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Gene: APOC2 (apolipoprotein C2) Canis lupus familiaris

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Symbol:

APOC2

Name:

apolipoprotein C2

RGD ID:

12254569

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); molecular function activator activity (ortholog); INVOLVED IN lipoprotein transport (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Coronary Disease (ortholog); diabetes mellitus (ortholog); FOUND IN chylomicron (inferred); extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Apo-CII; ApoC-II; APOCII; apolipoprotein C-II

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	APOC2 (apolipoprotein C2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, Panther, Treefam
Mus musculus (house mouse):	Apoc2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Apoc2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Apoc2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	APOC2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Apoc2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	APOC2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	APOC2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Apoc2 (apolipoprotein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	110,504,806 - 110,506,986 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	110,504,815 - 110,506,961 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	109,985,886 - 109,987,967 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	111,034,576 - 111,036,727 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	111,034,585 - 111,036,734 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	110,709,344 - 110,711,427 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	110,344,763 - 110,346,846 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	111,213,632 - 111,215,715 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	Coronary Disease	susceptibility	ISO	RGD:1352001	9068941		RGD	PMID:7590197\|REF_RGD_ID:1601205
APOC2	Dog	diabetes mellitus		ISO	RGD:1352001	9068941	protein:increased expression:serum	RGD	PMID:2352345\|REF_RGD_ID:2313973
APOC2	Dog	end stage renal disease		ISO	RGD:1352001	9068941	associated with Diabetes Mellitus, Insulin-Dependent	RGD	PMID:8139482\|REF_RGD_ID:2313968
APOC2	Dog	familial hyperlipidemia	susceptibility	ISO	RGD:1352001	9068941		RGD	PMID:1782747\|REF_RGD_ID:1599175
APOC2	Dog	hepatocellular carcinoma		ISO	RGD:1352001	9068941	associated with hepatitis B; mRNA:increased expression:liver	RGD	PMID:31211449\|REF_RGD_ID:153350082
APOC2	Dog	Hypercholesterolemia	susceptibility	ISO	RGD:1352001	9068941	associated with Hypertriglyceridemia;DNA:missense mutation: :p.K38Q (human)	RGD	PMID:8490626\|REF_RGD_ID:1601207
APOC2	Dog	Hyperlipoproteinemias	susceptibility	ISO	RGD:1352001	9068941	DNA:missense mutation: :p.L72P (human)	RGD	PMID:16153625\|REF_RGD_ID:1601204
APOC2	Dog	Hyperlipoproteinemias		ISO	RGD:1352001	9068941	protein:increased expression:serum	RGD	PMID:1468157\|REF_RGD_ID:1601208
APOC2	Dog	Hypertriglyceridemia		ISO	RGD:1352001	9068941		RGD	PMID:3944267\|REF_RGD_ID:1601214
APOC2	Dog	Hypertriglyceridemia	susceptibility	ISO	RGD:1352001	9068941		RGD	PMID:7590197\|REF_RGD_ID:1601205
APOC2	Dog	hypobetalipoproteinemia		ISO	RGD:1352001	9068941	protein:decreased expression:plasma	RGD	PMID:2242096\|REF_RGD_ID:1601212
APOC2	Dog	lipid metabolism disorder	no_association	ISO	RGD:1352001	9068941	DNA:missense mutation: :p.K19T (human)	RGD	PMID:7923858\|REF_RGD_ID:1601206
APOC2	Dog	multiple sclerosis		ISO	RGD:1352001	9068941		RGD	PMID:10335523\|REF_RGD_ID:1358408
APOC2	Dog	nephrotic syndrome		ISO	RGD:1352001	9068941	protein:increased expression:serum	RGD	PMID:8366982\|REF_RGD_ID:2313970
APOC2	Dog	obesity		ISO	RGD:1352001	9068941	protein:increased expression:serum	RGD	PMID:9002300\|REF_RGD_ID:1601191
APOC2	Dog	type 2 diabetes mellitus		ISO	RGD:1352001	9068941	protein:increased expression:plasma	RGD	PMID:12733353\|PMID:3757210\|REF_RGD_ID:2313953\|REF_RGD_ID:2313966

