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ONTOLOGY REPORT - ANNOTATIONS


Term:global gene silencing by mRNA cleavage
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Accession:GO:0098795 term browser browse the term
Definition:A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner.
Synonyms:exact_synonym: mRNA cleavage involved in gene silencing
 broad_synonym: gene silencing by mRNA cleavage
 related_synonym: RNA interference, targeting of mRNA for destruction;   mRNA destabilization-mediated gene silencing;   targeting of mRNA for destruction involved in RNA interference
 alt_id: GO:0030423



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global gene silencing by mRNA cleavage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 involved_in ISO
ISS
(PMID:17495927)
GO_REF:0000024
RGD
UniProt
PMID:17495927 GO_REF:0000024 NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:17531811) RGD PMID:17531811 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in ISO (PMID:15973356), (PMID:17452327) RGD PMID:15973356 PMID:17452327 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO
ISS
(PMID:15973356)
GO_REF:0000024
RGD
UniProt
PMID:15973356 GO_REF:0000024 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    negative regulation of biological process 5772
      negative regulation of metabolic process 3299
        negative regulation of macromolecule metabolic process 3067
          negative regulation of gene expression 1262
            post-transcriptional gene silencing 272
              global gene silencing by mRNA cleavage 4
Path 2
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      organic substance metabolic process 11023
        macromolecule metabolic process 9469
          gene expression 6179
            regulation of gene expression 4855
              negative regulation of gene expression 1262
                post-transcriptional gene silencing 272
                  global gene silencing by mRNA cleavage 4
paths to the root