Pgr (progesterone receptor) - Rat Genome Database

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Gene: Pgr (progesterone receptor) Ictidomys tridecemlineatus
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Symbol: Pgr
Name: progesterone receptor
RGD ID: 12472043
Description: ENCODES a protein that exhibits hormone binding (ortholog); nuclear steroid receptor activity (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); cellular response to follicle-stimulating hormone stimulus (ortholog); cellular response to gonadotropin stimulus (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Mammary Neoplasms (ortholog); ataxia telangiectasia (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); chromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494784,948,508 - 85,038,416 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365516,498,553 - 6,573,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365516,498,553 - 6,573,212 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to estrogen stimulus  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
cellular response to gonadotropin stimulus  (ISO)
cellular response to luteinizing hormone stimulus  (ISO)
cellular response to wortmannin  (ISO)
diterpenoid metabolic process  (ISO)
epithelial cell maturation  (IEA,ISO)
estrous cycle  (ISO)
female mating behavior  (ISO)
glandular epithelial cell maturation  (IEA,ISO)
lung alveolus development  (IEA,ISO)
luteinization  (ISO)
maintenance of protein location in nucleus  (IEA)
mammary gland development  (IEA,ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of gene expression  (IEA)
negative regulation of granulosa cell apoptotic process  (ISO)
ovulation from ovarian follicle  (IEA,ISO)
paracrine signaling  (IEA,ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA)
progesterone receptor signaling pathway  (IEA,ISO)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of epithelial cell proliferation  (IEA,ISO)
response to cocaine  (ISO)
response to estrogen  (ISO)
response to progesterone  (ISO)
smooth muscle relaxation of the bladder outlet  (ISO)
steroid hormone receptor signaling pathway  (IEA)
tertiary branching involved in mammary gland duct morphogenesis  (IEA,ISO)

Cellular Component
axon  (ISO)
axon terminus  (ISO)
chromatin  (IEA,ISO)
cytoplasm  (IEA)
dendrite  (ISO)
dendritic spine  (ISO)
nucleus  (IEA)
perikaryon  (ISO)
plasma membrane  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Pgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494784,948,508 - 85,038,416 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365516,498,553 - 6,573,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365516,498,553 - 6,573,212 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811101,029,624 - 101,129,813 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11101,029,624 - 101,129,813 (-)EnsemblGRCh38hg38GRCh38
GRCh3711100,900,355 - 101,000,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611100,414,313 - 100,506,465 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411100,414,312 - 100,506,465NCBI
Celera1198,069,715 - 98,169,894 (-)NCBICelera
Cytogenetic Map11q22.1NCBI
HuRef1196,837,449 - 96,937,628 (-)NCBIHuRef
CHM1_111100,783,609 - 100,883,736 (-)NCBICHM1_1
T2T-CHM13v2.011101,039,187 - 101,139,328 (-)NCBIT2T-CHM13v2.0
Pgr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3998,890,017 - 8,968,612 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl98,899,834 - 8,968,612 (+)EnsemblGRCm39 Ensembl
GRCm3898,898,900 - 8,968,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl98,899,833 - 8,968,611 (+)EnsemblGRCm38mm10GRCm38
MGSCv3798,899,833 - 8,968,611 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3698,862,303 - 8,926,995 (+)NCBIMGSCv36mm8
Celera96,279,529 - 6,348,253 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Pgr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8814,354,398 - 14,413,271 (+)NCBIGRCr8
mRatBN7.286,072,673 - 6,131,552 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl86,072,673 - 6,131,344 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx810,003,167 - 10,062,099 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.088,300,792 - 8,359,726 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.086,329,892 - 6,388,768 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.087,128,656 - 7,187,796 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl87,128,656 - 7,187,796 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.087,113,895 - 7,172,761 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.485,784,717 - 5,845,901 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.185,784,716 - 5,845,901 (+)NCBI
Celera87,609,728 - 7,668,047 (+)NCBICelera
Cytogenetic Map8q11NCBI
Pgr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554124,643,839 - 4,693,478 (-)NCBIChiLan1.0ChiLan1.0
PGR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29101,848,679 - 101,939,634 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111102,925,904 - 103,028,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01195,997,677 - 96,098,866 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11199,508,571 - 99,598,020 (-)NCBIpanpan1.1PanPan1.1panPan2
PGR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.121447,197 - 552,511 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl21447,319 - 552,511 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha21461,376 - 566,187 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.021609,104 - 717,242 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl21609,104 - 742,638 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.121392,996 - 497,928 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.021478,480 - 583,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.021532,736 - 637,643 (+)NCBIUU_Cfam_GSD_1.0
PGR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl932,035,684 - 32,129,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1932,035,684 - 32,129,776 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2936,044,789 - 36,138,540 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9p13-p11NCBI
PGR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,420,970 - 92,519,128 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl192,430,453 - 92,517,296 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604333,353,079 - 33,447,583 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248781,714,559 - 1,762,421 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248781,714,196 - 1,769,302 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005329107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000023650   ⟹   ENSSTOP00000019036
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365516,498,553 - 6,573,222 (+)Ensembl
RefSeq Acc Id: XM_005329107   ⟹   XP_005329164
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494784,948,508 - 85,038,416 (-)NCBI
SpeTri2.0NW_0049365516,498,553 - 6,573,212 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329164 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019036.2
GenBank Protein KAG3286412 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005329164   ⟸   XM_005329107
- UniProtKB: I3N3U0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000019036   ⟸   ENSSTOT00000023650
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020694 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023650.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR3 UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  Progest_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
NCBI Gene Pgr ENTREZGENE
PANTHER KNIRPS-RELATED PROTEIN-RELATED UniProtKB/TrEMBL
  PROGESTERONE RECEPTOR UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  Prog_receptor UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS PROGESTRONER UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt I3N3U0 ENTREZGENE, UniProtKB/TrEMBL