Cripto (cripto, EGF-CFC family member) - Rat Genome Database

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Gene: Cripto (cripto, EGF-CFC family member) Ictidomys tridecemlineatus
Analyze
Symbol: Cripto
Name: cripto, EGF-CFC family member
RGD ID: 12457587
Description: ENCODES a protein that exhibits coreceptor activity (ortholog); growth factor activity (ortholog); nodal binding (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); anterior/posterior axis specification, embryo (ortholog); cardiac muscle cell differentiation (ortholog); PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH colon cancer (ortholog); congenital heart disease (ortholog); Forebrain Defects (ortholog); FOUND IN apical plasma membrane (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tdgf1; teratocarcinoma-derived growth factor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,900,937 - 200,905,070 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936596451,483 - 453,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CriptoSquirrelForebrain Defects  ISOCRIPTO (Homo sapiens)8554872ClinVar Annotator: match by term: Forebrain defectsClinVarPMID:11062482 and PMID:12073012
CriptoSquirrelProgressive Microcephaly with Seizures and Cerebral and Cerebellar Atrophy  ISOCRIPTO (Homo sapiens)8554872ClinVar Annotator: match by term: Microcephaly more ...ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CriptoSquirrelholoprosencephaly  ISOCRIPTO (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:12073012
CriptoSquirrelvisceral heterotaxy  ISOCRIPTO (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:11062482


Biological Process
1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CriptoSquirrelanterior/posterior axis specification acts_upstream_of_or_withinISOMGI:12014149068941 PMID:18241853MGIPMID:18241853
CriptoSquirrelanterior/posterior axis specification, embryo acts_upstream_of_or_withinISOMGI:19342069068941 PMID:9790191MGIPMID:9790191
CriptoSquirrelcardiac muscle cell differentiation acts_upstream_of_or_withinISOMGI:18575189068941 PMID:9876177MGIPMID:9876177
CriptoSquirrelcell migration involved in sprouting angiogenesis involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to epidermal growth factor stimulus involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to fibroblast growth factor stimulus involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to hepatocyte growth factor stimulus involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to interleukin-6 involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to tumor necrosis factor involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelcellular response to type II interferon involved_inISOCRIPTO (Homo sapiens)9068941 PMID:17720976UniProtPMID:17720976
CriptoSquirrelepidermal growth factor receptor signaling pathway NOT|acts_upstream_of_or_withinISOCRIPTO (Homo sapiens)9068941 PMID:8006041MGIPMID:8006041
CriptoSquirrelfibroblast proliferation acts_upstream_ofISOMGI:18575189068941 PMID:9876177MGIPMID:9876177
CriptoSquirrelgastrulation acts_upstream_of_or_withinISOMGI:12014149068941 PMID:18241853MGIPMID:18241853
CriptoSquirrelheart development involved_inISOCRIPTO (Homo sapiens)9068941 PMID:9576836UniProtPMID:9576836
CriptoSquirrelheart development involved_inISOCripto (Mus musculus)9068941 PMID:9576836UniProtPMID:9576836
CriptoSquirrelin utero embryonic development acts_upstream_of_or_withinISOMGI:18575189068941 PMID:9876177MGIPMID:9876177
CriptoSquirrelmorphogenesis of a branching structure involved_inISOCripto (Mus musculus)9068941 PMID:11133982UniProtPMID:11133982
CriptoSquirrelnegative regulation of apoptotic process involved_inISOCRIPTO (Homo sapiens)9068941 PMID:10493495UniProtPMID:10493495
CriptoSquirrelnegative regulation of transforming growth factor beta receptor signaling pathway acts_upstream_of_or_withinISOMGI:958359068941 PMID:17991893MGIPMID:17991893
CriptoSquirrelnodal signaling pathway involved_inISOUniProtKB:P430219068941 PMID:11389842UniProtPMID:11389842
1 to 20 of 34 rows

Cellular Component
1 to 12 of 12 rows

  
1 to 12 of 12 rows

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
CriptoSquirrelglypican signaling pathway  ISOCRIPTO (Homo sapiens)9068941 PIDPID:200026


Cripto
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,900,937 - 200,905,070 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936596451,483 - 453,892 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRIPTO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,574,535 - 46,582,457 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,574,534 - 46,582,457 (+)EnsemblGRCh38hg38GRCh38
GRCh37346,616,025 - 46,623,947 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,594,217 - 46,598,957 (+)NCBINCBI36Build 36hg18NCBI36
Build 34346,594,216 - 46,598,954NCBI
Celera346,553,783 - 46,561,683 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,658,557 - 46,666,459 (+)NCBIHuRef
CHM1_1346,566,173 - 46,574,073 (+)NCBICHM1_1
T2T-CHM13v2.0346,590,623 - 46,598,545 (+)NCBIT2T-CHM13v2.0
Cripto
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,768,676 - 110,775,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,768,671 - 110,775,226 (-)EnsemblGRCm39 Ensembl
GRCm389110,939,608 - 110,946,158 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,939,603 - 110,946,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv379110,842,112 - 110,848,662 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,784,418 - 110,790,883 (-)NCBIMGSCv36mm8
Celera9110,664,719 - 110,671,594 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
Cripto
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,803,182 - 119,808,714 (-)NCBIGRCr8
mRatBN7.28110,924,774 - 110,938,545 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,925,024 - 110,930,308 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.08119,215,266 - 119,220,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,215,495 - 119,219,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,554,829 - 118,560,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,341,587 - 115,346,871 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8110,206,645 - 110,212,260 (-)NCBICelera
Cytogenetic Map8q32NCBI
Cripto
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542025,477,122 - 25,479,969 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542025,476,975 - 25,479,969 (-)NCBIChiLan1.0ChiLan1.0
CRIPTO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,530,938 - 46,535,958 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,535,714 - 46,540,728 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,473,282 - 46,478,454 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,577,949 - 47,583,126 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,577,949 - 47,583,126 (+)Ensemblpanpan1.1panPan2
CRIPTO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,137,939 - 42,140,590 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,053,910 - 42,056,560 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,620,327 - 42,622,979 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,620,327 - 42,623,866 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,861,683 - 41,864,330 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,262,807 - 42,265,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,543,717 - 42,546,368 (-)NCBIUU_Cfam_GSD_1.0
CRIPTO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,540,314 - 29,543,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,537,874 - 29,544,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,774,947 - 32,777,177 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CRIPTO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,993,724 - 8,000,935 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,997,383 - 8,000,629 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,149,573 - 159,153,094 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cripto
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473074,547,226 - 74,550,526 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.
RefSeq Transcripts XM_005333069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_005333069   ⟹   XP_005333126
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118200,900,937 - 200,905,070 (+)NCBI
SpeTri2.0NW_004936596451,483 - 453,892 (+)NCBI
Sequence:
Protein RefSeqs XP_005333126 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3279783 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005333126   ⟸   XM_005333069
- Sequence:



Database
Acc Id
Source(s)
NCBI Gene Tdgf1 ENTREZGENE


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-13 Cripto  cripto, EGF-CFC family member  Tdgf1  teratocarcinoma-derived growth factor 1  Symbol and/or name change 5135510 APPROVED