HTT (huntingtin) - Rat Genome Database

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Gene: HTT (huntingtin) Homo sapiens
Analyze
Symbol: HTT
Name: huntingtin
RGD ID: 68472
HGNC Page HGNC
Description: Enables several functions, including cytoskeletal protein binding activity; dynein intermediate chain binding activity; and p53 binding activity. Involved in several processes, including positive regulation of autophagy; protein destabilization; and regulation of signal transduction. Acts upstream of or within regulation of phosphoprotein phosphatase activity. Located in several cellular components, including autophagosome; centriole; and cytoplasmic vesicle. Part of protein-containing complex. Is active in postsynaptic cytosol and presynaptic cytosol. Implicated in Huntington's disease and Parkinson's disease. Biomarker of Huntington's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HD; huntington disease gene homolog; huntington disease protein; IT15; LOMARS
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Is Marker For: Strains:   SD-Tg(Htt*)  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl43,041,363 - 3,243,957 (+)EnsemblGRCh38hg38GRCh38
GRCh3843,074,681 - 3,243,960 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3743,076,408 - 3,245,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,046,206 - 3,215,485 (+)NCBINCBI36hg18NCBI36
Build 3443,113,411 - 3,282,656NCBI
Celera42,987,658 - 3,157,211 (+)NCBI
Cytogenetic Map4p16.3NCBI
HuRef43,014,819 - 3,184,168 (+)NCBIHuRef
CHM1_143,074,471 - 3,243,442 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (ISO)
anterior/posterior pattern specification  (ISO)
apoptotic process  (IEA)
associative learning  (ISO)
axo-dendritic transport  (ISO)
brain development  (ISO)
cell aging  (ISO)
central nervous system development  (ISO)
citrulline metabolic process  (ISO)
determination of adult lifespan  (ISO)
dopamine receptor signaling pathway  (ISO)
endoplasmic reticulum organization  (ISO)
endoplasmic reticulum to Golgi vesicle-mediated transport  (ISO)
endosomal transport  (ISO)
establishment of mitotic spindle orientation  (IMP)
gastrulation  (ISO)
Golgi organization  (IMP)
grooming behavior  (ISO)
hormone metabolic process  (ISO)
insulin secretion  (ISO)
iron ion homeostasis  (ISO)
lactate biosynthetic process from pyruvate  (ISO)
learning  (ISO)
learning or memory  (ISO)
locomotory behavior  (ISO)
microtubule-based transport  (IBA)
mitochondrial transport  (ISO)
mitochondrion organization  (ISO)
mRNA transport  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cysteine-type endopeptidase activity  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IMP)
neural plate formation  (ISO)
neurogenesis  (ISO)
neuron development  (ISO)
olfactory lobe development  (ISO)
paraxial mesoderm formation  (ISO)
peptide hormone secretion  (ISO)
positive regulation of aggrephagy  (IMP)
positive regulation of apoptotic process  (IDA)
positive regulation of autophagy of mitochondrion  (IMP)
positive regulation of cilium assembly  (IMP)
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity  (IDA)
positive regulation of lipophagy  (IMP)
positive regulation of motile cilium assembly  (ISO)
positive regulation of non-motile cilium assembly  (ISO)
postsynapse to nucleus signaling pathway  (ISO)
protein destabilization  (IMP)
protein localization to centrosome  (ISO)
protein localization to nucleus  (ISO)
quinolinate biosynthetic process  (ISO)
regulation of CAMKK-AMPK signaling cascade  (IMP)
