Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive T cell selection
go back to main search page
Accession:GO:0043368 term browser browse the term
Definition:The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
Synonyms:exact_synonym: positive T lymphocyte selection

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
positive T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL11B BCL11 transcription factor B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17998389) MGI
Ensembl		 PMID:17998389 GO_REF:0000107 NCBI chr24:77,122,591...77,222,562
Ensembl chr24:77,122,689...77,221,454 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:23334952) MGI PMID:23334952 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G THEMIS thymocyte selection associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:45,665,494...45,886,672
Ensembl chr13:45,682,663...45,884,856 		JBrowse link
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) MGI PMID:18228248 NCBI chr21:109,495,525...109,690,261 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:109,545,491...109,690,195 JBrowse link
G CYLD CYLD lysine 63 deubiquitinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16501569) Ensembl
MGI		 PMID:16501569 GO_REF:0000107 NCBI chr 5:36,541,022...36,600,874
Ensembl chr 5:36,541,764...36,595,417 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
CD4-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSL cathepsin L involved_in ISO (PMID:9545226) UniProt PMID:9545226 NCBI chr12:98,347,770...98,353,426
Ensembl chr12:98,347,800...98,353,467 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091 		JBrowse link
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091 		JBrowse link
CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8170972) MGI
Ensembl		 PMID:8170972 GO_REF:0000107 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:71,302,082...71,400,201
Ensembl chr18:71,310,577...71,345,960 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD69 CD69 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:9,659,154...9,666,342
Ensembl chr11:9,659,029...9,665,914 		JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,301,760...16,323,343
Ensembl chr 6:16,300,525...16,322,859 		JBrowse link
G LGALS1 galectin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:20,379,144...20,383,303
Ensembl chr19:20,379,003...20,383,464 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:32,722,588...32,745,480
Ensembl chr14:32,725,112...32,745,004 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (PMID:24107315) UniProt PMID:24107315 NCBI chr25:56,105,757...56,118,249
Ensembl chr25:56,106,584...56,118,758 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr17:39,113,519...39,126,267 JBrowse link
G BRD2 bromodomain containing 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:39,114,700...39,122,051 JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr 6:13,836,332...13,883,459
Ensembl chr 6:13,836,324...13,873,877 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:52,289,486...52,296,735
Ensembl chr11:52,295,106...52,297,244 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:87,679,656...87,778,767
Ensembl chr15:87,679,077...87,779,102 		JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426) MGI PMID:9133426 NCBI chr20:5,726,307...5,733,355
Ensembl chr20:5,727,049...5,730,061 		JBrowse link
G CD3D CD3d molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:109,715,148...109,719,576
Ensembl chr 1:109,713,017...109,719,950 		JBrowse link
G CD3E CD3e molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,681,142...109,692,835
Ensembl chr 1:109,681,065...109,692,839 		JBrowse link
G CD3G CD3g molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:109,721,150...109,730,267
Ensembl chr 1:109,720,789...109,732,014 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9432982)
(PMID:7679955), (PMID:8598040)		 MGI
Ensembl		 PMID:7679955 PMID:8598040 PMID:9432982 GO_REF:0000107 NCBI chr23:53,008,802...53,022,953
Ensembl chr23:53,009,394...53,022,923 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12871644) Ensembl
MGI		 PMID:12871644 GO_REF:0000107 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064401) Ensembl
MGI		 PMID:15064401 GO_REF:0000107 NCBI chr25:3,009,464...3,117,729
Ensembl chr25:3,009,353...3,118,235 		JBrowse link
G LOC103241092 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7630421) MGI
Ensembl		 PMID:7630421 GO_REF:0000107 NCBI chr14:1,403,294...1,430,205
Ensembl chr14:1,404,325...1,431,015 		JBrowse link
G MHC-DMA HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8638109)
(PMID:8598041), (PMID:9432982)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr17:39,142,340...39,151,804
Ensembl chr17:39,142,395...39,146,252 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 involved_in ISO (PMID:17579027) UniProt PMID:17579027 NCBI chr 5:59,193,139...59,346,361 JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8666928) Ensembl
MGI		 PMID:8666928 GO_REF:0000107 NCBI chr25:30,655,014...30,777,367
Ensembl chr25:30,653,044...30,777,303 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SRF serum response factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21098124) MGI
Ensembl		 PMID:21098124 GO_REF:0000107 NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995 		JBrowse link
G STK11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21487392) Ensembl
MGI		 PMID:21487392 GO_REF:0000107 NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136 		JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXN1 forkhead box N1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,291,597...22,306,977
Ensembl chr16:22,292,330...22,305,968 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,777,490...55,086,819
Ensembl chr 8:54,776,015...54,927,091 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) MGI PMID:20706986 NCBI chr23:35,492,158...35,501,349
Ensembl chr23:35,492,939...35,501,258 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G SPN sialophorin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,987,810...26,990,214 JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) Ensembl
MGI		 PMID:20706986 GO_REF:0000107 NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:68,131,258...68,145,579
Ensembl chr16:68,131,536...68,144,415 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:52,761,569...52,785,999
Ensembl chr24:52,761,651...52,785,978 		JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:27893700)
(PMID:16990136)		 UniProt PMID:16990136 PMID:27893700 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in ISO (PMID:22983707) UniProt PMID:22983707 NCBI chr17:71,739,920...71,758,811 JBrowse link
G IRF4 interferon regulatory factor 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:71,751,770...71,757,496 JBrowse link
G LY9 lymphocyte antigen 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,140,059...3,145,818 JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (PMID:25470037) MGI PMID:25470037 NCBI chr  X:46,041,348...46,077,195 JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:3,426,868...3,465,553
Ensembl chr20:3,453,370...3,463,901 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    immune system process 2668
      T cell selection 66
        positive T cell selection 51
          CD4-positive or CD8-positive, alpha-beta T cell lineage commitment + 34
          positive extrathymic T cell selection 0
          positive thymic T cell selection + 17
Path 2
Term Annotations click to browse term
  biological_process 19806
    developmental process 6822
      cellular developmental process 4575
        cell differentiation 4574
          cell development 3260
            hemopoiesis 1051
              leukocyte differentiation 683
                mononuclear cell differentiation 554
                  lymphocyte differentiation 453
                    T cell differentiation 338
                      T cell selection 66
                        positive T cell selection 51
                          CD4-positive or CD8-positive, alpha-beta T cell lineage commitment + 34
                          positive extrathymic T cell selection 0
                          positive thymic T cell selection + 17
paths to the root