UBE2K (ubiquitin conjugating enzyme E2 K)

Gene: UBE2K (ubiquitin conjugating enzyme E2 K) Sus scrofa

Analyze

Symbol:

UBE2K

Name:

ubiquitin conjugating enzyme E2 K

RGD ID:

14047576

Description:

ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transferase activity (inferred); INVOLVED IN intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Hyperglycinemia, Lactic Acidosis, and Seizures (ortholog); FOUND IN cytoplasm (inferred); filopodium tip (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

UBC1; ubiquitin-conjugating enzyme E2 K

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	30,887,830 - 30,963,762 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	30,887,784 - 30,961,685 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	32,580,147 - 32,654,102 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hyperglycinemia, Lactic Acidosis, and Seizures (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to interferon-beta (IEA)

free ubiquitin chain polymerization (IEA)

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ISO)

positive regulation of peptidyl-threonine phosphorylation (IEA)

positive regulation of tumor necrosis factor-mediated signaling pathway (IEA)

positive regulation of type I interferon-mediated signaling pathway (IEA)

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA,IEA)

protein K48-linked ubiquitination (IEA)

protein polyubiquitination (IBA,IEA)

regulation of proteasomal ubiquitin-dependent protein catabolic process (IEA,ISO)

Cellular Component

cytoplasm (IEA)

filopodium tip (IEA)

nucleus (IBA,IEA)

Molecular Function

ATP binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

transferase activity (IEA)

ubiquitin conjugating enzyme activity (IBA,IEA)

ubiquitin protein ligase binding (IEA)

ubiquitin-protein transferase activity (IEA)

ubiquitin-ubiquitin ligase activity (IEA)

References

Additional References at PubMed

PMID:14681463	PMID:15679890	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

UBE2K
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	30,887,830 - 30,963,762 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	30,887,784 - 30,961,685 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	32,580,147 - 32,654,102 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBE2K
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	39,698,136 - 39,782,792 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	39,698,109 - 39,782,792 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	39,699,756 - 39,784,412 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	39,376,266 - 39,457,977 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	39,522,436 - 39,604,148	NCBI
Celera	4	40,137,995 - 40,223,124 (+)	NCBI		Celera
Cytogenetic Map	4	p14	NCBI
HuRef	4	39,024,547 - 39,109,580 (+)	NCBI		HuRef
CHM1_1	4	39,699,339 - 39,784,070 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	39,667,902 - 39,752,430 (+)	NCBI		T2T-CHM13v2.0

Ube2k
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	65,694,588 - 65,756,332 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	65,694,576 - 65,756,331 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	65,537,245 - 65,598,989 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	65,537,233 - 65,598,988 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	65,928,500 - 65,990,228 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	65,816,406 - 65,878,063 (+)	NCBI		MGSCv36	mm8
Celera	5	62,815,933 - 62,878,205 (+)	NCBI		Celera
Cytogenetic Map	5	C3.1	NCBI
cM Map	5	33.72	NCBI

Ube2k
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	43,011,681 - 43,077,825 (-)	NCBI		GRCr8
mRatBN7.2	14	42,658,016 - 42,718,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	42,658,016 - 42,718,630 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	43,011,647 - 43,072,105 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	44,311,686 - 44,372,016 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	42,791,658 - 42,852,126 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	44,289,247 - 44,348,691 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	44,289,247 - 44,348,691 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	44,108,859 - 44,168,755 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	45,349,287 - 45,411,823 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	45,354,342 - 45,414,183 (-)	NCBI
Celera	14	41,809,022 - 41,869,333 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

Ube2k
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955443	7,618,379 - 7,656,305 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955443	7,618,379 - 7,655,542 (-)	NCBI	ChiLan1.0	ChiLan1.0

UBE2K
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	39,886,781 - 39,972,600 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	40,079,239 - 40,164,593 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	34,026,942 - 34,111,923 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	39,877,966 - 39,960,402 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	39,877,966 - 39,960,397 (+)	Ensembl	panpan1.1		panPan2

UBE2K
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	72,713,035 - 72,780,199 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	72,717,236 - 72,780,210 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	75,259,911 - 75,327,198 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	73,485,595 - 73,553,473 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	73,485,593 - 73,553,418 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	72,752,394 - 72,820,149 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	72,898,341 - 72,966,163 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	73,284,799 - 73,352,656 (-)	NCBI		UU_Cfam_GSD_1.0

Ube2k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	38,975,456 - 39,053,214 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	7,244,967 - 7,323,266 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	7,244,972 - 7,323,263 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBE2K
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	10,535,091 - 10,618,659 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	10,539,402 - 10,618,573 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	56,921,431 - 57,007,501 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ube2k
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	27,205,034 - 27,276,884 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624761	27,205,034 - 27,277,016 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in UBE2K
1673 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium	10	2	3	5	2	23	2	3	3
Low		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001078671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013978606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021100521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK231664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY609551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ972952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP089694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01046267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000037743 ⟹ ENSSSCP00000047545

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	30,887,835 - 30,961,675 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000043661 ⟹ ENSSSCP00000040258

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	30,913,159 - 30,961,679 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000047460 ⟹ ENSSSCP00000036456

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	30,887,830 - 30,963,762 (+)	Ensembl

RefSeq Acc Id:

NM_001078671 ⟹ NP_001072139

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	8	30,887,994 - 30,959,314 (+)	NCBI

Sequence:

show sequence

ATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTGCTGAAGAGCGAGGAGA
CGAGCAAAAATCAAATTAAAGTAGATCTTGTAGATGAGAATTTTACAGAATTAAGAGGAGAAAT
AGCAGGACCTCCAGACACACCATATGAAGGAGGAAGATATCAACTAGAGATTAAAATACCAGAA
ACATATCCATTTAATCCCCCTAAGGTCCGGTTTATCACAAAAATATGGCATCCTAATATTAGTT
CCGTCACAGGGGCTATTTGTTTGGATATCCTGAAAGATCAATGGGCAGCAGCAATGACTCTGCG
CACAGTATTATTGTCATTGCAAGCACTACTGGCAGCTGCAGAACCAGATGATCCACAAGATGCA
GTAGTAGCGAATCAGTACAAACAAAATCCTGAAATGTTCAAACAAACAGCTCGACTTTGGGCAC
ATGTGTATGCTGGAGCACCAGTTTCTAGTCCAGAATACACCAAAAAAATAGAAAACTTATGTGC
TATGGGCTTTGATAGGAATGCGGTAATAGTGGCCTTGTCTTCAAAATCATGGGATGTAGAGACT
GCAACAGAATTGCTTCTGAGTAACTGA

hide sequence

RefSeq Acc Id:

XM_013978606 ⟹ XP_013834060

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	8	30,887,784 - 30,961,685 (+)	NCBI

Sequence:

