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Gene: Erc1 (ELKS/RAB6-interacting/CAST family member 1) Mus musculus
Symbol: Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Description: Exhibits Rab GTPase binding activity and voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. Involved in calcium ion transmembrane transport; chemical synaptic transmission; and retrograde transport, endosome to Golgi. Localizes to GABA-ergic synapse; cytoplasm; and glutamatergic synapse. Orthologous to human ERC1 (ELKS/RAB6-interacting/CAST family member 1); PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST2; CAZ-associated structural protein 2; ELKS; Elks1; ERC-1; mKIAA1081; Rab6 interacting protein 2; RAB6-interacting protein 2; Rab6ip2; RAB6IP2A; RAB6IP2B
Homo sapiens (human) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Canis lupus familiaris (dog) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Sus scrofa (pig) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Chlorocebus sabaeus (African green monkey) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Heterocephalus glaber (naked mole-rat) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl6119,570,796 - 119,848,167 (-)EnsemblGRCm38mm10GRCm38
GRCm386119,570,796 - 119,848,184 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376119,520,814 - 119,798,168 (-)NCBIGRCm37mm9NCBIm37
MGSCv366119,540,864 - 119,813,753 (-)NCBImm8
Celera6121,405,104 - 121,685,429 (-)NCBICelera
Cytogenetic Map6F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Erc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731980
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.