RDH12 (retinol dehydrogenase 12) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: RDH12 (retinol dehydrogenase 12) Canis lupus familiaris
Analyze
Symbol: RDH12
Name: retinol dehydrogenase 12
RGD ID: 12358280
Description: ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); all-trans-retinol dehydrogenase (NADP+) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN cellular detoxification of aldehyde (inferred); retinol metabolic process (inferred); visual perception (inferred); PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoid cycle metabolic pathway; ASSOCIATED WITH cone-rod dystrophy (ortholog); Eye Abnormalities (ortholog); fundus dystrophy (ortholog); FOUND IN photoreceptor inner segment (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,685,045 - 41,696,120 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,684,996 - 41,695,447 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,376,188 - 41,387,256 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0841,915,013 - 41,926,089 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl841,915,087 - 41,926,101 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,530,993 - 41,542,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,604,398 - 41,615,461 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0841,963,799 - 41,974,867 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
RDH12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,685,045 - 41,696,120 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,684,996 - 41,695,447 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,376,188 - 41,387,256 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0841,915,013 - 41,926,089 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl841,915,087 - 41,926,101 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,530,993 - 41,542,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,604,398 - 41,615,461 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0841,963,799 - 41,974,867 (+)NCBIUU_Cfam_GSD_1.0
RDH12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,701,886 - 67,734,451 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,701,886 - 67,734,451 (+)EnsemblGRCh38hg38GRCh38
GRCh371468,168,603 - 68,201,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,258,943 - 67,270,921 (+)NCBINCBI36Build 36hg18NCBI36
Build 341467,258,942 - 67,270,920NCBI
Celera1448,227,645 - 48,260,203 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,338,282 - 48,370,752 (+)NCBIHuRef
CHM1_11468,107,353 - 68,139,905 (+)NCBICHM1_1
T2T-CHM13v2.01461,909,008 - 61,941,569 (+)NCBIT2T-CHM13v2.0
Rdh12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,255,687 - 79,269,438 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,255,688 - 79,269,439 (+)EnsemblGRCm39 Ensembl
GRCm381279,208,913 - 79,222,664 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,208,914 - 79,222,665 (+)EnsemblGRCm38mm10GRCm38
MGSCv371280,309,901 - 80,323,648 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361280,127,754 - 80,141,501 (+)NCBIMGSCv36mm8
Celera1280,673,293 - 80,687,040 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Rdh12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,748,457 - 103,761,379 (+)NCBIGRCr8
mRatBN7.2698,015,465 - 98,028,388 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,015,465 - 98,028,388 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,444,920 - 98,457,864 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,744,060 - 98,757,001 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,130,385 - 98,143,366 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,392,828 - 102,405,750 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,392,828 - 102,405,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,079,502 - 115,092,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46101,982,815 - 101,995,737 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16101,978,778 - 101,998,720 (+)NCBI
Celera696,400,484 - 96,413,406 (+)NCBICelera
Cytogenetic Map6q24NCBI
Rdh12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,473,096 - 2,487,623 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554662,473,145 - 2,485,779 (-)NCBIChiLan1.0ChiLan1.0
RDH12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,832,854 - 68,844,898 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11468,049,366 - 68,061,408 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,297,854 - 48,314,502 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11467,180,696 - 67,192,345 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1467,180,696 - 67,192,345 (+)Ensemblpanpan1.1panPan2
Rdh12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864063,069,723 - 63,080,452 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649511,111,105 - 11,121,341 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649511,111,247 - 11,121,976 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RDH12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,481,272 - 91,493,809 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1791,481,238 - 91,493,838 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,788,539 - 97,802,631 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RDH12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12444,957,854 - 44,971,855 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2444,959,921 - 44,971,836 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605333,183,713 - 33,200,221 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rdh12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473433,254,432 - 33,266,140 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473433,256,469 - 33,266,085 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RDH12