show sequence

CGCAGGCGCGGACCTGGCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGAGAG
CGCGGCGGCCGGAGTGGCAGTGGCAGCGTTCGTGTGCTCTGGTGTGAATCGCCGAGGGAGGAGG
CGGTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAA
TCAGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGG
TGCTGAAGAGCGAGGAGGGCAGCAGCAATGACTCTGCGCACAGTATTATTGTCATTGCAAGCAC
TACTGGCAGCTGCAGAACCAGATGATCCACAAGATGCAGTAGTAGCGAATCAGTACAAACAAAA
TCCTGAAATGTTCAAACAAACAGCTCGACTTTGGGCACATGTGTATGCTGGAGCACCAGTTTCT
AGTCCAGAATACACCAAAAAAATAGAAAACTTATGTGCTATGGGCTTTGATAGGAATGCGGTAA
TAGTGGCCTTGTCTTCAAAATCATGGGATGTAGAGACTGCAACAGAATTGCTTCTGAGTAACTG
AGACATAGAGCTGCTGATATAGTCAAGCTTGCCCCTTCTTGAGGAGCATCAATATCTGTTATTT
TTAGGATTCTGCATAGATATCTTTTAAACTGGCATTCTTGCCTAATGATGTTATCTAGGCACCA
TTGGAGACTGAAAAAAAAATTTCATGCTCTGTAAATAAAGCTAATTAAACGTCTGTGTAAATTT
AAAAAGGGGAAATACTTTTTTTCTTACTTAATAGTGTAAAAATTATTTGAGCTAAGCTAAAACC
ATGGAAAAAACATGCTACTTTAGTGTTTAGCAGTGTACCAAGACTAAGCAAGAATTTGCTTCAG
GATTTCATTGAATAATTAAGATAATATTTTGAGTGTGTCAGGGCCATTCAAATTGTTGGTGTTG
CATCACAGCTACCTTAACTGTTTTTTAACATGGATCCTCTGTGCCTGTGAATTTACTTGCATGC
TTGTACTTGACTTCTTAGGATGGGTAGCTGAAAAGACCACCATTTTAAGCATTTGAGAATTCTT
AAATATGCGTTTTATCCAGAATTGAAGATGGTGACCTATTCAGAGCCTTTTTGTCCTTGTCAAT
AGACTGGGACACCATATCTATTTTTTCCTTCTTAACCACCCACAGCTAATATTCTAATAGTAAA
TTTTTCTTTATTTGGTGGGGAAATATGCAGAGGGATAGTATCCCTTGCTCCATTTTTAGGATGT
CCATTTGGAATGTTCTGTCACAGATCTTCACTCTTAAAACTTTCCTATGTAAGTAAATAATAAT
GTAAAAATGGAGCTGCCAGTTTTCTTTCTTTTACAAAAACAGTAAGTACTCGATGTTGCAGTAT
TTCCAGATTTAATGAAAGAACACAACTTAGTTTTTCAGTGAATTTAACATCTTTCTATTTTTAA
ACTGATGAAATTTTTCTTTGGTAACTTGCAAGGATGAAATCACCTGTTTGCAGTTTTTTTAAGC
CTAATTTTGGCTTTATGGAGATTGCTTTATTGGTTACTTTAAAAGTCACCCTTGCTTGCATTTC
CCCCTATTTGACACATGAAAGCTGTGTTGGGTGTTTTACTGTACATACTTCAAATGCACATAGG
AATAGAAGTGTGTTATAAATCTAGCTTTCTTTATGATGTTTCTGATAATATTGAGAATTGAAAA
CTTTACCTTCTCTTGTACATAGTCAGACTTTCTATACGTATTAAAGTTACATTTCATTCTAAGT
TCAAAAGTTTGAAAATTATTAGTTTTGCAAGCTCAAACACTAATGTGACCATTTTATGAAGGGT
GAAATGGATTTGTGTAGACAGTTCTAAACATAGAAATACAGTTACTAAATATTCAGGACCAATG
CGAAATAACAAGAATGTAATGGAATTAGAATGAATTAAAGTAAGGTTGTATATTGAAAGTCATA
TTATAAAAGGTTTGCTTTTTTCAAGTGTTATTTATCTGAAATTATAATGGTTAAGTGTTTGGAA
ACAAGTTTTGAACCATAAATTCAGCATAATTTCATTTGACTTCTCATTAATCTTAGAAGCAATA
AAAGAACCATTATTAAATATGTTGTAATGTTAAGATGTGAAGGTTCTTCCAAAAACTTGTAAGG
CTTTCCTAATCAATAGTAAACTCTTGTAGTTGATATTATTGCATACTAAATACAAGTTGCTGTT
CTTTTCCCCTATATATTTGCTTAAGTATAAATTTCTTTATACAATCATTTCCTTTAATTGTTGT
AATTTAGTTACTTTCTAAAGATGCCAAAGGAAACAGATTTTTTTCTTTATTTATTTTAAATAGT
TAAAACCCTGTACTTTTCTTTATGTTTTTGAAGTAAGGTTGAAATTGTGTGAAAATGTGGACAG
CTTTGTTCCATTGTTGATTAGAATTAATTTTTTTTTTTTTAGTGGAGGGTGGCATGGTAATATT
AGTAATATTTGGATTATTTTAAATATCAAACACTTCTACCCAGTTTACTATTTGCCTATAGTAA
TGTTATCAGGGTATATTTAATTGTCCTGTGGTTTGACAGATGAGAGAGAACTCAGAAGTTACTA
AAGGTCAAGCATTACATACTTTGCTCTTGGAGGCAGCTATACCTTCCTTGCCTGTGACTTTTAT
GCACATTAGCCCCTTAGGCTATACTCATCTAACTACAGTTTAACATCACCAGTGCCCAGGAAAT
GGAAAAGTACAATATTTGGTATGAGAGGTTTTCCATAGGATTTTTCATGTCAAAAATTTACCTC
GTTTACATTTAATGTATCATCTCTTTCCTTTCTGGTACATTTCCCACTGTCATCTTCTGTTGTT
TTTTTCATATTTTTCTACAGGTAGATTTATTTCCACAAACATAGAAATAAAGACAATTGCTTTT
TTTC

hide sequence

RefSeq Acc Id:

XM_021100521 ⟹ XP_020956180

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	8	30,887,786 - 30,961,685 (+)	NCBI

