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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of IDA
RGD PMID:21827945, PMID:17483091, PMID:26265044 RGD:2325744, RGD:11079191 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Casp9 caspase 9 part_of ISO (PMID:21827945) RGD PMID:21827945 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) RGD PMID:15271982 MGI:3056865 NCBI chr 8:65,686,586...65,774,940
Ensembl chr 8:65,686,648...65,774,989
JBrowse link

Term paths to the root
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  cellular_component 20142
    protein-containing complex 6031
      apoptosome 3
Path 2
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  cellular_component 20142
    cellular anatomical entity 19842
      intracellular anatomical structure 14431
        cytoplasm 11416
          cytosol 4243
            apoptosome 3
paths to the root