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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of vascular associated smooth muscle cell proliferation
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Accession:GO:1904707 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
Synonyms:exact_synonym: positive regulation of VSMC proliferation;   positive regulation of vascular smooth muscle cell proliferation;   up regulation of VSMC proliferation;   up regulation of vascular smooth muscle cell proliferation;   upregulation of VSMC proliferation;   upregulation of vascular smooth muscle cell proliferation
 narrow_synonym: activation of VSMC proliferation;   activation of vascular smooth muscle cell proliferation

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positive regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,376,288...65,385,398
Ensembl chr 2:65,376,310...65,385,918 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:24595849 RGD:11039416 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 acts_upstream_of_or_within ISO (PMID:19508861) MGI PMID:19508861 NCBI chr15:41,957,826...42,002,776 JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,944,463...45,108,832
Ensembl chr 9:44,941,460...45,027,275 		JBrowse link
G CALCRL calcitonin receptor like receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16537897) MGI
Ensembl		 PMID:16537897 GO_REF:0000107 NCBI chr10:72,884,271...72,986,916
Ensembl chr10:72,887,139...72,925,198 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chr 7:61,240,584...61,552,562 JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:16087782 RGD:150429767 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G DDX39B DExD-box helicase 39B ISO RGD PMID:23246467 RGD:10401139 NCBI chr17:40,445,258...40,457,379
Ensembl chr17:40,447,061...40,456,826 		JBrowse link
G DNMT1 DNA methyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G EDN1 endothelin 1 involved_in ISO PMID:28484848 BHF-UCL PMID:28484848 RGD:13601996 NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:57,145,080...57,233,757
Ensembl chr16:57,145,191...57,236,230 		JBrowse link
G FGF2 fibroblast growth factor 2 involved_in ISO (PMID:23263626) BHF-UCL PMID:23263626 NCBI chr 7:70,089,394...70,157,423 JBrowse link
G FGF9 fibroblast growth factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:1,779,126...1,811,427
Ensembl chr 3:1,779,192...1,812,784 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO RGD PMID:15292181 RGD:2289848 NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704 		JBrowse link
G FOXJ2 forkhead box J2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:8,101,982...8,125,764
Ensembl chr11:8,109,340...8,125,743 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 involved_in ISO PMID:28947594 BHF-UCL PMID:28947594 RGD:13524616 NCBI chr11:65,097,789...65,208,373
Ensembl chr11:65,197,385...65,208,379 		JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:28342807) ARUK-UCL
Ensembl		 PMID:28342807 GO_REF:0000107 NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chr22:11,623,394...11,646,464
Ensembl chr22:11,623,408...11,647,191 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr20:23,950,819...24,000,069
Ensembl chr20:23,954,384...23,999,072 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 PMID:27773680 RGD:13513992 RGD:13792711 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase ISO RGD PMID:24657469 RGD:11667099 NCBI chr 7:120,589,646...120,620,864
Ensembl chr 7:120,588,462...120,621,016 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:2,143,646...2,145,943
Ensembl chr13:2,144,313...2,145,485 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:23516544 RGD:10403075 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:107,207,363...107,232,237
Ensembl chr20:107,207,334...107,229,210 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:14638553 RGD:10412321 NCBI chr13:36,614,489...36,858,524
Ensembl chr13:36,615,633...36,858,601 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 ISO RGD PMID:35078016 RGD:155804282 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO RGD PMID:21498419 RGD:10412065 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G MEF2D myocyte enhancer factor 2D involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:7,358,647...7,394,068
Ensembl chr20:7,358,653...7,396,972 		JBrowse link
G MFN2 mitofusin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:119,787,700...119,818,455
Ensembl chr20:119,787,370...119,816,693 		JBrowse link
G MMP2 matrix metallopeptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004 		JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:16644864) MGI PMID:16644864 NCBI chr16:24,550,983...24,836,311
Ensembl chr16:24,550,977...24,836,307 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:23706097 PMID:34843718 RGD:329955360 RGD:329955579 NCBI chr  X:89,182,636...89,210,176
Ensembl chr  X:89,183,264...89,209,298 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 ISO RGD PMID:22508052 RGD:11073699 NCBI chr17:69,149,197...69,168,476
Ensembl chr17:69,147,937...69,161,045 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:39,568,085...39,611,704
Ensembl chr12:39,567,852...39,606,837 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:64,508,959...64,543,302
Ensembl chr 1:64,541,221...64,542,207 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:19901155 RGD:11533949 NCBI chr 1:68,530,037...68,679,413
Ensembl chr 1:68,529,571...68,617,092 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16644864) Ensembl
MGI		 PMID:16644864 GO_REF:0000107 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO in response to hypoxia RGD PMID:22527940 RGD:7242177 NCBI chr27:25,882,385...26,563,530
Ensembl chr27:26,465,499...26,564,582 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:9227431 RGD:150521729 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G TERT telomerase reverse transcriptase ISO RGD PMID:24376652 RGD:11038675 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:26808574) BHF-UCL PMID:26808574
G XBP1 X-box binding protein 1 involved_in
NOT|involved_in		 ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chr19:11,670,605...11,677,168 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19801
    cellular process 19323
      positive regulation of cellular process 6334
        positive regulation of cell population proliferation 1042
          positive regulation of smooth muscle cell proliferation 122
            positive regulation of vascular associated smooth muscle cell proliferation 46
Path 2
Term Annotations click to browse term
  biological_process 19801
    biological regulation 12150
      regulation of biological process 11755
        regulation of cellular process 11395
          regulation of cell population proliferation 1801
            regulation of smooth muscle cell proliferation 197
              regulation of vascular associated smooth muscle cell proliferation 80
                positive regulation of vascular associated smooth muscle cell proliferation 46
paths to the root