Dnajc6 (DnaJ heat shock protein family (Hsp40) member C6) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dnajc6 (DnaJ heat shock protein family (Hsp40) member C6) Mus musculus
Analyze
Symbol: Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
RGD ID: 1320496
MGI Page MGI
Description: Predicted to enable clathrin heavy chain binding activity and heat shock protein binding activity. Involved in clathrin-dependent endocytosis and synaptic vesicle uncoating. Acts upstream of or within clathrin coat disassembly and regulation of clathrin-dependent endocytosis. Located in postsynaptic density. Is extrinsic component of presynaptic endocytic zone membrane. Is expressed in genital tubercle of male; gut; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 19A. Orthologous to human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810027M23Rik; au; auxilin; DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ (Hsp40) homolog, subfamily C, member 6; dnaJ homolog subfamily C member 6; mKIAA0473; putative tyrosine-protein phosphatase auxilin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,353,751 - 101,499,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,353,828 - 101,499,996 (+)EnsemblGRCm39 Ensembl
GRCm384101,496,648 - 101,642,799 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,496,631 - 101,642,799 (+)EnsemblGRCm38mm10GRCm38
MGSCv374101,169,253 - 101,315,404 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364101,048,526 - 101,140,731 (+)NCBIMGSCv36mm8
Celera499,840,177 - 99,986,461 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6MouseParkinson's disease  ISODNAJC6 (Homo sapiens)10450521 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6MouseCombined Cerebellar and Peripheral Ataxia with Hearing Loss and Diabetes Mellitus  ISODNAJC6 (Homo sapiens)8554872ClinVar Annotator: match by term: Ataxia more ...ClinVarPMID:2256350 more ...
Dnajc6Mousecongenital disorder of glycosylation It  ISODNAJC6 (Homo sapiens)8554872ClinVar Annotator: match by term: PGM1-congenital disorder of glycosylationClinVarPMID:28492532
Dnajc6Mousegenetic disease  ISODNAJC6 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Dnajc6Mouseintellectual disability  ISODNAJC6 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and severeClinVarPMID:25741868
Dnajc6MouseParkinson's disease 19A  ISODNAJC6 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:16199547 more ...
Dnajc6Mouseprostate cancer  ISODNAJC6 (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:22563501 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6Mousehepatocellular carcinoma  ISODNAJC6 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28284560
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6MouseParkinson's disease 19A  ISODNAJC6 (Homo sapiens)7240710 OMIM 

1 to 20 of 80 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6Mouse1,1-dichloroethene decreases expressionEXP 6480464vinylidene chloride results in decreased expression of DNAJC6 mRNACTDPMID:26682919
Dnajc6Mouse17beta-estradiol multiple interactionsISODnajc6 (Rattus norvegicus)6480464[bisphenol A co-treated with Estradiol] results in decreased expression of DNAJC6 mRNACTDPMID:26496021
Dnajc6Mouse17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of DNAJC6 mRNACTDPMID:39298647
Dnajc6Mouse17beta-estradiol multiple interactionsISODNAJC6 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of DNAJC6 mRNACTDPMID:30165855
Dnajc6Mouse2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsEXP 6480464[2 more ...CTDPMID:25510870
Dnajc6Mouse2,2',5,5'-tetrachlorobiphenyl multiple interactionsEXP 6480464[2 more ...CTDPMID:25510870
Dnajc6Mouse3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of DNAJC6 mRNACTDPMID:20188158
Dnajc6Mouse3-chloropropane-1,2-diol increases expressionISODnajc6 (Rattus norvegicus)6480464alpha-Chlorohydrin results in increased expression of DNAJC6 mRNACTDPMID:28522335
Dnajc6Mouse4,4'-sulfonyldiphenol increases methylationISODNAJC6 (Homo sapiens)6480464bisphenol S results in increased methylation of DNAJC6 geneCTDPMID:31601247
Dnajc6Mouse4,4'-sulfonyldiphenol multiple interactionsISODnajc6 (Rattus norvegicus)6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DNAJC6 mRNACTDPMID:36041667
Dnajc6Mouse4-hydroxyphenyl retinamide increases expressionEXP 6480464Fenretinide results in increased expression of DNAJC6 mRNACTDPMID:28973697
Dnajc6Mouse4-hydroxyphenyl retinamide decreases expressionEXP 6480464Fenretinide results in decreased expression of DNAJC6 mRNACTDPMID:28973697
Dnajc6Mousealpha-Zearalanol multiple interactionsISODnajc6 (Rattus norvegicus)6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of DNAJC6 mRNACTDPMID:35163327
Dnajc6Mouseantirheumatic drug decreases expressionISODNAJC6 (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of DNAJC6 mRNACTDPMID:24449571
Dnajc6Mousearsane affects methylationISODNAJC6 (Homo sapiens)6480464Arsenic affects the methylation of DNAJC6 geneCTDPMID:25304211
Dnajc6Mousearsenic atom affects methylationISODNAJC6 (Homo sapiens)6480464Arsenic affects the methylation of DNAJC6 geneCTDPMID:25304211
Dnajc6Mousearsenite(3-) increases methylationISODNAJC6 (Homo sapiens)6480464arsenite results in increased methylation of DNAJC6 promoterCTDPMID:23974009
Dnajc6Mousebenzo[a]pyrene decreases methylationISODNAJC6 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of DNAJC6 3' UTRCTDPMID:27901495
Dnajc6Mousebenzo[a]pyrene increases methylationISODNAJC6 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of DNAJC6 5' UTR and Benzo(a)pyrene results in increased methylation of DNAJC6 promoterCTDPMID:27901495
Dnajc6Mousebenzo[a]pyrene increases methylationEXP 6480464Benzo(a)pyrene results in increased methylation of DNAJC6 intronCTDPMID:27901495

1 to 20 of 80 rows

Biological Process
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6Mousechromatin remodeling involved_inIEAGO:01407932290270 GOCGO_REF:0000108
Dnajc6Mouseclathrin coat disassembly acts_upstream_of_or_withinIMPMGI:44404892290270 PMID:20160091MGIPMID:20160091
Dnajc6Mouseclathrin coat disassembly involved_inISSUniProtKB:Q279742290270 UniProtGO_REF:0000024
Dnajc6Mouseclathrin coat disassembly acts_upstream_of_or_withinIGIMGI:1053842290270 PMID:20160091MGIPMID:20160091
Dnajc6Mouseclathrin-dependent endocytosis involved_inIDA 2290270 PMID:20160091UniProtPMID:20160091
Dnajc6Mouseclathrin-dependent endocytosis involved_inISOUniProtKB:O750612290270 GO_CentralGO_REF:0000119
Dnajc6Mouseclathrin-dependent endocytosis involved_inIBAPANTHER:PTN000571055 more ...2290270 GO_CentralGO_REF:0000033
Dnajc6Mouseintracellular transport involved_inISSUniProtKB:O750612290270 UniProtGO_REF:0000024
Dnajc6Mouseintracellular transport involved_inISOUniProtKB:O750612290270 GO_CentralGO_REF:0000119
Dnajc6Mouseregulation of clathrin coat assembly involved_inISOUniProtKB:O750612290270 GO_CentralGO_REF:0000119
Dnajc6Mouseregulation of clathrin coat assembly involved_inISSUniProtKB:O750612290270 UniProtGO_REF:0000024
Dnajc6Mouseregulation of clathrin-dependent endocytosis acts_upstream_of_or_withinIMPMGI:44404892290270 PMID:20160091MGIPMID:20160091
Dnajc6Mousesynaptic vesicle recycling involved_inIMP 2290270 PMID:20160091UniProtPMID:20160091
Dnajc6Mousesynaptic vesicle uncoating involved_inIDA 2290270 PMID:20160091SynGOPMID:20160091
Dnajc6Mousesynaptic vesicle uncoating involved_inIBAPANTHER:PTN002753975 and MGI:19199352290270 GO_CentralGO_REF:0000033
Dnajc6Mousesynaptic vesicle uncoating involved_inIMP 2290270 PMID:20160091SynGOPMID:20160091
1 to 16 of 16 rows

Cellular Component
1 to 9 of 9 rows

  
1 to 9 of 9 rows

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6Mouseclathrin binding enablesISSUniProtKB:Q279742290270 UniProtGO_REF:0000024
Dnajc6Mouseclathrin binding enablesIBAPANTHER:PTN000571055 more ...2290270 GO_CentralGO_REF:0000033
Dnajc6Mouseclathrin heavy chain binding enablesISSUniProtKB:Q279742290270 UniProtGO_REF:0000024
Dnajc6Mouseheat shock protein binding enablesISSUniProtKB:Q279742290270 UniProtGO_REF:0000024
Dnajc6Mousehistone H2AXY142 phosphatase activity enablesIEAEC:3.1.3.482290270 UniProtGO_REF:0000003
Dnajc6Mousenon-membrane spanning protein tyrosine phosphatase activity enablesIEAEC:3.1.3.482290270 UniProtGO_REF:0000003
Dnajc6Mouseprotein binding enablesISOUniProtKB:Q006109068941 PMID:29735704UniProtPMID:29735704
Dnajc6Mouseprotein tyrosine phosphatase activity, metal-dependent enablesIEAEC:3.1.3.482290270 UniProtGO_REF:0000003
Dnajc6MouseSH3 domain binding enablesIEAUniProtKB-KW:KW-07292290270 UniProtGO_REF:0000043
1 to 9 of 9 rows

RGD Manual Annotations


  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnajc6Mouseendocytosis pathway  IEA 6907045 KEGGmmu:04144

1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. Synaptojanin 1 mutation in Parkinson's disease brings further insight into the neuropathological mechanisms. Drouet V and Lesage S, Biomed Res Int. 2014;2014:289728. doi: 10.1155/2014/289728. Epub 2014 Sep 16.
2. Impaired intracellular trafficking defines early Parkinson's disease. Hunn BH, etal., Trends Neurosci. 2015 Mar;38(3):178-88. doi: 10.1016/j.tins.2014.12.009. Epub 2015 Jan 29.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
1 to 12 of 12 rows
PMID:8889548   PMID:10349636   PMID:10512203   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12819125   PMID:12904583   PMID:15489334   PMID:15840001   PMID:16141072   PMID:16141073  
PMID:17114649   PMID:17967808   PMID:18434600   PMID:18554416   PMID:18799693   PMID:20160091   PMID:21267068   PMID:21873635   PMID:27507650   PMID:28671696   PMID:29111324   PMID:29652249  
PMID:30562941   PMID:32325033   PMID:34321999   PMID:35456010   PMID:36792618   PMID:36920906   PMID:37142655   PMID:37331165   PMID:37766983   PMID:38355793   PMID:39885289  



Dnajc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,353,751 - 101,499,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,353,828 - 101,499,996 (+)EnsemblGRCm39 Ensembl
GRCm384101,496,648 - 101,642,799 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,496,631 - 101,642,799 (+)EnsemblGRCm38mm10GRCm38
MGSCv374101,169,253 - 101,315,404 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364101,048,526 - 101,140,731 (+)NCBIMGSCv36mm8
Celera499,840,177 - 99,986,461 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.89NCBI
DNAJC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38165,264,749 - 65,415,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl165,248,219 - 65,415,871 (+)EnsemblGRCh38hg38GRCh38
GRCh37165,730,432 - 65,881,554 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36165,503,018 - 65,654,140 (+)NCBINCBI36Build 36hg18NCBI36
Build 34165,442,450 - 65,593,573NCBI
Celera164,021,163 - 64,172,220 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef163,839,137 - 63,990,340 (+)NCBIHuRef
CHM1_1165,846,654 - 65,997,823 (+)NCBICHM1_1
T2T-CHM13v2.0165,142,745 - 65,293,848 (+)NCBIT2T-CHM13v2.0
Dnajc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,232,532 - 121,398,775 (+)NCBIGRCr8
mRatBN7.25116,120,069 - 116,283,448 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5116,119,676 - 116,283,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,690,704 - 118,836,807 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,416,048 - 120,562,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,467,359 - 120,613,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,330,372 - 120,492,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,340,646 - 120,492,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,210,621 - 124,370,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,155,150 - 122,309,090 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15122,205,852 - 122,314,329 (+)NCBI
Celera5114,661,979 - 114,806,295 (+)NCBICelera
Cytogenetic Map5q33NCBI
Dnajc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542325,269,466 - 25,377,641 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542325,269,459 - 25,382,664 (-)NCBIChiLan1.0ChiLan1.0
DNAJC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21161,446,599 - 161,607,811 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,597,432 - 160,758,627 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0164,501,805 - 64,662,999 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1166,389,807 - 66,550,886 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl166,399,968 - 66,550,879 (+)Ensemblpanpan1.1panPan2
DNAJC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1544,882,111 - 45,021,152 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl544,884,283 - 45,120,203 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha544,938,863 - 45,077,971 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0545,062,677 - 45,201,688 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl545,061,729 - 45,201,677 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1545,028,100 - 45,167,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0544,972,606 - 45,111,645 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0545,223,560 - 45,362,686 (-)NCBIUU_Cfam_GSD_1.0
Dnajc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505878,372,295 - 78,520,601 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366922,741,632 - 2,834,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366922,788,477 - 2,836,094 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6146,989,351 - 147,155,131 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16146,990,115 - 147,161,010 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26135,395,465 - 135,566,139 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12067,661,187 - 67,824,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2067,660,680 - 67,809,086 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603349,732,881 - 49,896,207 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474229,398,544 - 29,485,165 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474229,397,811 - 29,525,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dnajc6
8058 total Variants

Predicted Target Of
Summary Value
Count of predictions:7632
Count of miRNA genes:731
Interacting mature miRNAs:990
Transcripts:ENSMUST00000038207, ENSMUST00000094953, ENSMUST00000106929, ENSMUST00000106930, ENSMUST00000106933, ENSMUST00000146489, ENSMUST00000149047, ENSMUST00000154120
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 81 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
27226782Tibl2_mtibia length 2, 5 week (mouse)490888237111257197Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
11532708Sluc43i_msusceptibility to lung cancer 43i (mouse)474444699108444983Mouse
11532707Sluc43h_msusceptibility to lung cancer 43h (mouse)474444699108444983Mouse
11532706Sluc43c_msusceptibility to lung cancer 43c (mouse)474444699108444983Mouse

1 to 10 of 81 rows
BF393615  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384101,628,620 - 101,628,792UniSTSGRCm38
MGSCv374101,301,225 - 101,301,397UniSTSGRCm37
Celera499,972,282 - 99,972,454UniSTS
Cytogenetic Map4C6UniSTS






1 to 27 of 27 rows
RefSeq Transcripts NM_001164583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK012831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY008260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ175337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX323551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY150950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY273493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY773492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ111757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 27 of 27 rows

Ensembl Acc Id: ENSMUST00000038207   ⟹   ENSMUSP00000044251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,365,068 - 101,499,996 (+)Ensembl
GRCm38.p6 Ensembl4101,507,871 - 101,642,799 (+)Ensembl
Ensembl Acc Id: ENSMUST00000094953   ⟹   ENSMUSP00000092560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,407,677 - 101,499,996 (+)Ensembl
GRCm38.p6 Ensembl4101,550,480 - 101,642,799 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106929   ⟹   ENSMUSP00000102542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,365,197 - 101,499,995 (+)Ensembl
GRCm38.p6 Ensembl4101,508,000 - 101,642,798 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106930   ⟹   ENSMUSP00000102543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,353,845 - 101,499,996 (+)Ensembl
GRCm38.p6 Ensembl4101,496,648 - 101,642,799 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106933   ⟹   ENSMUSP00000102546
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,407,791 - 101,499,979 (+)Ensembl
GRCm38.p6 Ensembl4101,550,594 - 101,642,782 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146489
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,365,227 - 101,456,301 (+)Ensembl
GRCm38.p6 Ensembl4101,508,030 - 101,599,104 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149047   ⟹   ENSMUSP00000119542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,365,173 - 101,468,548 (+)Ensembl
GRCm38.p6 Ensembl4101,507,976 - 101,611,351 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154120   ⟹   ENSMUSP00000114840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4101,353,828 - 101,475,751 (+)Ensembl
GRCm38.p6 Ensembl4101,496,631 - 101,618,554 (+)Ensembl
RefSeq Acc Id: NM_001164583   ⟹   NP_001158055
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,407,506 - 101,499,996 (+)NCBI
GRCm384101,550,594 - 101,642,799 (+)NCBI
MGSCv374101,169,253 - 101,315,404 (+)RGD
Celera499,840,177 - 99,986,461 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164584   ⟹   NP_001158056
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,365,176 - 101,499,996 (+)NCBI
GRCm384101,507,976 - 101,642,799 (+)NCBI
MGSCv374101,169,253 - 101,315,404 (+)RGD
Celera499,840,177 - 99,986,461 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164585   ⟹   NP_001158057
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,365,176 - 101,499,996 (+)NCBI
GRCm384101,507,976 - 101,642,799 (+)NCBI
MGSCv374101,169,253 - 101,315,404 (+)RGD
Celera499,840,177 - 99,986,461 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001355179   ⟹   NP_001342108
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,353,751 - 101,499,996 (+)NCBI
GRCm384101,496,648 - 101,642,799 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001355180   ⟹   NP_001342109
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,365,176 - 101,499,996 (+)NCBI
GRCm384101,507,976 - 101,642,799 (+)NCBI
Sequence:
RefSeq Acc Id: NM_198412   ⟹   NP_940804
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394101,353,751 - 101,499,996 (+)NCBI
GRCm384101,496,648 - 101,642,799 (+)NCBI
MGSCv374101,169,253 - 101,315,404 (+)RGD
Celera499,840,177 - 99,986,461 (+)RGD
cM Map4 ENTREZGENE
Sequence:
1 to 5 of 13 rows
1 to 5 of 13 rows
RefSeq Acc Id: NP_940804   ⟸   NM_198412
- Peptide Label: isoform c
- UniProtKB: Q80TZ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158057   ⟸   NM_001164585
- Peptide Label: isoform c
- UniProtKB: Q80TZ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158056   ⟸   NM_001164584
- Peptide Label: isoform b
- UniProtKB: Q6P2K9 (UniProtKB/Swiss-Prot),   B1B0B9 (UniProtKB/Swiss-Prot),   Q8C7L9 (UniProtKB/Swiss-Prot),   Q80TZ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158055   ⟸   NM_001164583
- Peptide Label: isoform a
- UniProtKB: Q80TZ3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001342108   ⟸   NM_001355179
- Peptide Label: isoform d
Name Modeler Protein Id AA Range Protein Structure
AF-Q80TZ3-F1-model_v2 AlphaFold Q80TZ3 1-938 view protein structure

RGD ID:6883970
Promoter ID:EPDNEW_M5436
Type:initiation region
Name:Dnajc6_2
Description:Mus musculus DnaJ heat shock protein family member C6 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5438  EPDNEW_M5437  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,496,551 - 101,496,611EPDNEW
RGD ID:6883996
Promoter ID:EPDNEW_M5437
Type:initiation region
Name:Dnajc6_3
Description:Mus musculus DnaJ heat shock protein family member C6 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5436  EPDNEW_M5438  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,507,996 - 101,508,056EPDNEW
RGD ID:6883974
Promoter ID:EPDNEW_M5438
Type:single initiation site
Name:Dnajc6_1
Description:Mus musculus DnaJ heat shock protein family member C6 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5436  EPDNEW_M5437  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384101,562,005 - 101,562,065EPDNEW


1 to 40 of 46 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000028528 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038207 ENTREZGENE
  ENSMUST00000038207.12 UniProtKB/Swiss-Prot
  ENSMUST00000094953.11 UniProtKB/Swiss-Prot
  ENSMUST00000106929 ENTREZGENE
  ENSMUST00000106929.10 UniProtKB/Swiss-Prot
  ENSMUST00000106930 ENTREZGENE
  ENSMUST00000106930.8 UniProtKB/Swiss-Prot
  ENSMUST00000106933 ENTREZGENE
  ENSMUST00000106933.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot
  2.60.40.1110 UniProtKB/Swiss-Prot
  3.90.190.10 UniProtKB/Swiss-Prot
InterPro C2_domain_sf UniProtKB/Swiss-Prot
  DnaJ_domain UniProtKB/Swiss-Prot
  J_dom_sf UniProtKB/Swiss-Prot
  Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot
  Tensin_C2-dom UniProtKB/Swiss-Prot
  Tensin_phosphatase UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot
KEGG Report mmu:72685 UniProtKB/Swiss-Prot
MGD MGI:1919935 ENTREZGENE
NCBI Gene 72685 ENTREZGENE
PANTHER AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED UniProtKB/Swiss-Prot
  TYROSINE-PROTEIN PHOSPHATASE AUXILIN-RELATED UniProtKB/Swiss-Prot
Pfam PTEN_C2 UniProtKB/Swiss-Prot
PhenoGen Dnajc6 PhenoGen
PROSITE C2_TENSIN UniProtKB/Swiss-Prot
  DNAJ_2 UniProtKB/Swiss-Prot
  PPASE_TENSIN UniProtKB/Swiss-Prot
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot
SMART DnaJ UniProtKB/Swiss-Prot
  PTEN_C2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot
  SSF49562 UniProtKB/Swiss-Prot
  SSF52799 UniProtKB/Swiss-Prot
UniProt AUXI_MOUSE UniProtKB/Swiss-Prot
  B1B0B7_MOUSE UniProtKB/TrEMBL
  B1B0B8_MOUSE UniProtKB/TrEMBL
  B1B0B9 ENTREZGENE
1 to 40 of 46 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 Dnajc6  DnaJ heat shock protein family (Hsp40) member C6    DnaJ (Hsp40) homolog, subfamily C, member 6  Symbol and/or name change 5135510 APPROVED