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Gene: Trim8 (tripartite motif-containing 8) Mus musculus
Symbol: Trim8
Name: tripartite motif-containing 8
Description: Predicted to have protein homodimerization activity. Involved in several processes, including negative regulation of viral process; positive regulation of protein localization to nucleus; and stem cell population maintenance. Localizes to the cytosol and nucleus. Is expressed in cerebellum layer; female reproductive system; and urinary system. Orthologous to human TRIM8 (tripartite motif containing 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408830; BB006755; GERP; glioblastoma-expressed RING finger protein; probable E3 ubiquitin-protein ligase TRIM8; ring finger protein 27; RING-type E3 ubiquitin transferase TRIM8; Rnf27; tripartite motif protein 8; tripartite motif-containing protein 8
Homo sapiens (human) : TRIM8 (tripartite motif containing 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Trim8 (tripartite motif-containing 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim8 (tripartite motif containing 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM8 (tripartite motif containing 8)
Canis lupus familiaris (dog) : TRIM8 (tripartite motif containing 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim8 (tripartite motif containing 8)
Sus scrofa (pig) : TRIM8 (tripartite motif containing 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1946,501,702 - 46,516,848 (+)Ensembl
GRCm381946,501,648 - 46,516,805 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371946,576,138 - 46,590,945 (+)NCBIGRCm37mm9NCBIm37
MGSCv361946,555,610 - 46,569,672 (+)NCBImm8
Celera1947,265,345 - 47,280,149 (+)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Trim8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319836
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.