regulation of cAMP-dependent protein kinase activity  (IMP)
regulation of gene expression  (ISO)
regulation of intracellular mRNA localization  (ISO)
regulation of neuron apoptotic process  (ISO)
regulation of phosphoprotein phosphatase activity  (IMP)
regulation of protein localization to nucleus  (ISO)
regulation of synaptic plasticity  (ISO)
response to calcium ion  (ISO)
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  (IMP)
social behavior  (ISO)
spermatogenesis  (ISO)
striatum development  (ISO)
urea cycle  (ISO)
vesicle transport along microtubule  (IMP,ISO)
visual learning  (ISO)
vocal learning  (IMP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal cerebral white matter morphology  (IAGP)
Abnormal circulating cholesterol concentration  (IAGP)
Abnormal involuntary eye movements  (IAGP)
Abnormal libido  (IAGP)
Abnormal pyramidal sign  (IAGP)
Abnormality of eye movement  (IAGP)
Abnormality of the sense of smell  (IAGP)
Absent speech  (IAGP)
Aggressive behavior  (IAGP)
Agitation  (IAGP)
Alcoholism  (IAGP)
Ankle clonus  (IAGP)
Anxiety  (IAGP)
Apathy  (IAGP)
Autosomal dominant inheritance  (IAGP)
Autosomal recessive inheritance  (IAGP)
Babinski sign  (IAGP)
Bradykinesia  (IAGP)
Bradyphrenia  (IAGP)
Broad-based gait  (IAGP)
Bruxism  (IAGP)
Caudate atrophy  (IAGP)
Cerebellar atrophy  (IAGP)
Cerebellar vermis atrophy  (IAGP)
Cerebral atrophy  (IAGP)
Choking episodes  (IAGP)
Chorea  (IAGP)
Clonus  (IAGP)
Clumsiness  (IAGP)
Decreased body mass index  (IAGP)
Degeneration of the striatum  (IAGP)
Delusions  (IAGP)
Dementia  (IAGP)
Depression  (IAGP)
Developmental regression  (IAGP)
Difficulty walking  (IAGP)
Disinhibition  (IAGP)
Dysphagia  (IAGP)
Dystonia  (IAGP)
Excessive daytime somnolence  (IAGP)
Feeding difficulties  (IAGP)
Gait ataxia  (IAGP)
Gait imbalance  (IAGP)
Generalized muscle weakness  (IAGP)
Gliosis  (IAGP)
Global developmental delay  (IAGP)
Hallucinations  (IAGP)
Hostility  (IAGP)
Hyperactivity  (IAGP)
Hyperreflexia  (IAGP)
Hypokinesia  (IAGP)
Impaired visuospatial constructive cognition  (IAGP)
Inability to walk  (IAGP)
Insomnia  (IAGP)
Intellectual disability, severe  (IAGP)
Irritability  (IAGP)
Kyphosis  (IAGP)
Memory impairment  (IAGP)
Mental deterioration  (IAGP)
Muscular hypotonia of the trunk  (IAGP)
Mutism  (IAGP)
Myoclonus  (IAGP)
Myopia  (IAGP)
Neuronal loss in basal ganglia  (IAGP)
Neuronal loss in central nervous system  (IAGP)
Obsessive-compulsive behavior  (IAGP)
Oral motor hypotonia  (IAGP)
Oral-pharyngeal dysphagia  (IAGP)
Personality changes  (IAGP)
Polyphagia  (IAGP)
Poor fine motor coordination  (IAGP)
Progressive cerebellar ataxia  (IAGP)
Rigidity  (IAGP)
Scoliosis  (IAGP)
Seizure  (IAGP)
Short foot  (IAGP)
Small hand  (IAGP)
Spasticity  (IAGP)
Speech articulation difficulties  (IAGP)
Staring gaze  (IAGP)
Suicidal ideation  (IAGP)
Tremor  (IAGP)
Unsteady gait  (IAGP)
Ventriculomegaly  (IAGP)
Weight loss  (IAGP)
References

Additional References at PubMed
PMID:1302016   PMID:7477378   PMID:7568002   PMID:7647777   PMID:7748555   PMID:7759106   PMID:7903579   PMID:7951324   PMID:8162057   PMID:8197474   PMID:8458085   PMID:8612237  
PMID:8696339   PMID:8702625   PMID:8889548   PMID:9079622   PMID:9140394   PMID:9147654   PMID:9152833   PMID:9285789   PMID:9454836   PMID:9466992   PMID:9535906   PMID:9599014  
PMID:9668110   PMID:9700202   PMID:9778247   PMID:9798945   PMID:9809064   PMID:10332029   PMID:10353249   PMID:10410676   PMID:10434301   PMID:10441327   PMID:10770929   PMID:10801775  