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	familial apolipoprotein C-II deficiency		ISO	RGD:1352001	8554872	ClinVar Annotator: match by term: Familial apolipoprotein C-II deficiency	ClinVar	PMID:12783430\|PMID:1349286\|PMID:1569385\|PMID:1628605\|PMID:1782747\|PMID:1971748\|PMID:1990844\|PMID:213719\|PMID:22135386\|PMID:2477392\|PMID:24788417\|PMID:25741868\|PMID:2592354\|PMID:26772541\|PMID:28492532\|PMID:29100061\|PMID:30197986\|PMID:30686043\|PMID:30793526\|PMID:31538826\|PMID:31589614\|PMID:31619059\|PMID:3192518\|PMID:32041611\|PMID:3225819\|PMID:3263393\|PMID:32861330\|PMID:33111339\|PMID:33116287\|PMID:3467353\|PMID:36152419\|PMID:36325899\|PMID:36555767\|PMID:3680515\|PMID:3944267\|PMID:3944271\|PMID:7815420\|PMID:7923858\|PMID:8323539\|PMID:8490626
APOC2	Dog	familial lipoprotein lipase deficiency		ISO	RGD:1352001	8554872	ClinVar Annotator: match by term: C-II ANAPOLIPOPROTEINEMIA	ClinVar	PMID:12783430\|PMID:1349286\|PMID:1628605\|PMID:1782747\|PMID:1971748\|PMID:1990844\|PMID:213719\|PMID:22135386\|PMID:2477392\|PMID:24788417\|PMID:25741868\|PMID:2592354\|PMID:28492532\|PMID:29100061\|PMID:30197986\|PMID:30686043\|PMID:30793526\|PMID:31538826\|PMID:31589614\|PMID:31619059\|PMID:32041611\|PMID:3225819\|PMID:3263393\|PMID:32861330\|PMID:33111339\|PMID:33116287\|PMID:3467353\|PMID:36152419\|PMID:36325899\|PMID:36555767\|PMID:3680515\|PMID:3944267\|PMID:3944271\|PMID:7815420\|PMID:7923858\|PMID:8323539\|PMID:8490626

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	Acute Liver Failure		ISO	RGD:1352001	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:35172013
APOC2	Dog	Drug Eruptions		ISO	RGD:1352001	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:21055120
APOC2	Dog	Experimental Liver Neoplasms		ISO	RGD:1352001	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:11420682

