TRIM8 (tripartite motif containing 8) - Rat Genome Database

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Gene: TRIM8 (tripartite motif containing 8) Chlorocebus sabaeus
Analyze
Symbol: TRIM8
Name: tripartite motif containing 8
RGD ID: 18345700
Description: ENCODES a protein that exhibits mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN positive regulation of protein localization to nucleus (ortholog); stem cell population maintenance (ortholog); ASSOCIATED WITH electroclinical syndrome (ortholog); epilepsy (ortholog); Focal Segmental Glomerulosclerosis and Neurodevelopmental Syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase TRIM8; probable E3 ubiquitin-protein ligase TRIM8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1995,671,622 - 95,686,701 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl995,672,648 - 95,689,247 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604856,785,209 - 56,799,410 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
TRIM8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1995,671,622 - 95,686,701 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl995,672,648 - 95,689,247 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604856,785,209 - 56,799,410 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TRIM8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810102,644,479 - 102,658,319 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10102,642,503 - 102,658,318 (+)EnsemblGRCh38hg38GRCh38
GRCh3710104,404,236 - 104,418,076 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610104,394,242 - 104,408,066 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410104,394,355 - 104,408,064NCBI
Celera1098,145,270 - 98,159,115 (+)NCBICelera
Cytogenetic Map10q24.32NCBI
HuRef1098,038,827 - 98,052,661 (+)NCBIHuRef
CHM1_110104,688,022 - 104,701,849 (+)NCBICHM1_1
T2T-CHM13v2.010103,530,264 - 103,544,111 (+)NCBIT2T-CHM13v2.0
Trim8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391946,490,087 - 46,504,894 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1946,490,141 - 46,505,287 (+)EnsemblGRCm39 Ensembl
GRCm381946,501,648 - 46,516,805 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1946,501,702 - 46,516,848 (+)EnsemblGRCm38mm10GRCm38
MGSCv371946,576,138 - 46,590,945 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361946,555,610 - 46,569,672 (+)NCBIMGSCv36mm8
Celera1947,265,345 - 47,280,149 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.92NCBI
Trim8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81255,311,039 - 255,325,937 (+)NCBIGRCr8
mRatBN7.21245,369,632 - 245,384,513 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,369,632 - 245,384,513 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1253,497,013 - 253,512,110 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,189,784 - 260,204,935 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01252,841,090 - 252,856,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01266,255,797 - 266,270,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,255,797 - 266,270,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01273,686,719 - 273,701,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,724,890 - 251,739,787 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11251,988,330 - 252,002,878 (+)NCBI
Celera1241,152,131 - 241,166,997 (+)NCBICelera
Cytogenetic Map1q54NCBI
Trim8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,782,794 - 7,797,022 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554857,784,625 - 7,798,131 (-)NCBIChiLan1.0ChiLan1.0
TRIM8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28114,525,712 - 114,540,343 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110114,531,491 - 114,545,666 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01099,242,187 - 99,256,342 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110102,707,203 - 102,720,565 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10102,707,199 - 102,720,565 (+)Ensemblpanpan1.1panPan2
TRIM8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,124,310 - 15,138,660 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,123,348 - 15,146,355 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2815,295,973 - 15,310,544 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02815,597,872 - 15,612,454 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2815,597,467 - 15,612,445 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12815,142,279 - 15,156,856 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02815,182,036 - 15,196,628 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02815,314,070 - 15,328,679 (+)NCBIUU_Cfam_GSD_1.0
Trim8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,641,667 - 31,655,616 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366003,244,405 - 3,259,218 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366003,244,888 - 3,259,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14113,636,832 - 113,652,372 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114113,637,437 - 113,652,577 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214123,491,837 - 123,506,692 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Trim8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248312,020,227 - 2,032,099 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248312,020,185 - 2,031,001 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 34 5 52
Low 2 15 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007963982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000003445   ⟹   ENSCSAP00000001721
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl995,672,648 - 95,689,247 (+)Ensembl
RefSeq Acc Id: XM_007963982   ⟹   XP_007962173
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1995,671,622 - 95,686,701 (+)NCBI
Vero_WHO_p1.0NW_02366604856,785,209 - 56,799,410 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007962173 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001721
  ENSCSAP00000001721.1
Reference Protein Sequences
RefSeq Acc Id: XP_007962173   ⟸   XM_007963982
- UniProtKB: A0A0D9QZD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000001721   ⟸   ENSCSAT00000003445


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005411 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003445.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf-RING_euk UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report csab:103216442 UniProtKB/TrEMBL
NCBI Gene TRIM8 ENTREZGENE
PANTHER B-BOX DOMAIN CONTAINING UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE TRIM8 UniProtKB/TrEMBL
Pfam zf-RING_UBOX UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
UniProt A0A0D9QZD2 ENTREZGENE, UniProtKB/TrEMBL