PMID:10823891   PMID:10958656   PMID:10974549   PMID:11008591   PMID:11013077   PMID:11035034   PMID:11063258   PMID:11092755   PMID:11105061   PMID:11121205   PMID:11137014   PMID:11149616  
PMID:11172033   PMID:11264541   PMID:11319238   PMID:11379408   PMID:11432963   PMID:11442349   PMID:11461154   PMID:11468270   PMID:11487199   PMID:11595021   PMID:11607033   PMID:11642542  
PMID:11738012   PMID:11739372   PMID:11745989   PMID:11788820   PMID:11792860   PMID:11807410   PMID:11839795   PMID:11854752   PMID:11870213   PMID:11906693   PMID:11939977   PMID:11971872  
PMID:11973620   PMID:11988536   PMID:12062094   PMID:12135980   PMID:12191472   PMID:12204002   PMID:12354289   PMID:12354780   PMID:12379151   PMID:12393306   PMID:12393793   PMID:12417652  
PMID:12427879   PMID:12456676   PMID:12466534   PMID:12477932   PMID:12548366   PMID:12555240   PMID:12569151   PMID:12604778   PMID:12657678   PMID:12682342   PMID:12783847   PMID:12784292  
PMID:12799135   PMID:12807877   PMID:12810713   PMID:12824708   PMID:12873381   PMID:12881483   PMID:12881722   PMID:12952868   PMID:12956863   PMID:14527999   PMID:14570710   PMID:14570907  
PMID:14572927   PMID:14617779   PMID:14657499   PMID:14713958   PMID:14714490   PMID:14743370   PMID:14978262   PMID:14985437   PMID:15032971   PMID:15064418   PMID:15140195   PMID:15140196  
PMID:15163634   PMID:15225551   PMID:15240759   PMID:15261377   PMID:15273431   PMID:15312898   PMID:15316797   PMID:15338298   PMID:15340079   PMID:15351733   PMID:15359012   PMID:15371500  
PMID:15383276   PMID:15468075   PMID:15496672   PMID:15603740   PMID:15610167   PMID:15654337   PMID:15689617   PMID:15716522   PMID:15717026   PMID:15809304   PMID:15815621   PMID:15832309  
PMID:15837803   PMID:15843398   PMID:15890517   PMID:15911879   PMID:15916486   PMID:15936278   PMID:15951191   PMID:15994095   PMID:15996546   PMID:16006135   PMID:16085648   PMID:16091361  
PMID:16115810   PMID:16115812   PMID:16162412   PMID:16169070   PMID:16183657   PMID:16192271   PMID:16204350   PMID:16207717   PMID:16278683   PMID:16286508   PMID:16324236   PMID:16365166  
PMID:16391387   PMID:16417581   PMID:16452635   PMID:16456924   PMID:16473015   PMID:16476778   PMID:16492755   PMID:16522639   PMID:16595690   PMID:16606912   PMID:16729030   PMID:16777606  
PMID:16782707   PMID:16835690   PMID:16968735   PMID:16973623   PMID:17012230   PMID:17098699   PMID:17115386   PMID:17124493   PMID:17126554   PMID:17135277   PMID:17141218   PMID:17151278  
PMID:17161366   PMID:17189290   PMID:17201528   PMID:17208201   PMID:17240517   PMID:17276991   PMID:17299753   PMID:17361007   PMID:17403029   PMID:17409200   PMID:17433700   PMID:17500595  
PMID:17519223   PMID:17548833   PMID:17603015   PMID:17610899   PMID:17611284   PMID:17660463   PMID:17687393   PMID:17704510   PMID:17708681   PMID:17902043   PMID:17941857   PMID:17947297  
PMID:17948889   PMID:17952586   PMID:17975550   PMID:17989880   PMID:18006506   PMID:18029348   PMID:18029446   PMID:18063376   PMID:18065495   PMID:18068007   PMID:18078716   PMID:18091069  
PMID:18157708   PMID:18166084   PMID:18192679   PMID:18255062   PMID:18267960   PMID:18337408   PMID:18380890   PMID:18400894   PMID:18445618   PMID:18504298   PMID:18558632   PMID:18573880  
PMID:18586675   PMID:18615096   PMID:18632688   PMID:18640989   PMID:18649400   PMID:18651325   PMID:18669659   PMID:18718937   PMID:18772195   PMID:18831068   PMID:18922795   PMID:18981372  
PMID:18986984   PMID:18992820   PMID:19018245   PMID:19026253   PMID:19027857   PMID:19039036   PMID:19059613   PMID:19115052   PMID:19130884   PMID:19133136   PMID:19196932   PMID:19204007  
PMID:19240033   PMID:19240112   PMID:19249009   PMID:19250382   PMID:19266143   PMID:19268537   PMID:19270310   PMID:19270701   PMID:19289118   PMID:19361448   PMID:19386911   PMID:19451134  
PMID:19487684   PMID:19488402   PMID:19492089   PMID:19498170   PMID:19525941   PMID:19566678   PMID:19628478   PMID:19656852   PMID:19661690   PMID:19667213   PMID:19710014   PMID:19726651  
PMID:19748341   PMID:19752198   PMID:19776381   PMID:19915590   PMID:19916101   PMID:19933700   PMID:19969308   PMID:20016493   PMID:20016831   PMID:20018729   PMID:20026071   PMID:20026656  
PMID:20056037   PMID:20064390   PMID:20097678   PMID:20126661   PMID:20140226   PMID:20145253   PMID:20154145   PMID:20204693   PMID:20232225   PMID:20301334   PMID:20301482   PMID:20360314  
PMID:20379614   PMID:20417604   PMID:20444706   PMID:20494921   PMID:20515468   PMID:20531388   PMID:20696378   PMID:20708032   PMID:20710011   PMID:20800603   PMID:20858895   PMID:20864123  
PMID:20864533   PMID:20875859   PMID:21044956   PMID:21087194   PMID:21147489   PMID:21169558   PMID:21177255   PMID:21192926   PMID:21209075   PMID:21245084   PMID:21248742   PMID:21257639  
PMID:21280221   PMID:21310951   PMID:21315254   PMID:21320997   PMID:21322024   PMID:21336284   PMID:21364626   PMID:21454471   PMID:21458571   PMID:21465263   PMID:21482444   PMID:21501628  
PMID:21509658   PMID:21515588   PMID:21518730   PMID:21519949   PMID:21540131   PMID:21562226   PMID:21566141   PMID:21685499   PMID:21768291   PMID:21873635   PMID:21875723   PMID:21887328  
PMID:21889504   PMID:21889981   PMID:21896647   PMID:21909508   PMID:21954231   PMID:21968397   PMID:21971427   PMID:21983719   PMID:21984825   PMID:21985783   PMID:21997870   PMID:22011578  
PMID:22048026   PMID:22072510   PMID:22100810   PMID:22101303   PMID:22103299   PMID:22110140   PMID:22119730   PMID:22123826   PMID:22162197   PMID:22178474   PMID:22178478   PMID:22179316  
PMID:22219281   PMID:22234237   PMID:22235343   PMID:22306231   PMID:22306738   PMID:22337954   PMID:22352297   PMID:22359536   PMID:22375012   PMID:22399227   PMID:22409360   PMID:22422149  
PMID:22433867   PMID:22445760   PMID:22511757   PMID:22536159   PMID:22556411   PMID:22573320   PMID:22580459   PMID:22623107   PMID:22642889   PMID:22735540   PMID:22801429   PMID:22815947  
PMID:22835334   PMID:22854022   PMID:22863883   PMID:22891683   PMID:22906125   PMID:22917585   PMID:22974559   PMID:22984513   PMID:23012356   PMID:23051704   PMID:23071649   PMID:23115180  
PMID:23160193   PMID:23190281   PMID:23225006   PMID:23272104   PMID:23275563   PMID:23293686   PMID:23297360   PMID:23300147   PMID:23303669   PMID:23305455   PMID:23315009   PMID:23319588  
PMID:23339311   PMID:23370273   PMID:23383273   PMID:23443539   PMID:23575829   PMID:23583659   PMID:23624566   PMID:23652004   PMID:23768628   PMID:23774650   PMID:23853712   PMID:23898200  
PMID:23908352   PMID:23966247   PMID:23980182   PMID:24054538   PMID:24081492   PMID:24086178   PMID:24196953   PMID:24199621   PMID:24217578   PMID:24277524   PMID:24291262   PMID:24314096  
PMID:24377263   PMID:24405192   PMID:24407293   PMID:24412307   PMID:24412394   PMID:24415136   PMID:24459107   PMID:24459296   PMID:24471773   PMID:24505464   PMID:24584051   PMID:24651384  
PMID:24705354   PMID:24722188   PMID:24747660   PMID:24769000   PMID:24784230   PMID:24798518   PMID:24819723   PMID:24828240   PMID:24836077   PMID:24865853   PMID:24882209   PMID:24951540  