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	familial apolipoprotein C-II deficiency		ISO	RGD:1352001	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	cholesterol efflux	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	chylomicron remnant clearance	involved_in	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	chylomicron remnant clearance	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	chylomicron remodeling	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	high-density lipoprotein particle clearance	involved_in	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	high-density lipoprotein particle clearance	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	lipid catabolic process	involved_in	IEA	UniProtKB-KW:KW-0442	150520179		UniProt	GO_REF:0000043
APOC2	Dog	lipid catabolic process	involved_in	IEA	UniRule:UR001528779	150520179		UniProt	GO_REF:0000104
APOC2	Dog	lipid metabolic process	involved_in	IEA	InterPro:IPR008019	150520179		InterPro	GO_REF:0000002
APOC2	Dog	lipid metabolic process	involved_in	IEA	UniProtKB-KW:KW-0443	150520179		UniProt	GO_REF:0000043
APOC2	Dog	lipid transport	involved_in	IEA	UniProtKB-KW:KW-0445	150520179		UniProt	GO_REF:0000043
APOC2	Dog	lipid transport	involved_in	IEA	UniRule:UR001528779	150520179		UniProt	GO_REF:0000104
APOC2	Dog	lipid transport	involved_in	IEA	InterPro:IPR008019	150520179		InterPro	GO_REF:0000002
APOC2	Dog	lipoprotein catabolic process	involved_in	IBA	PANTHER:PTN002703248\|ZFIN:ZDB-GENE-030131-2168	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	lipoprotein transport		ISO	RGD:2135	9068941		RGD	PMID:4020294\|REF_RGD_ID:1599181
APOC2	Dog	negative regulation of cholesterol transport	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	negative regulation of lipid metabolic process	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	negative regulation of receptor-mediated endocytosis	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	negative regulation of very-low-density lipoprotein particle clearance	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	phospholipid efflux	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	positive regulation of fatty acid biosynthetic process	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	positive regulation of phospholipid catabolic process	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	positive regulation of triglyceride catabolic process	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	positive regulation of very-low-density lipoprotein particle remodeling	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	response to xenobiotic stimulus		ISO	RGD:2135	9068941		RGD	PMID:9888873\|REF_RGD_ID:1599178
APOC2	Dog	triglyceride homeostasis	involved_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	chylomicron	part_of	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	chylomicron	part_of	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	chylomicron	part_of	IEA	UniRule:UR001528779	150520179		UniProt	GO_REF:0000104
APOC2	Dog	chylomicron	part_of	IEA	InterPro:IPR008019	150520179		InterPro	GO_REF:0000002
APOC2	Dog	chylomicron	part_of	IEA	UniProtKB-KW:KW-0162	150520179		UniProt	GO_REF:0000043
APOC2	Dog	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
APOC2	Dog	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
APOC2	Dog	extracellular space	located_in	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	high-density lipoprotein particle	part_of	IEA	UniProtKB-KW:KW-0345	150520179		UniProt	GO_REF:0000043
APOC2	Dog	intermediate-density lipoprotein particle	part_of	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	intermediate-density lipoprotein particle	part_of	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	low-density lipoprotein particle	part_of	IEA	UniProtKB-KW:KW-0427	150520179		UniProt	GO_REF:0000043
APOC2	Dog	low-density lipoprotein particle	part_of	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	low-density lipoprotein particle	part_of	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	low-density lipoprotein particle	part_of	IEA	UniRule:UR001528779	150520179		UniProt	GO_REF:0000104
APOC2	Dog	spherical high-density lipoprotein particle	part_of	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	spherical high-density lipoprotein particle	part_of	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	very-low-density lipoprotein particle	part_of	IEA	UniProtKB-KW:KW-0850	150520179		UniProt	GO_REF:0000043
APOC2	Dog	very-low-density lipoprotein particle	part_of	IEA	UniRule:UR001528779	150520179		UniProt	GO_REF:0000104
APOC2	Dog	very-low-density lipoprotein particle	part_of	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	very-low-density lipoprotein particle	part_of	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	enzyme activator activity	enables	IEA	InterPro:IPR008019	150520179		InterPro	GO_REF:0000002
APOC2	Dog	identical protein binding	enables	ISO	UniProtKB:P02655-PRO_0000002024	9068941	PMID:28229588	IntAct	PMID:28229588
APOC2	Dog	lipase inhibitor activity	enables	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	lipid binding	enables	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	lipoprotein lipase activator activity	enables	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	molecular function activator activity	enables	ISO	RGD:1352001	9068941	PMID:15209504	DisProt	PMID:15209504
APOC2	Dog	phospholipase activator activity	enables	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	phospholipase activator activity	enables	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	phospholipase binding	enables	IBA	PANTHER:PTN002703248\|UniProtKB:P02655	150520179		GO_Central	GO_REF:0000033
APOC2	Dog	phospholipase binding	enables	IEA	UniProtKB:P02655\|ensembl:ENSP00000252490	150520179		Ensembl	GO_REF:0000107
APOC2	Dog	protein binding	enables	ISO	UniProtKB:P49638	9068941	PMID:32296183	IntAct	PMID:32296183

