Sall1 (spalt like transcription factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Sall1 (spalt like transcription factor 1) Mus musculus
Analyze
Symbol: Sall1
Name: spalt like transcription factor 1
RGD ID: 1320516
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of ectoderm development; nephron epithelium morphogenesis; and nervous system development. Acts upstream of or within several processes, including kidney development; limb morphogenesis; and nervous system development. Located in heterochromatin and nucleus. Part of NuRD complex. Is expressed in several structures, including autopod; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Used to study Townes-Brocks syndrome. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome; middle lobe syndrome; and renal Wilms' tumor. Orthologous to human SALL1 (spalt like transcription factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Msa; Msal-3; sal-3; sal-like 1; sal-like 1 (Drosophila); sal-like protein 1; zinc finger protein Spalt-3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39889,753,867 - 89,770,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl889,753,863 - 89,770,790 (-)EnsemblGRCm39 Ensembl
GRCm38889,027,242 - 89,044,162 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl889,027,235 - 89,044,162 (-)EnsemblGRCm38mm10GRCm38
MGSCv37891,551,141 - 91,568,061 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36891,918,348 - 91,932,544 (-)NCBIMGSCv36mm8
Celera893,321,670 - 93,338,514 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map843.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
choline  (EXP)
clobetasol  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dichloromethane  (EXP)
dicrotophos  (ISO)
dieldrin  (ISO)
dorsomorphin  (ISO)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
indometacin  (ISO)
inulin  (EXP)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
nefazodone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tamoxifen  (EXP,ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
zinc atom  (EXP)
zinc dichloride  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (ISO)
branching involved in ureteric bud morphogenesis  (IMP)
embryonic digestive tract development  (ISO)
embryonic digit morphogenesis  (IMP,ISO)
forelimb morphogenesis  (IGI)
GABAergic neuron differentiation  (IMP)
gonad development  (ISO)
heart development  (ISO)
hindlimb morphogenesis  (IGI)
inductive cell-cell signaling  (IMP)
kidney development  (ISO)
kidney epithelium development  (IMP)
limb development  (ISO)
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis  (IMP)
mesenchymal to epithelial transition involved in metanephros morphogenesis  (IMP)
negative regulation of DNA-templated transcription  (IDA,IMP,ISO)
negative regulation of ectoderm development  (IMP)
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis  (IMP)
negative regulation of mesoderm development  (IMP)
negative regulation of smoothened signaling pathway  (IGI)
negative regulation of transcription by RNA polymerase II  (IDA,IGI,IMP,ISO)
neural tube closure  (IGI)
neural tube development  (IGI)
neuron differentiation  (IMP)
olfactory bulb development  (IMP)
olfactory bulb interneuron differentiation  (IMP)
olfactory bulb mitral cell layer development  (ISO)
olfactory nerve development  (IMP)
pituitary gland development  (ISO)
positive regulation of branching involved in ureteric bud morphogenesis  (IMP)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of neuron differentiation  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
positive regulation of Wnt signaling pathway  (ISO)
regulation of neuroblast proliferation  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
smoothened signaling pathway  (IGI)
transcription by RNA polymerase II  (IMP)
ureteric bud development  (IMP)
ureteric bud invasion  (IMP)
ventricular septum development  (IGI,IMP)

Cellular Component
chromocenter  (ISO)
cytoplasm  (ISO)
heterochromatin  (IDA,ISO)
nucleoplasm  (TAS)
nucleus  (IBA,IC,IDA,ISO)
NuRD complex  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anus morphology  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal kidney cortex morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal kidney mesenchyme morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal metanephric mesenchyme morphology  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal rectum morphology  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal ureteric bud invasion  (IAGP)
abnormal ureteric bud morphology  (IAGP)
absent carpal bone  (IAGP)
absent kidney  (IAGP)
absent triquetrum  (IAGP)
absent ureter  (IAGP)
anal atresia  (IAGP)
anal stenosis  (IAGP)
conductive hearing loss  (IAGP)
deafness  (IAGP)
decreased cell proliferation  (IAGP)
dilated renal tubule  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
exencephaly  (IAGP)
fused metacarpal bones  (IAGP)
impaired branching involved in ureteric bud morphogenesis  (IAGP)
increased metanephric mesenchyme apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
intestinal obstruction  (IAGP)
kidney cyst  (IAGP)
metacarpal bone hypoplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
oligodactyly  (IAGP)
open neural tube  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
renal glomerulus atrophy  (IAGP)
renal hypoplasia  (IAGP)
renal tubular necrosis  (IAGP)
single kidney  (IAGP)
small kidney  (IAGP)
syndactyly  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. SALL1 mutation analysis in Townes-Brocks syndrome: twelve novel mutations and expansion of the phenotype. Botzenhart EM, etal., Hum Mutat. 2005 Sep;26(3):282.
2. SALL4 is a marker of the embryonal subtype of hepatoblastoma. Gnemmi V, etal., Histopathology. 2013 Sep;63(3):425-8. doi: 10.1111/his.12187. Epub 2013 Jul 3.
3. SALL1 mutations in Townes-Brocks syndrome and related disorders. Kohlhase J Hum Mutat. 2000 Dec;16(6):460-6.
4. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Metsuyanim S, etal., Stem Cells. 2008 Jul;26(7):1808-17. doi: 10.1634/stemcells.2007-0322. Epub 2008 May 8.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Nishinakamura R, etal., Development. 2001 Aug;128(16):3105-15. doi: 10.1242/dev.128.16.3105.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Therapeutic potential of human induced pluripotent stem cells and renal progenitor cells in experimental chronic kidney disease. Ribeiro PC, etal., Stem Cell Res Ther. 2020 Dec 9;11(1):530. doi: 10.1186/s13287-020-02060-4.
Additional References at PubMed
PMID:7671812   PMID:10965108   PMID:11231076   PMID:11404093   PMID:11836251   PMID:12466851   PMID:12477932   PMID:12482961   PMID:12520002   PMID:12590351   PMID:12783782   PMID:12915476  
PMID:14613977   PMID:15158448   PMID:15172686   PMID:15385616   PMID:15618518   PMID:16221172   PMID:16319116   PMID:16396903   PMID:16442091   PMID:16602821   PMID:16670092   PMID:16707490  
PMID:16790473   PMID:16839447   PMID:16916509   PMID:16919269   PMID:17036046   PMID:17060609   PMID:17093407   PMID:17295837   PMID:17300925   PMID:17537792   PMID:17967808   PMID:18024993  
PMID:18260139   PMID:18287559   PMID:18470945   PMID:18787044   PMID:18799693   PMID:18818376   PMID:19168674   PMID:19350679   PMID:19476507   PMID:19483677   PMID:19591821   PMID:19942929  
PMID:20053786   PMID:20127799   PMID:20159597   PMID:20362541   PMID:20362542   PMID:20412781   PMID:20439720   PMID:20702564   PMID:20843830   PMID:21062744   PMID:21267068   PMID:21345181  
PMID:21423180   PMID:21613322   PMID:21677750   PMID:21731673   PMID:21873635   PMID:21888672   PMID:21934330   PMID:22083510   PMID:22228756   PMID:22507837   PMID:23201013   PMID:23332759  
PMID:23555292   PMID:23825698   PMID:23892456   PMID:24218595   PMID:24370450   PMID:24398455   PMID:24440154   PMID:24500693   PMID:24550112   PMID:24742196   PMID:24744442   PMID:25142465  
PMID:25168025   PMID:25362053   PMID:25617721   PMID:25989023   PMID:26116661   PMID:26238476   PMID:26311113   PMID:26511275   PMID:26658320   PMID:26685160   PMID:26876450   PMID:27076431  
PMID:27210758   PMID:27459098   PMID:27471257   PMID:27480037   PMID:27654891   PMID:27776109   PMID:27820600   PMID:27974206   PMID:28759006   PMID:28760814   PMID:28847650   PMID:29109083  
PMID:29275859   PMID:29420474   PMID:29449451   PMID:29712641   PMID:29721946   PMID:29768210   PMID:29768498   PMID:29771971   PMID:29891551   PMID:30377232   PMID:30595499   PMID:30718617  
PMID:30886905   PMID:30905739   PMID:30929925   PMID:30943054   PMID:31061494   PMID:31077711   PMID:31142573   PMID:31762013   PMID:31785096   PMID:31813798   PMID:31862977   PMID:32259484  
PMID:32284604   PMID:32439942   PMID:32470397   PMID:32492250   PMID:32541832   PMID:32665241   PMID:32857879   PMID:33159702   PMID:33333014   PMID:33522362   PMID:33637522   PMID:33951437  
PMID:34255394   PMID:34321999   PMID:35451126   PMID:35567352   PMID:36228615   PMID:36465133   PMID:36527791   PMID:36747024   PMID:37185772   PMID:37196079   PMID:37322178   PMID:37519269  
PMID:38014633   PMID:38300866   PMID:38386912   PMID:38657443   PMID:38692273  


Genomics

Comparative Map Data
Sall1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39889,753,867 - 89,770,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl889,753,863 - 89,770,790 (-)EnsemblGRCm39 Ensembl
GRCm38889,027,242 - 89,044,162 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl889,027,235 - 89,044,162 (-)EnsemblGRCm38mm10GRCm38
MGSCv37891,551,141 - 91,568,061 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36891,918,348 - 91,932,544 (-)NCBIMGSCv36mm8
Celera893,321,670 - 93,338,514 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map843.51NCBI
SALL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381651,135,982 - 51,152,334 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1651,135,982 - 51,152,334 (-)EnsemblGRCh38hg38GRCh38
GRCh371651,169,893 - 51,185,181 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361649,727,387 - 49,742,684 (-)NCBINCBI36Build 36hg18NCBI36
Build 341649,727,829 - 49,742,653NCBI
Celera1635,686,254 - 35,701,557 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1637,057,983 - 37,073,288 (-)NCBIHuRef
CHM1_11652,577,216 - 52,592,517 (-)NCBICHM1_1
T2T-CHM13v2.01656,933,839 - 56,950,190 (-)NCBIT2T-CHM13v2.0
Sall1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81934,179,316 - 34,196,278 (+)NCBIGRCr8
mRatBN7.21918,005,782 - 18,022,705 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1918,007,503 - 18,022,705 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1919,687,226 - 19,702,424 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01924,881,820 - 24,897,018 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01927,838,998 - 27,854,185 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01923,387,737 - 23,405,025 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1923,389,375 - 23,405,039 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01934,377,838 - 34,395,131 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41919,277,337 - 19,293,298 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11919,283,733 - 19,298,618 (+)NCBI
Celera1917,896,753 - 17,911,869 (+)NCBICelera
Cytogenetic Map19p11NCBI
Sall1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554339,144,748 - 9,161,171 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554339,146,074 - 9,161,171 (-)NCBIChiLan1.0ChiLan1.0
SALL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21860,591,098 - 60,605,700 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11666,506,188 - 66,522,403 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01631,396,399 - 31,412,753 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11650,274,081 - 50,280,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1650,274,090 - 50,284,819 (-)Ensemblpanpan1.1panPan2
SALL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1264,242,742 - 64,260,021 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl264,243,987 - 64,259,521 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha260,816,127 - 60,833,504 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0264,787,008 - 64,804,401 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl264,787,375 - 64,804,352 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,612,959 - 61,630,321 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0262,631,291 - 62,648,633 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0263,519,257 - 63,536,638 (+)NCBIUU_Cfam_GSD_1.0
Sall1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934955,465,986 - 55,483,143 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364754,106,084 - 4,121,413 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364754,106,663 - 4,121,356 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SALL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl633,732,025 - 33,748,704 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1633,731,666 - 33,748,698 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2630,222,502 - 30,239,229 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SALL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1536,928,711 - 36,944,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl536,927,990 - 36,943,630 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604739,548,229 - 39,564,556 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sall1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247575,572,528 - 5,587,617 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247575,572,510 - 5,587,623 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sall1
641 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:262
Count of miRNA genes:216
Interacting mature miRNAs:233
Transcripts:ENSMUST00000034090
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined876411976110412125Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined876411976110412125Mouse
1301766Desp1_mdespair 1 (mouse)Not determined885486208119486373Mouse
1301253Skmw2_mskeletal muscle weight 2 (mouse)Not determined886443553120443701Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)882345783116345783Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879808806113809031Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined876411976110412125Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined872122809106123021Mouse
10045619Heal14_mwound healing/regeneration 14 (mouse)Not determined886443553120443701Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871829531105829637Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873929123107929226Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7158942790929226Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881819296115819296Mouse
1302049Heal1_mwound healing/regeneration 1 (mouse)Not determined886443553120443701Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889726628130027694Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined879245241113245331Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined876402145110402251Mouse

Markers in Region
UniSTS:235962  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38889,028,354 - 89,028,436UniSTSGRCm38
MGSCv37891,552,253 - 91,552,335UniSTSGRCm37
Celera893,322,782 - 93,322,864UniSTS
Cytogenetic Map8DUniSTS
PMC140661P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38889,028,096 - 89,028,383UniSTSGRCm38
MGSCv37891,551,995 - 91,552,282UniSTSGRCm37
Celera893,322,524 - 93,322,811UniSTS
Cytogenetic Map8DUniSTS
Sall1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8DUniSTS
cM Map8 UniSTS
RH47686  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381851,084,174 - 51,084,311UniSTSGRCm38
GRCm38889,027,320 - 89,027,459UniSTSGRCm38
MGSCv371851,243,828 - 51,243,965UniSTSGRCm37
MGSCv37891,551,219 - 91,551,358UniSTSGRCm37
Celera1852,402,615 - 52,402,752UniSTS
Celera893,321,748 - 93,321,887UniSTS
Cytogenetic Map8DUniSTS
AF021116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38889,032,952 - 89,033,113UniSTSGRCm38
MGSCv37891,556,851 - 91,557,012UniSTSGRCm37
Celera893,327,380 - 93,327,541UniSTS
Cytogenetic Map8DUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000034090   ⟹   ENSMUSP00000034090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl889,753,863 - 89,770,790 (-)Ensembl
GRCm38.p6 Ensembl889,027,235 - 89,044,162 (-)Ensembl
RefSeq Acc Id: NM_001371069   ⟹   NP_001357998
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39889,753,870 - 89,770,140 (-)NCBI
GRCm38889,027,242 - 89,043,512 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001371070   ⟹   NP_001357999
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39889,753,870 - 89,769,490 (-)NCBI
GRCm38889,027,242 - 89,042,862 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021390   ⟹   NP_067365
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39889,753,870 - 89,770,790 (-)NCBI
GRCm38889,027,242 - 89,044,162 (-)NCBI
MGSCv37891,551,141 - 91,568,061 (-)RGD
Celera893,321,670 - 93,338,514 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036154203   ⟹   XP_036010096
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39889,753,867 - 89,768,267 (-)NCBI
Sequence:
RefSeq Acc Id: NP_067365   ⟸   NM_021390
- UniProtKB: Q9ER74 (UniProtKB/Swiss-Prot),   Q920R5 (UniProtKB/Swiss-Prot),   Q6P5E3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001357998   ⟸   NM_001371069
- UniProtKB: Q9ER74 (UniProtKB/Swiss-Prot),   Q920R5 (UniProtKB/Swiss-Prot),   Q6P5E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001357999   ⟸   NM_001371070
- UniProtKB: Q9ER74 (UniProtKB/Swiss-Prot),   Q920R5 (UniProtKB/Swiss-Prot),   Q6P5E3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000034090   ⟸   ENSMUST00000034090
RefSeq Acc Id: XP_036010096   ⟸   XM_036154203
- Peptide Label: isoform X1
- UniProtKB: Q9EPW7 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ER74-F1-model_v2 AlphaFold Q9ER74 1-1322 view protein structure

Promoters
RGD ID:8667833
Promoter ID:EPDNEW_M11947
Type:multiple initiation site
Name:Sall1_2
Description:Mus musculus spalt like transcription factor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11948  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38889,042,456 - 89,042,516EPDNEW
RGD ID:8667835
Promoter ID:EPDNEW_M11948
Type:initiation region
Name:Sall1_1
Description:Mus musculus spalt like transcription factor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11947  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38889,044,183 - 89,044,243EPDNEW
RGD ID:6843689
Promoter ID:MM_KWN:55223
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:UC009MRZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36891,566,386 - 91,566,886 (-)MPROMDB
RGD ID:6843688
Promoter ID:MM_KWN:55224
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Liver
Transcripts:NM_021390
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36891,567,576 - 91,569,052 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1889585 AgrOrtholog
Ensembl Genes ENSMUSG00000031665 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034090 ENTREZGENE
  ENSMUST00000034090.8 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Sal_C2H2-zinc-finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1889585 ENTREZGENE
NCBI Gene 58198 ENTREZGENE
PANTHER SAL-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAL-LIKE PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sall1 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q6P5E3 ENTREZGENE, UniProtKB/TrEMBL
  Q920R5 ENTREZGENE
  Q9EPW7 ENTREZGENE, UniProtKB/TrEMBL
  Q9ER74 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q920R5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Sall1  spalt like transcription factor 1    sal-like 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED