Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:ligand-gated calcium channel activity
go back to main search page
Accession:GO:0099604 term browser browse the term
Definition:Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


show annotations for term's descendants           Sort by:
ligand-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCOLN1 mucolipin TRP cation channel 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G P2RX1 purinergic receptor P2X 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:47,674,175...47,694,358
Ensembl chr 9:47,675,300...47,688,858 		JBrowse link
G P2RX4 purinergic receptor P2X 4 enables IEA Ensembl GO_REF:0000107 NCBI chr26:7,897,528...7,914,279
Ensembl chr26:7,898,015...7,914,234 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
G TRPM5 transient receptor potential cation channel subfamily M member 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr18:46,479,397...46,493,279
Ensembl chr18:46,478,759...46,498,043 		JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr25:45,261,092...45,357,560
Ensembl chr25:45,261,107...45,353,282 		JBrowse link
calcium-induced calcium release activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP1 BCL2 interacting protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:39,255,685...39,303,485
Ensembl chr 4:39,289,776...39,303,430 		JBrowse link
G FAM98C family with sequence similarity 98 member C enables IEA Ensembl GO_REF:0000107 NCBI chr 1:114,598,841...114,602,316
Ensembl chr 1:114,597,464...114,602,708 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel enables IEA Ensembl GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438 		JBrowse link
G RYR1 ryanodine receptor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 enables ISO
IEA		 RGD
Ensembl		 PMID:18799678 GO_REF:0000107 RGD:7175259 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 ISO RGD PMID:18799678 RGD:7175259 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
glutamate-gated calcium ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 enables ISO PMID:1709304
PMID:11773314		 UniProt PMID:1709304 PMID:11773314 RGD:401966868 RGD:401966871 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 enables ISO PMID:11773314 UniProt PMID:11773314 RGD:401966871 NCBI chr15:54,634,332...54,710,711
Ensembl chr15:54,634,335...54,708,184 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 enables ISO PMID:1709304 UniProt PMID:1709304 RGD:401966868 NCBI chr  X:94,729,828...95,006,244
Ensembl chr  X:94,730,943...95,004,279 		JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 enables ISO PMID:11425885
PMID:12873388		 UniProt PMID:11425885 PMID:12873388 RGD:405650374 RGD:405650399 NCBI chr31:24,477,319...24,839,502
Ensembl chr31:24,478,696...24,839,434 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 enables ISO PMID:7681676 UniProt PMID:7681676 RGD:405650269 NCBI chr12:58,932,754...59,991,305
Ensembl chr12:59,355,017...59,990,408 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 enables ISO (PMID:26875626) UniProt PMID:26875626 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A enables IEA Ensembl GO_REF:0000107 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B enables IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C enables IEA Ensembl GO_REF:0000107 NCBI chr 9:5,582,404...5,595,540
Ensembl chr 9:5,576,681...5,595,146 		JBrowse link
G GRIN2D glutamate ionotropic receptor NMDA type subunit 2D enables IEA Ensembl GO_REF:0000107 NCBI chr 1:107,821,853...107,853,411
Ensembl chr 1:107,822,716...107,849,945 		JBrowse link
inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
inositol 1,4,5-trisphosphate-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro
UniProt		 PMID:15533917 PMID:19036964 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:6480876 RGD:7175271 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:10969001 PMID:15533917 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:7175271 RGD:7175277 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 enables ISO
IEA		 RGD
Ensembl
UniProt
InterPro		 PMID:10694253 PMID:15533917 PMID:17320950 PMID:17373911 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 RGD:2290285 RGD:7175265 RGD:7175268 RGD:7175271 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
intracellularly gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 enables IEA Ensembl GO_REF:0000107 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 enables IEA Ensembl GO_REF:0000107 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
G RASA3 RAS p21 protein activator 3 enables IEA Ensembl GO_REF:0000107 NCBI chr22:61,093,762...61,202,209
Ensembl chr22:61,095,044...61,202,152 		JBrowse link
G RYR2 ryanodine receptor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 enables ISS UniProt GO_REF:0000024 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926 		JBrowse link
NAADP-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCOLN1 mucolipin TRP cation channel 1 enables ISO
IEA		 RGD
TreeGrafter		 PMID:17613490 GO_REF:0000118 RGD:7205504 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MCOLN2 mucolipin TRP cation channel 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:62,956,797...63,008,527
Ensembl chr 6:62,956,804...63,200,612 		JBrowse link
G MCOLN3 mucolipin TRP cation channel 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:62,923,598...62,953,696
Ensembl chr 6:62,923,267...62,953,564 		JBrowse link
G TPCN1 two pore segment channel 1 NOT|enables ISO
IEA		 (PMID:24776928)
(MGI:6718238|PMID:24776928)		 UniProt
Ensembl		 PMID:24776928 GO_REF:0000107 MGI:6718238 NCBI chr26:10,599,898...10,662,269
Ensembl chr26:10,599,780...10,660,767 		JBrowse link
G TPCN2 two pore segment channel 2 NOT|enables ISO
IEA		 (PMID:23063126) UniProt
Ensembl		 PMID:23063126 GO_REF:0000107 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM98C family with sequence similarity 98 member C enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:114,598,841...114,602,316
Ensembl chr 1:114,597,464...114,602,708 		JBrowse link
G RYR1 ryanodine receptor 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:19230144 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:7175256 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:18799678 PMID:21807619 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:7175254 RGD:7175259 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 enables ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:18799678 GO_REF:0000002 GO_REF:0000118 RGD:7175259 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        monoatomic ion transmembrane transporter activity 768
          monoatomic ion channel activity 468
            monoatomic cation channel activity 360
              calcium channel activity 128
                ligand-gated calcium channel activity 33
                  glutamate-gated calcium ion channel activity 10
                  intracellularly gated calcium channel activity + 18
                  pH-gated calcium channel activity 0
Path 2
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        passive transmembrane transporter activity 533
          channel activity 533
            gated channel activity 333
              ligand-gated channel activity 191
                ligand-gated monoatomic ion channel activity 187
                  ligand-gated monoatomic cation channel activity 134
                    ligand-gated calcium channel activity 33
                      glutamate-gated calcium ion channel activity 10
                      intracellularly gated calcium channel activity + 18
                      pH-gated calcium channel activity 0
paths to the root