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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of gene silencing by RNA
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Accession:GO:0060966 term browser browse the term
Definition:Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.



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negative regulation of gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in ISO
IBA
(PMID:18155131)
PMID:21873635
RGD PMID:18155131 PMID:21873635 RGD:13792537 NCBI chr18:28,378,692...28,381,316
Ensembl chr18:28,378,692...28,381,316
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 involved_in ISO
ISS
RNAcentral:URS000024463E_9606 (PMID:26595526), (PMID:27089893)
GO_REF:0000024
RGD
UniProt
PMID:26595526 PMID:27089893 GO_REF:0000024 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19409607) RGD PMID:19409607 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase involved_in ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 acts_upstream_of ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lin28b lin-28 homolog B involved_in ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:48,865,329...48,964,769
Ensembl chr20:48,869,485...48,955,077
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 involved_in ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20388878)
Ensembl
RGD
PMID:20388878 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 involved_in ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:5562625 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343 PMID:31824476 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 involved_in ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:973,415...977,742
Ensembl chr 7:972,855...979,349
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(PMID:22055188)
UniProt
RGD
PMID:22055188 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tert telomerase reverse transcriptase involved_in ISO (PMID:19701182) RGD PMID:19701182 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
negative regulation of RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3573853|PMID:15556947)
Ensembl
RGD
PMID:15556947 GO_REF:0000107 MGI:3573853 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
JBrowse link
positive regulation of gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002945.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:86,731,265...86,765,014 JBrowse link
G Ajuba ajuba LIM protein involved_in ISO
IBA
ISS
(PMID:20616046)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20616046 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:17531811) RGD PMID:17531811 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Fmr1 FMRP translational regulator 1 involved_in ISO
ISS
IEA
(PMID:17057366)
(MGI:4868681|PMID:20159450)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17057366 PMID:20159450 GO_REF:0000024 GO_REF:0000107 MGI:4868681 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fxr1 FMR1 autosomal homolog 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17057366)
UniProt
Ensembl
RGD
PMID:17057366 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:116,884,167...116,937,586
Ensembl chr 2:116,884,248...116,937,590
JBrowse link
G Limd1 LIM domain containing 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20616046)
UniProt
RGD
PMID:20616046 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:123,122,460...123,167,714
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IMP PMID:24676391 BHF-UCL PMID:24676391 RGD:10400879 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Pum1 pumilio RNA-binding family member 1 involved_in ISO (PMID:20818387), (PMID:22345517) RGD PMID:20818387 PMID:22345517 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
JBrowse link
G Pum2 pumilio RNA-binding family member 2 involved_in ISO (PMID:22345517) RGD PMID:22345517 NCBI chr 6:31,462,879...31,542,976
Ensembl chr 6:31,462,872...31,542,976
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:23820254) RGD PMID:23820254 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 involved_in ISO
IEA
FB:FBgn0005649 (PMID:33203680)
GO_REF:0000107
RGD
Ensembl
PMID:33203680 GO_REF:0000107 NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:183,009,253...183,031,637
JBrowse link
G Trim71 tripartite motif containing 71 acts_upstream_of_or_within ISO (MGI:4438512|PMID:19898466) RGD PMID:19898466 MGI:4438512 NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807
JBrowse link
G Wtip WT1 interacting protein involved_in ISO (PMID:20616046) RGD PMID:20616046 NCBI chr 1:86,731,214...86,764,939 JBrowse link
G Zfp36 zinc finger protein 36 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15766526)
UniProt
Ensembl
RGD
PMID:15766526 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
positive regulation of miRNA mediated inhibition of translation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 involved_in ISO
IEA
(PMID:23409027)
GO_REF:0000107
RGD
Ensembl
PMID:23409027 GO_REF:0000107 NCBI chr 7:105,018,202...105,105,120
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Ddx6 DEAD-box helicase 6 involved_in ISO (PMID:27342281) RGD PMID:27342281 NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405
JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:28487484) RGD PMID:28487484 NCBI chr 9:87,886,078...87,901,058
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 involved_in ISO (PMID:24335285), (PMID:27342281), (PMID:28487484), (PMID:32354837) RGD PMID:24335285 PMID:27342281 PMID:28487484 PMID:32354837 NCBI chr14:78,056,115...78,099,846
Ensembl chr14:78,056,297...78,098,793
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 involved_in ISO (PMID:23409027) RGD PMID:23409027 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO (PMID:23820254) RGD PMID:23820254 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B involved_in ISO (PMID:32354837) RGD PMID:32354837 NCBI chr 7:112,252,351...112,469,829
Ensembl chr 7:112,252,359...112,461,790
JBrowse link
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:18548003)
Ensembl
RGD
PMID:18548003 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:21673316) RGD PMID:21673316 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:27252421) RGD PMID:27252421 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lin28a lin-28 homolog A involved_in ISO (MGI:5294254|PMID:21962509) RGD PMID:21962509 MGI:5294254 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in ISO
IEA
(PMID:24375836)
GO_REF:0000107
RGD
Ensembl
PMID:24375836 GO_REF:0000107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in ISO (PMID:24375836) RGD PMID:24375836 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Myocd myocardin involved_in IEA
ISO
GO_REF:0000107
(MGI:6414695|PMID:28342807)
Ensembl
RGD
PMID:28342807 GO_REF:0000107 MGI:6414695 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 acts_upstream_of_or_within ISO MGI:2385930 (MGI:5574156|PMID:24349493) RGD PMID:24349493 MGI:5574156 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:26020802) RGD PMID:26020802 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:18548003) RGD PMID:18548003 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:22578566), (PMID:26100857) RGD PMID:22578566 PMID:26100857 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xpo5 exportin 5 involved_in ISO (PMID:15613540) RGD PMID:15613540 NCBI chr 9:14,740,182...14,778,171
Ensembl chr 9:14,740,182...14,778,171
JBrowse link
regulation of gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmr1 FMRP translational regulator 1 involved_in ISO
ISS
(PMID:25464849)
GO_REF:0000024
RGD
UniProt
PMID:25464849 GO_REF:0000024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Lin28a lin-28 homolog A acts_upstream_of_or_within ISO MGI:2685973 (MGI:4438512|PMID:19898466) RGD PMID:19898466 MGI:4438512 NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122
JBrowse link
G Mael maelstrom spermatogenic transposon silencer involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:78,457,073...78,496,657
Ensembl chr13:78,457,073...78,496,657
JBrowse link
G Mir154 microRNA 154 acts_upstream_of_or_within ISO (MGI:5705446|PMID:25959411) RGD PMID:25959411 MGI:5705446 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C acts_upstream_of_or_within ISO MGI:4124681 (MGI:5315650|PMID:22187428) RGD PMID:22187428 MGI:5315650 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194
JBrowse link
G Trim71 tripartite motif containing 71 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5448492|PMID:22735451)
MGI:1890546 (MGI:4438512|PMID:19898466)
UniProt
RGD
PMID:19898466 PMID:22735451 GO_REF:0000024 MGI:4438512 MGI:5448492 NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807
JBrowse link
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 TARBP2 subunit of RISC loading complex acts_upstream_of_or_within ISO MGI:2135565|MGI:5645258 (MGI:6094668|PMID:27159388) RGD PMID:27159388 MGI:6094668 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 TARBP2 subunit of RISC loading complex involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    regulation of biological process 12770
      regulation of metabolic process 6748
        regulation of macromolecule metabolic process 6253
          regulation of gene expression 4818
            regulation of gene silencing 77
              regulation of gene silencing by RNA 54
                negative regulation of gene silencing by RNA + 21
                regulation of RNA interference + 3
                regulation of gene silencing by miRNA + 50
                regulation of production of small RNA involved in gene silencing by RNA + 26
Path 2
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      organic substance metabolic process 11356
        macromolecule metabolic process 9809
          gene expression 6300
            regulation of gene expression 4818
              negative regulation of gene expression 1124
                gene silencing 267
                  gene silencing by RNA 151
                    regulation of gene silencing by RNA 54
                      negative regulation of gene silencing by RNA + 21
                      regulation of RNA interference + 3
                      regulation of gene silencing by miRNA + 50
                      regulation of production of small RNA involved in gene silencing by RNA + 26
paths to the root