Sequence:

show sequence

CAGGCGCGGACCTGGCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCCACACTGAGGAGAGCG
CGGCGGCCGGAGTGGCAGTGGCAGCGTTCGTGTGCTCTGGTGTGAATCGCCGAGGGAGGAGGCG
GTGGAGGAAGAGGTGGCGGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATC
AGCTGCGGGCGGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGAGGTG
CTGAAGAGCGAGGAGGAGGAAGATATCAACTAGAGATTAAAATACCAGAAACATATCCATTTAA
TCCCCCTAAGGTCCGGTTTATCACAAAAATATGGCATCCTAATATTAGTTCCGTCACAGGGGCT
ATTTGTTTGGATATCCTGAAAGATCAATGGGCAGCAGCAATGACTCTGCGCACAGTATTATTGT
CATTGCAAGCACTACTGGCAGCTGCAGAACCAGATGATCCACAAGATGCAGTAGTAGCGAATCA
GTACAAACAAAATCCTGAAATGTTCAAACAAACAGCTCGACTTTGGGCACATGTGTATGCTGGA
GCACCAGTTTCTAGTCCAGAATACACCAAAAAAATAGAAAACTTATGTGCTATGGGCTTTGATA
GGAATGCGGTAATAGTGGCCTTGTCTTCAAAATCATGGGATGTAGAGACTGCAACAGAATTGCT
TCTGAGTAACTGAGACATAGAGCTGCTGATATAGTCAAGCTTGCCCCTTCTTGAGGAGCATCAA
TATCTGTTATTTTTAGGATTCTGCATAGATATCTTTTAAACTGGCATTCTTGCCTAATGATGTT
ATCTAGGCACCATTGGAGACTGAAAAAAAAATTTCATGCTCTGTAAATAAAGCTAATTAAACGT
CTGTGTAAATTTAAAAAGGGGAAATACTTTTTTTCTTACTTAATAGTGTAAAAATTATTTGAGC
TAAGCTAAAACCATGGAAAAAACATGCTACTTTAGTGTTTAGCAGTGTACCAAGACTAAGCAAG
AATTTGCTTCAGGATTTCATTGAATAATTAAGATAATATTTTGAGTGTGTCAGGGCCATTCAAA
TTGTTGGTGTTGCATCACAGCTACCTTAACTGTTTTTTAACATGGATCCTCTGTGCCTGTGAAT
TTACTTGCATGCTTGTACTTGACTTCTTAGGATGGGTAGCTGAAAAGACCACCATTTTAAGCAT
TTGAGAATTCTTAAATATGCGTTTTATCCAGAATTGAAGATGGTGACCTATTCAGAGCCTTTTT
GTCCTTGTCAATAGACTGGGACACCATATCTATTTTTTCCTTCTTAACCACCCACAGCTAATAT
TCTAATAGTAAATTTTTCTTTATTTGGTGGGGAAATATGCAGAGGGATAGTATCCCTTGCTCCA
TTTTTAGGATGTCCATTTGGAATGTTCTGTCACAGATCTTCACTCTTAAAACTTTCCTATGTAA
GTAAATAATAATGTAAAAATGGAGCTGCCAGTTTTCTTTCTTTTACAAAAACAGTAAGTACTCG
ATGTTGCAGTATTTCCAGATTTAATGAAAGAACACAACTTAGTTTTTCAGTGAATTTAACATCT
TTCTATTTTTAAACTGATGAAATTTTTCTTTGGTAACTTGCAAGGATGAAATCACCTGTTTGCA
GTTTTTTTAAGCCTAATTTTGGCTTTATGGAGATTGCTTTATTGGTTACTTTAAAAGTCACCCT
TGCTTGCATTTCCCCCTATTTGACACATGAAAGCTGTGTTGGGTGTTTTACTGTACATACTTCA
AATGCACATAGGAATAGAAGTGTGTTATAAATCTAGCTTTCTTTATGATGTTTCTGATAATATT
GAGAATTGAAAACTTTACCTTCTCTTGTACATAGTCAGACTTTCTATACGTATTAAAGTTACAT
TTCATTCTAAGTTCAAAAGTTTGAAAATTATTAGTTTTGCAAGCTCAAACACTAATGTGACCAT
TTTATGAAGGGTGAAATGGATTTGTGTAGACAGTTCTAAACATAGAAATACAGTTACTAAATAT
TCAGGACCAATGCGAAATAACAAGAATGTAATGGAATTAGAATGAATTAAAGTAAGGTTGTATA
TTGAAAGTCATATTATAAAAGGTTTGCTTTTTTCAAGTGTTATTTATCTGAAATTATAATGGTT
AAGTGTTTGGAAACAAGTTTTGAACCATAAATTCAGCATAATTTCATTTGACTTCTCATTAATC
TTAGAAGCAATAAAAGAACCATTATTAAATATGTTGTAATGTTAAGATGTGAAGGTTCTTCCAA
AAACTTGTAAGGCTTTCCTAATCAATAGTAAACTCTTGTAGTTGATATTATTGCATACTAAATA
CAAGTTGCTGTTCTTTTCCCCTATATATTTGCTTAAGTATAAATTTCTTTATACAATCATTTCC
TTTAATTGTTGTAATTTAGTTACTTTCTAAAGATGCCAAAGGAAACAGATTTTTTTCTTTATTT
ATTTTAAATAGTTAAAACCCTGTACTTTTCTTTATGTTTTTGAAGTAAGGTTGAAATTGTGTGA
AAATGTGGACAGCTTTGTTCCATTGTTGATTAGAATTAATTTTTTTTTTTTTAGTGGAGGGTGG
CATGGTAATATTAGTAATATTTGGATTATTTTAAATATCAAACACTTCTACCCAGTTTACTATT
TGCCTATAGTAATGTTATCAGGGTATATTTAATTGTCCTGTGGTTTGACAGATGAGAGAGAACT
CAGAAGTTACTAAAGGTCAAGCATTACATACTTTGCTCTTGGAGGCAGCTATACCTTCCTTGCC
TGTGACTTTTATGCACATTAGCCCCTTAGGCTATACTCATCTAACTACAGTTTAACATCACCAG
TGCCCAGGAAATGGAAAAGTACAATATTTGGTATGAGAGGTTTTCCATAGGATTTTTCATGTCA
AAAATTTACCTCGTTTACATTTAATGTATCATCTCTTTCCTTTCTGGTACATTTCCCACTGTCA
TCTTCTGTTGTTTTTTTCATATTTTTCTACAGGTAGATTTATTTCCACAAACATAGAAATAAAG
ACAATTGCTTTTTTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001072139	(Get FASTA)	NCBI Sequence Viewer
	XP_013834060	(Get FASTA)	NCBI Sequence Viewer
	XP_020956180	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABI96188	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000036456.1
	ENSSSCP00000047545.2
	ENSSSCP00005002959.1
	ENSSSCP00005002973.1
	ENSSSCP00005002990.1
	ENSSSCP00015020703.1
	ENSSSCP00015020815.1
	ENSSSCP00025042059.1
	ENSSSCP00025042101.1
	ENSSSCP00030014025.1
	ENSSSCP00035025422.1
	ENSSSCP00035025425.1
	ENSSSCP00040009861.1
	ENSSSCP00040009873.1
	ENSSSCP00045029678.1
	ENSSSCP00045029778.1
	ENSSSCP00045029823.1
	ENSSSCP00050015801.1
	ENSSSCP00050015806.1
	ENSSSCP00050015809.1
	ENSSSCP00055029664.1
	ENSSSCP00060024799.1
	ENSSSCP00060024800.1
	ENSSSCP00065000501.1
	ENSSSCP00065000508.1
	ENSSSCP00070035162.1
	ENSSSCP00070035168.1
	ENSSSCP00070035174.1

RefSeq Acc Id:	XP_013834060 ⟸ XM_013978606
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D0HZS3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIE NLCAMGFDRNAVIVALSSKSWDVETATELLLSN hide sequence

RefSeq Acc Id:	XP_020956180 ⟸ XM_021100521
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D0HZS3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIE NLCAMGFDRNAVIVALSSKSWDVETATELLLSN hide sequence

RefSeq Acc Id:

NP_001072139 ⟸ NM_001078671

- UniProtKB:

Q06AB2 (UniProtKB/TrEMBL), A0A4X1V0N7 (UniProtKB/TrEMBL), A0A8D0NRW6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPE
TYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDA
VVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVET
ATELLLSN

hide sequence

RefSeq Acc Id:

ENSSSCP00000040258 ⟸ ENSSSCT00000043661

RefSeq Acc Id:

ENSSSCP00000047545 ⟸ ENSSSCT00000037743

RefSeq Acc Id:

ENSSSCP00000036456 ⟸ ENSSSCT00000047460

Protein Domains

UBA UBC core

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000033602	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00005003438	UniProtKB/TrEMBL
	ENSSSCG00015039046	UniProtKB/TrEMBL
	ENSSSCG00025069754	UniProtKB/TrEMBL
	ENSSSCG00030022438	UniProtKB/TrEMBL
	ENSSSCG00035047225	UniProtKB/TrEMBL
	ENSSSCG00040017324	UniProtKB/TrEMBL
	ENSSSCG00045025073	UniProtKB/TrEMBL
	ENSSSCG00050028343	UniProtKB/TrEMBL
	ENSSSCG00055019087	UniProtKB/TrEMBL
	ENSSSCG00060042746	UniProtKB/TrEMBL
	ENSSSCG00065001330	UniProtKB/TrEMBL
	ENSSSCG00070021076	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000037743.3	UniProtKB/TrEMBL
	ENSSSCT00000047460.3	UniProtKB/TrEMBL
	ENSSSCT00005005168.1	UniProtKB/TrEMBL
	ENSSSCT00005005191.1	UniProtKB/TrEMBL
	ENSSSCT00005005224.1	UniProtKB/TrEMBL
	ENSSSCT00015051898.1	UniProtKB/TrEMBL
	ENSSSCT00015052119.1	UniProtKB/TrEMBL
	ENSSSCT00025095805.1	UniProtKB/TrEMBL
	ENSSSCT00025095893.1	UniProtKB/TrEMBL
	ENSSSCT00030031166.1	UniProtKB/TrEMBL
	ENSSSCT00035062864.1	UniProtKB/TrEMBL
	ENSSSCT00035062872.1	UniProtKB/TrEMBL
	ENSSSCT00040023352.1	UniProtKB/TrEMBL
	ENSSSCT00040023383.1	UniProtKB/TrEMBL
	ENSSSCT00045042740.1	UniProtKB/TrEMBL
	ENSSSCT00045042874.1	UniProtKB/TrEMBL
	ENSSSCT00045042933.1	UniProtKB/TrEMBL
	ENSSSCT00050038112.1	UniProtKB/TrEMBL
	ENSSSCT00050038124.1	UniProtKB/TrEMBL
	ENSSSCT00050038129.1	UniProtKB/TrEMBL
	ENSSSCT00055037337.1	UniProtKB/TrEMBL
	ENSSSCT00060057953.1	UniProtKB/TrEMBL
	ENSSSCT00060057954.1	UniProtKB/TrEMBL
	ENSSSCT00065001622.1	UniProtKB/TrEMBL
	ENSSSCT00065001636.1	UniProtKB/TrEMBL
	ENSSSCT00070041866.1	UniProtKB/TrEMBL
	ENSSSCT00070041872.1	UniProtKB/TrEMBL
	ENSSSCT00070041880.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.110.10	UniProtKB/TrEMBL
	DNA helicase RuvA subunit, C-terminal domain	UniProtKB/TrEMBL
InterPro	UBA	UniProtKB/TrEMBL
	UBA-like_sf	UniProtKB/TrEMBL
	UBE2K_UBA	UniProtKB/TrEMBL
	UBQ-conjugat_E2	UniProtKB/TrEMBL
	UBQ-conjugating_AS	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
KEGG Report	ssc:780416	UniProtKB/TrEMBL
NCBI Gene	UBE2K	ENTREZGENE
PANTHER	E2 UBIQUITIN-CONJUGATING ENZYME	UniProtKB/TrEMBL
	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
	UBIQUITIN-CONJUGATING ENZYME E2 K	UniProtKB/TrEMBL
Pfam	UBA	UniProtKB/TrEMBL
	UQ_con	UniProtKB/TrEMBL
PROSITE	UBA	UniProtKB/TrEMBL
	UBIQUITIN_CONJUGAT_1	UniProtKB/TrEMBL
	UBIQUITIN_CONJUGAT_2	UniProtKB/TrEMBL
SMART	UBA	UniProtKB/TrEMBL
	UBCc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46934	UniProtKB/TrEMBL
	SSF54495	UniProtKB/TrEMBL
UniProt	A0A286ZXT8_PIG	UniProtKB/TrEMBL
	A0A287AUE4_PIG	UniProtKB/TrEMBL
	A0A4X1V0N7	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1V393_PIG	UniProtKB/TrEMBL
	A0A4X1V398_PIG	UniProtKB/TrEMBL
	A0A8D0HZS3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0I349_PIG	UniProtKB/TrEMBL
	A0A8D0NRW6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0W001_PIG	UniProtKB/TrEMBL
	Q06AB2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:94646	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar