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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chemotaxis
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Accession:GO:0050922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
Synonyms:exact_synonym: down regulation of chemotaxis;   downregulation of chemotaxis
 narrow_synonym: inhibition of chemotaxis


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negative regulation of chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp3 dual specificity phosphatase 3 involved_in ISO (PMID:28759036) RGD PMID:28759036 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3029644|PMID:14966296)
UniProt
RGD
PMID:14966296 GO_REF:0000024 MGI:3029644 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 IDA RGD PMID:11559557 RGD:10043143 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
negative regulation of axon extension involved in axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 IMP RGD PMID:19884510 RGD:9681717 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Nrp1 neuropilin 1 acts_upstream_of_or_within IMP
ISO
(MGI:1289520|PMID:9753685) RGD PMID:9753685 PMID:9288754 MGI:1289520, RGD:633436 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Plxna3 plexin A3 acts_upstream_of_or_within ISO MGI:107558|MGI:1096347 (MGI:2152659|PMID:11683995) RGD PMID:11683995 MGI:2152659 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Ryk receptor-like tyrosine kinase acts_upstream_of_or_within ISO MGI:98958 (MGI:3625635|PMID:16723543) RGD PMID:16723543 MGI:3625635 NCBI chr 8:103,419,348...103,492,083
Ensembl chr 8:103,419,275...103,491,698
JBrowse link
G Sema3a semaphorin 3A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:104518|MGI:107683|MGI:96721 (MGI:1289520|PMID:9753685), (MGI:2152659|PMID:11683995), (MGI:3801368|PMID:18550718), (MGI:73216|PMID:7748561)
RGD PMID:7748561 PMID:9753685 PMID:11683995 PMID:18550718 PMID:21873635 MGI:1289520 MGI:2152659 MGI:3801368 MGI:73216, RGD:13792537 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Sema3b semaphorin 3B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:108,271,663...108,280,326
Ensembl chr 8:108,271,666...108,282,919
JBrowse link
G Sema3c semaphorin 3C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
JBrowse link
G Sema3d semaphorin 3D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930
JBrowse link
G Sema3e semaphorin 3E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229
JBrowse link
G Sema3f semaphorin 3F involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:107683 (MGI:1289520|PMID:9753685), (MGI:2152659|PMID:11683995)
RGD PMID:9753685 PMID:11683995 PMID:21873635 MGI:1289520 MGI:2152659, RGD:13792537 NCBI chr 8:108,357,629...108,387,083
Ensembl chr 8:108,357,629...108,387,083
JBrowse link
G Sema3g semaphorin 3G involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:6,413,589...6,425,221
Ensembl chr16:6,413,589...6,425,221
JBrowse link
G Sema4a semaphorin 4A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442
JBrowse link
G Sema4b semaphorin 4B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:134,136,646...134,177,777
Ensembl chr 1:134,149,536...134,177,775
JBrowse link
G Sema4c semaphorin 4C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128
JBrowse link
G Sema4d semaphorin 4D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
JBrowse link
G Sema4f ssemaphorin 4F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,411,411...115,437,721
Ensembl chr 4:115,411,417...115,437,721
JBrowse link
G Sema4g semaphorin 4G involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:243,849,979...243,865,343
Ensembl chr 1:243,853,854...243,865,341
JBrowse link
G Sema5a semaphorin 5A involved_in IBA
IMP
PMID:21873635
PMID:15603739
GO_Central
UniProt
PMID:21873635 PMID:15603739 RGD:13792537, RGD:8553809 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Sema5b semaphorin 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:65,102,031...65,225,456
Ensembl chr11:65,102,031...65,225,311
JBrowse link
G Sema6a semaphorin 6A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
JBrowse link
G Sema6b semaphorin 6B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
JBrowse link
G Sema6c semaphorin 6C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:182,733,635...182,750,066
Ensembl chr 2:182,737,474...182,746,856
JBrowse link
G Sema6d semaphorin 6D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536
JBrowse link
G Slit1 slit guidance ligand 1 IDA RGD PMID:15632296 RGD:1358459 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
JBrowse link
G Wnt3 Wnt family member 3 acts_upstream_of_or_within ISO (MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:3806438 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:3806438 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:101766 (MGI:3625635|PMID:16723543)
Ensembl
RGD
PMID:16723543 GO_REF:0000107 MGI:3625635 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
negative regulation of dendritic cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:5752697 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
JBrowse link
negative regulation of endothelial cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hrg histidine-rich glycoprotein involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:14744774), (PMID:16436387), (PMID:16489009)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:14744774 PMID:16436387 PMID:16489009 GO_REF:0000024 GO_REF:0000107 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Notch1 notch receptor 1 involved_in ISO
ISS
(PMID:20616313)
GO_REF:0000024
RGD
UniProt
PMID:20616313 GO_REF:0000024 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of_or_within ISO (PMID:16150726) RGD PMID:16150726 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of endothelial cell chemotaxis to fibroblast growth factor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in ISO (PMID:11708770) RGD PMID:11708770 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
negative regulation of leukocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr18 G protein-coupled receptor 18 acts_upstream_of_or_within ISO MGI:5708707 (MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:5629467 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist IDA RGD PMID:15528323 RGD:2303400 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (PMID:11309622) RGD PMID:11309622 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
negative regulation of lymphocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi2 peptidyl arginine deiminase 2 involved_in ISO
IEA
(PMID:18645041)
GO_REF:0000107
RGD
Ensembl
PMID:18645041 GO_REF:0000107 NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632
JBrowse link
negative regulation of macrophage chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5 complement C5 involved_in ISO
IEA
(PMID:14566334)
GO_REF:0000107
RGD
Ensembl
PMID:14566334 GO_REF:0000107 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857043 (MGI:5610078|PMID:25447050)
Ensembl
RGD
PMID:25447050 GO_REF:0000107 MGI:5610078 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Ddt D-dopachrome tautomerase involved_in ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mmp28 matrix metallopeptidase 28 acts_upstream_of_or_within ISO MGI:3836773 (MGI:3836320|PMID:19265166) RGD PMID:19265166 MGI:3836320 NCBI chr10:68,243,748...68,264,728
Ensembl chr10:68,241,138...68,264,866
JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:5752697 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
JBrowse link
negative regulation of mast cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rin3 Ras and Rab interactor 3 acts_upstream_of ISO (PMID:23185384) RGD PMID:23185384 NCBI chr 6:121,431,803...121,540,957
Ensembl chr 6:121,431,339...121,540,957
JBrowse link
negative regulation of monocyte chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 involved_in ISO
ISS
(PMID:21063504)
GO_REF:0000024
RGD
UniProt
PMID:21063504 GO_REF:0000024 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Dusp1 dual specificity phosphatase 1 involved_in ISO (PMID:22991462) RGD PMID:22991462 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IDA PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IEA
ISO
GO_REF:0000107
(MGI:5318030|PMID:15528323)
Ensembl
RGD
PMID:15528323 GO_REF:0000107 MGI:5318030 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:5752697 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
JBrowse link
G Slit2 slit guidance ligand 2 involved_in IDA PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
negative regulation of natural killer cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 involved_in ISO (PMID:7545673) RGD PMID:7545673 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in ISO (PMID:22585739) RGD PMID:22585739 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in IEA
ISO
GO_REF:0000107
(PMID:22585739)
Ensembl
RGD
PMID:22585739 GO_REF:0000107 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
negative regulation of negative chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Robo1 roundabout guidance receptor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:11748139)
Ensembl
RGD
PMID:11748139 GO_REF:0000107 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203
JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO (PMID:11748139) RGD PMID:11748139 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536
JBrowse link
negative regulation of neutrophil chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar2 complement C5a receptor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:16204243)
UniProt
RGD
PMID:16204243 GO_REF:0000024 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517
JBrowse link
G Dpp4 dipeptidylpeptidase 4 involved_in ISO (PMID:23677473) RGD PMID:23677473 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA
(PMID:19759280)
GO_REF:0000107
RGD
Ensembl
PMID:19759280 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
negative regulation of positive chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt2 angiopoietin 2 involved_in ISO (PMID:9660821) RGD PMID:9660821 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 involved_in ISO
IEA
(PMID:17062560)
GO_REF:0000107
RGD
Ensembl
PMID:17062560 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
negative regulation of smooth muscle cell chemotaxis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 involved_in ISO (PMID:22116621) RGD PMID:22116621 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Coro1b coronin 1B involved_in ISO
IEA
IMP
(PMID:22619279)
GO_REF:0000107
RGD
Ensembl
PMID:22619279 PMID:22619279 GO_REF:0000107, RGD:10047170 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:24321768 RGD:10401938 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA
(PMID:16439689)
GO_REF:0000107
RGD
Ensembl
PMID:16439689 GO_REF:0000107 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    locomotion 1952
      negative regulation of locomotion 351
        negative regulation of chemotaxis 62
          negative regulation of Schwann cell chemotaxis 0
          negative regulation of astrocyte chemotaxis 0
          negative regulation of axon extension involved in axon guidance 28
          negative regulation of axon guidance + 1
          negative regulation of cell chemotaxis to fibroblast growth factor + 1
          negative regulation of chemokine activity 0
          negative regulation of chemotaxis to arachidonic acid 0
          negative regulation of endothelial cell chemotaxis + 5
          negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
          negative regulation of fibroblast chemotaxis 0
          negative regulation of leukocyte chemotaxis + 20
          negative regulation of muscle cell chemotaxis toward tendon cell 0
          negative regulation of negative chemotaxis + 2
          negative regulation of positive chemotaxis + 1
          negative regulation of smooth muscle cell chemotaxis 4
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of response to stimulus 3978
          regulation of response to external stimulus 938
            regulation of chemotaxis 241
              negative regulation of chemotaxis 62
                negative regulation of Schwann cell chemotaxis 0
                negative regulation of astrocyte chemotaxis 0
                negative regulation of axon extension involved in axon guidance 28
                negative regulation of axon guidance + 1
                negative regulation of cell chemotaxis to fibroblast growth factor + 1
                negative regulation of chemokine activity 0
                negative regulation of chemotaxis to arachidonic acid 0
                negative regulation of endothelial cell chemotaxis + 5
                negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
                negative regulation of fibroblast chemotaxis 0
                negative regulation of leukocyte chemotaxis + 20
                negative regulation of muscle cell chemotaxis toward tendon cell 0
                negative regulation of negative chemotaxis + 2
                negative regulation of positive chemotaxis + 1
                negative regulation of smooth muscle cell chemotaxis 4
paths to the root