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ONTOLOGY REPORT - ANNOTATIONS

Term:chromosome, telomeric repeat region
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Accession:GO:0140445 term browser browse the term
Definition:A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop.


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chromosome, telomeric repeat region term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rif1 replication timing regulatory factor 1 is_active_in IDA (MGI:5584328|PMID:24735877) BHF-UCL PMID:24735877 MGI:5584328 NCBI chr 2:51,962,725...52,016,781
Ensembl chr 2:51,962,844...52,012,395 		JBrowse link
CST complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctc1 CTS telomere maintenance complex component 1 part_of IDA
ISO
IBA		 (MGI:4441108|PMID:19854130) UniProt
MGI
GO_Central		 PMID:19854130 GO_REF:0000033 GO_REF:0000119 MGI:4441108 MGI:4834177 NCBI chr11:68,906,014...68,927,299
Ensembl chr11:68,906,737...68,927,299 		JBrowse link
G Stn1 STN1, CST complex subunit part_of IDA
ISO
IBA		 (MGI:4441108|PMID:19854130) UniProt
MGI
GO_Central		 PMID:19854130 GO_REF:0000033 GO_REF:0000119 MGI:4441108 MGI:4834177 NCBI chr19:47,489,470...47,534,284
Ensembl chr19:47,489,472...47,525,946 		JBrowse link
G Ten1 TEN1 telomerase capping complex subunit part_of IDA
ISO
IBA		 (MGI:4441108|PMID:19854130) UniProt
MGI
GO_Central		 PMID:19854130 GO_REF:0000033 GO_REF:0000119 MGI:4441108 MGI:4834177 NCBI chr11:116,089,681...116,106,144
Ensembl chr11:116,089,681...116,106,144 		JBrowse link
nuclear telomere cap complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd adrenocortical dysplasia part_of IDA
ISO		 (MGI:3829120|PMID:18185984) BHF-UCL
MGI		 PMID:18185984 GO_REF:0000119 MGI:3829120 MGI:4834177 NCBI chr 8:106,424,789...106,427,748
Ensembl chr 8:106,422,492...106,427,734 		JBrowse link
G Pot1a protection of telomeres 1A part_of ISO
IDA
IBA		 (PMID:17053789) MGI
GO_Central		 PMID:17053789 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 6:25,743,939...25,809,280
Ensembl chr 6:25,743,736...25,809,245 		JBrowse link
G Pot1b protection of telomeres 1B part_of ISO
IBA
IDA		 (PMID:17053789) MGI
GO_Central		 PMID:17053789 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:55,958,190...56,019,647
Ensembl chr17:55,958,951...56,019,628 		JBrowse link
G Terf1 telomeric repeat binding factor 1 part_of IDA
IBA
ISO		 (MGI:77658|PMID:7502076) BHF-UCL
GO_Central
MGI		 PMID:7502076 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:77658 NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276 		JBrowse link
G Terf2 telomeric repeat binding factor 2 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179 		JBrowse link
G Terf2ip telomeric repeat binding factor 2, interacting protein part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:112,737,991...112,747,160
Ensembl chr 8:112,738,030...112,747,160 		JBrowse link
G Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:55,912,120...55,919,265
Ensembl chr14:55,912,146...55,919,277 		JBrowse link
shelterin complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd adrenocortical dysplasia part_of
located_in		 IBA
ISO		 (PMID:15383534) GO_Central
ComplexPortal
MGI		 PMID:15383534 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:106,424,789...106,427,748
Ensembl chr 8:106,422,492...106,427,734 		JBrowse link
G Pot1a protection of telomeres 1A part_of
located_in		 ISO (PMID:15383534) MGI
ComplexPortal		 PMID:15383534 GO_REF:0000119 MGI:4834177 NCBI chr 6:25,743,939...25,809,280
Ensembl chr 6:25,743,736...25,809,245 		JBrowse link
G Pot1b protection of telomeres 1B part_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:55,958,190...56,019,647
Ensembl chr17:55,958,951...56,019,628 		JBrowse link
G Terb1 telomere repeat binding bouquet formation protein 1 part_of IDA (MGI:5704279|PMID:26548954) UniProt PMID:26548954 MGI:5704279 NCBI chr 8:105,173,350...105,236,692
Ensembl chr 8:105,173,351...105,236,542 		JBrowse link
G Terf1 telomeric repeat binding factor 1 part_of
located_in		 ISO (PMID:15383534) MGI
ComplexPortal		 PMID:15383534 GO_REF:0000119 MGI:4834177 NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276 		JBrowse link
G Terf2 telomeric repeat binding factor 2 part_of
located_in		 IBA
ISO		 (PMID:15383534) GO_Central
ComplexPortal
MGI		 PMID:15383534 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179 		JBrowse link
G Terf2ip telomeric repeat binding factor 2, interacting protein part_of IBA
ISO		 GO_Central
MGI		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:112,737,991...112,747,160
Ensembl chr 8:112,738,030...112,747,160 		JBrowse link
G Tinf2 Terf1 (TRF1)-interacting nuclear factor 2 part_of
located_in		 IBA
ISO		 (PMID:15383534) GO_Central
ComplexPortal
MGI		 PMID:15383534 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr14:55,912,120...55,919,265
Ensembl chr14:55,912,146...55,919,277 		JBrowse link
telomere cap complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 part_of IDA (PMID:28031483) MGI PMID:28031483 NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      chromosomal region 389
        chromosome, telomeric region 134
          chromosome, telomeric repeat region 12
            telomere cap complex + 11
Path 2
Term Annotations click to browse term
  cellular_component 28585
    cellular anatomical entity 19619
      organelle 13553
        non-membrane-bounded organelle 4912
          intracellular non-membrane-bounded organelle 4909
            chromosome 1486
              chromosomal region 389
                chromosome, telomeric region 134
                  chromosome, telomeric repeat region 12
                    telomere cap complex + 11
paths to the root