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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:argatroban pharmacodynamics pathway
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Accession:PW:0002229 term browser browse the term
Definition:The pathway of argatroban-target interaction and of the biochemical or physiological responses to drug. The drug is a direct thrombin inhibitor. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00276


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argatroban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO SMPDB SMP:00276 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00276 NCBI chr13:94,263,202...94,289,612
Ensembl chr13:113,332,124...113,358,660 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00276 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00276 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G F13A1 coagulation factor XIII A chain ISO SMPDB SMP:00276 NCBI chr 6:5,978,505...6,156,705
Ensembl chr 6:6,157,926...6,513,961 		JBrowse link
G F13B coagulation factor XIII B chain ISO SMPDB SMP:00276 NCBI chr 1:172,623,336...172,651,945
Ensembl chr 1:176,937,158...176,965,773 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00276 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00276 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00276 NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00276 NCBI chr13:94,246,694...94,261,133
Ensembl chr13:113,315,868...113,329,995 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00276 NCBI chr  X:144,316,192...144,505,773
Ensembl chr  X:154,156,873...154,341,317 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00276 NCBI chr  X:128,684,709...128,719,020
Ensembl chr  X:138,934,167...138,967,087 		JBrowse link
G FGA fibrinogen alpha chain ISO SMPDB SMP:00276 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain ISO SMPDB SMP:00276 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766 		JBrowse link
G FGG fibrinogen gamma chain ISO SMPDB SMP:00276 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237 		JBrowse link
G GGCX gamma-glutamyl carboxylase ISO SMPDB SMP:00276 NCBI chr2A:85,599,227...85,612,274
Ensembl chr2A:87,152,111...87,164,567 		JBrowse link
G KLKB1 kallikrein B1 ISO SMPDB SMP:00276 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300 		JBrowse link
G LOC100982214 plasminogen ISO SMPDB SMP:00276 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G PLAT plasminogen activator, tissue type ISO SMPDB SMP:00276 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 ISO SMPDB SMP:00276 NCBI chr16:23,871,756...23,876,599
Ensembl chr16:31,459,560...31,464,897 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4064
    drug pathway 395
      blood and blood forming organs drug pathway 60
        antithrombotic drug pathway 60
          anticoagulant drug pathway 27
            direct thrombin inhibitor drug pathway 20
              argatrobran drug pathway 20
                argatroban pharmacodynamics pathway 20
paths to the root