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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of tumor necrosis factor-mediated signaling pathway
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Accession:GO:1903265 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
Synonyms:exact_synonym: positive regulation of tumor necrosis factor-mediated signalling pathway;   up regulation of tumor necrosis factor-mediated signaling pathway;   up regulation of tumor necrosis factor-mediated signalling pathway;   upregulation of tumor necrosis factor-mediated signaling pathway;   upregulation of tumor necrosis factor-mediated signalling pathway
 narrow_synonym: activation of TNF-alpha-mediated signaling pathway;   activation of tumor necrosis factor alpha-mediated signaling pathway;   activation of tumor necrosis factor-mediated signaling pathway;   activation of tumor necrosis factor-mediated signalling pathway;   positive regulation of TNF-alpha-mediated signaling pathway;   positive regulation of tumor necrosis factor alpha-mediated signaling pathway;   up regulation of TNF-alpha-mediated signaling pathway;   up regulation of tumor necrosis factor alpha-mediated signaling pathway;   upregulation of TNF-alpha-mediated signaling pathway;   upregulation of tumor necrosis factor alpha-mediated signaling pathway
 related_synonym: activation of adipocytokine signaling pathway;   positive regulation of adipocytokine signaling pathway;   up regulation of adipocytokine signaling pathway;   upregulation of adipocytokine signaling pathway


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positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase involved_in ISO (PMID:16920334) UniProt PMID:16920334 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CPNE1 copine 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:38,956,489...38,997,189
Ensembl chr17:38,956,673...38,964,890 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,912...87,390,288 		JBrowse link
G LOC100522887 caspase-13 involved_in ISO (PMID:16920334) UniProt PMID:16920334 NCBI chr 9:35,167,567...35,185,791 JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:33,384,034...33,397,637
Ensembl chr 9:33,384,033...33,396,947 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:1,841,143...1,880,705
Ensembl chr 7:1,841,239...1,880,699 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107
G TRIM32 tripartite motif containing 32 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr 1:257,051,421...257,066,911
Ensembl chr 1:257,054,228...257,066,909 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:30,887,784...30,961,685
Ensembl chr 8:30,887,830...30,963,762 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17805
    positive regulation of biological process 6503
      positive regulation of response to stimulus 2404
        positive regulation of response to cytokine stimulus 61
          positive regulation of cytokine-mediated signaling pathway 54
            positive regulation of tumor necrosis factor-mediated signaling pathway 11
Path 2
Term Annotations click to browse term
  biological_process 17805
    biological regulation 12904
      regulation of biological process 12537
        signaling 7507
          signal transduction 6963
            cell surface receptor signaling pathway 2809
              cytokine-mediated signaling pathway 498
                regulation of cytokine-mediated signaling pathway 158
                  positive regulation of cytokine-mediated signaling pathway 54
                    positive regulation of tumor necrosis factor-mediated signaling pathway 11
paths to the root