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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of smooth muscle cell proliferation
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Accession:GO:0048660 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
Synonyms:exact_synonym: regulation of SMC proliferation


show annotations for term's descendants           Sort by:
regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (MGI:3578606|PMID:15800000) RGD PMID:15800000 MGI:3578606 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISO
IEA
ISS		 (PMID:17122440)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17122440 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Nppc natriuretic peptide C IEP RGD PMID:11742834 RGD:70639 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISO
ISS		 (PMID:25852083)
GO_REF:0000024		 RGD
UniProt		 PMID:25852083 GO_REF:0000024 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Pde1a phosphodiesterase 1A IMP RGD PMID:16514069 RGD:2312521 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:21777465 RGD:5147661 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in ISO (PMID:17122440) RGD PMID:17122440 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:25852083) RGD PMID:25852083 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
negative regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 IMP RGD PMID:20703229 RGD:9685431 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:1857121|MGI:2183545 (MGI:1336863|PMID:10318840), (MGI:77583|PMID:8675666) RGD PMID:8675666 PMID:10318840 MGI:1336863 MGI:77583 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in ISO (PMID:22116621), (PMID:9614071) RGD PMID:9614071 PMID:22116621 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ang angiogenin involved_in ISO (PMID:10103013) RGD PMID:10103013 NCBI chr15:24,317,733...24,323,361 JBrowse link
G Apod apolipoprotein D involved_in ISO
ISS		 (PMID:14551159)
GO_REF:0000024		 RGD
UniProt		 PMID:14551159 GO_REF:0000024 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of ISO UniProtKB:P21274 (MGI:3795340|PMID:18382765) RGD PMID:18382765 MGI:3795340 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 UniProtKB:P01137 (PMID:18382765), (PMID:28467929)
GO_REF:0000107
UniProtKB:P37238 (MGI:3795340|PMID:18382765)		 RGD
Ensembl		 PMID:18382765 PMID:28467929 GO_REF:0000107 MGI:3795340 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO UniProtKB:P12643 (PMID:18382765) RGD PMID:18382765 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Cav1 caveolin 1 IMP RGD PMID:20828553 RGD:6849298 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Comt catechol-O-methyltransferase IMP RGD PMID:11071850 RGD:2289790 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (MGI:4821071|PMID:17122440) RGD PMID:17122440 MGI:4821071 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:22099601 RGD:8553200 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:22099601 RGD:8553200 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in IMP
ISO		 (PMID:17600318) RGD PMID:17600318 PMID:19885007 RGD:4145298 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 involved_in ISO
IEA		 (PMID:10766744)
GO_REF:0000107		 RGD
Ensembl		 PMID:10766744 GO_REF:0000107 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO (PMID:10766744) RGD PMID:10766744 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il15 interleukin 15 IMP RGD PMID:17667861 RGD:5013835 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Ilk integrin-linked kinase IMP reduction of wound healing in culture RGD PMID:18535176 RGD:2301740 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in IDA
IMP		 vascular smooth muscle cell
PMID:19531492		 RGD
UniProt		 PMID:17659301 PMID:19531492 RGD:1643591, RGD:8553301 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Mfn2 mitofusin 2 involved_in IDA PMID:15322553 UniProt PMID:15322553 RGD:1304351 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Ndrg4 NDRG family member 4 involved_in ISO
IEA		 (PMID:12755708)
GO_REF:0000107		 RGD
Ensembl		 PMID:12755708 GO_REF:0000107 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Nos3 nitric oxide synthase 3 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:1857229 (MGI:4462731|PMID:20554900)
GO_REF:0000107		 RGD
Ensembl		 PMID:20554900 PMID:12388111 PMID:14871555 GO_REF:0000107 MGI:4462731, RGD:628542, RGD:1580270 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:19104909 RGD:2324682 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:19104909 RGD:2324682 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IMP RGD PMID:21457229 RGD:7327141 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Ogn osteoglycin involved_in IMP PMID:21519924 UniProt PMID:21519924 RGD:8554796 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IMP cAMP-dependent RGD PMID:19783773 RGD:4107736 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:18585719 RGD:2324882 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of ISO