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
APOC2	Dog	altered lipoprotein metabolic pathway		ISO	RGD:1352001	9068941		RGD	PMID:10073946\|REF_RGD_ID:1578471
APOC2	Dog	lipoprotein metabolic pathway		ISO	RGD:1352001	9068941		RGD	PMID:10073946\|REF_RGD_ID:1578471

PMID:2956259	PMID:22301074	PMID:30032202

APOC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	110,504,806 - 110,506,986 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	110,504,815 - 110,506,961 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	109,985,886 - 109,987,967 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	111,034,576 - 111,036,727 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	111,034,585 - 111,036,734 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	110,709,344 - 110,711,427 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	110,344,763 - 110,346,846 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	111,213,632 - 111,215,715 (-)	NCBI		UU_Cfam_GSD_1.0

APOC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	44,946,051 - 44,949,565 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	44,946,035 - 44,949,565 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	45,449,308 - 45,452,822 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	50,141,083 - 50,144,658 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	50,141,082 - 50,144,657	NCBI
Celera	19	42,253,565 - 42,257,132 (+)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	41,879,798 - 41,883,381 (+)	NCBI		HuRef
CHM1_1	19	45,452,071 - 45,455,660 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	47,770,875 - 47,774,393 (+)	NCBI		T2T-CHM13v2.0

Apoc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	19,405,504 - 19,411,866 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	19,405,504 - 19,411,866 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	19,671,579 - 19,677,941 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	19,671,579 - 19,677,941 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	20,256,928 - 20,262,213 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	18,830,106 - 18,836,463 (-)	NCBI		MGSCv36	mm8
Celera	7	17,077,835 - 17,082,947 (-)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	9.94	NCBI

Apoc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	88,457,397 - 88,462,365 (-)	NCBI		GRCr8
mRatBN7.2	1	79,329,429 - 79,334,397 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	79,329,428 - 79,334,476 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	84,724,358 - 84,729,330 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	93,275,674 - 93,280,670 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	86,479,464 - 86,484,436 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	80,589,023 - 80,593,991 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	80,589,023 - 80,594,136 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	81,854,610 - 81,859,580 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,979,034 - 78,984,002 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	73,788,729 - 73,793,701 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Apoc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955555	2,016,217 - 2,021,830 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955555	2,019,547 - 2,021,543 (+)	NCBI	ChiLan1.0	ChiLan1.0

APOC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	51,104,521 - 51,108,310 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	52,976,612 - 52,980,040 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	41,892,954 - 41,896,461 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	50,498,109 - 50,501,877 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

Apoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	17,183,204 - 17,184,690 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936706	1,531,219 - 1,531,921 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

APOC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	51,404,219 - 51,406,302 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	47,285,954 - 47,288,054 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

APOC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	38,406,829 - 38,411,239 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	38,409,641 - 38,410,927 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	17,985,436 - 17,990,512 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Apoc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624907	1,765,481 - 1,769,781 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624907	1,765,467 - 1,769,786 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in APOC2
25 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	4	4	23	22	16	6	4	6	6	29	19	12	10	10


RefSeq Transcripts	NM_001003368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005615740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M17177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000007426 ⟹ ENSCAFP00000006882

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	110,504,815 - 110,506,961 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845011687 ⟹ ENSCAFP00845009125

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	111,034,585 - 111,036,734 (-)	Ensembl

RefSeq Acc Id:

NM_001003368 ⟹ NP_001003368

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	110,504,807 - 110,506,886 (-)	NCBI
Dog10K_Boxer_Tasha	1	109,985,886 - 109,987,967 (-)	NCBI
ROS_Cfam_1.0	1	111,034,577 - 111,036,659 (-)	NCBI
UMICH_Zoey_3.1	1	110,709,344 - 110,711,427 (-)	NCBI
UNSW_CanFamBas_1.0	1	110,344,763 - 110,346,846 (-)	NCBI
UU_Cfam_GSD_1.0	1	111,213,632 - 111,215,715 (-)	NCBI

