Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Drd5 (dopamine receptor D5) Mus musculus
Symbol: Drd5
Name: dopamine receptor D5
RGD ID: 10489
Description: Exhibits dopamine neurotransmitter receptor activity, coupled via Gs. Involved in several processes, including learning; long-term synaptic depression; and regulation of blood pressure. Localizes to brush border membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (dopamine receptor D5); PARTICIPATES IN dopamine signaling pathway; dopamine signaling pathway via D1 family of receptors; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 1,2-dimethylhydrazine; 3,4-methylenedioxymethamphetamine; arsenite(3-).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D(1B) dopamine receptor; d(5) dopamine receptor; D5; D5R; dopamine D5 receptor; dopamine receptor 5; Drd-; Drd-5; DRD1; Drd1b; Gpc; Gpcr1
Homo sapiens (human) : DRD5 (dopamine receptor D5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Drd5 (dopamine receptor D5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drd5 (dopamine receptor D5)
Pan paniscus (bonobo/pygmy chimpanzee) : DRD5 (dopamine receptor D5)
Canis lupus familiaris (dog) : DRD5 (dopamine receptor D5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drd5 (dopamine receptor D5)
Sus scrofa (pig) : DRD5 (dopamine receptor D5)
Chlorocebus sabaeus (African green monkey) : DRD5 (dopamine receptor D5)
Heterocephalus glaber (naked mole-rat) : Drd5 (dopamine receptor D5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl538,319,367 - 38,322,518 (+)EnsemblGRCm38mm10GRCm38
GRCm38538,319,509 - 38,322,523 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37538,710,748 - 38,713,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36538,607,758 - 38,610,559 (+)NCBImm8
Celera535,773,146 - 35,775,947 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map520.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Drd5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10489
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.