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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:angiotensin (1-7) signaling pathway
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Accession:PW:0000529 term browser browse the term
Definition:Angiotensin (1-7) is derived from angiotensin II through the action of angiotensin converting enzyme 2 (ACE2) or from angiotensin I through the action of neutral endopeptidase (NEP). Angiotensin (1-7) signaling appears to have a vasodilatory effect but the exact action of this peptide in humans remains to be established.


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angiotensin (1-7) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP
ISO		 RGD PMID:10642323 PMID:15283675 RGD:1581953, RGD:1598433 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 ISO RGD PMID:15638741 RGD:1581742 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Agt angiotensinogen IMP RGD PMID:15951342 RGD:1581938 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IMP
ISO		 RGD PMID:15951342 PMID:16520407 RGD:1581938, RGD:1581931 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mme membrane metallo-endopeptidase ISO
IMP		 RGD PMID:15638741 PMID:16520407 PMID:10642323 RGD:1581742, RGD:1581931, RGD:1581953 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2635
      hormone signaling pathway 624
        peptide and protein hormone signaling pathway 439
          angiotensin signaling pathway 41
            angiotensin (1-7) signaling pathway 5
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3867
      homeostasis pathway 1773
        cardiovascular system homeostasis pathway 423
          renin-angiotensin cascade pathway 52
            angiotensin signaling pathway 41
              angiotensin (1-7) signaling pathway 5
paths to the root