PMID:24998512   PMID:25017010   PMID:25041730   PMID:25092318   PMID:25131594   PMID:25143394   PMID:25205111   PMID:25271967   PMID:25311206   PMID:25351248   PMID:25380050   PMID:25380582  
PMID:25398943   PMID:25416977   PMID:25446099   PMID:25452431   PMID:25464109   PMID:25464275   PMID:25505242   PMID:25540325   PMID:25558820   PMID:25686248   PMID:25726852   PMID:25736541  
PMID:25752541   PMID:25773959   PMID:25848931   PMID:25849918   PMID:25866151   PMID:25938884   PMID:25959826   PMID:25995452   PMID:26001312   PMID:26002199   PMID:26010866   PMID:26020223  
PMID:26025364   PMID:26106822   PMID:26111612   PMID:26141599   PMID:26165689   PMID:26186194   PMID:26198635   PMID:26218986   PMID:26264729   PMID:26293574   PMID:26333261   PMID:26369532  
PMID:26436900   PMID:26450664   PMID:26485645   PMID:26496077   PMID:26496610   PMID:26529236   PMID:26540094   PMID:26586297   PMID:26652744   PMID:26673834   PMID:26808260   PMID:26850319  
PMID:26863614   PMID:26953320   PMID:26959244   PMID:26980106   PMID:27002149   PMID:27082842   PMID:27206983   PMID:27220690   PMID:27329733   PMID:27335115   PMID:27377031   PMID:27382061  
PMID:27402890   PMID:27466181   PMID:27483361   PMID:27561680   PMID:27570076   PMID:27678206   PMID:27721240   PMID:27721444   PMID:27740685   PMID:27840155   PMID:27870408   PMID:27988204  
PMID:28017939   PMID:28096892   PMID:28111121   PMID:28153533   PMID:28165127   PMID:28282438   PMID:28286179   PMID:28298427   PMID:28339398   PMID:28368337   PMID:28369732   PMID:28384479  
PMID:28387881   PMID:28436437   PMID:28445460   PMID:28453524   PMID:28465506   PMID:28494017   PMID:28499347   PMID:28514442   PMID:28539049   PMID:28550168   PMID:28550267   PMID:28570578  
PMID:28611215   PMID:28617590   PMID:28621522   PMID:28638078   PMID:28653853   PMID:28674979   PMID:28698602   PMID:28753941   PMID:28864412   PMID:28869595   PMID:28900094   PMID:28920551  
PMID:28937758   PMID:28971465   PMID:29093475   PMID:29151587   PMID:29162692   PMID:29171910   PMID:29212816   PMID:29225330   PMID:29282287   PMID:29324753   PMID:29358329   PMID:29362455  
PMID:29378824   PMID:29394115   PMID:29401586   PMID:29430620   PMID:29460266   PMID:29466333   PMID:29507755   PMID:29510748   PMID:29526547   PMID:29601786   PMID:29619771   PMID:29627459  
PMID:29630769   PMID:29668904   PMID:29685790   PMID:29713895   PMID:29727175   PMID:29743609   PMID:29789657   PMID:29802276   PMID:29891550   PMID:29912367   PMID:29932473   PMID:29956026  
PMID:30069866   PMID:30072438   PMID:30103339   PMID:30209243   PMID:30279700   PMID:30315108   PMID:30332437   PMID:30358836   PMID:30389496   PMID:30423259   PMID:30452683   PMID:30583877  
PMID:30624705   PMID:30768638   PMID:30788585   PMID:30802639   PMID:30808748   PMID:30886048   PMID:30994454   PMID:31091453   PMID:31240132   PMID:31282030   PMID:31296921   PMID:31300691  
PMID:31346086   PMID:31359503   PMID:31361762   PMID:31428776   PMID:31444920   PMID:31450785   PMID:31466833   PMID:31638189   PMID:31677786   PMID:31681295   PMID:31757420   PMID:31814404  
PMID:31828084   PMID:31844074   PMID:31928144   PMID:32067426   PMID:32242231   PMID:32407769   PMID:32422281   PMID:32439599   PMID:32451438   PMID:32560122   PMID:32592593   PMID:32598938  
PMID:32652810   PMID:32668197   PMID:32694731   PMID:32696070   PMID:32735619   PMID:32757223   PMID:32814053   PMID:32820193   PMID:32821928   PMID:32838362   PMID:32913184   PMID:33001583  
PMID:33023443   PMID:33057179   PMID:33086646   PMID:33130095   PMID:33159825   PMID:33219289   PMID:33228555   PMID:33233776   PMID:33242422   PMID:33247537   PMID:33256402   PMID:33310753  
PMID:33335120   PMID:33468657   PMID:33576152   PMID:33674575   PMID:33692166   PMID:34079125   PMID:34201610   PMID:34239038  


Genomics

Comparative Map Data
HTT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl43,041,363 - 3,243,957 (+)EnsemblGRCh38hg38GRCh38
GRCh3843,074,681 - 3,243,960 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3743,076,408 - 3,245,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,046,206 - 3,215,485 (+)NCBINCBI36hg18NCBI36
Build 3443,113,411 - 3,282,656NCBI
Celera42,987,658 - 3,157,211 (+)NCBI
Cytogenetic Map4p16.3NCBI
HuRef43,014,819 - 3,184,168 (+)NCBIHuRef
CHM1_143,074,471 - 3,243,442 (+)NCBICHM1_1
Htt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39534,919,084 - 35,069,878 (+)NCBIGRCm39mm39
GRCm39 Ensembl534,919,084 - 35,069,878 (+)Ensembl
GRCm38534,761,721 - 34,912,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,761,740 - 34,912,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,104,389 - 35,252,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv36535,078,597 - 35,226,253 (+)NCBImm8
Celera532,235,862 - 32,383,257 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.92NCBI
Htt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21475,845,836 - 75,996,094 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1475,845,836 - 75,995,070 (-)Ensembl
Rnor_6.01481,105,139 - 81,254,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1481,105,139 - 81,254,637 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,793,632 - 81,942,093 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,490,322 - 81,636,856 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11481,492,926 - 81,639,072 (-)NCBI
Celera1474,771,910 - 74,919,669 (-)NCBICelera
Cytogenetic Map14q21NCBI
Htt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555141,906,502 - 2,038,889 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555141,906,189 - 2,042,357 (+)NCBIChiLan1.0ChiLan1.0
HTT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.143,116,810 - 3,287,644 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl43,128,718 - 3,283,730 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v043,215,081 - 3,388,587 (+)NCBIMhudiblu_PPA_v0panPan3
HTT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1361,076,934 - 61,221,462 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl361,079,904 - 61,330,290 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,660,661 - 63,805,148 (-)NCBI
ROS_Cfam_1.0361,552,532 - 61,697,091 (-)NCBI
UMICH_Zoey_3.1361,044,140 - 61,188,581 (-)NCBI
UNSW_CanFamBas_1.0361,248,468 - 61,393,186 (-)NCBI
UU_Cfam_GSD_1.0361,608,204 - 61,752,888 (-)NCBI
LOC101966195
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,741,409 - 66,966,567 (-)NCBI
SpeTri2.0NW_00493647720,443,101 - 20,577,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl81,809,785 - 1,934,024 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,809,768 - 1,934,002 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.281,461,795 - 1,586,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8pNCBI
HTT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12745,493,467 - 45,657,690 (-)NCBI
ChlSab1.1 Ensembl2745,497,352 - 45,657,621 (-)Ensembl
Vero_WHO_p1.0NW_0236660511,852,227 - 1,977,171 (-)NCBI
