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ONTOLOGY REPORT - ANNOTATIONS

Term:apoptosome
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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota


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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of
located_in		 IDA
ISO
IEA		 PMID:26265044
(PMID:21827945)
(PMID:10206961)
GO_REF:0000002		 RGD
InterPro		 PMID:10206961 PMID:21827945 PMID:17483091 PMID:26265044 GO_REF:0000002, RGD:2325744, RGD:11079191 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Casp9 caspase 9 part_of
located_in		 ISO (PMID:21827945)
(PMID:10206961)		 RGD PMID:10206961 PMID:21827945 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cycs cytochrome c, somatic located_in ISO (PMID:10206961) RGD PMID:10206961 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (PMID:15271982) RGD PMID:15271982 NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20629
    protein-containing complex 6604
      apoptosome 4
Path 2
Term Annotations click to browse term
  cellular_component 20629
    cellular anatomical entity 20391
      intracellular anatomical structure 15013
        cytoplasm 11695
          cytosol 4174
            apoptosome 4
paths to the root