IGI		 UniProtKB:P01137 (PMID:18382765), (PMID:20622039), (PMID:28467929), (PMID:29182484), (PMID:31023188)
PMID:28867608
UniProtKB:P21274 (MGI:3795340|PMID:18382765), (MGI:5462034|PMID:21880694)		 RGD PMID:18382765 PMID:20622039 PMID:21880694 PMID:28467929 PMID:29182484 More... MGI:3795340 MGI:5462034, RGD:150521633 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha acts_upstream_of IMP
ISO		 (PMID:29182484) RGD PMID:29182484 PMID:19142226 RGD:10059645 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgir prostaglandin I2 receptor involved_in ISO
IBA		 (PMID:20622039)
(MGI:5437428|PMID:20622039)
PMID:21873635		 RGD PMID:20622039 PMID:21873635 MGI:5437428, RGD:13792537 NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:16648138 RGD:1626091 NCBI chr 9:105,456,425...105,492,711
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
G Sf1 splicing factor 1 IMP RGD PMID:11748220 RGD:632653 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:16816117) RGD PMID:16816117 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tp53 tumor protein p53 IMP RGD PMID:17659301 RGD:1643591 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (PMID:17452330) RGD PMID:17452330 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Vip vasoactive intestinal peptide involved_in IMP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:20452385 PMID:21873635 RGD:5685633, RGD:13792537 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IMP RGD PMID:20452385 RGD:5685633 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
negative regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:12070119)		 UniProt
RGD		 PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agt angiotensinogen acts_upstream_of_or_within ISO MGI:2183545 (MGI:77583|PMID:8675666) RGD PMID:8675666 MGI:77583 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Apln apelin involved_in ISO (PMID:23263626) RGD PMID:23263626 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Cav1 caveolin 1 IMP RGD PMID:29069575 RGD:151347449 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:25681685) RGD PMID:25681685 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B involved_in ISO
IMP		 (PMID:19088079) RGD PMID:19088079 PMID:28854428 RGD:152025191 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cnn1 calponin 1 involved_in ISO UniProtKB:P17861-2 (PMID:26315405) RGD PMID:26315405 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Drd4 dopamine receptor D4 IDA RGD PMID:24888351 RGD:13506962 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 involved_in ISO (MGI:5584046|PMID:23636094) RGD PMID:23636094 MGI:5584046 NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414 		JBrowse link
G Gna12 G protein subunit alpha 12 acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gna13 G protein subunit alpha 13 acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA		 (PMID:23840305)
GO_REF:0000107		 RGD
Ensembl		 PMID:23840305 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:24321768 RGD:10401938 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hmox1 heme oxygenase 1 IMP RGD PMID:22709785 RGD:10755720 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il10 interleukin 10 involved_in ISO UniProtKB:P06804 (MGI:5796069|PMID:26808574) RGD PMID:26808574 MGI:5796069 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO
IEA		 RNAcentral:URS000001C659_9606|RNAcentral:URS000075BB59_9606 (PMID:26184978), (PMID:28799067)
GO_REF:0000107		 RGD
Ensembl		 PMID:26184978 PMID:28799067 GO_REF:0000107 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28478070 RGD:12910733 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:21051663), (PMID:26166810) RGD PMID:21051663 PMID:26166810 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir125a microRNA 125a IDA RGD PMID:29700287 RGD:26884455 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir133a1 microRNA 133a-1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir137 microRNA 137 involved_in ISO (PMID:29016699) RGD PMID:29016699 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir140 microRNA 140 involved_in ISO (PMID:27021683), (PMID:27214554) RGD PMID:27021683 PMID:27214554 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir185 microRNA 185 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir1b microRNA 1b involved_in ISO (PMID:21051663), (PMID:26166810) RGD PMID:21051663 PMID:26166810 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:27927633) RGD PMID:27927633 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir223 microRNA 223 involved_in IDA
ISO		 (PMID:27121304) RGD PMID:27121304 PMID:30246291 RGD:25823198 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir322 microRNA 322 involved_in ISO RNAcentral:URS00000F6E49_9606 (PMID:23263626) RGD PMID:23263626 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:24792364), (PMID:26493107), (PMID:27302634) RGD PMID:24792364 PMID:26493107 PMID:27302634 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir3582 microRNA 3582 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr18:1,885,063...1,885,180
