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Gene: Erc1 (ELKS/RAB6-interacting/CAST family member 1) Mus musculus
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Symbol: Erc1
Name: ELKS/RAB6-interacting/CAST family member 1
Description: Exhibits Rab GTPase binding activity and voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. Involved in calcium ion transmembrane transport; chemical synaptic transmission; and retrograde transport, endosome to Golgi. Localizes to GABA-ergic synapse; cytoplasm; and glutamatergic synapse. Orthologous to human ERC1 (ELKS/RAB6-interacting/CAST family member 1); PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930404L01Rik; 5033405M01Rik; 9630025C19Rik; B430107L16Rik; CAST2; CAZ-associated structural protein 2; ELKS; Elks1; ERC-1; mKIAA1081; Rab6 interacting protein 2; RAB6-interacting protein 2; Rab6ip2; RAB6IP2A; RAB6IP2B
Orthologs:
Homo sapiens (human) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Canis lupus familiaris (dog) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
Sus scrofa (pig) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Chlorocebus sabaeus (African green monkey) : ERC1 (ELKS/RAB6-interacting/CAST family member 1)
Heterocephalus glaber (naked mole-rat) : Erc1 (ELKS/RAB6-interacting/CAST family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl6119,570,796 - 119,848,167 (-)EnsemblGRCm38mm10GRCm38
GRCm386119,570,796 - 119,848,184 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376119,520,814 - 119,798,168 (-)NCBIGRCm37mm9NCBIm37
MGSCv366119,540,864 - 119,813,753 (-)NCBImm8
Celera6121,405,104 - 121,685,429 (-)NCBICelera
Cytogenetic Map6F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Erc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731980
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.