72 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 19 11 9 1 6 1 6 17 11 11 13 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005623559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038483562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038483563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038483564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038545031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038545032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038545033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038589688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038609141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038609142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038609143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_547866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000026064   ⟹   ENSCAFP00000024199
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl841,684,996 - 41,695,447 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845006357   ⟹   ENSCAFP00845005051
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl841,915,087 - 41,926,101 (+)Ensembl
RefSeq Acc Id: XM_005623559   ⟹   XP_005623616
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1841,685,045 - 41,696,120 (+)NCBI
Dog10K_Boxer_Tasha841,376,188 - 41,387,256 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038483562   ⟹   XP_038339490
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1841,530,993 - 41,542,054 (+)NCBI
RefSeq Acc Id: XM_038483563   ⟹   XP_038339491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1841,530,993 - 41,542,054 (+)NCBI
RefSeq Acc Id: XM_038483564   ⟹   XP_038339492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1841,530,993 - 41,542,054 (+)NCBI
RefSeq Acc Id: XM_038545031   ⟹   XP_038400959
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0841,963,799 - 41,974,867 (+)NCBI
RefSeq Acc Id: XM_038545032   ⟹   XP_038400960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0841,963,799 - 41,974,867 (+)NCBI
RefSeq Acc Id: XM_038545033   ⟹   XP_038400961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0841,963,799 - 41,974,867 (+)NCBI
RefSeq Acc Id: XM_038589688   ⟹   XP_038445616
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha841,376,188 - 41,387,256 (+)NCBI
RefSeq Acc Id: XM_038609141   ⟹   XP_038465069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0841,604,398 - 41,615,461 (+)NCBI
RefSeq Acc Id: XM_038609142   ⟹   XP_038465070
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0841,604,398 - 41,615,461 (+)NCBI
RefSeq Acc Id: XM_038609143   ⟹   XP_038465071
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0841,604,398 - 41,615,461 (+)NCBI
RefSeq Acc Id: XM_038673952   ⟹   XP_038529880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0841,915,013 - 41,926,089 (+)NCBI
RefSeq Acc Id: XM_038673954   ⟹   XP_038529882
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0841,915,013 - 41,926,089 (+)NCBI
RefSeq Acc Id: XM_038673955   ⟹   XP_038529883
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0841,915,013 - 41,926,089 (+)NCBI
RefSeq Acc Id: XM_547866   ⟹   XP_547866
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1841,685,045 - 41,696,120 (+)NCBI
Dog10K_Boxer_Tasha841,376,188 - 41,387,256 (+)NCBI
Sequence:
RefSeq Acc Id: XP_547866   ⟸   XM_547866
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SDK6 (UniProtKB/TrEMBL),   A0A8I3MRK7 (UniProtKB/TrEMBL),   A0A8C0QWD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005623616   ⟸   XM_005623559
- Peptide Label: isoform X2
- UniProtKB: A0A8C0QWD9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000024199   ⟸   ENSCAFT00000026064
RefSeq Acc Id: XP_038339490   ⟸   XM_038483562
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038339492   ⟸   XM_038483564
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038339491   ⟸   XM_038483563
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038465069   ⟸   XM_038609141
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038465071   ⟸   XM_038609143
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038465070   ⟸   XM_038609142
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038529880   ⟸   XM_038673952
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SDK6 (UniProtKB/TrEMBL),   A0A8I3MRK7 (UniProtKB/TrEMBL),   A0A8C0QWD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038529883   ⟸   XM_038673955
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038529882   ⟸   XM_038673954
- Peptide Label: isoform X2
- UniProtKB: A0A8C0QWD9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038445616   ⟸   XM_038589688
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038400959   ⟸   XM_038545031
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QWD9 (UniProtKB/TrEMBL),   A0A8C0SDK6 (UniProtKB/TrEMBL),   A0A8I3MRK7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038400961   ⟸   XM_038545033
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038400960   ⟸   XM_038545032
- Peptide Label: isoform X2
- UniProtKB: A0A8C0QWD9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845005051   ⟸   ENSCAFT00845006357


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016446 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016191 UniProtKB/TrEMBL
  ENSCAFG00040012017 UniProtKB/TrEMBL
  ENSCAFG00845003571 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026064.5 UniProtKB/TrEMBL
  ENSCAFT00030029761.1 UniProtKB/TrEMBL
  ENSCAFT00040022161.1 UniProtKB/TrEMBL
  ENSCAFT00845006357 ENTREZGENE
  ENSCAFT00845006357.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene RDH12 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED UniProtKB/TrEMBL
  RETINOL DEHYDROGENASE 12 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C0QWD9 ENTREZGENE
  A0A8C0SDK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MRK7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:52598 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-13 RDH12  retinol dehydrogenase 12    retinol dehydrogenase 12 (all-trans/9-cis/11-cis)  Symbol and/or name change 5135510 APPROVED