Cabcoco1 (ciliary associated calcium binding coiled-coil 1) - Rat Genome Database

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Gene: Cabcoco1 (ciliary associated calcium binding coiled-coil 1) Rattus norvegicus
Analyze
Symbol: Cabcoco1
Name: ciliary associated calcium binding coiled-coil 1
RGD ID: 1306739
Description: Predicted to enable calcium ion binding activity. Predicted to be located in centrosome; cytoplasm; and sperm flagellum. Orthologous to human CABCOCO1 (ciliary associated calcium binding coiled-coil 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ciliary-associated calcium-binding coiled-coil protein 1; hypothetical protein LOC361834; LOC361834; RGD1306739; similar to RIKEN cDNA 1700040L02; uncharacterized protein C10orf107 homolog; uncharacterized protein LOC361834
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82020,057,462 - 20,166,732 (+)NCBIGRCr8
mRatBN7.22020,058,492 - 20,167,973 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2020,058,454 - 20,167,725 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2020,787,469 - 20,896,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02020,139,929 - 20,249,119 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02020,615,167 - 20,724,352 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02021,316,770 - 21,426,036 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2021,316,826 - 21,426,034 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02023,418,513 - 23,526,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42020,871,970 - 20,981,865 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12020,885,786 - 20,995,667 (+)NCBI
Celera2021,424,970 - 21,532,751 (+)NCBICelera
Cytogenetic Map20p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:26990073  


Genomics

Comparative Map Data
Cabcoco1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82020,057,462 - 20,166,732 (+)NCBIGRCr8
mRatBN7.22020,058,492 - 20,167,973 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2020,058,454 - 20,167,725 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2020,787,469 - 20,896,660 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02020,139,929 - 20,249,119 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02020,615,167 - 20,724,352 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02021,316,770 - 21,426,036 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2021,316,826 - 21,426,034 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02023,418,513 - 23,526,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42020,871,970 - 20,981,865 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12020,885,786 - 20,995,667 (+)NCBI
Celera2021,424,970 - 21,532,751 (+)NCBICelera
Cytogenetic Map20p11NCBI
CABCOCO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381061,662,929 - 61,766,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1061,662,929 - 61,766,766 (+)EnsemblGRCh38hg38GRCh38
GRCh371063,422,687 - 63,526,524 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361063,092,725 - 63,196,107 (+)NCBINCBI36Build 36hg18NCBI36
Build 341063,092,724 - 63,196,097NCBI
Celera1056,689,752 - 56,792,965 (+)NCBICelera
Cytogenetic Map10q21.2NCBI
HuRef1057,411,681 - 57,515,315 (+)NCBIHuRef
CHM1_11063,704,905 - 63,808,265 (+)NCBICHM1_1
T2T-CHM13v2.01062,519,703 - 62,623,652 (+)NCBIT2T-CHM13v2.0
Cabcoco1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391068,266,786 - 68,377,751 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1068,266,783 - 68,377,726 (-)EnsemblGRCm39 Ensembl
GRCm381068,430,956 - 68,541,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1068,430,953 - 68,541,896 (-)EnsemblGRCm38mm10GRCm38
MGSCv371067,893,704 - 68,004,623 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361067,826,313 - 67,937,232 (-)NCBIMGSCv36mm8
Celera1069,527,662 - 69,638,253 (-)NCBICelera
Cytogenetic Map10B5.2NCBI
cM Map1035.4NCBI
Cabcoco1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542515,007,643 - 15,115,648 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542515,007,833 - 15,115,084 (+)NCBIChiLan1.0ChiLan1.0
CABCOCO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2873,865,952 - 73,969,690 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11073,871,239 - 73,975,012 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01058,187,953 - 58,291,787 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11060,518,657 - 60,621,981 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1060,518,684 - 60,621,981 (+)Ensemblpanpan1.1panPan2
CABCOCO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1413,687,468 - 13,804,773 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl413,687,218 - 13,803,095 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha413,893,183 - 14,010,513 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0413,951,106 - 14,068,634 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl413,951,084 - 14,067,291 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1413,939,987 - 14,057,308 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0414,055,116 - 14,176,890 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0414,420,291 - 14,537,613 (+)NCBIUU_Cfam_GSD_1.0
Cabcoco1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721367,286,518 - 67,390,083 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366141,372,788 - 1,476,508 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366141,373,873 - 1,476,470 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CABCOCO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1465,152,923 - 65,277,972 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11465,152,913 - 65,277,978 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21470,161,171 - 70,286,614 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CABCOCO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1969,514,710 - 69,619,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl969,514,616 - 69,618,981 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604830,399,889 - 30,504,728 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cabcoco1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247911,943,788 - 2,058,630 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247911,945,194 - 2,058,039 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cabcoco1
337 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:99
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000000785
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat

Markers in Region
RH132894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22020,157,492 - 20,157,703 (+)MAPPERmRatBN7.2
Rnor_6.02021,415,805 - 21,416,015NCBIRnor6.0
Rnor_5.02023,516,563 - 23,516,773UniSTSRnor5.0
RGSC_v3.42020,971,634 - 20,971,844UniSTSRGSC3.4
Celera2021,522,520 - 21,522,730UniSTS
Cytogenetic Map20p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000000785   ⟹   ENSRNOP00000000785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2020,058,454 - 20,167,725 (+)Ensembl
Rnor_6.0 Ensembl2021,316,826 - 21,426,034 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098928   ⟹   ENSRNOP00000095689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2020,059,116 - 20,167,725 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103305   ⟹   ENSRNOP00000077935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2020,062,013 - 20,167,725 (+)Ensembl
RefSeq Acc Id: NM_001134576   ⟹   NP_001128048
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82020,057,544 - 20,166,730 (+)NCBI
mRatBN7.22020,058,533 - 20,167,725 (+)NCBI
Rnor_6.02021,316,826 - 21,426,034 (+)NCBI
Rnor_5.02023,418,513 - 23,526,794 (+)NCBI
RGSC_v3.42020,871,970 - 20,981,865 (+)RGD
Celera2021,424,970 - 21,532,751 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256355   ⟹   XP_006256417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82020,057,462 - 20,166,732 (+)NCBI
mRatBN7.22020,058,492 - 20,167,973 (+)NCBI
Rnor_6.02021,316,777 - 21,426,036 (+)NCBI
Rnor_5.02023,418,513 - 23,526,794 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006256356   ⟹   XP_006256418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82020,058,142 - 20,166,732 (+)NCBI
mRatBN7.22020,059,267 - 20,167,973 (+)NCBI
Rnor_6.02021,317,551 - 21,426,036 (+)NCBI
Rnor_5.02023,418,513 - 23,526,794 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098858   ⟹   XP_038954786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82020,058,191 - 20,166,732 (+)NCBI
mRatBN7.22020,059,367 - 20,167,973 (+)NCBI
RefSeq Acc Id: NP_001128048   ⟸   NM_001134576
- UniProtKB: A6JKU4 (UniProtKB/TrEMBL),   A0A8I5Y6I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256417   ⟸   XM_006256355
- Peptide Label: isoform X1
- UniProtKB: D3ZD36 (UniProtKB/TrEMBL),   A0A8I5Y6I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256418   ⟸   XM_006256356
- Peptide Label: isoform X2
- UniProtKB: A0A8I6APL6 (UniProtKB/TrEMBL),   A0A8I5Y6I4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000785   ⟸   ENSRNOT00000000785
RefSeq Acc Id: XP_038954786   ⟸   XM_039098858
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y6I4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077935   ⟸   ENSRNOT00000103305
Ensembl Acc Id: ENSRNOP00000095689   ⟸   ENSRNOT00000098928

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZD36-F1-model_v2 AlphaFold D3ZD36 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701558
Promoter ID:EPDNEW_R12082
Type:initiation region
Name:Cabcoco1_1
Description:ciliary associated calcium binding coiled-coil 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02021,316,836 - 21,316,896EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306739 AgrOrtholog
BioCyc Gene G2FUF-3917 BioCyc
Ensembl Genes ENSRNOG00000000634 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000785.6 UniProtKB/TrEMBL
  ENSRNOT00000098928.1 UniProtKB/TrEMBL
  ENSRNOT00000103305.1 UniProtKB/TrEMBL
InterPro CLAMP UniProtKB/TrEMBL
KEGG Report rno:361834 UniProtKB/TrEMBL
NCBI Gene 361834 ENTREZGENE
PANTHER CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1 UniProtKB/TrEMBL
  PTHR28457 UniProtKB/TrEMBL
Pfam CLAMP UniProtKB/TrEMBL
PhenoGen Cabcoco1 PhenoGen
RatGTEx ENSRNOG00000000634 RatGTEx
UniProt A0A8I5Y6I4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APL6 ENTREZGENE, UniProtKB/TrEMBL
  A6JKU4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZD36 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-23 Cabcoco1  ciliary associated calcium binding coiled-coil 1  RGD1306739  similar to RIKEN cDNA 1700040L02  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1306739  similar to RIKEN cDNA 1700040L02   RGD1306739_predicted  similar to RIKEN cDNA 1700040L02 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1306739_predicted  similar to RIKEN cDNA 1700040L02 (predicted)  LOC361834_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361834_predicted  similar to RIKEN cDNA 1700040L02 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL