APOC2 (apolipoprotein C2) - Rat Genome Database

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Gene: APOC2 (apolipoprotein C2) Canis lupus familiaris
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Symbol: APOC2
Name: apolipoprotein C2
RGD ID: 12254569
Description: ENCODES a protein that exhibits identical protein binding (ortholog); molecular function activator activity (ortholog); INVOLVED IN lipoprotein transport (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Coronary Disease (ortholog); diabetes mellitus (ortholog); FOUND IN chylomicron (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Apo-CII; ApoC-II; APOCII; apolipoprotein C-II
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,504,806 - 110,506,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,504,815 - 110,506,961 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,985,886 - 109,987,967 (-)NCBI
ROS_Cfam_1.01111,034,576 - 111,036,727 (-)NCBI
ROS_Cfam_1.0 Ensembl1111,034,585 - 111,036,734 (-)Ensembl
UMICH_Zoey_3.11110,709,344 - 110,711,427 (-)NCBI
UNSW_CanFamBas_1.01110,344,763 - 110,346,846 (-)NCBI
UU_Cfam_GSD_1.01111,213,632 - 111,215,715 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:2956259  


Genomics

Comparative Map Data
APOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,504,806 - 110,506,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,504,815 - 110,506,961 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,985,886 - 109,987,967 (-)NCBI
ROS_Cfam_1.01111,034,576 - 111,036,727 (-)NCBI
ROS_Cfam_1.0 Ensembl1111,034,585 - 111,036,734 (-)Ensembl
UMICH_Zoey_3.11110,709,344 - 110,711,427 (-)NCBI
UNSW_CanFamBas_1.01110,344,763 - 110,346,846 (-)NCBI
UU_Cfam_GSD_1.01111,213,632 - 111,215,715 (-)NCBI
APOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,946,051 - 44,949,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1944,946,035 - 44,949,565 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,449,308 - 45,452,822 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,141,083 - 50,144,658 (+)NCBINCBI36hg18NCBI36
Build 341950,141,082 - 50,144,657NCBI
Celera1942,253,565 - 42,257,132 (+)NCBI
Cytogenetic Map19q13.32NCBI
HuRef1941,879,798 - 41,883,381 (+)NCBIHuRef
CHM1_11945,452,071 - 45,455,660 (+)NCBICHM1_1
T2T-CHM13v2.01947,770,875 - 47,774,393 (+)NCBI
Apoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,405,504 - 19,411,866 (-)NCBIGRCm39mm39
GRCm39 Ensembl719,405,504 - 19,411,866 (-)Ensembl
GRCm38719,671,579 - 19,677,941 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,671,579 - 19,677,941 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,256,928 - 20,262,213 (-)NCBIGRCm37mm9NCBIm37
MGSCv36718,830,106 - 18,836,463 (-)NCBImm8
Celera717,077,835 - 17,082,947 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.94NCBI
Apoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2179,329,429 - 79,334,397 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl179,329,428 - 79,334,476 (-)Ensembl
Rnor_6.0180,589,023 - 80,593,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,589,023 - 80,594,136 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,854,610 - 81,859,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,979,034 - 78,984,002 (-)NCBIRGSC3.4rn4RGSC3.4
Celera173,788,729 - 73,793,701 (-)NCBICelera
Cytogenetic Map1q21NCBI
Apoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555552,016,217 - 2,021,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555552,019,547 - 2,021,543 (+)NCBIChiLan1.0ChiLan1.0
APOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11950,498,109 - 50,501,877 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01941,892,954 - 41,896,461 (+)NCBIMhudiblu_PPA_v0panPan3
Apoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,183,204 - 17,184,690 (+)NCBI
SpeTri2.0NW_0049367061,531,219 - 1,531,921 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1651,404,219 - 51,406,302 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,285,954 - 47,288,054 (+)NCBISscrofa10.2Sscrofa10.2susScr3
APOC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,406,829 - 38,411,239 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl638,409,641 - 38,410,927 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607317,985,436 - 17,990,512 (+)NCBIVero_WHO_p1.0
Apoc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,765,481 - 1,769,781 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249071,765,467 - 1,769,786 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 6 6 6
Medium
Low 1 3 2 1 2 6
Below cutoff 3 1 16 2 6 5 12 4 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000007426   ⟹   ENSCAFP00000006882
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1110,504,815 - 110,506,961 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845011687   ⟹   ENSCAFP00845009125
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1111,034,585 - 111,036,734 (-)Ensembl
RefSeq Acc Id: NM_001003368   ⟹   NP_001003368
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11110,504,807 - 110,506,886 (-)NCBI
Dog10K_Boxer_Tasha1109,985,886 - 109,987,967 (-)NCBI
ROS_Cfam_1.01111,034,577 - 111,036,659 (-)NCBI
UMICH_Zoey_3.11110,709,344 - 110,711,427 (-)NCBI
UNSW_CanFamBas_1.01110,344,763 - 110,346,846 (-)NCBI
UU_Cfam_GSD_1.01111,213,632 - 111,215,715 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038653453   ⟹   XP_038509381
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01111,034,576 - 111,036,727 (-)NCBI
RefSeq Acc Id: XM_038653454   ⟹   XP_038509382
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01111,034,576 - 111,036,174 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001003368 (Get FASTA)   NCBI Sequence Viewer  
  XP_038509381 (Get FASTA)   NCBI Sequence Viewer  
  XP_038509382 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA30829 (Get FASTA)   NCBI Sequence Viewer  
  P12278 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003368   ⟸   NM_001003368
- Peptide Label: precursor
- UniProtKB: P12278 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000006882   ⟸   ENSCAFT00000007426
RefSeq Acc Id: XP_038509381   ⟸   XM_038653453
- Peptide Label: isoform X1
- UniProtKB: P12278 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038509382   ⟸   XM_038653454
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCAFP00845009125   ⟸   ENSCAFT00845011687

Promoters
RGD ID:13682252
Promoter ID:EPDNEW_C321
Type:single initiation site
Name:APOC2_1
Description:Apolipoprotein C-II Proapolipoprotein C-II
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11110,505,919 - 110,505,979EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004610 Ensembl
  ENSCAFG00030002139 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040011476 UniProtKB/Swiss-Prot
  ENSCAFG00845006579 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSCAFP00030003475 UniProtKB/Swiss-Prot
  ENSCAFP00030003487.1 UniProtKB/TrEMBL
  ENSCAFP00040018404 UniProtKB/Swiss-Prot
  ENSCAFP00845009125 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00030003915 UniProtKB/Swiss-Prot
  ENSCAFT00030003932.1 UniProtKB/TrEMBL
  ENSCAFT00040021204 UniProtKB/Swiss-Prot
  ENSCAFT00845011687 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1440.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Apo-CII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ApoC-II_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:442969 UniProtKB/Swiss-Prot
NCBI Gene APOC2 ENTREZGENE
PANTHER PTHR16566 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Apo-CII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0LY94_CANLF UniProtKB/TrEMBL
  APOC2_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:56913 ENTREZGENE