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Term:
regulatory ncRNA-mediated post-transcriptional gene silencing (GO:0035194)
Annotations: Rat: (269) Mouse: (341) Human: (674) Chinchilla: (56) Bonobo: (182) Dog: (345) Squirrel: (60) Pig: (285) Naked Mole-rat: (56) Green Monkey: (61)
Parent Terms Term With Siblings Child Terms
co-transcriptional gene silencing by RNA interference machinery  
global gene silencing by mRNA cleavage  
negative regulation of gene silencing by regulatory ncRNA +   
negative regulation of post-transcriptional gene silencing +   
positive regulation of post-transcriptional gene silencing +   
regulation of gene silencing by regulatory ncRNA +   
regulation of post-transcriptional gene silencing +   
regulatory ncRNA processing +   
regulatory ncRNA-mediated heterochromatin formation +   
regulatory ncRNA-mediated post-transcriptional gene silencing +   
A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.
RISC complex assembly  
target-directed miRNA degradation  

Synonyms
Exact Synonyms: RNA interference ;   RNA-dependent post-transcriptional gene silencing ;   RNA-mediated post-transcriptional gene silencing ;   RNA-mediated posttranscriptional gene silencing ;   RNAi ;   ncRNA-mediated post-transcriptional gene silencing ;   posttranscriptional gene silencing by RNA
Related Synonyms: PTGS ;   cosuppression ;   post-transcriptional gene silencing by RNA ;   quelling
Alternate IDs: GO:0016246
Xrefs: Wikipedia:RNA_interference
Never In Taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe ;   NCBITaxon:4932 ! Saccharomyces cerevisiae
Definition Sources: GOC:ems, PMID:11201747, PMID:11713190, PMID:15020054, PMID:15066275, PMID:18771919, PMID:32885814, PMID:33184244

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