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ONTOLOGY REPORT - ANNOTATIONS

Term:T cell receptor V(D)J recombination
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Accession:GO:0033153 term browser browse the term
Definition:The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
Synonyms:exact_synonym: TCR V(D)J recombination
 narrow_synonym: T cell receptor V-D-J joining;   T cell receptor V-J joining;   T cell receptor V-J recombination


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T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL11B BCL11 transcription factor B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12717433) Ensembl
MGI		 PMID:12717433 GO_REF:0000107 NCBI chr14:99,169,287...99,272,197
Ensembl chr14:99,169,287...99,272,197 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9462507) Ensembl
MGI		 PMID:9462507 GO_REF:0000107 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956 		JBrowse link
G LIG4 DNA ligase 4 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:10911993) UniProt
MGI
Ensembl		 PMID:10911993 GO_REF:0000024 GO_REF:0000107 NCBI chr13:108,207,442...108,218,349
Ensembl chr13:108,207,439...108,218,368 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9768755) Ensembl
MGI		 PMID:9768755 GO_REF:0000107 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G TCF7 transcription factor 7 acts_upstream_of_or_within ISO (PMID:9462507) MGI PMID:9462507 NCBI chr 5:134,108,218...134,148,210
Ensembl chr 5:134,114,681...134,151,865 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    immune system process 3226
      somatic diversification of immune receptors 90
        somatic diversification of immune receptors via germline recombination within a single locus 81
          somatic recombination of T cell receptor gene segments 5
            T cell receptor V(D)J recombination 5
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7618
      cellular developmental process 5184
        cell differentiation 5183
          cell development 3452
            hemopoiesis 1167
              leukocyte differentiation 749
                mononuclear cell differentiation 620
                  lymphocyte differentiation 513
                    T cell differentiation 365
                      somatic diversification of T cell receptor genes 5
                        somatic recombination of T cell receptor gene segments 5
                          T cell receptor V(D)J recombination 5
paths to the root