TRIM8 (tripartite motif containing 8)

Gene: TRIM8 (tripartite motif containing 8) Canis lupus familiaris

Analyze

Symbol:

TRIM8

Name:

tripartite motif containing 8

RGD ID:

12064349

Description:

ENCODES a protein that exhibits mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN positive regulation of protein localization to nucleus (ortholog); stem cell population maintenance (ortholog); ASSOCIATED WITH electroclinical syndrome (ortholog); epilepsy (ortholog); Focal Segmental Glomerulosclerosis and Neurodevelopmental Syndrome (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase TRIM8; probable E3 ubiquitin-protein ligase TRIM8; tripartite motif-containing protein 8

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	15,124,310 - 15,138,660 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	15,123,348 - 15,146,355 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	15,295,973 - 15,310,544 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	15,597,872 - 15,612,454 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	15,597,467 - 15,612,445 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	15,142,279 - 15,156,856 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	15,182,036 - 15,196,628 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	15,314,070 - 15,328,679 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

electroclinical syndrome (ISO)

epilepsy (ISO)

Focal Segmental Glomerulosclerosis and Neurodevelopmental Syndrome (ISO)

genetic disease (ISO)

nevoid basal cell carcinoma syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical NF-kappaB signal transduction (IEA)

innate immune response (IEA)

negative regulation of viral entry into host cell (IEA)

negative regulation of viral transcription (IEA)

positive regulation of autophagy (IEA)

positive regulation of canonical NF-kappaB signal transduction (IEA)

positive regulation of DNA-templated transcription (IEA)

positive regulation of protein localization to nucleus (IEA,ISO)

protein K63-linked ubiquitination (IEA)

stem cell population maintenance (IEA,ISO)

suppression of viral release by host (IEA)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA)

membrane (IEA)

nucleus (IEA)

PML body (IEA)

Molecular Function

identical protein binding (IEA)

metal ion binding (IEA)

mitogen-activated protein kinase kinase kinase binding (ISO)

protein binding (ISO)

protein homodimerization activity (IEA)

transcription coactivator activity (IEA)

ubiquitin protein ligase activity (IEA)

References

Genomics

Comparative Map Data

TRIM8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	15,124,310 - 15,138,660 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	15,123,348 - 15,146,355 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	15,295,973 - 15,310,544 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	15,597,872 - 15,612,454 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	15,597,467 - 15,612,445 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	15,142,279 - 15,156,856 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	15,182,036 - 15,196,628 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	15,314,070 - 15,328,679 (+)	NCBI		UU_Cfam_GSD_1.0

TRIM8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	102,644,479 - 102,658,319 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	102,642,503 - 102,658,318 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	104,404,236 - 104,418,076 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	104,394,242 - 104,408,066 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	104,394,355 - 104,408,064	NCBI
Celera	10	98,145,270 - 98,159,115 (+)	NCBI		Celera
Cytogenetic Map	10	q24.32	NCBI
HuRef	10	98,038,827 - 98,052,661 (+)	NCBI		HuRef
CHM1_1	10	104,688,022 - 104,701,849 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	103,530,264 - 103,544,111 (+)	NCBI		T2T-CHM13v2.0

Trim8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	46,490,087 - 46,504,894 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	46,490,141 - 46,505,287 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	46,501,648 - 46,516,805 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	46,501,702 - 46,516,848 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	46,576,138 - 46,590,945 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	46,555,610 - 46,569,672 (+)	NCBI		MGSCv36	mm8
Celera	19	47,265,345 - 47,280,149 (+)	NCBI		Celera
Cytogenetic Map	19	C3	NCBI
cM Map	19	38.92	NCBI

Trim8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	255,311,039 - 255,325,937 (+)	NCBI		GRCr8
mRatBN7.2	1	245,369,632 - 245,384,513 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	245,369,632 - 245,384,513 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	253,497,013 - 253,512,110 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	260,189,784 - 260,204,935 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	252,841,090 - 252,856,181 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	266,255,797 - 266,270,694 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	266,255,797 - 266,270,694 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	273,686,719 - 273,701,616 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	251,724,890 - 251,739,787 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	251,988,330 - 252,002,878 (+)	NCBI
Celera	1	241,152,131 - 241,166,997 (+)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

Trim8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955485	7,782,794 - 7,797,022 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955485	7,784,625 - 7,798,131 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIM8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	114,525,712 - 114,540,343 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	114,531,491 - 114,545,666 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	99,242,187 - 99,256,342 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	102,707,203 - 102,720,565 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	102,707,199 - 102,720,565 (+)	Ensembl	panpan1.1		panPan2

Trim8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	31,641,667 - 31,655,616 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	3,244,405 - 3,259,218 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	3,244,888 - 3,259,042 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	113,636,832 - 113,652,372 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	113,637,437 - 113,652,577 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	123,491,837 - 123,506,692 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	95,671,622 - 95,686,701 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	95,672,648 - 95,689,247 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	56,785,209 - 56,799,410 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624831	2,020,227 - 2,032,099 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624831	2,020,185 - 2,031,001 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in TRIM8
119 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	4	3	20	5	6	5	6		12		10	6
Low	1	2	2	1		1		6		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014109051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038440422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038515044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038578649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038642833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000016244 ⟹ ENSCAFP00000015028

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	28	15,123,835 - 15,138,447 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000085251 ⟹ ENSCAFP00000053685

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	28	15,123,348 - 15,146,355 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000092393 ⟹ ENSCAFP00000062056

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	28	15,123,348 - 15,138,447 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845044374 ⟹ ENSCAFP00845034772

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	28	15,597,467 - 15,612,238 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845044430 ⟹ ENSCAFP00845034816

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	28	15,597,470 - 15,612,445 (+)	Ensembl

RefSeq Acc Id:

XM_014109051 ⟹ XP_013964526

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	28	15,124,310 - 15,138,660 (+)	NCBI
Dog10K_Boxer_Tasha	28	15,295,973 - 15,310,544 (+)	NCBI

Sequence:

