Aldh1a1 (aldehyde dehydrogenase 1 family member A1) - Rat Genome Database

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Gene: Aldh1a1 (aldehyde dehydrogenase 1 family member A1) Ictidomys tridecemlineatus
Analyze
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family member A1
RGD ID: 12578952
Description: ENCODES a protein that exhibits 3-chloroallyl aldehyde dehydrogenase activity (ortholog); aldehyde dehydrogenase (NAD+) activity (ortholog); aminobutyraldehyde dehydrogenase (NAD+) activity (ortholog); INVOLVED IN 9-cis-retinoic acid biosynthetic process (ortholog); 9-cis-retinoic acid metabolic process (ortholog); apoptotic process (ortholog); PARTICIPATES IN cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; ifosfamide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Creutzfeldt-Jakob disease (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN axon (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: retinal dehydrogenase 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947132,159,211 - 132,303,931 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365038,868,961 - 8,918,532 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365038,869,073 - 8,953,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)
cytoplasm  (IEA)
cytosol  (IEA)
synapse  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Aldh1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947132,159,211 - 132,303,931 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365038,868,961 - 8,918,532 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365038,869,073 - 8,953,726 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38972,900,671 - 72,953,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl972,900,671 - 73,080,442 (-)EnsemblGRCh38hg38GRCh38
GRCh37975,515,587 - 75,567,969 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36974,705,407 - 74,757,789 (-)NCBINCBI36Build 36hg18NCBI36
Build 34972,745,141 - 72,797,523NCBI
Celera946,088,447 - 46,140,830 (-)NCBICelera
Cytogenetic Map9q21.13NCBI
HuRef945,338,144 - 45,390,773 (-)NCBIHuRef
CHM1_1975,662,616 - 75,715,255 (-)NCBICHM1_1
T2T-CHM13v2.0985,051,589 - 85,103,957 (-)NCBIT2T-CHM13v2.0
Aldh1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391920,469,947 - 20,620,827 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1920,470,079 - 20,620,829 (+)EnsemblGRCm39 Ensembl
GRCm381920,492,583 - 20,643,463 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1920,492,715 - 20,643,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371920,676,472 - 20,717,952 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361920,669,079 - 20,710,559 (+)NCBIMGSCv36mm8
Celera1921,323,202 - 21,366,435 (+)NCBICelera
Cytogenetic Map19BNCBI
cM Map1913.91NCBI
Aldh1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,426,939 - 227,579,497 (+)NCBIGRCr8
mRatBN7.21218,000,470 - 218,152,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,042,127 - 218,152,961 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1226,448,507 - 226,490,531 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01233,385,074 - 233,427,098 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01226,203,095 - 226,245,121 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,222,689 - 238,264,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,222,521 - 238,264,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01245,340,587 - 245,562,970 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,731,675 - 223,773,285 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11223,895,697 - 223,937,307 (+)NCBI
Celera1215,379,207 - 215,421,068 (+)NCBICelera
Cytogenetic Map1q51NCBI
ALDH1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21172,085,972 - 72,265,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1972,091,914 - 72,271,273 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0951,737,305 - 51,916,648 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1971,680,352 - 71,859,144 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl971,680,890 - 71,814,085 (-)Ensemblpanpan1.1panPan2
ALDH1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1184,940,411 - 84,994,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl184,940,411 - 84,994,789 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha185,406,217 - 85,460,597 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0185,390,369 - 85,444,756 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl185,390,360 - 85,444,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1185,159,477 - 85,213,817 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0184,862,384 - 84,917,606 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0185,621,439 - 85,676,732 (+)NCBIUU_Cfam_GSD_1.0
ALDH1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,161,299 - 226,217,308 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,163,347 - 226,217,342 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21252,778,605 - 252,808,516 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11283,949,529 - 84,092,452 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1283,949,399 - 84,009,003 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603872,378,038 - 72,569,020 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh1a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624811505,101 - 563,855 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624811505,297 - 563,795 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000003291   ⟹   ENSSTOP00000002943
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365038,868,961 - 8,918,532 (-)Ensembl
RefSeq Acc Id: XM_021725627   ⟹   XP_021581302
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947132,215,802 - 132,303,931 (+)NCBI
SpeTri2.0NW_0049365038,869,073 - 8,953,726 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040285665   ⟹   XP_040141599
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947132,159,212 - 132,303,931 (+)NCBI
RefSeq Acc Id: XM_040285666   ⟹   XP_040141600
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947132,159,212 - 132,303,931 (+)NCBI
RefSeq Acc Id: XM_040285667   ⟹   XP_040141601
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947132,215,802 - 132,303,931 (+)NCBI
RefSeq Acc Id: XM_040285668   ⟹   XP_040141602
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947132,159,211 - 132,303,931 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021581302 (Get FASTA)   NCBI Sequence Viewer  
  XP_040141599 (Get FASTA)   NCBI Sequence Viewer  
  XP_040141600 (Get FASTA)   NCBI Sequence Viewer  
  XP_040141601 (Get FASTA)   NCBI Sequence Viewer  
  XP_040141602 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002943.2
GenBank Protein KAG3287107 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021581302   ⟸   XM_021725627
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040141602   ⟸   XM_040285668
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040141599   ⟸   XM_040285665
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040141600   ⟸   XM_040285666
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040141601   ⟸   XM_040285667
- Peptide Label: isoform X3
Ensembl Acc Id: ENSSTOP00000002943   ⟸   ENSSTOT00000003291
Protein Domains
Aldehyde dehydrogenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003287 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003291.3 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/TrEMBL
NCBI Gene Aldh1a1 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/TrEMBL
  RETINAL DEHYDROGENASE 1 UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/TrEMBL
UniProt I3M206_ICTTR UniProtKB/TrEMBL