Dnajc6 (DnaJ heat shock protein family (Hsp40) member C6) - Rat Genome Database

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Gene: Dnajc6 (DnaJ heat shock protein family (Hsp40) member C6) Rattus norvegicus
Analyze
Symbol: Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
RGD ID: 1309900
Description: Predicted to be involved in endocytosis; intracellular transport; and regulation of clathrin coat assembly. Predicted to act upstream of or within clathrin coat disassembly and regulation of clathrin-dependent endocytosis. Predicted to be located in postsynaptic density. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 19A. Orthologous to human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6); PARTICIPATES IN altered clathrin-dependent synaptic vesicle endocytosis; clathrin-dependent synaptic vesicle endocytosis; Parkinson's disease pathway; INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DnaJ (Hsp40) homolog, subfamily C, member 6; LOC313409; putative tyrosine-protein phosphatase auxilin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,232,532 - 121,398,775 (+)NCBIGRCr8
mRatBN7.25116,120,069 - 116,283,448 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5116,119,676 - 116,283,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,690,704 - 118,836,807 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,416,048 - 120,562,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,467,359 - 120,613,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,330,372 - 120,492,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,340,646 - 120,492,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,210,621 - 124,370,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,155,150 - 122,309,090 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15122,205,852 - 122,314,329 (+)NCBI
Celera5114,661,979 - 114,806,295 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Synaptojanin 1 mutation in Parkinson's disease brings further insight into the neuropathological mechanisms. Drouet V and Lesage S, Biomed Res Int. 2014;2014:289728. doi: 10.1155/2014/289728. Epub 2014 Sep 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Impaired intracellular trafficking defines early Parkinson's disease. Hunn BH, etal., Trends Neurosci. 2015 Mar;38(3):178-88. doi: 10.1016/j.tins.2014.12.009. Epub 2015 Jan 29.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
Additional References at PubMed
PMID:16262722   PMID:17114649   PMID:20160091   PMID:21482805   PMID:22393045  


Genomics

Comparative Map Data
Dnajc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85121,232,532 - 121,398,775 (+)NCBIGRCr8
mRatBN7.25116,120,069 - 116,283,448 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5116,119,676 - 116,283,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5118,690,704 - 118,836,807 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05120,416,048 - 120,562,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05120,467,359 - 120,613,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05120,330,372 - 120,492,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5120,340,646 - 120,492,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05124,210,621 - 124,370,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45122,155,150 - 122,309,090 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15122,205,852 - 122,314,329 (+)NCBI
Celera5114,661,979 - 114,806,295 (+)NCBICelera
Cytogenetic Map5q33NCBI
DNAJC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38165,264,749 - 65,415,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl165,248,219 - 65,415,871 (+)EnsemblGRCh38hg38GRCh38
GRCh37165,730,432 - 65,881,554 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36165,503,018 - 65,654,140 (+)NCBINCBI36Build 36hg18NCBI36
Build 34165,442,450 - 65,593,573NCBI
Celera164,021,163 - 64,172,220 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef163,839,137 - 63,990,340 (+)NCBIHuRef
CHM1_1165,846,654 - 65,997,823 (+)NCBICHM1_1
T2T-CHM13v2.0165,142,745 - 65,293,848 (+)NCBIT2T-CHM13v2.0
Dnajc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394101,353,751 - 101,499,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4101,353,828 - 101,499,996 (+)EnsemblGRCm39 Ensembl
GRCm384101,496,648 - 101,642,799 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4101,496,631 - 101,642,799 (+)EnsemblGRCm38mm10GRCm38
MGSCv374101,169,253 - 101,315,404 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364101,048,526 - 101,140,731 (+)NCBIMGSCv36mm8
Celera499,840,177 - 99,986,461 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map446.89NCBI
Dnajc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542325,269,466 - 25,377,641 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542325,269,459 - 25,382,664 (-)NCBIChiLan1.0ChiLan1.0
DNAJC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21161,446,599 - 161,607,811 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,597,432 - 160,758,627 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0164,501,805 - 64,662,999 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1166,389,807 - 66,550,886 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl166,399,968 - 66,550,879 (+)Ensemblpanpan1.1panPan2
DNAJC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1544,882,111 - 45,021,152 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl544,884,283 - 45,120,203 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha544,938,863 - 45,077,971 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0545,062,677 - 45,201,688 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl545,061,729 - 45,201,677 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1545,028,100 - 45,167,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0544,972,606 - 45,111,645 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0545,223,560 - 45,362,686 (-)NCBIUU_Cfam_GSD_1.0
Dnajc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505878,372,295 - 78,520,601 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366922,741,632 - 2,834,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366922,788,477 - 2,836,094 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6146,989,351 - 147,155,131 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16146,990,115 - 147,161,010 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26135,395,465 - 135,566,139 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12067,661,187 - 67,824,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2067,660,680 - 67,809,086 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603349,732,881 - 49,896,207 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474229,398,544 - 29,485,165 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474229,397,811 - 29,525,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnajc6
850 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1071
Count of miRNA genes:339
Interacting mature miRNAs:481
Transcripts:ENSRNOT00000064077
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat

Markers in Region
D5Rhw2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,215,221 - 116,215,425 (+)MAPPERmRatBN7.2
Rnor_6.05120,424,289 - 120,424,492NCBIRnor6.0
Rnor_5.05124,304,325 - 124,304,528UniSTSRnor5.0
RGSC_v3.45122,241,372 - 122,241,575UniSTSRGSC3.4
Celera5114,745,148 - 114,745,351UniSTS
Cytogenetic Map5q33UniSTS
D5Rhw3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,259,680 - 116,259,847 (+)MAPPERmRatBN7.2
Rnor_6.05120,468,749 - 120,468,915NCBIRnor6.0
Rnor_5.05124,346,857 - 124,347,023UniSTSRnor5.0
RGSC_v3.45122,285,349 - 122,285,515UniSTSRGSC3.4
Celera5114,782,645 - 114,782,811UniSTS
Cytogenetic Map5q33UniSTS
D5Rhw1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,206,626 - 116,206,836 (+)MAPPERmRatBN7.2
Rnor_6.05120,415,696 - 120,415,905NCBIRnor6.0
Rnor_5.05124,295,732 - 124,295,941UniSTSRnor5.0
RGSC_v3.45122,232,779 - 122,232,988UniSTSRGSC3.4
Celera5114,736,545 - 114,736,764UniSTS
Cytogenetic Map5q33UniSTS
BF393615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,262,749 - 116,262,922 (+)MAPPERmRatBN7.2
Rnor_6.05120,471,817 - 120,471,989NCBIRnor6.0
Rnor_5.05124,349,925 - 124,350,097UniSTSRnor5.0
RGSC_v3.45122,288,417 - 122,288,589UniSTSRGSC3.4
Celera5114,785,713 - 114,785,885UniSTS
RH 3.4 Map5787.6UniSTS
Cytogenetic Map5q33UniSTS
BE102465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,281,103 - 116,281,263 (+)MAPPERmRatBN7.2
Rnor_6.05120,490,171 - 120,490,330NCBIRnor6.0
Rnor_5.05124,368,328 - 124,368,487UniSTSRnor5.0
RGSC_v3.45122,306,771 - 122,306,930UniSTSRGSC3.4
Celera5114,803,976 - 114,804,135UniSTS
RH 3.4 Map5788.3UniSTS
Cytogenetic Map5q33UniSTS
RH137225  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,155,236 - 116,155,430 (+)MAPPERmRatBN7.2
Rnor_6.05120,365,565 - 120,365,758NCBIRnor6.0
Rnor_5.05124,245,441 - 124,245,634UniSTSRnor5.0
RGSC_v3.45122,180,063 - 122,180,256UniSTSRGSC3.4
Celera5114,686,470 - 114,686,663UniSTS
RH 3.4 Map5788.3UniSTS
Cytogenetic Map5q33UniSTS
RH140626  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,281,778 - 116,281,986 (+)MAPPERmRatBN7.2
Rnor_6.05120,490,846 - 120,491,053NCBIRnor6.0
Rnor_5.05124,369,003 - 124,369,210UniSTSRnor5.0
RGSC_v3.45122,307,446 - 122,307,653UniSTSRGSC3.4
Celera5114,804,651 - 114,804,858UniSTS
RH 3.4 Map5788.9UniSTS
Cytogenetic Map5q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 32 113 72 71 40 25 40 6 179 77 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000086259   ⟹   ENSRNOP00000070493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5116,130,676 - 116,283,448 (+)Ensembl
Rnor_6.0 Ensembl5120,340,646 - 120,492,442 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086539   ⟹   ENSRNOP00000070257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5116,130,676 - 116,283,448 (+)Ensembl
Rnor_6.0 Ensembl5120,340,735 - 120,492,487 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110252   ⟹   ENSRNOP00000086865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5116,119,676 - 116,283,448 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113921   ⟹   ENSRNOP00000095523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5116,174,863 - 116,283,448 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116178   ⟹   ENSRNOP00000084012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5116,199,041 - 116,283,448 (+)Ensembl
RefSeq Acc Id: NM_001415921   ⟹   NP_001402850
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,290,199 - 121,398,775 (+)NCBI
mRatBN7.25116,174,871 - 116,283,448 (+)NCBI
RefSeq Acc Id: XM_006238447   ⟹   XP_006238509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,232,532 - 121,398,763 (+)NCBI
mRatBN7.25116,120,069 - 116,283,436 (+)NCBI
Rnor_6.05120,330,372 - 120,492,503 (+)NCBI
Rnor_5.05124,210,621 - 124,370,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238448   ⟹   XP_006238510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,243,274 - 121,398,763 (+)NCBI
mRatBN7.25116,130,379 - 116,283,436 (+)NCBI
Rnor_6.05120,339,874 - 120,492,503 (+)NCBI
Rnor_5.05124,210,621 - 124,370,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238449   ⟹   XP_006238511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,246,130 - 121,398,763 (+)NCBI
mRatBN7.25116,130,382 - 116,283,436 (+)NCBI
Rnor_6.05120,339,874 - 120,492,503 (+)NCBI
Rnor_5.05124,210,621 - 124,370,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109918   ⟹   XP_038965846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85121,235,652 - 121,398,763 (+)NCBI
mRatBN7.25116,120,328 - 116,283,436 (+)NCBI
RefSeq Acc Id: XP_006238509   ⟸   XM_006238447
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A6P4 (UniProtKB/TrEMBL),   A0A8I5ZWX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238510   ⟸   XM_006238448
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JY26 (UniProtKB/TrEMBL),   A6JRN8 (UniProtKB/TrEMBL),   D4A0I5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238511   ⟸   XM_006238449
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZWX0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070257   ⟸   ENSRNOT00000086539
Ensembl Acc Id: ENSRNOP00000070493   ⟸   ENSRNOT00000086259
RefSeq Acc Id: XP_038965846   ⟸   XM_039109918
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZWX0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095523   ⟸   ENSRNOT00000113921
Ensembl Acc Id: ENSRNOP00000084012   ⟸   ENSRNOT00000116178
Ensembl Acc Id: ENSRNOP00000086865   ⟸   ENSRNOT00000110252
RefSeq Acc Id: NP_001402850   ⟸   NM_001415921
- UniProtKB: A0A8I6AMT9 (UniProtKB/TrEMBL),   A0A8I5ZWX0 (UniProtKB/TrEMBL)
Protein Domains
C2 tensin-type   J   Phosphatase tensin-type   Tyrosine specific protein phosphatases

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JY26-F1-model_v2 AlphaFold A0A0G2JY26 1-938 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693859
Promoter ID:EPDNEW_R4384
Type:single initiation site
Name:Dnajc6_1
Description:DnaJ heat shock protein family member C6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05120,340,763 - 120,340,823EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309900 AgrOrtholog
BioCyc Gene G2FUF-40537 BioCyc
Ensembl Genes ENSRNOG00000052887 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086259.2 UniProtKB/TrEMBL
  ENSRNOT00000086539.2 UniProtKB/TrEMBL
  ENSRNOT00000110252.1 UniProtKB/TrEMBL
  ENSRNOT00000113921.1 UniProtKB/TrEMBL
  ENSRNOT00000116178.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/TrEMBL
  2.60.40.1110 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro C2_domain_sf UniProtKB/TrEMBL
  DnaJ_dom_sf UniProtKB/TrEMBL
  DnaJ_N UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tensin_lipid_phosphatase_dom UniProtKB/TrEMBL
  Tensin_phosphatase_C2-dom UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene 313409 ENTREZGENE
PANTHER AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE AUXILIN-RELATED UniProtKB/TrEMBL
Pfam PTEN_C2 UniProtKB/TrEMBL
PhenoGen Dnajc6 PhenoGen
PROSITE C2_TENSIN UniProtKB/TrEMBL
  DNAJ_2 UniProtKB/TrEMBL
  PPASE_TENSIN UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052887 RatGTEx
SMART DnaJ UniProtKB/TrEMBL
  PTEN_C2 UniProtKB/TrEMBL
Superfamily-SCOP DnaJ_N UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2JY26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWX0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMT9 ENTREZGENE, UniProtKB/TrEMBL
  A6JRN8 ENTREZGENE, UniProtKB/TrEMBL
  D4A0I5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnajc6  DnaJ heat shock protein family (Hsp40) member C6  Dnajc6  DnaJ (Hsp40) homolog, subfamily C, member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dnajc6  DnaJ (Hsp40) homolog, subfamily C, member 6   Dnajc6_predicted  DnaJ (Hsp40) homolog, subfamily C, member 6 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dnajc6_predicted  DnaJ (Hsp40) homolog, subfamily C, member 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED