Ten1 (TEN1 telomerase capping complex subunit)

Gene: Ten1 (TEN1 telomerase capping complex subunit) Mus musculus

Analyze

Symbol:

Ten1

Name:

TEN1 telomerase capping complex subunit

RGD ID:

1322344

MGI Page

MGI

Description:

Predicted to enable telomerase inhibitor activity and telomeric DNA binding activity. Predicted to be involved in negative regulation of telomere maintenance via telomerase. Located in chromosome, telomeric region and nucleus. Part of CST complex. Orthologous to human TEN1 (TEN1 subunit of CST complex).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2310004N24Rik; CST complex subunit TEN1; protein telomeric pathways with STN1 homolog; RP23-174D24.1; telomere length regulation protein TEN1 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TEN1 (TEN1 subunit of CST complex)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Ten1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ten1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TEN1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TEN1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ten1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TEN1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TEN1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ten1 (TEN1 subunit of CST complex)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TEN1-CDK3 (TEN1-CDK3 readthrough (NMD candidate))	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Ten1 (TEN1 subunit of CST complex)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TEN1 (TEN1 subunit of CST complex)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ten1 (TEN1 subunit of CST complex)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	ten1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	116,089,681 - 116,106,144 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	116,089,681 - 116,106,144 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	116,198,855 - 116,215,318 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	116,198,855 - 116,215,318 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	116,060,169 - 116,076,632 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	116,015,005 - 116,031,410 (+)	NCBI		MGSCv36	mm8
Celera	11	127,963,514 - 127,979,990 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	81.0	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

peroxisomal acyl-CoA oxidase deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3',4,4',5-Pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (EXP)

6-propyl-2-thiouracil (ISO)

amitrole (ISO)

antirheumatic drug (ISO)

atrazine (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

clobetasol (EXP)

cobalt dichloride (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (EXP)

furan (ISO)

glyphosate (ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (ISO)

phytoestrogen (ISO)

sulfadimethoxine (ISO)

trichloroethene (EXP)

troglitazone (EXP)

tungsten (EXP)

urethane (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of telomere maintenance via telomerase (IBA,ISO)

Cellular Component

chromosome (IEA)

chromosome, telomeric region (IDA,ISO)

CST complex (IBA,IDA,ISO)

nucleoplasm (ISO)

nucleus (IDA,ISO)

Molecular Function

DNA binding (IEA)

protein binding (ISO)

single-stranded DNA binding (IEA)

telomerase inhibitor activity (IBA)

telomeric DNA binding (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10512203	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:14610273	PMID:15840001	PMID:16141072	PMID:16141073
PMID:16602821	PMID:18799693	PMID:19854130	PMID:21267068	PMID:21873635	PMID:23604909	PMID:26496610	PMID:32325033	PMID:32554809

Genomics

Comparative Map Data

Ten1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	116,089,681 - 116,106,144 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	116,089,681 - 116,106,144 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	116,198,855 - 116,215,318 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	116,198,855 - 116,215,318 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	116,060,169 - 116,076,632 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	116,015,005 - 116,031,410 (+)	NCBI		MGSCv36	mm8
Celera	11	127,963,514 - 127,979,990 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	81.0	NCBI

TEN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	75,979,240 - 76,000,586 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	75,979,240 - 76,000,586 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	73,975,321 - 73,996,667 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Celera	17	70,565,337 - 70,586,706 (+)	NCBI		Celera
Cytogenetic Map	17	q25.1	NCBI
HuRef	17	69,400,902 - 69,422,270 (+)	NCBI		HuRef
CHM1_1	17	74,040,123 - 74,061,496 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	76,872,369 - 76,893,714 (+)	NCBI		T2T-CHM13v2.0

Ten1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	101,930,212 - 101,951,932 (+)	NCBI		GRCr8
mRatBN7.2	10	101,431,328 - 101,455,105 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	101,431,328 - 101,453,052 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	106,493,729 - 106,509,859 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	105,956,825 - 105,972,955 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	101,352,246 - 101,373,967 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	105,073,077 - 105,095,094 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	105,073,077 - 105,095,094 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	104,741,402 - 104,763,320 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	106,318,384 - 106,327,849 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	106,332,933 - 106,342,262 (+)	NCBI
Celera	10	100,004,601 - 100,026,088 (+)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

Ten1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	6,250,726 - 6,287,093 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	6,252,146 - 6,286,675 (-)	NCBI	ChiLan1.0	ChiLan1.0

TEN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	92,022,983 - 92,041,784 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	96,848,002 - 96,866,791 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	69,928,204 - 69,947,138 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	75,479,181 - 75,498,018 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	75,479,181 - 75,498,018 (+)	Ensembl	panpan1.1		panPan2

TEN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	4,635,192 - 4,658,455 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	4,635,354 - 4,658,252 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	5,315,681 - 5,339,051 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	5,305,546 - 5,328,957 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	5,305,708 - 5,328,612 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	5,345,451 - 5,368,827 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	5,454,878 - 5,478,252 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	5,515,401 - 5,538,769 (-)	NCBI		UU_Cfam_GSD_1.0

Ten1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	5,251,253 - 5,272,075 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	1,140,003 - 1,159,618 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	1,139,926 - 1,159,611 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TEN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	5,430,840 - 5,451,121 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	5,430,940 - 5,451,140 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	5,386,232 - 5,406,421 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TEN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	45,686,946 - 45,706,185 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	16,435,709 - 16,459,002 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ten1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	5,880,221 - 5,900,121 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	5,867,474 - 5,900,298 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ten1
680 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	707
Count of miRNA genes:	373
Interacting mature miRNAs:	414
Transcripts:	ENSMUST00000021130, ENSMUST00000124663, ENSMUST00000135460, ENSMUST00000146066
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12268637	118022724	Mouse
1301072	Eae22_m	experimental allergic encephalomyelitis 22 (mouse)			Not determined		11	82377698	116377820	Mouse
14747003	Mancz9_m	mandible centroid size 9 (mouse)					11	85844911	119844911	Mouse
15039374	Adip29_m	adiposity 29 (mouse)					11	86608320	120608320	Mouse
15039376	Bw42_m	body weight QTL 42 (mouse)					11	86608320	120608320	Mouse
15014785	Mvlq1_m	macrovesicular liver lesion QTL 1 (mouse)					11	86608320	120608320	Mouse
27226789	Feml16_m	femur length 16, 10 week (mouse)					11	87490826	121873369	Mouse
10044007	Hbnr14_m	Heligmosomoides bakeri nematode resistance 14 (mouse)			Not determined		11	87502600	121502698	Mouse
11251723	Ewc5_m	ethanol withdrawal and consumption 5 (mouse)					11	89869251	121973369	Mouse
1558753	Ath19_m	atherosclerosis 19 (mouse)			Not determined		11	91604608	121973369	Mouse
1302034	Pkccl_m	protein kinase C content in lungs (mouse)			Not determined		11	91604608	121973369	Mouse
1301095	El6_m	epilepsy 6 (mouse)			Not determined		11	93229183	121973369	Mouse
4141939	Pregq2_m	pregnancy QTL 2 (mouse)			Not determined		11	94063779	118022724	Mouse
27226731	Tibmd4_m	tibia midshaft diameter 4, 10 week (mouse)					11	94190826	118890826	Mouse
4141465	Dbm2_m	diabetes modifier 2 (mouse)			Not determined			94437183	118022724	Mouse
1301958	Alcp18_m	alcohol preference locus 18 (mouse)			Not determined		11	95403965	121973369	Mouse
1300944	Alcp20_m	alcohol preference locus 20 (mouse)			Not determined		11	95403965	121973369	Mouse
1300962	Cd8mts4_m	CD8 memory T cell subset 4 (mouse)			Not determined		11	96137674	121973369	Mouse
1301057	Nidd4_m	non-insulin-dependent diabetes mellitus 4 (mouse)			Not determined		11	96810136	121973369	Mouse
1301983	Berr2_m	berghei resistance locus 2 (mouse)			Not determined		11	98352609	121973369	Mouse
10043976	Obq33_m	obesity QTL 33 (mouse)			Not determined		11	98500469	121973369	Mouse
10044001	Alcw8_m	alcohol withdrawal 8 (mouse)			Not determined		11	99254187	121973369	Mouse
11553867	Stmm5_m	skin tumor modifier of MSM 5 (mouse)					11	100058103	121973369	Mouse
11341721	Rvfs2_m	Rift Valley fever susceptibility 2 (mouse)					11	100254186	120887165	Mouse
1301012	Vispl_m	visual placing (mouse)			Not determined		11	101022590	121973369	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_027107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK009156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK153854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL669925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC027639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ030877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000021130 ⟹ ENSMUSP00000021130

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	116,089,681 - 116,106,144 (+)	Ensembl
GRCm38.p6 Ensembl	11	116,198,855 - 116,215,318 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000124663

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	116,089,724 - 116,097,676 (+)	Ensembl
GRCm38.p6 Ensembl	11	116,198,898 - 116,206,850 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000135460

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	116,101,760 - 116,106,074 (+)	Ensembl
GRCm38.p6 Ensembl	11	116,210,934 - 116,215,248 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000146066

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	116,089,785 - 116,106,074 (+)	Ensembl
GRCm38.p6 Ensembl	11	116,198,959 - 116,215,248 (+)	Ensembl

RefSeq Acc Id:

NM_027107 ⟹ NP_081383

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	116,089,681 - 116,106,144 (+)	NCBI
GRCm38	11	116,198,855 - 116,215,318 (+)	ENTREZGENE
MGSCv37	11	116,060,169 - 116,076,632 (+)	RGD
Celera	11	127,963,514 - 127,979,990 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

CCCGTCCCCGCCGCCACTCCTCACGTGACCGGCTGCAATCCCCGACGCTGGTACCGCCCGCCGG
ACGGACGAATCCCCTGCTGCGGGCCAGGGGAGGTCCCCGAGCGGCTCCTCGCCAAGGAAAGCAA
GGAATCTTCAAAGTCCCTTGCCAACGATTTGGATCCTGGTGCTGACAATGTTGCCTAAGCCTGG
GGTCTATTACTTTCCCTGGGAGGTCAGTGACGGCCATGTCCCCGAAGGAAGCACACTGCGAACA
TTTGGCAGGTTGTATCTCTATGACATGGCACGCTCCCTCATGACCCTGGCAGCTCCGCAGAAAC
CTGATCAGTGTCAACTGCTTGTCTGCACCAACTTGGTGGAGCCTTTTGAGGCACATGTGAACTT
CCTGTACATGGTTCTTGGGGACCTGGAGCGAATGGAGGGTGGAGCTTTTGTGGTGAGGGCCCGA
CTGCTCACCTGTGTGGAGGGGATGGATTTGTCCCTGTTAGAGAAAGCCATCTTGGAGCAGAGGC
GTCACCTGCAGAAGAGGCAGCAGCCAATAGGAGACGCCAGCACCTTGCAAACCCCTACACCTGC
TCCTCAATCGATTCCCAGTGACAGCCTTAGTCTGGAACCAGAGAACAGGGGGCAGCAGGTGCCC
CTTCCCCAAACTCTGGACTGAGCAGAAAGCCCACCCAATCTGGCCGTAGTGGCCCATGCTGCAA
TCCCAGTGCAGGCAGGGAGAGGCGGGAAGAGGTGGAGTTTAAAGCCAGTCTGAGCTACATAACA
CATATGCCCTCTCTCTCTCAAAGAAGAAGAAGAATGAAAATGAATATGATTCCCTACCCCAGGG
CCCTGGCGCTGTGGCTTGTGAGGGATGTGAAGGGTTCCTGAATGCCTCATGAATAAAGAGTATA
AGCGTAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_081383	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH27639	(Get FASTA)	NCBI Sequence Viewer
	BAB26112	(Get FASTA)	NCBI Sequence Viewer
	BAE27018	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000021130
	ENSMUSP00000021130.7
GenBank Protein	Q9D7K2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_081383 ⟸ NM_027107
- UniProtKB:	Q9D7K2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MLPKPGVYYFPWEVSDGHVPEGSTLRTFGRLYLYDMARSLMTLAAPQKPDQCQLLVCTNLVEPF EAHVNFLYMVLGDLERMEGGAFVVRARLLTCVEGMDLSLLEKAILEQRRHLQKRQQPIGDASTL QTPTPAPQSIPSDSLSLEPENRGQQVPLPQTLD hide sequence

RefSeq Acc Id:

ENSMUSP00000021130 ⟸ ENSMUST00000021130

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9D7K2-F1-model_v2	AlphaFold	Q9D7K2	1-161	view protein structure

Promoters

RGD ID:

6821794

Promoter ID:

MM_KWN:10628

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day4, Liver, MEF_B6

Transcripts:

OTTMUST00000008447, OTTMUST00000008448, OTTMUST00000008450

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	116,059,419 - 116,059,919 (+)	MPROMDB

RGD ID:

8677434

Promoter ID:

EPDNEW_M16748

Type:

initiation region

Name:

Ten1_1

Description:

Mus musculus TEN1 telomerase capping complex subunit , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	116,198,870 - 116,198,930	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1916785	AgrOrtholog
Ensembl Genes	ENSMUSG00000020778	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000021130	ENTREZGENE
	ENSMUST00000021130.7	UniProtKB/Swiss-Prot
Gene3D-CATH	2.40.50.140	UniProtKB/Swiss-Prot
InterPro	NA-bd_OB-fold	UniProtKB/Swiss-Prot
	Ten1_animal_plant	UniProtKB/Swiss-Prot
KEGG Report	mmu:69535	UniProtKB/Swiss-Prot
MGD	MGI:1916785	ENTREZGENE
NCBI Gene	69535	ENTREZGENE
PANTHER	CST COMPLEX SUBUNIT TEN1	UniProtKB/Swiss-Prot
	PTHR33905	UniProtKB/Swiss-Prot
Pfam	Ten1_2	UniProtKB/Swiss-Prot
PhenoGen	Ten1	PhenoGen
UniProt	Q9D7K2	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-07-31	Ten1	TEN1 telomerase capping complex subunit	2310004N24Rik	RIKEN cDNA 2310004N24 gene	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar