Drd5 (dopamine receptor D5) - Rat Genome Database

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Gene: Drd5 (dopamine receptor D5) Mus musculus
Analyze
Symbol: Drd5
Name: dopamine receptor D5
RGD ID: 10489
MGI Page MGI
Description: Enables dopamine neurotransmitter receptor activity, coupled via Gs. Acts upstream of or within several processes, including learning; long-term synaptic depression; and regulation of blood pressure. Located in brush border membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (dopamine receptor D5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D(1B) dopamine receptor; d(5) dopamine receptor; D5; D5R; dopamine D5 receptor; dopamine receptor 5; Drd-; Drd-5; DRD1; Drd1b; Gpc; Gpcr1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,476,742 - 38,479,868 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl538,476,710 - 38,479,861 (+)EnsemblGRCm39 Ensembl
GRCm38538,319,509 - 38,322,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,319,367 - 38,322,518 (+)EnsemblGRCm38mm10GRCm38
MGSCv37538,710,748 - 38,713,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36538,607,758 - 38,610,559 (+)NCBIMGSCv36mm8
Celera535,773,146 - 35,775,947 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Striatal neurochemical changes in transgenic models of Huntington's disease. Ariano MA, etal., J Neurosci Res. 2002 Jun 15;68(6):716-29.
2. DAT1, DRD4, and DRD5 polymorphisms are not associated with ADHD in Dutch families. Bakker SC, etal., Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):50-2.
3. Increased expression of dopamine receptors on lymphocytes in Parkinson's disease. Barbanti P, etal., Mov Disord. 1999 Sep;14(5):764-71.
4. Attention-deficit hyperactivity disorder and the gene for the dopamine D5 receptor. Barr CL, etal., Mol Psychiatry. 2000 Sep;5(5):548-51.
5. The physiology, signaling, and pharmacology of dopamine receptors. Beaulieu JM and Gainetdinov RR, Pharmacol Rev. 2011 Mar;63(1):182-217. doi: 10.1124/pr.110.002642. Epub 2011 Feb 8.
6. Dopamine receptors - IUPHAR Review 13. Beaulieu JM, etal., Br J Pharmacol. 2015 Jan;172(1):1-23.
7. Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. Hollon TR, etal., J Neurosci. 2002 Dec 15;22(24):10801-10.
8. Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hurle B, etal., Hum Mol Genet 2003 Apr 1;12(7):777-89.
9. Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain. Kumar U and Patel SC, Brain Res. 2007 Feb 2;1131(1):187-96. Epub 2006 Dec 19.
10. Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association of ADHD with DRD4 and DRD5. Kustanovich V, etal., Mol Psychiatry 2004 Jul;9(7):711-7.
11. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. Lemon N and Manahan-Vaughan D, J Neurosci. 2006 Jul 19;26(29):7723-9.
12. The usefulness of the spontaneously hypertensive rat to model attention-deficit/hyperactivity disorder (ADHD) may be explained by the differential expression of dopamine-related genes in the brain. Li Q, etal., Neurochem Int. 2007 May;50(6):848-57. Epub 2007 Mar 1.
13. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
14. MGDs mouse GO annotations MGD data from the GO Consortium
15. MGD IEA MGD IEA
16. A polymorphism in the dopamine receptor DRD5 is associated with blepharospasm. Misbahuddin A, etal., Neurology 2002 Jan 8;58(1):124-6.
17. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
18. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
19. Mouse MP Annotation Import Pipeline RGD automated import pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder. Taurines R, etal., World J Biol Psychiatry. 2011 Sep;12 Suppl 1:104-8.
23. Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Tiberi M, etal., Proc Natl Acad Sci U S A 1991 Sep 1;88(17):7491-5.
Additional References at PubMed
PMID:7609904   PMID:7919654   PMID:8169823   PMID:8177505   PMID:8288218   PMID:8521822   PMID:8748389   PMID:10231569   PMID:10349636   PMID:10843805   PMID:11042159   PMID:11076861  
PMID:11110696   PMID:11217851   PMID:11584926   PMID:11595429   PMID:11597144   PMID:11823893   PMID:11857790   PMID:11935029   PMID:12477932   PMID:12679517   PMID:12768268   PMID:12777963  
PMID:12867509   PMID:13679419   PMID:15100705   PMID:15197646   PMID:15598876   PMID:15668951   PMID:15696326   PMID:16141072   PMID:16141073   PMID:16352863   PMID:16525059   PMID:16602821  
PMID:16962565   PMID:17259440   PMID:17509542   PMID:17936519   PMID:18083900   PMID:18464932   PMID:18784289   PMID:19047479   PMID:19073140   PMID:19204052   PMID:19279248   PMID:20038975  
PMID:20404220   PMID:20478998   PMID:21051739   PMID:21267068   PMID:21709211   PMID:21873635   PMID:21982372   PMID:22219295   PMID:22323706   PMID:22379034   PMID:22764243   PMID:22827965  
PMID:23152498   PMID:23753418   PMID:24155877   PMID:24843151   PMID:24952961   PMID:25131634   PMID:25339698   PMID:25429131   PMID:25560761   PMID:25716648   PMID:26025054   PMID:26053317  
PMID:26174222   PMID:26714288   PMID:26751218   PMID:26763483   PMID:26807952   PMID:28154160   PMID:29167404   PMID:29936463   PMID:30042660   PMID:32035036   PMID:32054879   PMID:33864900  
PMID:34001860   PMID:34074761   PMID:34527710   PMID:34815314   PMID:35399112   PMID:36401517   PMID:39337509  


Genomics

Comparative Map Data
Drd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39538,476,742 - 38,479,868 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl538,476,710 - 38,479,861 (+)EnsemblGRCm39 Ensembl
GRCm38538,319,509 - 38,322,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl538,319,367 - 38,322,518 (+)EnsemblGRCm38mm10GRCm38
MGSCv37538,710,748 - 38,713,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36538,607,758 - 38,610,559 (+)NCBIMGSCv36mm8
Celera535,773,146 - 35,775,947 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.4NCBI
DRD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3849,781,634 - 9,784,009 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl49,781,634 - 9,784,009 (+)EnsemblGRCh38hg38GRCh38
GRCh3749,783,258 - 9,785,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3649,392,701 - 9,394,731 (+)NCBINCBI36Build 36hg18NCBI36
Build 3449,459,871 - 9,461,901NCBI
Celera410,266,117 - 10,268,492 (+)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef49,117,663 - 9,120,038 (+)NCBIHuRef
CHM1_149,781,174 - 9,783,549 (+)NCBICHM1_1
T2T-CHM13v2.049,781,407 - 9,783,782 (+)NCBIT2T-CHM13v2.0
Drd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81476,700,244 - 76,703,344 (-)NCBIGRCr8
mRatBN7.21472,487,950 - 72,491,050 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1472,489,347 - 72,490,774 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1476,931,000 - 76,932,427 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01478,171,890 - 78,173,317 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01474,611,945 - 74,613,372 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01477,220,579 - 77,222,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1477,220,579 - 77,222,006 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01477,202,167 - 77,203,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41477,768,060 - 77,769,487 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11477,770,450 - 77,771,878 (-)NCBI
Celera1471,440,495 - 71,441,922 (-)NCBICelera
Cytogenetic Map14q21NCBI
Drd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555145,450,495 - 5,452,282 (+)NCBIChiLan1.0ChiLan1.0
DRD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2310,026,932 - 10,030,293 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1410,235,569 - 10,237,977 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v044,189,536 - 4,193,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.149,508,711 - 9,511,072 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl49,509,094 - 9,510,527 (+)Ensemblpanpan1.1panPan2
DRD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1369,621,187 - 69,623,522 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl369,621,734 - 69,623,893 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,173,244 - 72,175,212 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0370,378,089 - 70,380,057 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl370,378,633 - 70,380,057 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,652,224 - 69,654,192 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,817,637 - 69,819,605 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0370,198,942 - 70,200,910 (-)NCBIUU_Cfam_GSD_1.0
Drd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528563,158,693 - 63,162,200 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647716,861,773 - 16,863,215 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647716,860,222 - 16,863,505 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl86,180,221 - 6,181,636 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.186,180,221 - 6,182,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.285,694,230 - 5,696,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12740,267,681 - 40,270,061 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2740,268,235 - 40,269,671 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604787,064,155 - 87,066,433 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475521,358,586 - 21,361,410 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Drd5
209 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:345
Count of miRNA genes:260
Interacting mature miRNAs:302
Transcripts:ENSMUST00000041646
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
36049766Ars22_mantibody response to SARS-CoV 22, day 29, IgG3 (mouse)53695734445457342Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
36049767Ars23_mantibody response to SARS-CoV 23, day 29, Total IgG (mouse)53695734445457342Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53811168172111798Mouse
1301845Lxw4_mlupus BXSB x NZW 4 (mouse)Not determined53569446269694594Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
36049774Ars16_mantibody response to SARS-CoV 16, day 7, Total IgG (mouse)53695734445457342Mouse
36049775Ars17_mantibody response to SARS-CoV 17, day 15, IgG2a+IgG2c (mouse)53695734445457342Mouse
36049772Ars20_mantibody response to SARS-CoV 20, day 15, Total IgG (mouse)53695734445457342Mouse
36049773Ars21_mantibody response to SARS-CoV 21, day 29, IgG2a+IgG2c (mouse)53695734445457342Mouse
36049770Ars14_mantibody response to SARS-CoV 14, day 7, IgG3 (mouse)53695734445457342Mouse
36049771Ars15_mantibody response to SARS-CoV 15, day 7, IgM (mouse)53695734445457342Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
36049768Ars24_mantibody response to SARS-CoV 24, 4 days post-rechallenge, IgG3 (mouse)53695734445457342Mouse
36049769Ars13_mantibody response to SARS-CoV 13, day 7, IgG2a+IgG2c (mouse)53695734445457342Mouse
36049776Ars18_mantibody response to SARS-CoV 18, day 15, IgG3 (mouse)53695734445457342Mouse
36049777Ars19_mantibody response to SARS-CoV 19, day 15, IgM (mouse)53695734445457342Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
1301170Lith13_mlithogenic gene 13 (mouse)Not determined53649448670494598Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
1300926Hpi2_mhepatic PMN infiltration 2 (mouse)Not determined53758148864806579Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
4141647Hrvhf1_mheart rate variability, high frequency 1 (mouse)Not determined3643342370433423Mouse
11049561Lmr24e_mleishmaniasis resistance 24e (mouse)53569446269694594Mouse
13464252Ahl10_mage related hearing loss, early onset 10 (mouse)53585456869854714Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
1301223Hdlq7_mHDL QTL 7 (mouse)Not determined53585456869854714Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53811168172111798Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
13464246Ahl11_mage related hearing loss, early onset 11 (mouse)53764377771643896Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
11049558Lmr24b_mleishmaniasis resistance 24b (mouse)53569446269694594Mouse
35673310Ari4_mantibody response to influenza 4, day 15-45, IgG2b (mouse)53695734445457342Mouse
11049559Lmr24c_mleishmaniasis resistance 24c (mouse)53569446269694594Mouse

Markers in Region
Drd5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,320,312 - 38,320,412UniSTSGRCm38
MGSCv37538,711,551 - 38,711,651UniSTSGRCm37
Celera535,773,949 - 35,774,049UniSTS
Cytogenetic Map5B3UniSTS
cM Map523.0UniSTS
D14Wox23  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,321,064 - 38,321,220UniSTSGRCm38
MGSCv37538,712,303 - 38,712,459UniSTSGRCm37
Celera535,774,701 - 35,774,857UniSTS
Cytogenetic Map5B3UniSTS
cM Map523.0UniSTS
D14Mco14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,321,049 - 38,321,223UniSTSGRCm38
MGSCv37538,712,288 - 38,712,462UniSTSGRCm37
Celera535,774,686 - 35,774,860UniSTS
Cytogenetic Map5B3UniSTS
cM Map523.0UniSTS
D14Arb11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,320,972 - 38,321,223UniSTSGRCm38
MGSCv37538,712,211 - 38,712,462UniSTSGRCm37
Celera535,774,609 - 35,774,860UniSTS
Cytogenetic Map5B3UniSTS
cM Map523.0UniSTS
Drd5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,320,840 - 38,321,023UniSTSGRCm38
MGSCv37538,712,079 - 38,712,262UniSTSGRCm37
Celera535,774,477 - 35,774,660UniSTS
Cytogenetic Map5B3UniSTS
cM Map523.0UniSTS
Drd5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38538,320,383 - 38,320,452UniSTSGRCm38
MGSCv37538,711,622 - 38,711,691UniSTSGRCm37
Celera535,774,020 - 35,774,089UniSTS
Cytogenetic Map5B3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000041646   ⟹   ENSMUSP00000039691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl538,476,710 - 38,479,861 (+)Ensembl
GRCm38.p6 Ensembl538,319,367 - 38,322,518 (+)Ensembl
RefSeq Acc Id: NM_013503   ⟹   NP_038531
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39538,476,742 - 38,479,868 (+)NCBI
GRCm38538,319,509 - 38,322,523 (+)NCBI
MGSCv37538,710,748 - 38,713,549 (+)RGD
Celera535,773,146 - 35,775,947 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_038531   ⟸   NM_013503
- UniProtKB: Q61439 (UniProtKB/Swiss-Prot),   Q80UB7 (UniProtKB/Swiss-Prot),   Q8BLD9 (UniProtKB/Swiss-Prot),   B2RQS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000039691   ⟸   ENSMUST00000041646
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BLD9-F1-model_v2 AlphaFold Q8BLD9 1-478 view protein structure

Promoters
RGD ID:6837389
Promoter ID:MM_KWN:42110
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:NM_013503
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36538,710,786 - 38,711,286 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:94927 AgrOrtholog
Ensembl Genes ENSMUSG00000039358 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000041646 ENTREZGENE
  ENSMUST00000041646.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Dopamine_D5_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dopamine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13492 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:94927 ENTREZGENE
NCBI Gene 13492 ENTREZGENE
PANTHER ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  D(1B) DOPAMINE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB DRD5 RGD
PhenoGen Drd5 PhenoGen
PRINTS DOPAMINED1BR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DOPAMINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RQS5 ENTREZGENE, UniProtKB/TrEMBL
  DRD5_MOUSE UniProtKB/Swiss-Prot
  Q61439 ENTREZGENE
  Q80UB7 ENTREZGENE
  Q8BLD9 ENTREZGENE
UniProt Secondary Q61439 UniProtKB/Swiss-Prot
  Q80UB7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Drd5  dopamine receptor D5  Drd5  dopamine receptor 5  Symbol and/or name change 5135510 APPROVED