Sequence:

show sequence

CAGAGTCGGCTTTCTCAGTGGTCCAGGTCTTCCGAAGCCATGGGTACCCGATACCTCCTGGTTCTGTTGCTTGTCCTCCTGGTATTGGGATTTGAGGTCCAGGGGGCCCATGAGTCCCAGCAAGATGA
AACCACCAGCTCCGCCCTGCTCACCCAGATGCAGGAATCACTCTACAGTTACTGGGGCACAGCCAGATCGGCTGCCGAGGACCTGTACAAGAAGGCATACCCAACTACCATGGATGAGAAAATCAGGG
ACATATACAGCAAAAGCACAGCAGCTGTGAGCACTTACGCAGGGATTTTCACTGACCAGCTACTTTCTATGCTGAAGGGAGACTCGTAACAGCTGAGCCCCGATCGTGGGGGAGGGGAGAGTCCAGAC
CCCCCACTTCTCAGCACTGTCAGCATCTTGCTCCAGTGCTAGTCTGTCTTCTTATAAATAAATACATTTAAAAAGCC

hide sequence

RefSeq Acc Id:

XM_038653453 ⟹ XP_038509381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	111,034,576 - 111,036,727 (-)	NCBI

RefSeq Acc Id:

XM_038653454 ⟹ XP_038509382

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	111,034,576 - 111,036,174 (-)	NCBI


Protein RefSeqs	NP_001003368	(Get FASTA)	NCBI Sequence Viewer
	XP_038509381	(Get FASTA)	NCBI Sequence Viewer
	XP_038509382	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA30829	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000006882.3
	ENSCAFP00030003475.1
	ENSCAFP00040018404.1
	ENSCAFP00845009125
	ENSCAFP00845009125.1
GenBank Protein	P12278	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001003368 ⟸ NM_001003368
- Peptide Label:	precursor
- UniProtKB:	P12278 (UniProtKB/Swiss-Prot), A0A8C0KH95 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTRYLLVLLLVLLVLGFEVQGAHESQQDETTSSALLTQMQESLYSYWGTARSAAEDLYKKAYPTTMDEKIRDIYSKSTAAVSTYAGIFTDQLLSMLKGDS hide sequence

Ensembl Acc Id:

ENSCAFP00000006882 ⟸ ENSCAFT00000007426

RefSeq Acc Id:	XP_038509381 ⟸ XM_038653453
- Peptide Label:	isoform X1
- UniProtKB:	P12278 (UniProtKB/Swiss-Prot), A0A8C0KH95 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038509382 ⟸ XM_038653454
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCAFP00845009125 ⟸ ENSCAFT00845011687

RGD ID:

13682252

Promoter ID:

EPDNEW_C321

Type:

single initiation site

Name:

APOC2_1

Description:

Apolipoprotein C-II Proapolipoprotein C-II

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	110,505,919 - 110,505,979	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000004610	Ensembl, UniProtKB/Swiss-Prot
	ENSCAFG00030002139	UniProtKB/Swiss-Prot
	ENSCAFG00040011476	UniProtKB/Swiss-Prot
	ENSCAFG00845006579	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00000007426.5	UniProtKB/Swiss-Prot
	ENSCAFT00030003915.1	UniProtKB/Swiss-Prot
	ENSCAFT00040021204.1	UniProtKB/Swiss-Prot
	ENSCAFT00845011687	ENTREZGENE
	ENSCAFT00845011687.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.1440.10	UniProtKB/Swiss-Prot
InterPro	Apo-CII	UniProtKB/Swiss-Prot
	ApoC-II_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	cfa:442969	UniProtKB/Swiss-Prot
NCBI Gene	APOC2	ENTREZGENE
PANTHER	APOLIPOPROTEIN C-II	UniProtKB/Swiss-Prot
	PTHR16566	UniProtKB/Swiss-Prot
Pfam	Apo-CII	UniProtKB/Swiss-Prot
UniProt	A0A8C0KH95	ENTREZGENE
	A0A8C0LY94_CANLF	UniProtKB/TrEMBL
	APOC2_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:56913	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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