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ONTOLOGY REPORT - ANNOTATIONS


Term:somatic diversification of T cell receptor genes
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Accession:GO:0002568 term browser browse the term
Definition:The somatic process that results in the generation of sequence diversity of T cell receptor genes.
Synonyms:exact_synonym: somatic diversification of TCR genes



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T cell receptor V(D)J recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BAF chromatin remodeling complex subunit BCL11B acts_upstream_of_or_within ISO MGI:2663971 (MGI:2662810|PMID:12717433) RGD PMID:12717433 MGI:2662810 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 acts_upstream_of_or_within ISO MGI:98507 (MGI:3640275|PMID:9462507) RGD PMID:9462507 MGI:3640275 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (MGI:1860400|PMID:10911993) RGD PMID:10911993 MGI:1860400 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit acts_upstream_of_or_within ISO MGI:2383951 (MGI:1290043|PMID:9768755) RGD PMID:9768755 MGI:1290043 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Tcf7 transcription factor 7 acts_upstream_of_or_within ISO MGI:96770 (MGI:3640275|PMID:9462507) RGD PMID:9462507 MGI:3640275 NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    immune system process 2730
      somatic diversification of immune receptors 86
        somatic diversification of T cell receptor genes 5
          somatic diversification of T cell receptor genes by N region addition 0
          somatic recombination of T cell receptor gene segments + 5
Path 2
Term Annotations click to browse term
  biological_process 18737
    developmental process 6897
      anatomical structure development 6372
        multicellular organism development 5440
          system development 4941
            immune system development 1129
              hematopoietic or lymphoid organ development 1061
                hemopoiesis 1012
                  leukocyte differentiation 634
                    mononuclear cell differentiation 485
                      lymphocyte differentiation 426
                        T cell differentiation 306
                          somatic diversification of T cell receptor genes 5
                            somatic diversification of T cell receptor genes by N region addition 0
                            somatic recombination of T cell receptor gene segments + 5
paths to the root