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ONTOLOGY REPORT - ANNOTATIONS


Term:mRNA cleavage involved in gene silencing
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Accession:GO:0098795 term browser browse the term
Definition:Cleavage of an mRNA occurring as part of the mechanism of gene silencing.



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mRNA cleavage involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago1 argonaute RISC component 1 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in ISO
ISS
IEA
(PMID:15260970), (PMID:17524464), (PMID:18771919)
(MGI:5616320|PMID:16357216)
GO_REF:0000024
GO_REF:0000104
RGD
UniProt
PMID:15260970 PMID:16357216 PMID:17524464 PMID:18771919 GO_REF:0000024 GO_REF:0000104 MGI:5616320 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Ago3 argonaute RISC catalytic component 3 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Ago4 argonaute RISC component 4 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,780,450...138,825,889
Ensembl chr 5:138,783,069...138,825,632
JBrowse link
G Mir196a microRNA 196a acts_upstream_of_or_within ISO (MGI:3042528|PMID:15105502), (MGI:3510301|PMID:15361871) RGD PMID:15105502 PMID:15361871 MGI:3042528 MGI:3510301 NCBI chr 7:134,110,400...134,110,509
Ensembl chr 7:134,110,400...134,110,509
JBrowse link
G Mir196b microRNA 196b acts_upstream_of_or_within ISO (MGI:3042528|PMID:15105502) RGD PMID:15105502 MGI:3042528 NCBI chr 4:81,330,487...81,330,571 JBrowse link
G Mir196c microRNA 196c acts_upstream_of_or_within ISO (MGI:3042528|PMID:15105502), (MGI:3510301|PMID:15361871) RGD PMID:15105502 PMID:15361871 MGI:3042528 MGI:3510301 NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase involved_in ISO (PMID:16289642) RGD PMID:16289642 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
JBrowse link
mRNA cleavage involved in gene silencing by siRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago1 argonaute RISC component 1 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
JBrowse link
G Ago2 argonaute RISC catalytic component 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:15260970), (PMID:22795694)
Ensembl
RGD
PMID:15260970 PMID:22795694 GO_REF:0000107 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Ago3 argonaute RISC catalytic component 3 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Ago4 argonaute RISC component 4 NOT|involved_in ISO (PMID:15260970) RGD PMID:15260970 NCBI chr 5:138,780,450...138,825,889
Ensembl chr 5:138,783,069...138,825,632
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    negative regulation of biological process 5622
      negative regulation of metabolic process 3185
        negative regulation of macromolecule metabolic process 2958
          negative regulation of gene expression 1124
            gene silencing 267
              mRNA cleavage involved in gene silencing 8
                mRNA cleavage involved in gene silencing by miRNA 8
                mRNA cleavage involved in gene silencing by siRNA 4
Path 2
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      cellular metabolic process 10733
        cellular aromatic compound metabolic process 5604
          nucleobase-containing compound metabolic process 5383
            nucleic acid metabolic process 4892
              RNA metabolic process 4362
                mRNA metabolic process 653
                  mRNA cleavage 24
                    mRNA cleavage involved in gene silencing 8
                      mRNA cleavage involved in gene silencing by miRNA 8
                      mRNA cleavage involved in gene silencing by siRNA 4
paths to the root