoma binding protein 4  Symbol and/or name change 5135510 APPROVED