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ONTOLOGY REPORT - ANNOTATIONS

Term:T cell receptor complex
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Accession:GO:0042101 term browser browse the term
Definition:A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
Synonyms:exact_synonym: T lymphocyte receptor complex;   TCR complex
 related_synonym: TCR
 xref: Wikipedia:T_cell_receptor


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T cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALCAM activated leukocyte cell adhesion molecule part_of
located_in		 IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr33:10,983,363...11,195,170
Ensembl chr33:10,983,363...11,370,085 		JBrowse link
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein part_of IEA Ensembl GO_REF:0000107 NCBI chr 2:7,151,443...7,250,412
Ensembl chr 2:7,151,443...7,212,200 		JBrowse link
G CD247 CD247 molecule part_of ISO
IEA		 RGD
Ensembl		 PMID:8409430 GO_REF:0000107 RGD:634717 NCBI chr 7:30,961,169...30,972,143 JBrowse link
G CD3D CD3 delta subunit of T-cell receptor complex part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:15,392,841...15,396,745
Ensembl chr 5:15,389,243...15,396,750 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex part_of ISO (PMID:8176201) MGI PMID:8176201 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD6 CD6 molecule part_of
located_in		 IEA
ISO		 (PMID:15294938) Ensembl
UniProt		 PMID:15294938 GO_REF:0000107 NCBI chr18:55,296,116...55,336,014
Ensembl chr18:55,296,986...55,335,880 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 located_in ISO (PMID:18424730) UniProt PMID:18424730 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G SKAP1 src kinase associated phosphoprotein 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:24,412,820...24,700,579
Ensembl chr 9:24,412,820...24,700,734 		JBrowse link
G SYK spleen associated tyrosine kinase part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TRAT1 T cell receptor associated transmembrane adaptor 1 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr33:14,033,597...14,068,309
Ensembl chr33:14,033,657...14,067,974 		JBrowse link
G TRAV19 T cell receptor alpha variable 19 part_of IEA UniProt GO_REF:0000043 Ensembl chr 8:2,472,488...2,473,101 JBrowse link
G TRAV21 T cell receptor alpha variable 21 part_of IEA UniProt GO_REF:0000043 Ensembl chr 8:2,496,960...2,497,250 JBrowse link
G TRAV21 T cell receptor alpha variable 21 part_of IEA UniProt GO_REF:0000043
G TRAV24 T cell receptor alpha variable 24 part_of IEA UniProt GO_REF:0000043
G TRAV29DV5 T cell receptor alpha variable 29/delta variable 5 part_of IEA UniProt GO_REF:0000043
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 part_of IEA Ensembl GO_REF:0000107 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071 		JBrowse link
alpha-beta T cell receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD247 CD247 molecule located_in
part_of		 ISO
IEA		 (PMID:31461748) ComplexPortal
Ensembl
TreeGrafter		 PMID:31461748 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:30,961,169...30,972,143 JBrowse link
G CD3D CD3 delta subunit of T-cell receptor complex located_in
part_of		 ISO
IEA		 (PMID:31461748) ComplexPortal
UniProt
Ensembl
TreeGrafter		 PMID:31461748 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 5:15,392,841...15,396,745
Ensembl chr 5:15,389,243...15,396,750 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex located_in
part_of		 ISO
IEA
IBA		 (PMID:31461748) ComplexPortal
UniProt
TreeGrafter
GO_Central		 PMID:31461748 GO_REF:0000033 GO_REF:0000117 GO_REF:0000118 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260 		JBrowse link
G CD3G CD3 gamma subunit of T-cell receptor complex located_in
part_of		 ISO
IEA		 (PMID:31461748) ComplexPortal
Ensembl
UniProt
TreeGrafter		 PMID:31461748 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 5:15,379,788...15,391,271
Ensembl chr 5:15,380,633...15,391,214 		JBrowse link
G LOC607937 T cell receptor alpha variable 9-2 located_in ISO (PMID:31461748) ComplexPortal PMID:31461748 NCBI chr 8:2,894,910...2,952,126 JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 part_of IEA Ensembl GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G TRBV19 T cell receptor beta variable 19 part_of IEA Ensembl GO_REF:0000107
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18906
    protein-containing complex 6506
      receptor complex 415
        plasma membrane signaling receptor complex 198
          T cell receptor complex 20
            alpha-beta T cell receptor complex 7
            gamma-delta T cell receptor complex 0
Path 2
Term Annotations click to browse term
  cellular_component 18906
    cellular anatomical entity 18654
      cell periphery 5883
        plasma membrane 5399
          plasma membrane protein complex 603
            plasma membrane signaling receptor complex 198
              T cell receptor complex 20
                alpha-beta T cell receptor complex 7
                gamma-delta T cell receptor complex 0
paths to the root