Trim8 (tripartite motif containing 8) - Rat Genome Database

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Gene: Trim8 (tripartite motif containing 8) Ictidomys tridecemlineatus
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Symbol: Trim8
Name: tripartite motif containing 8
RGD ID: 12524811
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of viral entry into host cell (ortholog); negative regulation of viral release from host cell (ortholog); ASSOCIATED WITH electroclinical syndrome (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); PML body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase TRIM8; probable E3 ubiquitin-protein ligase TRIM8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,641,667 - 31,655,616 (-)NCBI
SpeTri2.0NW_0049366003,244,888 - 3,259,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Trim8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,641,667 - 31,655,616 (-)NCBI
SpeTri2.0NW_0049366003,244,888 - 3,259,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10102,644,479 - 102,658,318 (+)EnsemblGRCh38hg38GRCh38
GRCh3810102,644,479 - 102,658,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710104,404,236 - 104,418,076 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610104,394,242 - 104,408,066 (+)NCBINCBI36hg18NCBI36
Build 3410104,394,355 - 104,408,064NCBI
Celera1098,145,270 - 98,159,115 (+)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1098,038,827 - 98,052,661 (+)NCBIHuRef
CHM1_110104,688,022 - 104,701,849 (+)NCBICHM1_1
Trim8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391946,490,087 - 46,504,894 (+)NCBIGRCm39mm39
GRCm39 Ensembl1946,490,141 - 46,505,287 (+)Ensembl
GRCm381946,501,648 - 46,516,805 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1946,501,702 - 46,516,848 (+)EnsemblGRCm38mm10GRCm38
MGSCv371946,576,138 - 46,590,945 (+)NCBIGRCm37mm9NCBIm37
MGSCv361946,555,610 - 46,569,672 (+)NCBImm8
Celera1947,265,345 - 47,280,149 (+)NCBICelera
Cytogenetic Map19C3NCBI
Trim8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21245,369,632 - 245,384,513 (+)NCBI
Rnor_6.0 Ensembl1266,255,797 - 266,270,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01266,255,797 - 266,270,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01273,686,719 - 273,701,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,724,890 - 251,739,787 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,988,330 - 252,002,878 (+)NCBI
Celera1241,152,131 - 241,166,997 (+)NCBICelera
Cytogenetic Map1q54NCBI
Trim8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,782,794 - 7,797,022 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554857,784,625 - 7,798,131 (-)NCBIChiLan1.0ChiLan1.0
TRIM8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110102,707,203 - 102,720,565 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10102,707,199 - 102,720,565 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01099,242,187 - 99,256,342 (+)NCBIMhudiblu_PPA_v0panPan3
TRIM8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,124,310 - 15,138,660 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,123,348 - 15,146,355 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2815,295,973 - 15,310,544 (+)NCBI
ROS_Cfam_1.02815,597,872 - 15,612,454 (+)NCBI
UMICH_Zoey_3.12815,142,279 - 15,156,856 (+)NCBI
UNSW_CanFamBas_1.02815,182,036 - 15,196,628 (+)NCBI
UU_Cfam_GSD_1.02815,314,070 - 15,328,679 (+)NCBI
TRIM8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14113,637,585 - 113,652,577 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114113,637,437 - 113,652,577 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214123,491,837 - 123,506,692 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1995,671,622 - 95,686,701 (+)NCBI
ChlSab1.1 Ensembl995,672,648 - 95,689,247 (+)Ensembl
Vero_WHO_p1.0NW_02366604856,785,209 - 56,799,410 (+)NCBI
Trim8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248312,020,185 - 2,031,001 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005333616   ⟹   XP_005333673
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721331,641,667 - 31,655,616 (-)NCBI
SpeTri2.0NW_0049366003,244,888 - 3,259,042 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040272037   ⟹   XP_040127971
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721331,641,668 - 31,655,616 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005333673 (Get FASTA)   NCBI Sequence Viewer  
  XP_040127971 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3264168 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005333673   ⟸   XM_005333616
- Peptide Label: isoform X1
- UniProtKB: I3MBB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040127971   ⟸   XM_040272037
- Peptide Label: isoform X2
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008270 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007403 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008263 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Trim8 ENTREZGENE
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
UniProt I3MBB3 ENTREZGENE, UniProtKB/TrEMBL