Ensembl chr18:1,885,063...1,885,180 		JBrowse link
G Mir503 microRNA 503 involved_in ISO RNAcentral:URS00000F0F49_9606 (PMID:21220732), (PMID:23263626) RGD PMID:21220732 PMID:23263626 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir665 microRNA 665 involved_in ISO (PMID:29118903) RGD PMID:29118903 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir96 microRNA 96 involved_in ISO (PMID:25871906) RGD PMID:25871906 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Myocd myocardin involved_in IEA
ISO		 GO_REF:0000107
(MGI:5644147|PMID:23825366)		 Ensembl
RGD		 PMID:23825366 GO_REF:0000107 MGI:5644147 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Ndrg2 NDRG family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3655783|PMID:16520977)
GO_REF:0000107		 RGD
Ensembl		 PMID:16520977 GO_REF:0000107 MGI:3655783 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Park7 Parkinsonism associated deglycase IDA RGD PMID:29069575 RGD:151347449 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdcd4 programmed cell death 4 involved_in ISO (PMID:28522568) RGD PMID:28522568 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:24960162), (PMID:28522568) RGD PMID:24960162 PMID:28522568 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:25447536) RGD PMID:25447536 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:26208095) RGD PMID:26208095 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rbm10 RNA binding motif protein 10 acts_upstream_of_or_within ISO MGI:87964 (MGI:4367529|PMID:19508861) RGD PMID:19508861 MGI:4367529 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 IDA RGD PMID:18207159 RGD:13524535 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within IMP PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 acts_upstream_of_or_within IGI PMID:29453251 MGI PMID:29453251 RGD:42721986 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:27021683) RGD PMID:27021683 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tafa5 TAFA chemokine like family member 5 acts_upstream_of_or_within ISO
IDA
IGI		 (MGI:6380922|PMID:29453251)
(PMID:29453251)		 RGD PMID:29453251 PMID:29453251 PMID:29453251 MGI:6380922, RGD:42721986, RGD:42721986 NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IMP RGD PMID:28854428 RGD:152025191 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO (PMID:21817107) RGD PMID:21817107 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
positive regulation of smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 IMP RGD PMID:18636120 RGD:2301071 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:16368901 PMID:23212096 RGD:1625344, RGD:7244285 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aif1 allograft inflammatory factor 1 involved_in IMP
ISS
ISO		 GO_REF:0000024
(PMID:15117732), (PMID:22116621)		 UniProt
RGD		 PMID:15117732 PMID:22116621 PMID:18779232 GO_REF:0000024, RGD:2313013 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 IMP RGD PMID:16648138 RGD:1626091 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:21321938) RGD PMID:21321938 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:16199435 RGD:5509792 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:10706139), (PMID:17600318)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:10706139 PMID:17600318 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:22089112 RGD:7411627 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:21297082) RGD PMID:21297082 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:23807044 RGD:10003107 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Cdh13 cadherin 13 involved_in ISO (PMID:15364621) RGD PMID:15364621 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in IDA PMID:12729461 RGD
ARUK-UCL		 PMID:17182651 PMID:12729461 RGD:4891893, RGD:13673777 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cyba cytochrome b-245 alpha chain IMP RGD PMID:15036821 RGD:8693734 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:10393673) RGD PMID:10393673 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:15486316 RGD:1581908 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 IMP RGD PMID:23973488 RGD:10395311 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elane elastase, neutrophil expressed involved_in ISO (PMID:15010259) RGD PMID:15010259 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Ereg epiregulin involved_in IMP
IDA		 PMID:9990076 RGD