Htt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475524,602,955 - 24,729,584 (-)NCBI

Position Markers
D4S1337  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,241,936 - 3,242,091UniSTSGRCh37
Build 3643,211,734 - 3,211,889RGDNCBI36
Celera43,153,457 - 3,153,612RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,180,414 - 3,180,569UniSTS
TNG Radiation Hybrid Map41731.0UniSTS
G42605  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,242,020 - 3,242,202UniSTSGRCh37
Build 3643,211,818 - 3,212,000RGDNCBI36
Celera43,153,541 - 3,153,723RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,180,498 - 3,180,680UniSTS
GDB:197987  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,574 - 3,076,823UniSTSGRCh37
Build 3643,046,372 - 3,046,621RGDNCBI36
Celera42,987,824 - 2,988,071RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,014,985 - 3,015,231UniSTS
GDB:316174  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,650 - 3,076,713UniSTSGRCh37
Build 3643,046,448 - 3,046,511RGDNCBI36
Cytogenetic Map4p16.3UniSTS
HuRef43,015,058 - 3,015,121UniSTS
GDB:363587  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,230,362 - 3,230,473UniSTSGRCh37
Build 3643,200,160 - 3,200,271RGDNCBI36
Celera43,141,883 - 3,141,994RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,168,840 - 3,168,951UniSTS
G33683  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,215,296 - 3,215,467UniSTSGRCh37
Build 3643,185,094 - 3,185,265RGDNCBI36
Celera43,126,851 - 3,127,022RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,153,808 - 3,153,979UniSTS
PMC166399P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,556 - 3,076,743UniSTSGRCh37
Build 3643,046,354 - 3,046,541RGDNCBI36
Celera42,987,806 - 2,987,991RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,014,967 - 3,015,151UniSTS
PMC166399P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,581 - 3,076,714UniSTSGRCh37
Build 3643,046,379 - 3,046,512RGDNCBI36
Celera42,987,831 - 2,987,962RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,014,992 - 3,015,122UniSTS
PMC20760P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,432 - 3,076,716UniSTSGRCh37
Build 3643,046,230 - 3,046,514RGDNCBI36
Celera42,987,682 - 2,987,964RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,014,843 - 3,015,124UniSTS
RH66772  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,090,855 - 3,090,975UniSTSGRCh37
Build 3643,060,653 - 3,060,773RGDNCBI36
Celera43,002,102 - 3,002,222RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,029,255 - 3,029,375UniSTS
GeneMap99-GB4 RH Map429.92UniSTS
NCBI RH Map455.5UniSTS
SHGC-51023  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,234,139 - 3,234,268UniSTSGRCh37
Build 3643,203,937 - 3,204,066RGDNCBI36
Celera43,145,660 - 3,145,789RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,172,617 - 3,172,746UniSTS
TNG Radiation Hybrid Map41731.0UniSTS
HD__6704  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,241,645 - 3,242,420UniSTSGRCh37
Build 3643,211,443 - 3,212,218RGDNCBI36
Celera43,153,166 - 3,153,941RGD
HuRef43,180,123 - 3,180,898UniSTS
D4S2663  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,215,320 - 3,215,475UniSTSGRCh37
Build 3643,185,118 - 3,185,273RGDNCBI36
Celera43,126,875 - 3,127,030RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,153,832 - 3,153,987UniSTS
TNG Radiation Hybrid Map41666.0UniSTS
Stanford-G3 RH Map4217.0UniSTS
Whitehead-RH Map420.0UniSTS
NCBI RH Map456.7UniSTS
SHGC-59533  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,240,190 - 3,240,364UniSTSGRCh37
Build 3643,209,988 - 3,210,162RGDNCBI36
Celera43,151,711 - 3,151,885RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,178,668 - 3,178,842UniSTS
GeneMap99-GB4 RH Map428.11UniSTS
NCBI RH Map465.7UniSTS
D4S3290  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,245,454 - 3,245,592UniSTSGRCh37
Build 3643,215,252 - 3,215,390RGDNCBI36
Celera43,156,978 - 3,157,116RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,183,935 - 3,184,073UniSTS
SHGC-50176  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,245,454 - 3,245,614UniSTSGRCh37
Build 3643,215,252 - 3,215,412RGDNCBI36
Celera43,156,978 - 3,157,138RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,183,935 - 3,184,095UniSTS
TNG Radiation Hybrid Map41746.0UniSTS
SHGC-67369  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,242,124 - 3,242,261UniSTSGRCh37
Build 3643,211,922 - 3,212,059RGDNCBI36
Celera43,153,645 - 3,153,782RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,180,602 - 3,180,739UniSTS
GeneMap99-GB4 RH Map429.92UniSTS
NCBI RH Map455.5UniSTS
WI-20376  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,245,338 - 3,245,588UniSTSGRCh37
Build 3643,215,136 - 3,215,386RGDNCBI36
Celera43,156,862 - 3,157,112RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,183,819 - 3,184,069UniSTS
GeneMap99-GB4 RH Map429.92UniSTS
Whitehead-RH Map420.0UniSTS
NCBI RH Map468.1UniSTS
SHGC-67859  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,245,191 - 3,245,380UniSTSGRCh37
Build 3643,214,989 - 3,215,178RGDNCBI36
Celera43,156,715 - 3,156,904RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,183,672 - 3,183,861UniSTS
GeneMap99-GB4 RH Map428.11UniSTS
NCBI RH Map465.7UniSTS
D4S281  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,201,971 - 3,202,247UniSTSGRCh37
Build 3643,171,769 - 3,172,045RGDNCBI36
Celera43,113,526 - 3,113,802RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,140,483 - 3,140,759UniSTS
TNG Radiation Hybrid Map41671.0UniSTS
SHGC-30823  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,205,038 - 3,205,162UniSTSGRCh37
Build 3643,174,836 - 3,174,960RGDNCBI36
Celera43,116,593 - 3,116,717RGD
Cytogenetic Map4p16.3UniSTS
HuRef43,143,550 - 3,143,674UniSTS
TNG Radiation Hybrid Map41676.0UniSTS
GeneMap99-GB4 RH Map428.11UniSTS
Whitehead-RH Map418.3UniSTS
NCBI RH Map465.7UniSTS
GeneMap99-G3 RH Map4201.0UniSTS
GDB:249651  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4p16.3UniSTS
GDB:363582  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,230,366 - 3,231,649UniSTSGRCh37
Celera43,141,887 - 3,143,170UniSTS
Cytogenetic Map4p16.3UniSTS
HuRef43,168,844 - 3,170,127UniSTS
GDB:372940  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3743,076,237 - 3,076,575UniSTSGRCh37
Celera42,987,487 - 2,987,825UniSTS
Cytogenetic Map4p16.3UniSTS
HuRef43,014,648 - 3,014,986UniSTS


Related Rat Strains
The following Strains have been annotated to HTT

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4657
Count of miRNA genes:1261
Interacting mature miRNAs:1650
Transcripts:ENST00000355072, ENST00000502820, ENST00000506137, ENST00000508321, ENST00000509043, ENST00000509618, ENST00000509751, ENST00000510626, ENST00000512068, ENST00000512909, ENST00000513326, ENST00000513639, ENST00000513806
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2218 1441 1304 223 1276 104 4020 1443 2871 239 1392 1572 135 1 1088 2475 5 2
Low 221 1549 422 401 674 361 337 754 863 180 68 41 40 116 313 1
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_009378 (Get FASTA)   NCBI Sequence Viewer