show sequence

TCTCTCCTCTGGGGGGCAGGCGCGCGGAAGGCGCTGGTGATTGAGCGACTGTCGCGGCGGCCTG
GGGCCGGAGCTCGGGGCTCGGTGGGCCTGCAGCTGCACGGGACGGACCCCCAGAGTTGGGCAGT
CGGGGAGGCCTGCCCGGGCCCCCTGCCCGCAGCCGCCATGGCGGAGAATTGGAAGAACTGCTTC
GAGGAGGAGCTCATTTGCCCCATCTGCCTGCACGTCTTCGTGGAGCCGGTGCAATTGCCGTGCA
AACACAACTTCTGCCGGGGCTGCATTGGCGAGGCGTGGGCCAAGGACAGCGGCCTGGTGCGCTG
CCCGGAGTGTAACCAGGCCTACAACCAGAAGCCGGGCCTGGAGAAGAACCTGAAGCTCACCAAC
ATCGTGGAGAAGTTCAACGCCCTGCACGTGGAGAAGCCGCCGGCGGCGCTGCACTGCGTGTTCT
GCCGCCGCGGCCCCCCGCTGCCCGCGCAGAAGGTCTGCCTGCGCTGCGAGGCGCCCTGCTGCCA
GTCCCACGTGCAGACGCACCTGCAGCAGCCCTCCACCGCCCGCGGGCACCTCCTGGTGGAGGCG
GACGACGTGCGGGCTTGGAGCTGCCCCCAGCACAACGCCTACCGCCTCTACCACTGTGAGGCCG
AGCAGGTGGCCGTGTGCCAGTACTGCTGCTACTACAGCGGTGCGCATCAGGGACACTCGGTGTG
CGACGTGGAGATCCGGAGGAATGAGATCCGGAAGATGCTGATGAAGCAACAGGACCGTCTGGAG
GAGCGAGAGCAGGATATTGAAGACCAGCTGTACAAACTTGAGTCAGACAAGCGCTTGGTGGAGG
AGAAGGTGAGCCAGCTGAAGGAGGAGGTGCGGCTGCAGTATGAAAAGCTGCACCAGCTGCTGGA
TGAGGACCTGCGGCAGACGGTTGAGGTCCTGGACAAGGCCCAGGCCAAGTTCTGCAGCGAGAAC
GCAGCGCAGGCGCTGCACCTTGGGGAGCGCATGCAGGAGGCCAAGAAGCTGCTGGGCTCCCTGC
AGCTGCTCTTCGACAAGACGGAGGACGTCAGCTTCATGAAGAACACCAAGTCTGTGAAAATCCT
AATGGACAGGACCCAGACCTGCACGGGCAGCAGCCTTTCTCCCCCTAAGATCGGCCACCTGAAC
TCCAAGCTCTTCCTGAATGAGGTGGCCAAGAAGGAGAAGCAGCTGCGGAAGATGCTAGAAGGCC
CCTTCAGCACACCGGTGCCCTTCCTGCAGAGCGTCCCCCTGTATCCTTGTGGCGTGAGCAGCTC
TGGGGCGGAGAAGCGCAAGCACTCAACGGCCTTCCCGGAGGCCAGTTTCCTAGAGACGTCGTCA
GGCCCCGTGGGCAGCCAATATGGGGCAGCAGGCACAGCCAGCAGCGAGGGCCAGTCAGGGCAGC
CCCTGGGGCCCTGCAGCTCCACGCAGCACTTGGTGGCCCTGCCGGGCGGCGCCCAACCAGTGCA
CTCAAGTCCTGTGTTCCCCCCATCACAGTATCCCAATGGCTCTGCCACCCAGCAGCCCATGCTC
CCCCAGTATGGCGGCCGCAAGATTCTCGTCTGTTCTGTGGACAACTGTTACTGTTCTTCCGTGG
CCAACCATGGTGGCCACCAGCCCTACCCCCGCTCCGGCCATTTTCCCTGGACAGTGCCCTCGCA
GGAGTATTCACACCCGCTCCCGCCCACACCCTCCGTCCCCCAGTCCCTTCCTGGCCTGGCGGTC
AGAGACTGGCTCGACGCCTCCCAGCAGCCTGGTCACCAGGATTTCTACAGGGTGTATGGGCAGC
CATCCACCAAACACTACGTGACGAGCTAACGCCACGCAGGCAGTGGGGCGCTGGGGAATCTTCC
CCCGCACCCTCAGTGGCTCGGGAATTATGCATCCAGAGACCTGTCCTTCCACTTCCTGTCTCCC
CTCCCTCCCTTCTTCATCTCCCCCAAGTCTTTTCCTTTTGGATTTTGTTTTGTTTGGGGCTTTT
TTTTTTTTTTTTTTTTTTTTAAATGAATCTCCTGGACACAGAGGCGACAGTGAGAGCTGGCCTG
GCCTGGGCTACAGGTGGCCCTGGAGTTGGGAAAGCATCTACTTCAAGGCATTGAGCTTTCTCTC
TGTCCTTTTTTCTTCCACTCCTTCTCCTTCCCACCTCCATGGCTGGAAGAAGCCTCAGCTTCCC
CTAAAGCCTTGGGGGGGAATCTAACCCTCTGACCCAGCCCTGGGAGGAAGGACCAGTGGTGCCC
ACCCCCTGGCCTATTTCTCTCGTTTTTCTTTTGGACAGTTTGATCACTGACTGAGTAAGAAATG
ACCTGTAGATCGTGGGTTGTTTTTTTGTTTTTGTTTTTTTGTTTTTTAATTTTTTTTAAACCAA
GAATGATTTCTCCTGCTTCCTTCTTCTCAACATCCTCCCAGATGGAGTTCAAAGGCCACTTCTC
AAGCAGCTTTTGGCACCTTCAGCCTCAGAGTGGAATCTTAAAGACAGGAACCCCATGTCCAGGA
AAGGGGAAAAGGAACTTTGCCAATGATAGTGACCACAGCAAAAGCAAATAATAATAATATTAAT
AATAATAAAGAGAAATAAAAGAAATAATAAAATAAAAAAAAACATAGCACAGCCCTTGTTGAGG
TGAGTGGGGGAGGAGGGGCTGCCCCAAGTTGGGTCCTTGCCTGGATTTTGACACAGCAACTTCC
TGTAGTGAGCACTTTGTATGAATCGTGGACTTCCTGTTCTCAAGGCGCAGGTATTTATTCTGTA
ATCTCTCTAGAGCACACACCGAAATCCAACCTTCTAATAAACATAATGGCGCAGTCCCAC

hide sequence

RefSeq Acc Id:

XM_038440422 ⟹ XP_038296350

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	28	15,597,872 - 15,612,454 (+)	NCBI

RefSeq Acc Id:

XM_038515044 ⟹ XP_038370972

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	28	15,142,279 - 15,156,856 (+)	NCBI

RefSeq Acc Id:

XM_038578649 ⟹ XP_038434577

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	28	15,314,070 - 15,328,679 (+)	NCBI

RefSeq Acc Id:

XM_038642833 ⟹ XP_038498761

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	28	15,182,036 - 15,196,628 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013964526	(Get FASTA)	NCBI Sequence Viewer
	XP_038296350	(Get FASTA)	NCBI Sequence Viewer
	XP_038370972	(Get FASTA)	NCBI Sequence Viewer
	XP_038434577	(Get FASTA)	NCBI Sequence Viewer
	XP_038498761	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000015028.5
	ENSCAFP00000062056.2
	ENSCAFP00030039531.1
	ENSCAFP00030039540.1
	ENSCAFP00040038232.1
	ENSCAFP00040038247.1
	ENSCAFP00845034772.1
	ENSCAFP00845034816
	ENSCAFP00845034816.1

RefSeq Acc Id:

XP_013964526 ⟸ XM_014109051

- UniProtKB:

A0A8C0RSX6 (UniProtKB/TrEMBL), A0A8C0QYE8 (UniProtKB/TrEMBL), A0A8I3PKC4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPG
LEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPST
ARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKM
LMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVSQLKEEVRLQYEKLHQLLDEDLRQTVEVLDK
AQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTGSSL
SPPKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVSSSGAEKRKHSTAFP
EASFLETSSGPVGSQYGAAGTASSEGQSGQPLGPCSSTQHLVALPGGAQPVHSSPVFPPSQYPN
GSATQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQEYSHPLPPTPSV
PQSLPGLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS

hide sequence

RefSeq Acc Id:

ENSCAFP00000062056 ⟸ ENSCAFT00000092393

RefSeq Acc Id:

ENSCAFP00000015028 ⟸ ENSCAFT00000016244

RefSeq Acc Id:

ENSCAFP00000053685 ⟸ ENSCAFT00000085251

RefSeq Acc Id:

XP_038370972 ⟸ XM_038515044

RefSeq Acc Id:

XP_038498761 ⟸ XM_038642833

RefSeq Acc Id:	XP_038296350 ⟸ XM_038440422
- UniProtKB:	A0A8C0RSX6 (UniProtKB/TrEMBL), A0A8C0QYE8 (UniProtKB/TrEMBL), A0A8I3PKC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038434577 ⟸ XM_038578649
- UniProtKB:	A0A8C0QYE8 (UniProtKB/TrEMBL), A0A8C0RSX6 (UniProtKB/TrEMBL), A0A8I3PKC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845034772 ⟸ ENSCAFT00845044374

RefSeq Acc Id:

ENSCAFP00845034816 ⟸ ENSCAFT00845044430

Protein Domains

RING-type

Promoters

RGD ID:

13688317

Promoter ID:

EPDNEW_C6384

Type:

single initiation site

Name:

TRIM8_1

Description:

tripartite motif containing 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	28	15,124,023 - 15,124,083	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010232	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030024614	UniProtKB/TrEMBL
	ENSCAFG00040023547	UniProtKB/TrEMBL
	ENSCAFG00845025148	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016244.5	UniProtKB/TrEMBL
	ENSCAFT00000092393.2	UniProtKB/TrEMBL
	ENSCAFT00030045276.1	UniProtKB/TrEMBL
	ENSCAFT00030045286.1	UniProtKB/TrEMBL
	ENSCAFT00040043812.1	UniProtKB/TrEMBL
	ENSCAFT00040043827.1	UniProtKB/TrEMBL
	ENSCAFT00845044374.1	UniProtKB/TrEMBL
	ENSCAFT00845044430	ENTREZGENE
	ENSCAFT00845044430.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
	4.10.830.40	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	Znf-RING_euk	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
KEGG Report	cfa:486863	UniProtKB/TrEMBL
NCBI Gene	TRIM8	ENTREZGENE
PANTHER	B-BOX DOMAIN CONTAINING	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE TRIM8	UniProtKB/TrEMBL
Pfam	zf-RING_UBOX	UniProtKB/TrEMBL
PROSITE	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	RING	UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A8C0QYE8	ENTREZGENE
	A0A8C0RSX6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TL33_CANLF	UniProtKB/TrEMBL
	A0A8I3PKC4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PTT9_CANLF	UniProtKB/TrEMBL
UniProt Secondary	A0A8P0NC85	UniProtKB/TrEMBL
VGNC ID	VGNC:47839	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM