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ONTOLOGY REPORT - ANNOTATIONS

Term:cytoskeleton of presynaptic active zone
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Accession:GO:0048788 term browser browse the term
Definition:The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.
Synonyms:exact_synonym: active zone cytomatrix;   presynaptic cytomatrix assembled at active zones;   presynaptic cytoskeletal matrix;   presynaptic cytoskeletal matrix assembled at active zones
 narrow_synonym: CAZ;   T-bar;   T-bar ribbon;   pre-synaptic dense body;   presynaptic dense body;   synaptic ribbon
 related_synonym: pre-synaptic cytoskeletal matrix assembled at active zones;   pre-synaptic ribbon;   presynaptic ribbon;   ribbon
 xref: NIF_Subcellular:sao1470121605


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cytoskeleton of presynaptic active zone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bsn bassoon located_in
is_active_in		 ISO
IBA		 MGI
GO_Central
RGD		 PMID:11596050 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:9850129 NCBI chr 9:107,973,221...108,067,618
Ensembl chr 9:107,973,221...108,067,583 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 6:119,547,757...119,830,985
Ensembl chr 6:119,547,757...119,825,128 		JBrowse link
G Erc2 ELKS/RAB6-interacting/CAST family member 2 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr14:27,344,232...28,200,494
Ensembl chr14:27,344,385...28,200,494 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) located_in
is_active_in		 ISO
IBA		 MGI
GO_Central
RGD		 PMID:11596050 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:9850129 NCBI chr 5:14,564,924...14,913,479
Ensembl chr 5:14,564,932...14,913,473 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:22,356,196...22,845,239
Ensembl chr 1:22,356,475...22,845,203 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr15:39,061,681...39,547,768
Ensembl chr15:39,061,656...39,547,768 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 4:120,711,976...120,753,777
Ensembl chr 4:120,712,013...120,753,776 		JBrowse link
G Rims4 regulating synaptic membrane exocytosis 4 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:163,701,676...163,760,893
Ensembl chr 2:163,701,671...163,760,603 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19618
      presynaptic active zone 143
        presynaptic active zone cytoplasmic component 23
          cytoskeleton of presynaptic active zone 8
            presynaptic density + 0
Path 2
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19618
      organelle 13554
        non-membrane-bounded organelle 4911
          intracellular non-membrane-bounded organelle 4909
            cytoskeleton 2375
              cortical cytoskeleton 125
                cytoskeleton of presynaptic active zone 8
                  presynaptic density + 0
paths to the root