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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of retinal ganglion cell axon guidance
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Accession:GO:0090260 term browser browse the term
Definition:Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
Comment:Note that growth cone collapse has been observed only in assays performed in vitro.
Synonyms:related_synonym: axon growth cone collapse


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negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPRO protein tyrosine phosphatase receptor type O involved_in ISS UniProt GO_REF:0000024 NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IDA (PMID:17062560) UniProt PMID:17062560 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    locomotion 1544
      negative regulation of locomotion 493
        negative regulation of chemotaxis 69
          negative regulation of axon guidance 2
            negative regulation of retinal ganglion cell axon guidance 2
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7618
      anatomical structure development 7029
        multicellular organism development 5641
          system development 4919
            nervous system development 3058
              neurogenesis 2140
                generation of neurons 1853
                  neuron differentiation 1769
                    neuron development 1454
                      neuron projection development 1274
                        neuron projection morphogenesis 792
                          axonogenesis 556
                            axon guidance 289
                              retinal ganglion cell axon guidance 24
                                regulation of retinal ganglion cell axon guidance 4
                                  negative regulation of retinal ganglion cell axon guidance 2
paths to the root