UniProt		 PMID:14570897 PMID:9990076 RGD:2316285, RGD:632743 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:9854551 RGD:8655666 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IDA RGD PMID:12062723 RGD:1582498 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:24023716) RGD PMID:24023716 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Gnaq G protein subunit alpha q IMP RGD PMID:14981460 RGD:1598489 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:21557011 RGD:10045551 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in ISO (MGI:3690187|PMID:1840698) RGD PMID:1840698 MGI:3690187 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in IGI PMID:28867608 BHF-UCL PMID:28867608 RGD:150521633 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in ISO
ISS		 UniProtKB:Q61982 (PMID:19855400)
GO_REF:0000024		 RGD
UniProt		 PMID:19855400 GO_REF:0000024 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:16489407 RGD:1626319 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:18413661 RGD:5508694 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:17600318) RGD PMID:17600318 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Id2 inhibitor of DNA binding 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4412240|PMID:18474814)		 UniProt
RGD		 PMID:18474814 GO_REF:0000024 MGI:4412240 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:10766744), (PMID:16942485) RGD PMID:10766744 PMID:16942485 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IMP RGD PMID:21854769 RGD:10046007 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il13 interleukin 13 IDA RGD PMID:20045483 RGD:4145470 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:21321938)		 Ensembl
RGD		 PMID:21321938 PMID:22636674 GO_REF:0000107, RGD:8655954 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:10510402) RGD PMID:10510402 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor involved_in ISO
IEA		 (PMID:10510402)
GO_REF:0000107		 RGD
Ensembl		 PMID:10510402 GO_REF:0000107 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IMP RGD PMID:15890643 RGD:1579817 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Itga2 integrin subunit alpha 2 IMP RGD PMID:19239475 RGD:2307394 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:19723557 RGD:4892625 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA pulmonary artery smooth muscle cells RGD PMID:11571252 RGD:2290591 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mmp2 matrix metallopeptidase 2 acts_upstream_of_or_within ISO (MGI:3714217|PMID:17561096) RGD PMID:17561096 MGI:3714217 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase IMP RGD PMID:10026172 RGD:2308868 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19589861 RGD:10003166 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myb MYB proto-oncogene, transcription factor IMP RGD PMID:8665409 RGD:11532682 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:8113414 RGD:10059612 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IMP RGD PMID:15890643 RGD:1579817 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase IMP RGD PMID:18952695 RGD:2311234 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Notch3 notch receptor 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4367619|PMID:19855400)		 Ensembl
RGD		 PMID:19855400 GO_REF:0000107 MGI:4367619 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in IMP PMID:10485709 BHF-UCL PMID:10485709 RGD:633401 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:12710532 RGD:1625500 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5297326|PMID:16945922)		 UniProt
RGD		 PMID:16945922 GO_REF:0000024 MGI:5297326 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Orc1 origin recognition complex, subunit 1 IMP RGD PMID:18499104 RGD:9588277 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Pde4d phosphodiesterase 4D IMP RGD PMID:21776361 RGD:7327157 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IMP
ISO
ISS		 (MGI:1338343|PMID:10375497), (MGI:6827319|PMID:28867608)
GO_REF:0000024
(PMID:21321938)		 RGD
ARUK-UCL		 PMID:10375497 PMID:21321938 PMID:28867608 PMID:17449016 GO_REF:0000024 MGI:1338343 MGI:6827319, RGD:2292197 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfd platelet derived growth factor D IDA RGD PMID:15752751 RGD:9854640 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
ISS		 (PMID:21679854)
(MGI:1338343|PMID:10375497)
GO_REF:0000024		 RGD
UniProt		 PMID:10375497 PMID:21679854 GO_REF:0000024 MGI:1338343 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phb1 prohibitin 1 involved_in IMP PMID:32173312 UniProt PMID:32173312 RGD:30309944 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha IMP RGD PMID:25908763 RGD:13207417 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Prkca protein kinase C, alpha IMP RGD PMID:17908462 RGD:2292473 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:8216700 RGD:10043166 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17645304 RGD:1642591 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IMP RGD PMID:15208331 RGD:2292605 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family IMP vascular smooth muscle cells RGD PMID:21125971 RGD:4892313 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region IMP RGD PMID:15247148 RGD:2306423 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Retn resistin IMP RGD PMID:20795947 RGD:7207234 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IMP RGD PMID:16148030 RGD:1643021 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:11557736 RGD:1581747 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (MGI:4453296|PMID:18436805) RGD PMID:18436805 MGI:4453296 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Shc1 SHC adaptor protein 1 IMP RGD PMID:12837289 RGD:1304398 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Skp2 S-phase kinase associated protein 2 IMP RGD PMID:19878790 RGD:2315048 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3714217|PMID:17561096)		 Ensembl
RGD		 PMID:17561096 GO_REF:0000107 MGI:3714217 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:17293493 RGD:1600088 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IMP RGD PMID:16527988 RGD:1601384 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Sulf1 sulfatase 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:28467929), (PMID:31023188) RGD PMID:28467929 PMID:31023188 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:11178962 RGD:1601605 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgm2 transglutaminase 2 IDA RGD PMID:14970202 RGD:1579990 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:24615654) RGD PMID:24615654 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5462034|PMID:21880694)
GO_REF:0000107		 RGD
Ensembl		 PMID:21880694 GO_REF:0000107 MGI:5462034 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:16518841) RGD PMID:16518841 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf6 TNF receptor associated factor 6 IMP RGD PMID:15890643 RGD:1579817 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Vegfa vascular endothelial growth factor A IMP RGD PMID:14693680 RGD:1580560 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zfp143 zinc finger protein 143 IMP RGD PMID:21352097 RGD:9743924 NCBI chr 1:164,109,041...164,144,902
Ensembl chr 1:164,109,116...164,144,902 		JBrowse link
positive regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 involved_in ISO
IEA		 RNAcentral:URS00003A19A3_9606 (PMID:28890348)
GO_REF:0000107		 RGD
Ensembl		 PMID:28890348 GO_REF:0000107 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Agt angiotensinogen IDA RGD PMID:24595849 RGD:11039416 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a acts_upstream_of_or_within ISO MGI:1857147 (MGI:4367529|PMID:19508861) RGD PMID:19508861 MGI:4367529 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18667463)
(MGI:3810850|PMID:18667463)		 RGD PMID:18667463 MGI:3810850 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Calcrl calcitonin receptor like receptor acts_upstream_of_or_within ISO (MGI:3619781|PMID:16537897) RGD PMID:16537897 MGI:3619781 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:17267544 RGD:2303063 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:16087782 RGD:150429767 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:23246467 RGD:10401139 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA		 (PMID:27021683)
GO_REF:0000107		 RGD
Ensembl		 PMID:27021683 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Edn1 endothelin 1 involved_in IDA PMID:28484848 BHF-UCL PMID:28484848 RGD:13601996 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:26315405) RGD PMID:26315405 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO UniProtKB:Q9ULZ1 (PMID:23263626) RGD PMID:23263626 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in ISO
IMP		 RNAcentral:URS0000355E82_9606 (PMID:29118903)
PMID:28259995		 RGD PMID:29118903 PMID:28259995 RGD:13601993 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IMP RGD PMID:15292181 RGD:2289848 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) RGD PMID:24792364 NCBI chr 4:156,047,043...156,073,540
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in IMP PMID:28947594 BHF-UCL PMID:28947594 RGD:13524616 NCBI chr 7:52,711,255...52,792,758
Ensembl chr 7:52,711,257...52,792,743 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of ISO (PMID:28342807) RGD PMID:28342807 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:27773680 PMID:24018045 RGD:13513992, RGD:13792711 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase IMP RGD PMID:24657469 RGD:11667099 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (PMID:25871906) RGD PMID:25871906 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 (PMID:26166810)
GO_REF:0000107		 RGD
Ensembl		 PMID:26166810 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO RNAcentral:URS00001E3523_9606 (PMID:29016699) RGD PMID:29016699 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:23516544 RGD:10403075 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:28701355) RGD PMID:28701355 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:28257760) RGD PMID:28257760 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IMP RGD PMID:14638553 RGD:10412321 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IMP RGD PMID:35078016 RGD:155804282 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP RGD PMID:21498419 RGD:10412065 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mef2d myocyte enhancer factor 2D involved_in ISO
IEA		 RNAcentral:URS0000355E82_9606 (PMID:29118903)
GO_REF:0000107		 RGD
Ensembl		 PMID:29118903 GO_REF:0000107 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Mfn2 mitofusin 2 involved_in ISO (PMID:27640178) RGD PMID:27640178 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir125a microRNA 125a IMP RGD PMID:30156956 RGD:26884369 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir130a microRNA 130a involved_in ISO (PMID:24960162), (PMID:25681685) RGD PMID:24960162 PMID:25681685 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir135b microRNA 135b involved_in ISO (PMID:26184978) RGD PMID:26184978 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:30779466) RGD PMID:30779466 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:22161164), (PMID:27640178) RGD PMID:22161164 PMID:27640178 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22450430), (PMID:25447536) RGD PMID:22450430 PMID:25447536 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:20693317), (PMID:21817107), (PMID:22034194), (PMID:26208095), (PMID:28522568) RGD PMID:20693317 PMID:21817107 PMID:22034194 PMID:26208095 PMID:28522568 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir214 microRNA 214 involved_in ISO (PMID:27144530), (PMID:28684904) RGD PMID:27144530 PMID:28684904 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 IMP RGD PMID:28854428 RGD:152025191 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:20857419) RGD PMID:20857419 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir301a microRNA 301a involved_in ISO (PMID:25681685) RGD PMID:25681685 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
G Mir448 microRNA 448 involved_in ISO (PMID:28799067) RGD PMID:28799067 NCBI chr  X:110,829,918...110,830,029
Ensembl chr  X:110,829,918...110,830,029 		JBrowse link
G Mir499a microRNA 499a involved_in ISO (PMID:26184978) RGD PMID:26184978 NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533 		JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18667463)		 Ensembl
RGD		 PMID:18667463 GO_REF:0000107 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18667463)		 Ensembl
RGD		 PMID:18667463 GO_REF:0000107 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:97528 (MGI:3629249|PMID:16644864)
GO_REF:0000107		 RGD
Ensembl		 PMID:16644864 GO_REF:0000107 MGI:3629249 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 IMP RGD PMID:22508052 RGD:11073699 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in ISO RNAcentral:URS000075DB2F_9606 (PMID:23554459) RGD PMID:23554459 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:19901155 RGD:11533949 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97306 (MGI:3629249|PMID:16644864)
(PMID:12070119), (PMID:19088079), (PMID:23554459)		 Ensembl
RGD		 PMID:12070119 PMID:16644864 PMID:19088079 PMID:23554459 GO_REF:0000107 MGI:3629249 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP in response to hypoxia RGD PMID:22527940 RGD:7242177 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:9227431 RGD:150521729 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tert telomerase reverse transcriptase IMP RGD PMID:24376652 RGD:11038675 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:5796069|PMID:26808574) RGD PMID:26808574 MGI:5796069 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in
NOT|involved_in		 ISO (PMID:26315405) RGD PMID:26315405 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857556 (MGI:3587974|PMID:15849236)
GO_REF:0000107		 RGD
Ensembl		 PMID:15849236 GO_REF:0000107 MGI:3587974 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    cellular process 18161
      cell population proliferation 2273
        regulation of cell population proliferation 1917
          regulation of smooth muscle cell proliferation 221
            negative regulation of smooth muscle cell proliferation + 84
            positive regulation of smooth muscle cell proliferation + 136
            regulation of vascular associated smooth muscle cell proliferation + 104
Path 2
Term Annotations click to browse term
  biological_process 19748
    biological regulation 13456
      regulation of biological process 13044
        regulation of cellular process 12253
          regulation of cell population proliferation 1917
            regulation of smooth muscle cell proliferation 221
              negative regulation of smooth muscle cell proliferation + 84
              positive regulation of smooth muscle cell proliferation + 136
              regulation of vascular associated smooth muscle cell proliferation + 104
paths to the root